Fournier's gangrene due to rectal cancer: A case report

  • Authors:
    • Sen Hou
    • Baosen Cheng
    • Kai Shen
    • Zhidong Gao
    • Fan Liu
    • Yingjiang Ye
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  • Published online on: February 12, 2024     https://doi.org/10.3892/mco.2024.2728
  • Article Number: 30
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Abstract

Fournier's gangrene (FG) is an extremely rare necrotizing fasciitis that is insidious, rapidly spreading and life‑threatening. FGs due to rectal cancer occur rarely and there is a lack of clinical reference. In the present study, a severe FG due to rectal cancer perforation was described and the features of this rare disease were summarized with a literature review. A 57‑year‑old man was admitted because of rectal cancer‑induced FG. The patient was misdiagnosed with extensive perianal abscess until the intraoperative biopsy confirmed that rectal cancer was the culprit. Incision, debridement and drainage were carried out to reduce infectious burdens. After that, the patient was transferred to Peking University People's Hospital for the subsequent therapy. Empirical broad‑spectrum antibiotic therapy was used at the initial stage. Diversional transverse loop colostomy was performed to control infection and resume oral feeding. After four rounds of vacuum‑assisted closure (VAC) therapy, radical resection and wound closure were accomplished. The scrotal defect was repaired by a skin flap. Pathological results indicated a moderately differentiated adenocarcinoma with perforation. The patient was discharged from the hospital on postoperative day 15 without any post‑operative complications. No signs of recurrence were observed during a 22‑month follow‑up. In the setting of rectal cancer‑induced FGs, the liquid resuscitation, broad‑spectrum antibiotic therapy, and prompt debridement are the cornerstones of the initial management. Diversional colostomy and VAC therapy were effective in the management of severe infection and large wounds. The present case report also provided a clinical reference for the implementation of staged surgeries and the perioperative multidisciplinary management of FGs.
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April-2024
Volume 20 Issue 4

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Spandidos Publications style
Hou S, Cheng B, Shen K, Gao Z, Liu F and Ye Y: Fournier's gangrene due to rectal cancer: A case report. Mol Clin Oncol 20: 30, 2024
APA
Hou, S., Cheng, B., Shen, K., Gao, Z., Liu, F., & Ye, Y. (2024). Fournier's gangrene due to rectal cancer: A case report. Molecular and Clinical Oncology, 20, 30. https://doi.org/10.3892/mco.2024.2728
MLA
Hou, S., Cheng, B., Shen, K., Gao, Z., Liu, F., Ye, Y."Fournier's gangrene due to rectal cancer: A case report". Molecular and Clinical Oncology 20.4 (2024): 30.
Chicago
Hou, S., Cheng, B., Shen, K., Gao, Z., Liu, F., Ye, Y."Fournier's gangrene due to rectal cancer: A case report". Molecular and Clinical Oncology 20, no. 4 (2024): 30. https://doi.org/10.3892/mco.2024.2728