1
|
Rosenblum WD: Pulmonary arterial
hypertension: Pathobiology, diagnosis, treatment, and emerging
therapies. Cardiol Rev. 18:58–63. 2010. View Article : Google Scholar : PubMed/NCBI
|
2
|
Pak O, Aldashev A, Welsh D and Peacock A:
The effects of hypoxia on the cells of the pulmonary vasculature.
Eur Respir J. 30:364–372. 2007. View Article : Google Scholar : PubMed/NCBI
|
3
|
Sommer N, Dietrich A, Schermuly RT,
Ghofrani HA, Gudermann T, Schulz R, Seeger W, Grimminger F and
Weissmann N: Regulation of hypoxic pulmonary vasoconstriction:
Basic mechanisms. Eur Respir J. 32:1639–1651. 2008. View Article : Google Scholar : PubMed/NCBI
|
4
|
Sarkar J, Gou D, Turaka P, Viktorova E,
Ramchandran R and Raj JU: MicroRNA-21 plays a role in
hypoxia-mediated pulmonary artery smooth muscle cell proliferation
and migration. Am J Physiol Lung Cell Mol Physiol. 299:L861–L871.
2010. View Article : Google Scholar : PubMed/NCBI
|
5
|
Cha ST, Chen PS, Johansson G, Chu CY, Wang
MY, Jeng YM, Yu SL, Chen JS, Chang KJ, Jee SH, et al: MicroRNA-519c
suppresses hypoxia-inducible factor-1alpha expression and tumor
angiogenesis. Cancer Res. 70:2675–2685. 2010. View Article : Google Scholar : PubMed/NCBI
|
6
|
Jiang Y, Yin H and Zheng XL: MicroRNA-1
inhibits myocardin-induced contractility of human vascular smooth
muscle cells. J Cell Physiol. 225:506–511. 2010. View Article : Google Scholar : PubMed/NCBI
|
7
|
Guo L, Qiu Z, Wei L, Yu X, Gao X, Jiang S,
Tian H, Jiang C and Zhu D: The microRNA-328 regulates hypoxic
pulmonary hypertension by targeting at insulin growth factor 1
receptor and L-type calcium channel-α1C. Hypertension.
59:1006–1013. 2012. View Article : Google Scholar : PubMed/NCBI
|
8
|
Courboulin A, Paulin R, Giguère NJ,
Saksouk N, Perreault T, Meloche J, Paquet ER, Biardel S, Provencher
S, Côté J, et al: Role for miR-204 in human pulmonary arterial
hypertension. J Exp Med. 208:535–548. 2011. View Article : Google Scholar : PubMed/NCBI
|
9
|
Li S, Ran Y, Zhang D, Chen J, Li S and Zhu
D: MicroRNA-138 plays a role in hypoxic pulmonary vascular
remodelling by targeting Mst1. Biochem J. 452:281–291. 2013.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Brock M, Samillan VJ, Trenkmann M,
Schwarzwald C, Ulrich S, Gay RE, Gassmann M, Ostergaard L, Gay S,
Speich R and Huber LC: AntagomiR directed against miR-20a restores
functional BMPR2 signalling and prevents vascular remodelling in
hypoxia-induced pulmonary hypertension. Eur Heart J. 35:3203–3211.
2014. View Article : Google Scholar : PubMed/NCBI
|
11
|
Caruso P, Dempsie Y, Stevens HC, McDonald
RA, Long L, Lu R, White K, Mair KM, McClure JD, Southwood M, et al:
A role for miR-145 in pulmonary arterial hypertension: Evidence
from mouse models and patient samples. Circ Res. 111:290–300. 2012.
View Article : Google Scholar : PubMed/NCBI
|
12
|
Li SS, Ran YJ, Zhang DD, Li SZ and Zhu D:
MicroRNA-190 regulates hypoxic pulmonary vasoconstriction by
targeting a voltage-gated K+ channel in arterial smooth muscle
cells. J Cell Biochem. 115:1196–1205. 2014. View Article : Google Scholar : PubMed/NCBI
|
13
|
He S, Liu P, Jian Z, Li J, Zhu Y, Feng Z
and Xiao Y: miR-138 protects cardiomyocytes from hypoxia-induced
apoptosis via MLK3/JNK/c-jun pathway. Biochem Biophys Res Commun.
441:763–769. 2013. View Article : Google Scholar : PubMed/NCBI
|
14
|
Li GW, Xing WJ, Bai SZ, Hao JH, Guo J, Li
HZ, Li HX, Zhang WH, Yang BF, Wu LY, et al: The calcium-sensing
receptor mediates hypoxia-induced proliferation of rat pulmonary
artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways.
Basic Clin Pharmacol Toxicol. 108:185–193. 2011. View Article : Google Scholar : PubMed/NCBI
|
15
|
Olschewski A, Li Y, Tang B, Hanze J, Eul
B, Bohle RM, Wilhelm J, Morty RE, Brau ME, Weir EK, et al: Impact
of TASK-1 in human pulmonary artery smooth muscle cells. Circ Res.
98:1072–1080. 2006. View Article : Google Scholar : PubMed/NCBI
|
16
|
Bryan RM Jr, You J, Phillips SC, Andresen
JJ, Lloyd EE, Rogers PA, Dryer SE and Marrelli SP: Evidence for
two-pore domain potassium channels in rat cerebral arteries. Am J
Physiol Heart Circ Physiol. 291:H770–H780. 2006. View Article : Google Scholar : PubMed/NCBI
|
17
|
Davie N, Haleen SJ, Upton PD, Polak JM,
Yacoub MH, Morrell NW and Wharton J: ET(A) and ET(B) receptors
modulate the proliferation of human pulmonary artery smooth muscle
cells. Am J Respir Crit Care Med. 165:398–405. 2002. View Article : Google Scholar : PubMed/NCBI
|
18
|
Zhang XF, Zhu J, Geng WY, Zhao SJ, Jiang
CW, Cai SR, Cheng M, Zhou CY and Liu ZB: Electroacupuncture at
Feishu (BL13) and Zusanli (ST36) down-regulates the expression of
orexins and their receptors in rats with chronic obstructive
pulmonary disease. J Integr Med. 12:417–424. 2014. View Article : Google Scholar : PubMed/NCBI
|
19
|
Liu X, Jiang L, Wang A, Yu J, Shi F and
Zhou X: MicroRNA-138 suppresses invasion and promotes apoptosis in
head and neck squamous cell carcinoma cell lines. Cancer Lett.
286:217–222. 2009. View Article : Google Scholar : PubMed/NCBI
|
20
|
Zhang YH, Wang Y, Yusufali AH, Ashby F,
Zhang D, Yin ZF, Aslanidi GV, Srivastava A, Ling CQ and Ling C:
Cytotoxic genes from traditional Chinese medicine inhibit tumor
growth both in vitro and in vivo. J Integr Med.
12:483–494. 2014. View Article : Google Scholar : PubMed/NCBI
|
21
|
Perelman A, Wachtel C, Cohen M, Haupt S,
Shapiro H and Tzur A: JC-1: Alternative excitation wavelengths
facilitate mitochondrial membrane potential cytometry. Cell Death
Dis. 3:e4302012. View Article : Google Scholar : PubMed/NCBI
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Lewis BP, Burge CB and Bartel DP:
Conserved seed pairing, often flanked by adenosines, indicates that
thousands of human genes are microRNA targets. Cell. 120:15–20.
2005. View Article : Google Scholar : PubMed/NCBI
|
24
|
Corsten MF, Dennert R, Jochems S,
Kuznetsova T, Devaux Y, Hofstra L, Wagner DR, Staessen JA, Heymans
S and Schroen B: Circulating microRNA-208b and microRNA-499 reflect
myocardial damage in cardiovascular disease. Circ Cardiovasc Genet.
3:499–506. 2010. View Article : Google Scholar : PubMed/NCBI
|
25
|
Kim J, Kang Y, Kojima Y, Lighthouse JK, Hu
X, Aldred MA, McLean DL, Park H, Comhair SA, Greif DM, et al: An
endothelial apelin-FGF link mediated by miR-424 and miR-503 is
disrupted in pulmonary arterial hypertension. Nat Med. 19:74–82.
2013. View
Article : Google Scholar : PubMed/NCBI
|
26
|
Gou D, Ramchandran R, Peng X, Yao L, Kang
K, Sarkar J, Wang Z, Zhou G and Raj JU: miR-210 has an
antiapoptotic effect in pulmonary artery smooth muscle cells during
hypoxia. Am J Physiol Lung Cell Mol Physiol. 303:L682–L691. 2012.
View Article : Google Scholar : PubMed/NCBI
|
27
|
Li SS, Ran YJ, Zhang DD, Li SZ and Zhu D:
MicroRNA-190 regulates hypoxic pulmonary vasoconstriction by
targeting a voltage-gated K+ channel in arterial smooth muscle
cells. J Cell Biochem. 115:1196–1205. 2014. View Article : Google Scholar : PubMed/NCBI
|
28
|
Yang S, Banerjee S, De Freitas Ad, Cui H,
Xie N, Abraham E and Liu G: miR-21 regulates chronic
hypoxia-induced pulmonary vascular remodeling. Am J Physiol Lung
Cell Mol Physiol. 302:L521–L529. 2012. View Article : Google Scholar : PubMed/NCBI
|
29
|
Xu J, Li L, Yun HF and Han YS: MiR-138
promotes smooth muscle cells proliferation and migration in db/db
mice through down-regulation of SIRT1. Biochem Biophys Res Commun.
463:1159–1164. 2015. View Article : Google Scholar : PubMed/NCBI
|
30
|
Takahashi A, Masuda A, Sun M, Centonze VE
and Herman B: Oxidative stress-induced apoptosis is associated with
alterations in mitochondrial caspase activity and Bcl-2-dependent
alterations in mitochondrial pH (pHm). Brain Res Bull. 62:497–504.
2004. View Article : Google Scholar : PubMed/NCBI
|
31
|
Patel AJ and Lazdunski M: The 2P-domain K+
channels: Role in apoptosis and tumorigenesis. Pflugers Arch.
448:261–273. 2004. View Article : Google Scholar : PubMed/NCBI
|