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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-June 2011 Volume 2 Issue 3

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Impact Factor: 2.3

Review

‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype (Review)

Pascale Quatresooz, Marie-Annick Reginster, Gérald E. Piérard
Pages: 379-384
Published online on: 28 February 2011

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Review

Detection of circulating tumor cells: Clinical relevance of a novel metastatic tumor marker (Review)

Chuanli Ren, Chongxu Han, Daxin Wang, Xiaohang Zhao, Guangfu Jin, Hongbing Shen
Pages: 385-391
Published online on: 21 March 2011

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Article Open Access

Trifluorothymidine exhibits potent antitumor activity via the induction of DNA double-strand breaks

Norihiko Suzuki, Fumio Nakagawa, Mamoru Nukatsuka, Masakazu Fukushima
Pages: 393-397
Published online on: 21 March 2011

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Article

Use of protein array technology to investigate receptor tyrosine kinases activated in hepatocellular carcinoma

Shi Liu, Jian Gong, Asahiro Morishita, Takako Nomura, Hisaaki Miyoshi, Joji Tani, Kiyohito Kato, Hirohito Yoneyama, Akihiro Deguchi, Hirohito Mori, Shima Mimura, Kei Nomura, Takashi Himoto, Kazushi Deguchi, Keiichi Okano, Kunihiko Izuishi, Yasuyuki Suzuki, Yoshio Kushida, Reiji Haba, Hisakazu Iwama, Tsutomu Masaki
Pages: 399-403
Published online on: 08 February 2011

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Article

Activin A maintains pluripotency markers and proliferative potential of human induced pluripotent stem cells

Minoru Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshida
Pages: 405-408
Published online on: 28 February 2011

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Article

Feasibility of large-scale screening using N-ERC/mesothelin levels in the blood for the early diagnosis of malignant mesothelioma

Kohta Imashimizu, Kazu Shiomi, Masahiro Maeda, Naoko Aoki, Kiyoko Igarashi, Fumio Suzuki, Mitsuru Koizumi, Kenji Suzuki, Okio Hino
Pages: 409-411
Published online on: 08 March 2011

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Article

Rosiglitazone and retinoic acid inhibit proliferation and induce apoptosis in the HCT-15 human colorectal cancer cell line

Ruizheng Miao, Tao Xu, Liqing Liu, Meng Wang, Yanming Jiang, Jianfeng Li, Renle Guo
Pages: 413-417
Published online on: 10 March 2011

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Article

Vitamin B6 regulates mRNA expression of peroxisome proliferator-activated receptor-γ target genes

Noriyuki Yanaka, Mayumi Kanda, Keigo Toya, Haruna Suehiro, Norihisa Kato
Pages: 419-424
Published online on: 21 March 2011

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Article

High TSC22D3 and low GBP1 expression in the liver is a risk factor for early recurrence of hepatocellular carcinoma

Keiko Takagi, Tadatoshi Takayama, Hiroki Nagase, Masamichi Moriguchi, Xiaofei Wang, Kaname Hirayanagi, Tsukasa Suzuki, Hiromasa Hasegawa, Takanaga Ochiai, Nobuhisa Yamaguchi, Mitsugu Kochi, Makoto Kimura, Mariko Esumi
Pages: 425-431
Published online on: 21 March 2011

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Article

Sorafenib and hepatic arterial infusion chemotherapy for unresectable advanced hepatocellular carcinoma: A comparative study

Yasunari Hiramine, Hirofumi Uto, Yasushi Imamura, Kazuaki Tabu, Yoshirou Baba, Takuya Hiwaki, Yukihiko Sho, Kenji Tahara, Hirofumi Higashi, Tutomu Tamai, Makoto Oketani, Akio Ido, Hirohito Tsubouchi
Pages: 433-441
Published online on: 21 March 2011

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Article Open Access

Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit

Eui Young So, Toru Ouchi
Pages: 443-447
Published online on: 21 March 2011

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Article

Addition of erlotinib to fluoropyrimidine-oxaliplatin-based chemotherapy with or without bevacizumab: Two sequential phase I trials

Chiara Carlomagno, Gennaro Daniele, Roberto Bianco, Roberta Marciano, Vincenzo Damiano, Elide Matano, Lucia Nappi, Stefano Pepe, Sabino De Placido, Giampaolo Tortora
Pages: 449-455
Published online on: 25 February 2011

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Article

Tyrosine phosphatase PTPRD suppresses colon cancer cell migration in coordination with CD44

Kosuke Funato, Yusuke Yamazumi, Takeaki Oda, Tetsu Akiyama
Pages: 457-463
Published online on: 21 March 2011

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Article

Cancer stem cell-related factors are associated with the efficacy of pre-operative chemoradiotherapy for locally advanced rectal cancer

Kazuaki Hiroishi, Masafumi Inomata, Kenji Kashima, Kazuhiro Yasuda, Norio Shiraishi, Shigeo Yokoyama, Seigo Kitano
Pages: 465-470
Published online on: 21 March 2011

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Article

Nuclear expression of N-myc downstream regulated gene 1/Ca2+-associated protein 43 is closely correlated with tumor angiogenesis and poor survival in patients with gastric cancer

Akihiko Kawahara, Jun Akiba, Satoshi Hattori, Tomohiko Yamaguchi, Hideyuki Abe, Tomoki Taira, Hiroki Ureshino, Yuichi Murakami, Kosuke Watari, Kikuo Koufuji, Kazuo Shirouzu, Michihiko Kuwano, Mayumi Ono, Masayoshi Kage
Pages: 471-479
Published online on: 02 March 2011

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Article

Arsenic trioxide induces the apoptosis of human breast cancer MCF-7 cells through activation of caspase-3 and inhibition of HERG channels

Ying Wang, Yong Zhang, Lei Yang, Benzhi Cai, Jianping Li, You Zhou, Li Yin, Lili Yang, Baofeng Yang, Yanjie Lu
Pages: 481-486
Published online on: 08 March 2011

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Article

Expression profile of HMBOX1, a novel transcription factor, in human cancers using highly specific monoclonal antibodies

Jun Dai, Cai Zhang, Zhigang Tian, Jian Zhang
Pages: 487-490
Published online on: 21 March 2011

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Article

Retinoid acid receptors in human colorectal cancer: An unexpected link with patient outcome

Aurélie Perraud, Michelle Nouaille, Hussein Akil, Daniel Petit, François Labrousse, Marie-Odile Jauberteau, Muriel Mathonnet
Pages: 491-497
Published online on: 21 March 2011

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Article

Evaluation of the combined expression of chemokine SDF-1α and its receptor CXCR4 as a prognostic marker for gastric cancer

Hyo Jin Lee, Song Mei Huang, Ha Yon Kim, Yoon Suk Oh, Ji Young Hwang, Zhe Long Liang, Jeong Ki Min, Hwan Jung Yun, Ji Young Sul, Samyong Kim, Deog Yeon Jo, Jin Man Kim
Pages: 499-504
Published online on: 16 March 2011

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Article

Overexpression of engulfment and cell motility 1 promotes cell invasion and migration of hepatocellular carcinoma

JiaRui Jiang, GuoQing Liu, XiongYing Miao, SongWen Hua, DeWu Zhong
Pages: 505-511
Published online on: 18 March 2011

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Article

Effect of high hydrostatic pressure on the expression of glutamine synthetase in rat retinal Müller cells cultured in vitro

Jun Yu, Yisheng Zhong, Yu Cheng, Xi Shen, Jun Wang, Yiyong Wei
Pages: 513-516
Published online on: 21 March 2011

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Article

Significance of CXCR4, phosphorylated STAT3 and VEGF-A expression in resected non-small cell lung cancer

Meng Wang, Gong-Yan Chen, Hong-Tao Song, Xuan Hong, Zhao-Yang Yang, Guang-Jie Sui
Pages: 517-522
Published online on: 21 March 2011

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Article

Imaging agents for in vivo molecular profiling of disseminated prostate cancer: Cellular processing of [111In]-labeled CHX-A''DTPA-trastuzumab and anti-HER2 ABY-025 Affibody in prostate cancer cell lines

Jennie Malmberg, Vladimir Tolmachev, Anna Orlova
Pages: 523-528
Published online on: 22 February 2011

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Article

Thalidomide and irradiation combination therapy increases substance P levels in vitro

Ece Şimşek Oz, Esra Aydemir, Aylin Fidan Korcum, Kayahan Fıskın
Pages: 529-535
Published online on: 14 February 2011

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Article

Analysis of estrogen receptor isoforms and variants in breast cancer cell lines

Maie Al-Bader, Christopher Ford, Bushra Al-Ayadhy, Issam Francis
Pages: 537-544
Published online on: 10 March 2011

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Article

Anti-inflammatory effect of patchouli alcohol isolated from Pogostemonis Herba in LPS-stimulated RAW264.7 macrophages

Yan-Fang Xian, Yu-Cui Li, Siu-Po Ip, Zhi-Xiu Lin, Xiao-Ping Lai, Zi-Ren Su
Pages: 545-550
Published online on: 21 March 2011

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Article

A primary experience of conventional fractionated three-dimensional conformal partial breast irradiation for early-stage breast cancer

LingXia Liao, Guang Han, YanPing Li, ZhaoHua Wang, Dong Liu, ZhengChao Pi
Pages: 551-555
Published online on: 02 March 2011

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Article

Antitumor effects of imatinib mesylate and synergistic cytotoxicity with an arsenic compound in neuroblastoma cell lines

Kyung-Jin Kim, Jung-Moon Jung, Jung-Youn Cho, So-Youn Woo, Kyung-Ah Cho, Kyung-Ha Ryu, Eun-Sun Yoo
Pages: 557-561
Published online on: 28 February 2011

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Article

Association of dynamic changes in serum cytokine levels with the severity of injury in patients suffering from closed chest traumas complicated with pulmonary contusions

Keqiang Liu, Jifu Liu, Shanshan Wu
Pages: 563-567
Published online on: 21 March 2011

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Case Report

Pulmonary alveolar proteinosis and successful therapy with combined lavage procedures: Case reports

Nalan Demir Firat, Aydin Ciledag, Pinar Akin Kabalak, Demet Karnak, Basak Ceyda Meco, Zekeriyya Alanoglu, Neslihan Alkis
Pages: 569-573
Published online on: 18 March 2011

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Journal Cover
July-2026 Volume 32 Issue 1

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Impact Factor: 2.3

Article Open Access

Amplification of heterogeneous nuclear ribonucleoprotein A/B aids in immune infiltration regulation and breast cancer tumorigenesis

Jiachao Xu, Qian Han, Libin Chen, Min Yang, Jun Huang, Shanhong Lin, Shengmin Zhang
Article Number: 198
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] Novel triazole analogs of apigenin‑7‑methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial‑mediated apoptosis

Yuyan Qi, Zhaoxia Ding, Yushuang Yao, Dehua Ma, Feifei Ren, Hongjuan Yang, Aiping Chen
Article Number: 197
Published online on: 26 May 2026

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Article Open Access

Meta‑analysis of the efficacy of reverse total shoulder arthroplasty and open reduction and internal fixation in the treatment of proximal humerus fractures

Yuan Li, Meng-Xuan Niu, Fang-Zheng He, Xin Qin, Wei-Wei Wang, Peng-Fei Han
Article Number: 196
Published online on: 21 May 2026

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Article Open Access

Fatty acid‑activated proton transporter SR4 prevents hepatic steatosis and metabolic alterations in diabetic mice by improving mitochondria function, energy balance and oxidative stress

James Figarola, Jyotsana Singhal, Sharad Singhal
Article Number: 195
Published online on: 20 May 2026

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Expression of Concern Open Access

[Expression of Concern] Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory‑fibrosis through the NF‑κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory‑fibrosis by inhibiting endogenous Nampt

Ye Chen, Yuzhen Liang, Tingting Hu, Riming Wei, Congjie Cai, Ping Wang, Lingyu Wang, Wei Qiao, Leping Feng
Article Number: 194
Published online on: 20 May 2026

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Article Open Access

Impact of vitamin D receptor gene variants on psoriasis vulgaris susceptibility and clinical phenotype in a Greek population

Polytimi Sidiropoulou, Martha Katsarou, Maria Papasavva, Annia Tsolakou, Akylas Fotiadis, Demetrios A. Spandidos, Natalia Rompoti, Irene Stefanaki, Alexander J. Stratigos, Nikolaos Drakoulis, Electra Nicolaidou
Article Number: 193
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Resistin increases the expression of NOD2 in mouse monocytes

Yi Ren, Taomei Wan, Zhicai Zuo, Hengmin Cui, Xi Peng, Jing Fang, Junliang Deng, Yanchun Hu, Shuming Yu, Liuhong Shen, Xiaoping Ma, Ya Wang, Zhihua Ren
Article Number: 192
Published online on: 18 May 2026

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Case Report Open Access

Morphological analysis of bronchoalveolar lavage fluid in diagnosing pulmonary aspergilloma in a patient with rheumatoid arthritis: A case report

Yuli Zhou, Yuyi Lai, Fuxian Zhou, Xinxin Wang, Xiao He, Juan Jin, Ruikai Zhang
Article Number: 191
Published online on: 14 May 2026

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Case Report Open Access

Intravenous leiomyomatosis of the uterus: A case report and literature review

Yuzhen Zhao, Fei Tian
Article Number: 190
Published online on: 14 May 2026

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Case Report Open Access

3D‑Printed prosthesis for recurrent femoral metastasis with periprosthetic infection: A case report

Jiangbi Li, Yangjie Zhang, Jianping Kang, Changping Tian, Suolin Chen, Ya Ning, Haixia Li, Yanbin Xiao
Article Number: 189
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Targeting Sirt1 in a rat model of high‑fat diet‑induced non‑alcoholic fatty liver disease: Comparison of Gegen Qinlian decoction and resveratrol

Yi Guo, Jun-Xiang Li, Tang-You Mao, Wei-Han Zhao, Li-Juan Liu, Yun-Liang Wang
Article Number: 188
Published online on: 13 May 2026

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Article Open Access

Glycolytic reprogramming in host response to Borrelia burgdorferi: A gene signature revealed by integrative bioinformatics analysis and machine learning

Yan Dong, Yantong Chen, Yanshuang Luo, Meng Liu, Chao Song, Xuesong Chen, Fusong Yang, Qingyi Luo, Guozhong Zhou
Article Number: 187
Published online on: 12 May 2026

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Retraction Open Access

[Retracted]Oblongifolin C reverses GEM resistance via suppressing autophagy flux in bladder cancer cells

Zhilong Huang, Tingting Wang, Wenjun Xia, Qing Li, Xinlei Chen, Xiaoli Liu, Peng Wei, Wenping Xu, Meirong Lv
Article Number: 186
Published online on: 11 May 2026

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Article Open Access

Genetic etiology and phenotypic characteristics of fetuses with 11q deletion syndrome (11q23.3‑q25)

Tong Zhang, Xiaoyi Cong, Zhenming Li, Xianzhen Cao, Liang Hu, Xiaojin Luo, Yanan Liu, Weiqiang Liu, Fengxiang Wei
Article Number: 185
Published online on: 08 May 2026

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Article Open Access

CDX2‑UPK1B‑PIK3IP1‑PI3K/AKT signaling axis regulates gastric cancer cell invasion and migration and influences patient prognosis

Shaodong Zhong, Heng Zhang, Jin Huang
Article Number: 184
Published online on: 08 May 2026

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Review Open Access

Modulation of the tumor microenvironment by incretins and glucagon: Metabolic and immune mechanisms (Review)

Min Hu, Chang-Jun Jiang, Cheng Yi
Article Number: 183
Published online on: 08 May 2026

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Article Open Access

TPX2 as a prognostic biomarker and potential therapeutic target for malignant melanoma proliferation and metastasis

Fuqi Li, Ronghui Yang, Zhixian Wu
Article Number: 182
Published online on: 08 May 2026

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Review Open Access

Benefits and mechanisms of polysaccharides derived from traditional Chinese medicine for ulcerative colitis treatment (Review)

Yuebo Jia, Zheng Jiao, Lingshuo Bai, Gege Li, Lijian Pang
Article Number: 181
Published online on: 08 May 2026

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Retraction Open Access

[Retracted] Synergistic inhibition of leukemia WEHI‑3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo

Yu-Jui Kuo, Yan-Jin Liu, Tzong-Der Way, Su-Yin Chiang, Jaung-Geng Lin, Jing-Gung Chung
Article Number: 180
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 32 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Immune‑related nephritis, ureteritis and cystitis secondary to immune checkpoint inhibitors: A case report and review of the literature

Guangquan Zhang, Silu Xu, Jing Wu, Qianqian Gao, Yanzhi Bi, Min Xiao
Article Number: 210
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro

Biao Luo, Fei Liao, Yanchun Hu, Xi Liu, Yajun He, Lei Wu, Hui Tan, Lijuan Luo, Yancheng Zhou, Quan Mo, Junliang Deng, Yahui Wei
Article Number: 209
Published online on: 08 June 2026

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Case Report Open Access

Epithelioid fibrous histiocytoma of eyelid in children: A case report

Zheng Sun, Zhaoxia Zhai, Yutian Li, Peiyan Shi, Wei Cheng, Jinling Ge, Yanfei Li
Article Number: 208
Published online on: 05 June 2026

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Article

Stevens‑Johnson syndrome induced by fluoroquinolones in a patient with colon cancer: A case report and literature review

Yuan Zhou, Guangye Huang, Hongxia Li
Article Number: 207
Published online on: 04 June 2026

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Article Open Access

Sotagliflozin ameliorates doxorubicin-induced cardiomyopathy by regulating inflammation and mitochondrial dysfunction through the AMPK/mTOR pathway

Haifeng Liu, Danye Han, Meiling Li
Article Number: 206
Published online on: 04 June 2026

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Article Open Access

Integrated network pharmacology and serum metabolomics to reveal the protective mechanism of methanolic extract of BaiYangJie on cisplatin‑induced acute kidney injury in mice

Bin Xia, Jianglong Chen, Jinhui Wang, Dalong Li, Lixia Zhang, Jing Su, Xuan Ding, Yana Lv, Shifang Liu, Xue Zhang, Tianzhen Wan, Guang Li
Article Number: 205
Published online on: 04 June 2026

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Article Open Access

Screening criteria for drainage-free patients after retroperitoneal laparoscopic adrenal tumor resection and their prospective validation study value

Yan Zhao, Yu-Xuan He, Hai-Tao Li, Jing-Yi Cao, Bing Zhong, Hui Zhou
Article Number: 204
Published online on: 04 June 2026

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Retraction Open Access

[Retracted] Atorvastatin increases lipopolysaccharide‑induced expression of tumour necrosis factor‑α‑induced protein 8‑like 2 in RAW264.7 cells

Ming-Wei Liu, Mei-Xian Su, Wei Zhang, Li Wang, Chuan-Yun Qian
Article Number: 203
Published online on: 02 June 2026

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Case Report Open Access

LMNA c.1622G>A mutation and myopathic changes in a family with limb‑girdle muscular dystrophy: A case report

Yanling Zhu, Qiushi Wang, Tiefeng Zhang
Article Number: 202
Published online on: 02 June 2026

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Case Report Open Access

Optimizing management of immune checkpoint inhibitor‑induced inflammatory arthritis: A case series and literature review

Yuanyuan Wang, Yingmei Wen, Jinxiong Xia, Hongyan Feng, Fei Wu, Dafu Ye, Yanjun Gao, Qingqing Li, Yi Yao
Article Number: 201
Published online on: 29 May 2026

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Article Open Access

Tumor Treating Fields modulate apoptotic and immune programs in T‑cell acute lymphoblastic leukemia cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 200
Published online on: 29 May 2026

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Case Report

Complete ureteral duplication with occult calculi: A case report

Haiyan Zheng, Li Wang, Rui Yang, Shenghao Niu, Faying Yang, Jiaxi Yao
Article Number: 199
Published online on: 29 May 2026

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