Open Access

Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review

  • Authors:
    • Denghao Yang
    • Wen Tang
    • Mingwen Liu
    • Zhifei Xie
    • Fei Shi
    • Zeju Zhao
    • Xiaorong Yang
    • Tao Wu
  • View Affiliations

  • Published online on: November 21, 2023     https://doi.org/10.3892/ol.2023.14162
  • Article Number: 29
  • Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Renal cell carcinoma (RCC) associated with Xp11.2 translocation/transcription factor E3 (TFE3) gene fusion is a rare subtype of RCC. A 31‑year‑old male patient was admitted to The Affiliated Hospital of Zunyi Medical University (Zunyi, China) with a solid mass in the left kidney during a routine health examination. After ruling out surgical contraindications, the patient underwent a laparoscopic left partial nephrectomy under general anesthesia. Postoperative pathology and fluorescence in situ hybridization (FISH) identified Xp11.2 translocation RCC. There was no tumor recurrence or metastasis during the 1‑year follow‑up. Xp11.2 translocation RCC is unusual, its clinical and imaging findings are not specific, and the diagnosis depends on TFE3‑immunohistochemical assay and FISH analysis. Surgical resection is the first choice of treatment and its prognosis is worse than that of clear cell RCC, thus regular follow‑ups are necessary.
View Figures
View References

Related Articles

Journal Cover

January-2024
Volume 27 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Yang D, Tang W, Liu M, Xie Z, Shi F, Zhao Z, Yang X and Wu T: Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review. Oncol Lett 27: 29, 2024
APA
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z. ... Wu, T. (2024). Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review. Oncology Letters, 27, 29. https://doi.org/10.3892/ol.2023.14162
MLA
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z., Yang, X., Wu, T."Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review". Oncology Letters 27.1 (2024): 29.
Chicago
Yang, D., Tang, W., Liu, M., Xie, Z., Shi, F., Zhao, Z., Yang, X., Wu, T."Renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion: A case report and literature review". Oncology Letters 27, no. 1 (2024): 29. https://doi.org/10.3892/ol.2023.14162