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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2008 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Aberrant NF-κB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor

Tong-Xin Xie, Kenneth D. Aldape, Weida Gong, Takao Kanzawa, Dima Suki, Seiji Kondo, Frederick Lang, Francis Ali-Osman, Raymond Sawaya, Suyun Huang
Pages: 5-15
Published online on: 01 July 2008

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Article

Cadherin-11-mediated interactions with bone marrow stromal/osteoblastic cells support selective colonization of breast cancer cells in bone

Daisuke Tamura, Toru Hiraga, Akira Myoui, Hideki Yoshikawa, Toshiyuki Yoneda
Pages: 17-24
Published online on: 01 July 2008

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Article

Silencing of LRRC49 and THAP10 genes by bidirectional promoter hypermethylation is a frequent event in breast cancer

Emerson De Souza Santos, Simone A. De Bessa, Mario M. Netto, Maria A. Nagai
Pages: 25-31
Published online on: 01 July 2008

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Article

Tum-1, a tumstatin fragment, gene delivery into hepatocellular carcinoma suppresses tumor growth through inhibiting angiogenesis

Takashi Goto, Hiroki Ishikawa, Kojiro Matsumoto, Daisuke Nishimura, Mariko Kusaba, Naota Taura, Hidetaka Shibata, Hisamitsu Miyaaki, Tatsuki Ichikawa, Keisuke Hamasaki, Kazuhiko Nakao, Yohei Maeshima, Katsumi Eguchi
Pages: 33-40
Published online on: 01 July 2008

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Article

Inverse relationship between E-cadherin and p27Kip1 expression in renal cell carcinoma

Toshiro Migita, Yoshinao Oda, Katsuaki Masuda, Akira Hirata, Michihiko Kuwano, Seiji Naito, Masazumi Tsuneyoshi
Pages: 41-47
Published online on: 01 July 2008

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Article Open Access

Establishment of combined immuno-chemotherapy with systemically administered gemcitabine and intra-portal administration of interleukin-2 in murine models of liver metastases of pancreatic cancer

Yasuhiro Ito, Koichi Aiura, Masakazu Ueda, Masaki Kitajima, Yuko Kitagawa
Pages: 49-58
Published online on: 01 July 2008

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Article

Functional domains of CCN1 (Cyr61) regulate breast cancer progression

James O'Kelly, Alice Chung, Nathan Lemp, Katya Chumakova, Dong Yin, He-Jing Wang, Jonathan Said, Dorina Gui, Carl W. Miller, Beth Y. Karlan, H. Phillip Koeffler
Pages: 59-67
Published online on: 01 July 2008

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Article

Aberrant expression of cortactin and fascin are effective markers for pathogenesis, invasion, metastasis and prognosis of gastric carcinomas

Xiaohan Li, Huachuan Zheng, Takuo Hara, Hiroyuki Takahashi, Shinji Masuda, Zhigang Wang, Xianghong Yang, Yifu Guan, Yasuo Takano
Pages: 69-79
Published online on: 01 July 2008

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Article

ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells

Thanh-Hung Nguyen, Fatimah B. Mustafa, Shazib Pervaiz, Florence S.P. Ng, Lina H.K. Lim
Pages: 81-92
Published online on: 01 July 2008

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Article

Enhancement of T cell-mediated and humoral immunity of β-glucuronidase-based DNA vaccines against HPV16 E7 oncoprotein

Michal Smahel, Ingrid Poláková, Dana Pokorná, Viera Ludvíková, Martina Dusková, Josef Vlasák
Pages: 93-101
Published online on: 01 July 2008

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Article

Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel

Shougang Jiang, Yuangang Zu, Yuejie Fu, Yu Zhang, Thomas Efferth
Pages: 103-111
Published online on: 01 July 2008

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Article

Aberrant methylation of CXCL12 in non-small cell lung cancer is associated with an unfavorable prognosis Corrigendum in /ijo/47/2/791

Makoto Suzuki, Sherif Mohamed, Takahiro Nakajima, Rieko Kubo, Lei Tian, Taiki Fujiwara, Hidemi Suzuki, Kaoru Nagato, Masako Chiyo, Shinichiro Motohashi, Kazuhiro Yasufuku, Akira Iyoda, Shigetoshi Yoshida, Yasuo Sekine, Kiyoshi Shibuya, Kenzo Hiroshima, Yukio Nakatani, Ichiro Yoshino, Takehiko Fujisawa
Pages: 113-119
Published online on: 01 July 2008

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Combined therapy using suicide gef gene and paclitaxel enhances growth inhibition of multicellular tumour spheroids of A-549 human lung cancer cells

Jose Prados, Consolacion Melguizo, Ana Rama, Raul Ortiz, Houria Boulaiz, Fernando Rodriguez-Serrano, Octavio Caba, Jose Juan Rodriguez-Herva, Juan Luis Ramos, Antonia Aranega
Pages: 121-127
Published online on: 01 July 2008

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Article

Osteoprogenitor differentiation is not affected by immunomodulatory thalidomide analogs but is promoted by low bortezomib concentration, while both agents suppress osteoclast differentiation

Shoso Munemasa, Akira Sakai, Yoshiaki Kuroda, Yoshiko Okikawa, Yuta Katayama, Hideki Asaoku, Tadahiko Kubo, Shoji Shimose, Akiro Kimura
Pages: 129-136
Published online on: 01 July 2008

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Article

Differential expression of GHRH receptor and its splice variant 1 in human normal and malignant mucosa of the oesophagus and colon

Florian Hohla, Angelika Moder, Ursula Mayrhauser, Cornelia Hauser-Kronberger, Andrew V. Schally, Jozsef L. Varga, Marta Zarandi, Stefan Buchholz, Rudolf Huber, Elmar Aigner, Markus Ritter, Christian Datz
Pages: 137-143
Published online on: 01 July 2008

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Article

Poor outcome in adolescents with high-risk Hodgkin lymphoma

R. A. Herbertson, L. S. Evans, J. Hutchinson, J. Horsman, B. W. Hancock
Pages: 145-151
Published online on: 01 July 2008

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Article

MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells

Takeshi Kawano, Rehan Ahmad, Hiroko Nogi, Naoki Agata, Kenneth Anderson, Donald Kufe
Pages: 153-159
Published online on: 01 July 2008

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Article

Targeted inhibition of Sp1-mediated transcription for antiangiogenic therapy of metastatic human gastric cancer in orthotopic nude mouse models

Liwei Wang, Xiaohong Guan, Jun Zhang, Zhiliang Jia, Daoyan Wei, Qiang Li, James Yao, Keping Xie
Pages: 161-167
Published online on: 01 July 2008

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Article

CD31 density is a novel risk factor for patients with B-cell chronic lymphocytic leukaemia

Tryfonia Mainou-Fowler, Alistair Porteous, Annette Nicolle, Stephen John Proctor, John James Anderson, Geoffrey Summerfield
Pages: 169-174
Published online on: 01 July 2008

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Article

siRNA targeting the IRF2 transcription factor inhibits leukaemic cell growth

Ailyn Choo, Patricia Palladinetti, Tiffany Holmes, Shreerupa Basu, Sylvie Shen, Richard B. Lock, Tracey A. O'Brien, Geoff Symonds, Alla Dolnikov
Pages: 175-183
Published online on: 01 July 2008

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Article

Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism

Teresa Gómez del Pulgar, Fátima Valdés-Mora, Eva Bandrés, Rosa Pérez-Palacios, Carolina Espina, Paloma Cejas, Miguel Angel García-Cabezas, Manuel Nistal, Enrique Casado, Manuel González-Barón, Jesús García-Foncillas, Juan Carlos Lacal
Pages: 185-193
Published online on: 01 July 2008

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Article

Protein levels and gene expressions of the epidermal growth factor receptors, HER1, HER2, HER3 and HER4 in benign and malignant ovarian tumors

Karina Dahl Steffensen, Marianne Waldstrøm, Rikke Fredslund Andersen, Dorte Aalund Olsen, Ulla Jeppesen, Hans Jørgen Knudsen, Ivan Brandslund, Anders Jakobsen
Pages: 195-204
Published online on: 01 July 2008

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Article

Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine

Yong Hwan Han, Sung Zoo Kim, Suhn Hee Kim, Woo Hyun Park
Pages: 205-213
Published online on: 01 July 2008

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Article

Tumor growth inhibition by synthetic and expressed siRNA targeting focal adhesion kinase

Kae Tsutsumi, Tatsuhiko Kasaoka, Hyi-Man Park, Hiroko Nishiyama, Motowo Nakajima, Toshiyuki Honda
Pages: 215-224
Published online on: 01 July 2008

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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