Open Access

Immunotherapy in combination with neoadjuvant anthracycline‑free chemotherapy for triple‑negative early breast cancer: A case report

  • Authors:
    • Xiangwang Zhao
    • Fang Dong
    • Weibin Chen
    • Chunping Liu
  • View Affiliations

  • Published online on: July 17, 2023     https://doi.org/10.3892/ol.2023.13961
  • Article Number: 374
  • Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Immunotherapy is a promising anticancer strategy. In the present report, the case of a 36‑year‑old female patient with pathologically diagnosed, left triple‑negative breast cancer and axillary lymph node involvement is reported. The patient received immunotherapy in combination with neoadjuvant anthracycline‑free chemotherapy for six cycles, before undergoing left mastectomy and left axillary lymph node dissection. The postoperative pathology was a complete response to treatment, involving eradication of tumor from both the breast and the relevant lymph nodes. However, thyroid dysfunction occurred after two cycles of neoadjuvant treatment. The clinical presentation of the thyroid disorder was transient hyperthyroidism for 4 weeks and subsequent hypothyroidism, which required hormone replacement therapy.
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September-2023
Volume 26 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Zhao X, Dong F, Chen W and Liu C: Immunotherapy in combination with neoadjuvant anthracycline‑free chemotherapy for triple‑negative early breast cancer: A case report. Oncol Lett 26: 374, 2023
APA
Zhao, X., Dong, F., Chen, W., & Liu, C. (2023). Immunotherapy in combination with neoadjuvant anthracycline‑free chemotherapy for triple‑negative early breast cancer: A case report. Oncology Letters, 26, 374. https://doi.org/10.3892/ol.2023.13961
MLA
Zhao, X., Dong, F., Chen, W., Liu, C."Immunotherapy in combination with neoadjuvant anthracycline‑free chemotherapy for triple‑negative early breast cancer: A case report". Oncology Letters 26.3 (2023): 374.
Chicago
Zhao, X., Dong, F., Chen, W., Liu, C."Immunotherapy in combination with neoadjuvant anthracycline‑free chemotherapy for triple‑negative early breast cancer: A case report". Oncology Letters 26, no. 3 (2023): 374. https://doi.org/10.3892/ol.2023.13961