Atypical meningioma with destruction of cervical vertebrae inside the spinal canal: A case report and literature review

Mu,Likun; Wang,Mingxin; Cheng,Lifeng; Chu,Guangxu; Song,Zuyao

doi:10.3892/ol.2023.14178

Atypical meningioma with destruction of cervical vertebrae inside the spinal canal: A case report and literature review

Authors:
- Likun Mu
- Mingxin Wang
- Lifeng Cheng
- Guangxu Chu
- Zuyao Song
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Affiliations: Department of Neurosurgery, Shengli Oilfield Center Hospital, Dongying, Shandong 257099, P.R. China
Published online on: December 6, 2023 https://doi.org/10.3892/ol.2023.14178
Article Number: 45

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Abstract

Atypical meningioma is a specific type of meningioma that is relatively rare in clinical practice. The clinical manifestations of atypical meningioma are non‑specific and the imaging findings are similar to those for other intraspinal space‑occupying lesions. It is usually misdiagnosed as schwannoma or metastases, and it is necessary to rely on intraoperative findings and pathological examination to confirm the diagnosis. Atypical meningioma invading the intervertebral foramen and causing bone destruction is rare. The present study describes the case of a patient with cervical intraspinal atypical meningioma combined with cervical bone destruction. A 50‑year‑old female patient presented with numbness of the extremities with unstable walking, and underwent magnetic resonance imaging (MRI) of the cervical spine. MRI showed a space‑occupying lesion in the spinal canal at the C2‑4 level. The patient underwent cervical intraspinal lesion resection, and postoperative pathology confirmed atypical meningioma (World Health Organization grade II). The patient received dehydration and hormone therapy, and was discharged after the symptoms improved. Radiotherapy was performed 2 months after discharge. Cervical MRI 3 months after the operation showed that the tumor resection was satisfactory. To the best of our knowledge, the present study is the first to report on this specific type of meningioma. The present case report may provide useful information for clinicians to diagnose and treat the disease.

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