Open Access

Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review)

  • Authors:
    • Yongmin Liu
    • Guanchu Li
    • Jinyue Ning
    • Yi Zhao
  • View Affiliations

  • Published online on: February 28, 2024     https://doi.org/10.3892/ol.2024.14315
  • Article Number: 182
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Ginsenoside Rg3 (GS‑Rg3), a sterol molecule isolated from ginseng, has demonstrated various immunological properties, including inhibition of cancer cell proliferation and metastasis, reversal of drug resistance and enhancement of chemotherapy sensitivity. The recent surge in attention towards GS‑Rg3 can be attributed to its potential as an antitumor angiogenesis agent and as a therapeutic candidate for immunotherapy. The development of GS‑Rg3 as an agent for these purposes has accelerated research on its mechanisms of action. The present review summarizes recent studies investigating the antitumor activity of GS‑Rg3 and its underlying mechanisms, as well as providing essential information for future studies on GS‑Rg3.
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April-2024
Volume 27 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Liu Y, Li G, Ning J and Zhao Y: Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review). Oncol Lett 27: 182, 2024
APA
Liu, Y., Li, G., Ning, J., & Zhao, Y. (2024). Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review). Oncology Letters, 27, 182. https://doi.org/10.3892/ol.2024.14315
MLA
Liu, Y., Li, G., Ning, J., Zhao, Y."Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review)". Oncology Letters 27.4 (2024): 182.
Chicago
Liu, Y., Li, G., Ning, J., Zhao, Y."Unveiling the experimental proof of the anticancer potential of ginsenoside Rg3 (Review)". Oncology Letters 27, no. 4 (2024): 182. https://doi.org/10.3892/ol.2024.14315