Journal Articles
Review
STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (Review)
Xiaochun Wang, Philip J. Crowe, David Goldstein, Jia-Lin Yang
Pages: 1181-1191 Published online on: 24 July 2012
Article
Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer
Katsuyuki Iida, Rong Zheng, Ruoqian Shen, David M. Nanus
Pages: 1192-1198 Published online on: 08 August 2012
Article
Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer
Ka Wing Cheng, George Mattheolabakis, Chi C. Wong, Nengtai Ouyang, Liqun Huang, Panayiotis P. Constantinides, Basil Rigas
Pages: 1199-1203 Published online on: 27 July 2012
Article
Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab
Peter Grell, Pavel Fabian, Marta Khoylou, Lenka Radova, Ondrej Slaby, Roman Hrstka, Rostislav Vyzula, Marian Hajduch, Marek Svoboda
Pages: 1204-1212 Published online on: 27 July 2012
Article
First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI)
K. Eichler, S. Zangos, M. G. Mack, R. Hammerstingl, T. Gruber-Rouh, C. Gallus, T. J. Vogl
Pages: 1213-1220 Published online on: 25 July 2012
Article
Alterations of MEN1 and E-cadherin/β-catenin complex in sporadic pulmonary carcinoids
Serena Veschi, Rossano Lattanzio, Gitana Maria Aceto, Maria Cristina Curia, Salvatore Magnasco, Domenico Angelucci, Alessandro Cama, Mauro Piantelli, Pasquale Battista
Pages: 1221-1228 Published online on: 20 July 2012
Article
Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma
Claire Taylor, Rachel A. Craven, Patricia Harnden, Peter J. Selby, Rosamonde E. Banks
Pages: 1229-1240 Published online on: 20 July 2012
Article
A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire
Nadia Saucedo-Zeni, Steffi Mewes, Robert Niestroj, Lukasz Gasiorowski, David Murawa, Piotr Nowaczyk, Tatiana Tomasi, Ekkehard Weber, Grzegorz Dworacki, Nils G. Morgenthaler, Heike Jansen, Corinna Propping, Karolina Sterzynska, Wojciech Dyszkiewicz, Maciej Zabel, Marion Kiechle, Ute Reuning, Manfred Schmitt, Klaus Lücke
Pages: 1241-1250 Published online on: 16 July 2012
Article
Radiofrequency currents exert cytotoxic effects in NB69 human neuroblastoma cells but not in peripheral blood mononuclear cells
María Luisa Hernández-Bule, Ernesto Roldán, Joaquín Matilla, María Ángeles Trillo, Alejandro Úbeda
Pages: 1251-1259 Published online on: 24 July 2012
Article
Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma
Arnulf Mayer, Fabienne Schneider, Peter Vaupel, Clemens Sommer, Heinz Schmidberger
Pages: 1260-1270 Published online on: 16 July 2012
Article
Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells
Doreen Kunze, Kai Kraemer, Kati Erdmann, Michael Froehner, Manfred P. Wirth, Susanne Fuessel
Pages: 1271-1277 Published online on: 06 July 2012
Article
Inhibitory effect of PPARγ on NR0B1 in tumorigenesis of lung adenocarcinoma
Yoshiyuki Susaki, Masayoshi Inoue, Masato Minami, Noriyoshi Sawabata, Yasushi Shintani, Tomoyuki Nakagiri, Soichiro Funaki, Katsuyuki Aozasa, Meinoshin Okumura, Eiichi Morii
Pages: 1278-1284 Published online on: 25 July 2012
Article
Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis
Minh‑Hue Nguyen, Koji Ueda, Yusuke Nakamura, Yataro Daigo
Pages: 1285-1296 Published online on: 10 August 2012
Article
Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer
Toru Masuzawa, Yoshiyuki Fujiwara, Kaoru Okada, Ayumu Nakamura, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Makoto Yamasaki, Yukinori Kurokawa, Ryuji Osawa, Kazuyoshi Takeda, Koji Yoshida, Takuya Tsunoda, Yusuke Nakamura, Masaki Mori, Yuichiro Doki
Pages: 1297-1304 Published online on: 25 July 2012
Article
Role of metallothionein 1E in the migration and invasion of human glioma cell lines
Hyang-Hwa Ryu, Shin Jung, Tae-Young Jung, Kyung-Sub Moon, In-Young Kim, Young-Il Jeong, Shu-Guang Jin, Jian Pei, Min Wen, Woo-Yeol Jang
Pages: 1305-1313 Published online on: 24 July 2012
Article
Expression of cancer stem cell markers in pancreatic intraepithelial neoplasias and pancreatic ductal adenocarcinomas
Shoko Kure, Yoko Matsuda, Masahito Hagio, Junji Ueda, Zenya Naito, Toshiyuki Ishiwata
Pages: 1314-1324 Published online on: 23 July 2012
Article
IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy
Yoshiko Okita, Yoshitaka Narita, Yasuji Miyakita, Makoto Ohno, Yuko Matsushita, Shintaro Fukushima, Minako Sumi, Koichi Ichimura, Takamasa Kayama, Soichiro Shibui
Pages: 1325-1336 Published online on: 20 July 2012
Article
The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer
Yunyan Wu, Fuyuki Sato, Toshiyuki Yamada, Ujjal Kumar Bhawal, Takeshi Kawamoto, Katsumi Fujimoto, Mitsuhide Noshiro, Hiroko Seino, Satoko Morohashi, Kenichi Hakamada, Yoshimitsu Abiko, Yukio Kato, Hiroshi Kijima
Pages: 1337-1346 Published online on: 18 July 2012
Article
Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis
Hideo Nakajima, Keita Koizumi, Takuji Tanaka, Yasuhito Ishigaki, Yoshino Yoshitake, Hideto Yonekura, Tsutomu Sakuma, Toshihiro Fukushima, Hisanori Umehara, Soichiro Ueno, Toshinari Minamoto, Yoshiharu Motoo
Pages: 1347-1357 Published online on: 10 July 2012
Article
Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules
Jae Ju Jeong, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim
Pages: 1358-1364 Published online on: 07 August 2012
Article
Novel monoclonal antibodies specific for CTLD-SSC and sialomucin domains of endosialin, a mural cell marker of tumor vasculature
Soňa Kontseková, Anna Ohradanova Repic, Katarína Polčicová, Pauliina Tuomaala, Jaromír Pastorek, Silvia Pastoreková, Seppo Parkkila, Monika Baráthová
Pages: 1365-1372 Published online on: 23 July 2012
Article
Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation
Saly Hafiz, John C. Dennis, Dean Schwartz, Robert Judd, Ya‑Xiong Tao, Kamel Khazal, Benson Akingbemi, Xiu-Lei Mo, Asim B. Abdel‑Mageed, Edward Morrison, Mahmoud Mansour
Pages: 1373-1380 Published online on: 25 July 2012
Article
The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy
Anaïs Altmeyer, Elodie Josset, Jean-Marc Denis, John Gueulette, Jakobus Slabbert, Didier Mutter, Georges Noël, Pierre Bischoff
Pages: 1381-1386 Published online on: 07 August 2012
Article
A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis
Ying-Wooi Wan, Rebecca A. Raese, James E. Fortney, Changchang Xiao, Dajie Luo, John Cavendish, Laura F. Gibson, Vincent Castranova, Yong Qian, Nancy Lan Guo
Pages: 1387-1396 Published online on: 16 July 2012
Article
Genomic CGH-assessed structural DNA alterations in rectal carcinoma as related to local recurrence following primary operation for cure
K. Kodeda, A. Gustafsson Asting, C. Lönnroth, K. Derwinger, Y. Wettergren, S. Nordgren, B. Gustavsson, K. Lundholm
Pages: 1397-1404 Published online on: 20 July 2012
Article
A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients
Santanu Dasgupta, Prodipto Pal, Nitai D. Mukhopadhyay, Yumei Fu, Edward A. Ratovitski, Chul-So Moon, Mohammad Obaidul Hoque, Paul B. Fisher, Barry Trink
Pages: 1405-1410 Published online on: 23 July 2012
Article
The Hedgehog signaling pathway in ovarian teratoma is stimulated by Sonic Hedgehog which induces internalization of Patched
Maja Sabol, Diana Car, Vesna Musani, Petar Ozretic, Slavko Oreskovic, Igor Weber, Sonja Levanat
Pages: 1411-1418 Published online on: 13 July 2012
Article
Cytokine-like 1 is involved in the growth and metastasis of neuroblastoma cells
Mingjie Wen, Huanmin Wang, Xulong Zhang, Jun Long, Zhe Lv, Qingli Kong, Yunqing An
Pages: 1419-1424 Published online on: 13 July 2012
Article
Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2
Sung-Jun Lee, Eun-Ae Kim, Kyoung Seob Song, Min-Jae Kim, Dae Hyung Lee, Taeg Kyu Kwon, Tae-Jin Lee
Pages: 1425-1430 Published online on: 27 July 2012
Article
Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells
Shih-Chang Tsai, Jai-Sing Yang, Shu-Fen Peng, Chi-Cheng Lu, Jo-Hua Chiang, Jing-Gung Chung, Meng-Wei Lin, Jen-Kun Lin, Sakae Amagaya, Cinderella Wai-Shan Chung, Theng-Thang Tung, Wen-Wen Huang, Michael T. Tseng
Pages: 1431-1442 Published online on: 31 July 2012
Article
Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells
Seung Hee Yoo, Young Geol Yoon, Jee Suk Lee, Yeon Suk Song, Joon Seok Oh, Bong Soo Park, Taeg Kyu Kwon, Cheol Park, Yung Hyun Choi, Young Hyun Yoo
Pages: 1443-1454 Published online on: 07 August 2012
Article
Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor
Ruediger Liersch, Jay W. Shin, Michael Bayer, Christian Schwöppe, Christoph Schliemann, Wolfgang E. Berdel, Rolf Mesters, Michael Detmar
Pages: 1455-1463 Published online on: 06 July 2012
Article
Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells
Haley L. Peters, Amit Tuli, Xiaojian Wang, Cuiling Liu, Zenggang Pan, Michel M. Ouellette, Michael A. Hollingsworth, Richard G. MacDonald, Joyce C. Solheim
Pages: 1464-1474 Published online on: 13 July 2012
Article
Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia
Denis G. Alferez, Robert A. Goodlad, Rajesh Odedra, Patrizia Sini, Claire Crafter, Anderson J. Ryan, Stephen R. Wedge, Nicholas A. Wright, Elizabeth Anderson, Robert W. Wilkinson
Pages: 1475-1485 Published online on: 31 July 2012
Article
SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line
Daniela Bellarosa, Alessandro Bressan, Mario Bigioni, Massimo Parlani, Carlo Alberto Maggi, Monica Binaschi
Pages: 1486-1494 Published online on: 13 July 2012
Article
Arachidonic acid metabolism in human prostate cancer
Peiying Yang, Carrie A. Cartwright, Jin Li, Sijin Wen, Ina N. Prokhorova, Imad Shureiqi, Patricia Troncoso, Nora M. Navone, Robert A. Newman, Jeri Kim
Pages: 1495-1503 Published online on: 10 August 2012
Article
The enhanced antitumor effects of biodegradable cationic heparin-polyethyleneimine nanogels delivering HSulf-1 gene combined with cisplatin on ovarian cancer
Ping Liu, Maling Gou, Tao Yi, Xiaorong Qi, Chuan Xie, Shengtao Zhou, Hongxin Deng, Yuquan Wei, Xia Zhao
Pages: 1504-1512 Published online on: 18 July 2012
Article
Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells
Mann-Jen Hour, Shih-Chang Tsai, Hsi-Chin Wu, Meng-Wei Lin, Jing‑Gung Chung, Jin-Bin Wu, Jo-Hua Chiang, Minoru Tsuzuki, Jai-Sing Yang
Pages: 1513-1519 Published online on: 18 July 2012
Article
Silencing of SNX1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines
Yukio Nishimura, Soichi Takiguchi, Kiyoko Yoshioka, Yusaku Nakabeppu, Kazuyuki Itoh
Pages: 1520-1530 Published online on: 31 July 2012
Article
The NEDD8 conjugation pathway regulates p53 transcriptional activity and head and neck cancer cell sensitivity to ionizing radiation
Sébastien Guihard, Ludivine Ramolu, Christine Macabre, Bohdan Wasylyk, Georges Noël, Joseph Abecassis, Alain C. Jung
Pages: 1531-1540 Published online on: 07 August 2012
Article
Biological influence of brain-derived neurotrophic factor on breast cancer cells
Xiaomei Yang, Tracey A. Martin, Wen G. Jiang
Pages: 1541-1546 Published online on: 06 August 2012
Article
