Journal Articles
Review
Therapeutic potential of targeting mTOR in T-cell acute lymphoblastic leukemia (Review)
Camilla Evangelisti, Cecilia Evangelisti, Francesca Chiarini, Annalisa Lonetti, Francesca Buontempo, Daniela Bressanin, Alessandra Cappellini, Ester Orsini, James A. McCubrey, Alberto M. Martelli
Pages: 909-918 Published online on: 26 June 2014
Review
Emerging targets to monitor and overcome docetaxel resistance in castration resistant prostate cancer (Review)
L. Magadoux, N. Isambert, S. Plenchette, J. F. Jeannin, V. Laurens
Pages: 919-928 Published online on: 24 June 2014
Review
Towards combinatorial targeted therapy in melanoma: From pre-clinical evidence to clinical application (Review)
Giulia Grazia, Ilaria Penna, Valentina Perotti, Andrea Anichini, Elena Tassi
Pages: 929-949 Published online on: 10 June 2014
Review
MicroRNAs in the diagnosis and prognosis of breast cancer and their therapeutic potential (Review)
Kaiyuan Zhang, Yanlei Zhang, Chang Liu, Ying Xiong, Jiqiang Zhang
Pages: 950-958 Published online on: 10 June 2014
Review
Inflammatory cues acting on the adult intestinal stem cells and the early onset of cancer (Review)
A. De Lerma Barbaro, G. Perletti, I. M. Bonapace, E. Monti
Pages: 959-968 Published online on: 10 June 2014
Review
TRAP1 revisited: Novel localizations and functions of a ‘next-generation’ biomarker (Review)
Maria Rosaria Amoroso, Danilo Swann Matassa, Lorenza Sisinni, Giacomo Lettini, Matteo Landriscina, Franca Esposito
Pages: 969-977 Published online on: 27 June 2014
Article
Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells
Zhongyun Dong, Jaroslaw Meller, Paul Succop, Jiang Wang, Kathryn Wikenheiser-Brokamp, Sandra Starnes, Shan Lu
Pages: 978-984 Published online on: 10 June 2014
Article
Functional characteristics of cancer stem cells and their role in drug resistance of prostate cancer
Viviana Castillo, Rodrigo Valenzuela, Christian Huidobro, Hector R. Contreras, Enrique A. Castellon
Pages: 985-994 Published online on: 27 June 2014
Article
Enhanced anti-colorectal cancer effects of carfilzomib combined with CPT-11 via downregulation of nuclear factor-κB in vitro and in vivo
Weiwei Tang, Guangjian Su, Jieyu Li, Jinrong Liao, Shuping Chen, Chuanzhong Huang, Fang Liu, Qiang Chen, Yunbin Ye
Pages: 995-1010 Published online on: 23 June 2014
Article
Induction of apoptosis by a peptide from Porphyra yezoensis: Regulation of the insulin-like growth factor I receptor signaling pathway in MCF-7 cells
Su-Jin Park, Jina Ryu, In-Hye Kim, Youn-Hee Choi, Taek-Jeong Nam
Pages: 1011-1016 Published online on: 20 June 2014
Article
Prediction of concurrent chemoradiotherapy outcome in advanced oropharyngeal cancer
Masahiro Hasegawa, Hiroyuki Maeda, Zeyi Deng, Asanori Kiyuna, Akira Ganaha, Yukashi Yamashita, Sen Matayoshi, Shinya Agena, Takafumi Toita, Takayuki Uehara, Mikio Suzuki
Pages: 1017-1026 Published online on: 18 June 2014
Article
NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells
Du G. Moon, Sang E. Lee, Mi M. Oh, Sang C. Lee, Seong J. Jeong, Sung K. Hong, Cheol Y. Yoon, Seok S. Byun, Hong S. Park, Jun Cheon
Pages: 1027-1035 Published online on: 19 June 2014
Article
Phloroglucinol induces apoptosis through the regulation of insulin-like growth factor 1 receptor signaling pathways in human colon cancer HT-29 cells
Mi-Hye Kang, In-Hye Kim, Taek-Jeong Nam
Pages: 1036-1042 Published online on: 24 June 2014
Article
Protein kinase C ζ regulates survivin expression and inhibits apoptosis in colon cancer
Yoshifumi Umemori, Kageaki Kuribayashi, Shinya Nirasawa, Takashi Kondoh, Maki Tanaka, Daisuke Kobayashi, Naoki Watanabe
Pages: 1043-1050 Published online on: 10 June 2014
Article
Association between ephrin-A1 mRNA expression and poor prognosis after hepatectomy to treat hepatocellular carcinoma
Hiroshi Wada, Hirofumi Yamamoto, Chiwan Kim, Mamoru Uemura, Hirofumi Akita, Yoshito Tomimaru, Naoki Hama, Koichi Kawamoto, Shogo Kobayashi, Hidetoshi Eguchi, Koji Umeshita, Yuichiro Doki, Masaki Mori, Hiroaki Nagano
Pages: 1051-1058 Published online on: 24 June 2014
Article
Human β-defensin-3 inhibits migration of colon cancer cells via downregulation of metastasis-associated 1 family, member 2 expression Corrigendum in /ijo/46/4/1858
Satoko Uraki, Kazushi Sugimoto, Katsuya Shiraki, Masahiko Tameda, Yuji Inagaki, Suguru Ogura, Chika Kasai, Keiichiro Nojiri, Misao Yoneda, Norihiko Yamamoto, Yoshiyuki Takei, Tsutomu Nobori, Masaaki Ito
Pages: 1059-1064 Published online on: 20 June 2014
Article
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE‑cadherin/EphA2/MMP9/MMP2 expression
Jing-Qiang Guo, Qing-Hui Zheng, Hui Chen, Liang Chen, Jin-Bo Xu, Min-Yuan Chen, Dian Lu, Zhao-Hong Wang, Hong-Fei Tong, Shengzhang Lin
Pages: 1065-1072 Published online on: 16 June 2014
Article
CD7 promotes extramedullary involvement of the B-cell acute lymphoblastic leukemia line Tanoue by enhancing integrin β2-dependent cell adhesiveness
Takashi Kondoh, Kageaki Kuribayashi, Maki Tanaka, Daisuke Kobayashi, Nozomi Yanagihara, Naoki Watanabe
Pages: 1073-1081 Published online on: 11 June 2014
Article
Clinical significance of early interventional therapy of branched-chain amino acid granules in patients with hepatocellular carcinoma: Propensity score matching analysis
Hiroki Nishikawa, Ryuichi Kita, Toru Kimura, Yoshiaki Ohara, Haruhiko Takeda, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Yukio Osaki
Pages: 1082-1090 Published online on: 24 June 2014
Article
Association of EMP1 with gastric carcinoma invasion, survival and prognosis
Guogui Sun, Gang Zhao, Yifang Lu, Yadi Wang, Congrong Yang
Pages: 1091-1098 Published online on: 10 June 2014
Article
Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagy
Jin-Hua He, Xiao-Li Liao, Wei Wang, Dan-Dan Li, Wen-Dan Chen, Rong Deng, Dajun Yang, Ze-Ping Han, Jian-Wei Jiang, Xiao-Feng Zhu
Pages: 1099-1108 Published online on: 11 June 2014
Article
The combined treatment with chloroquine and the enzymatic oxidation products of spermine overcomes multidrug resistance of melanoma M14 ADR2 cells: A new therapeutic approach
Enzo Agostinelli, Maria Condello, Giampiero Tempera, Alberto Macone, Giuseppina Bozzuto, Shinji Ohkubo, Annarica Calcabrini, Giuseppe Arancia, Agnese Molinari
Pages: 1109-1122 Published online on: 18 June 2014
Article
Intestinal trefoil factor activates the PI3K/Akt signaling pathway to protect gastric mucosal epithelium from damage
Zhaorui Sun, Hongmei Liu, Zhizhou Yang, Danbing Shao, Wei Zhang, Yi Ren, Baodi Sun, Jinfeng Lin, Min Xu, Shinan Nie
Pages: 1123-1132 Published online on: 27 June 2014
Article
Identification of differentially expressed genes and their subpathways in recurrent versus primary bone giant cell tumors
Shuxin Chen, Chunquan Li, Bingli Wu, Chunlong Zhang, Cheng Liu, Xiaoxu Lin, Xiangqiao Wu, Lingling Sun, Chunpeng Liu, Bo Chen, Zhigang Zhong, Liyan Xu, Enmin Li
Pages: 1133-1142 Published online on: 18 June 2014
Article
The co-localization of HBx and COXIII upregulates COX-2 promoting HepG2 cell growth
Bi-Yun Zheng, Xue-Fen Fang, Lai-Yu Zou, Yue-Hong Huang, Zhi-Xin Chen, Dan Li, Lin-Ying Zhou, Hao Chen, Xiao-Zhong Wang
Pages: 1143-1150 Published online on: 16 June 2014
Article
Interference of Ca2+ with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells
Anna Otte, Finn Rauprich, Juliane von der Ohe, Peter Hillemanns, Ralf Hass
Pages: 1151-1158 Published online on: 24 June 2014
Article
Association between cellular radiosensitivity and G1/G2 checkpoint proficiencies in human cholangiocarcinoma cell lines
Arunee Hematulin, Daniel Sagan, Kanlayanee Sawanyawisuth, Wunchana Seubwai, Sopit Wongkham
Pages: 1159-1166 Published online on: 24 June 2014
Article
Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations
Sandy Chevrier, Laurent Arnould, François Ghiringhelli, Bruno Coudert, Pierre Fumoleau, Romain Boidot
Pages: 1167-1174 Published online on: 27 June 2014
Article
Characterization of side population cells isolated from the colon cancer cell line SW480
Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Pages: 1175-1183 Published online on: 13 June 2014
Article
Overexpression of Yin Yang 1 in bone marrow-derived human multiple myeloma and its clinical significance
Sara Huerta-Yepez, Hong Liu, Stavroula Baritaki, Maria Del Lourdes Cebrera‑Muñoz, Clara Rivera-Pazos, Altagracia Maldonado-Valenzuela, Alberto Valencia-Hipolito, Mario I. Vega, Haiming Chen, James R. Berenson, Benjamin Bonavida
Pages: 1184-1192 Published online on: 20 June 2014
Article
Inhibition of Cdk2 kinase activity selectively targets the CD44+/CD24-/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells
Mateusz Opyrchal, Jeffrey L. Salisbury, Ianko Iankov, Mathew P. Goetz, James McCubrey, Mario W. Gambino, Lorenzo Malatino, Giuseppe Puccia, James N. Ingle, Evanthia Galanis, Antonino B. D'Assoro
Pages: 1193-1199 Published online on: 25 June 2014
Article
Microarray analysis of gene expression by microdissected epidermis and dermis in mycosis fungoides and adult T-cell leukemia/lymphoma
Keiko Hashikawa, Shinichiro Yasumoto, Kazutaka Nakashima, Fumiko Arakawa, Junichi Kiyasu, Yoshizo Kimura, Hiroshi Saruta, Takekuni Nakama, Kaori Yasuda, Kosuke Tashiro, Satoru Kuhara, Takashi Hashimoto, Koichi Ohshima
Pages: 1200-1208 Published online on: 26 June 2014
Article
Buccal microRNA dysregulation in lung field carcinogenesis: Gender-specific implications
Ramesh K. Wali, Thomas A. Hensing, Daniel W. Ray, Mart Dela Cruz, Ashish K. Tiwari, Andrew Radosevich, Lisa Jepeal, Hiran C. Fernando, Virginia R. Litle, Marjory Charlot, Navneet Momi, Vadim Backman, Hemant K. Roy
Pages: 1209-1215 Published online on: 11 June 2014
Article
Knockdown of hTERT by siRNA inhibits cervical cancer cell growth in vitro and in vivo
Ying-Ai Shi, Qiang Zhao, Li-Hong Zhang, Wei Du, Xue-Yao Wang, Xu He, Shan Wu, Yu-Lin Li
Pages: 1216-1224 Published online on: 11 June 2014
Article
MicroRNA-124 regulates TGF-α-induced epithelial-mesenchymal transition in human prostate cancer cells
Wei Qin, Yujia Pan, Xiulan Zheng, Dong Li, Jingyi Bu, Chunyan Xu, Jiebing Tang, Rongjun Cui, Ping Lin, Xiaoguang Yu
Pages: 1225-1231 Published online on: 19 June 2014
Article
Sine oculis homeobox homolog 1 promotes DNA replication and cell proliferation in cervical cancer
Dan Liu, Xiao-Xue Zhang, Bi-Xin Xi, Dong-Yi Wan, Li Li, Jin Zhou, Wei Wang, Ding Ma, Hui Wang, Qing-Lei Gao
Pages: 1232-1240 Published online on: 20 June 2014
Article
Knockdown of IGF2R suppresses proliferation and induces apoptosis in hemangioma cells in vitro and in vivo
J.-M. Ou, W.-S. Lian, M.-K. Qiu, Y.-X. Dai, Q. Dong, J. Shen, P. Dong, X.-F. Wang, Y.-B. Liu, Z.-W. Quan, Z.-W. Fei
Pages: 1241-1249 Published online on: 23 June 2014
Article
Anti-inflammatory effects of betaine on AOM/DSS‑induced colon tumorigenesis in ICR male mice
Dong Hwan Kim, Bokyung Sung, Yong Jung Kang, Jung Yoon Jang, Seong Yeon Hwang, Yujin Lee, Minjung Kim, Eunok Im, Jeong-Hyun Yoon, Cheol Min Kim, Hae Young Chung, Nam Deuk Kim
Pages: 1250-1256 Published online on: 24 June 2014
Article
miR-126 inhibits growth of SGC-7901 cells by synergistically targeting the oncogenes PI3KR2 and Crk, and the tumor suppressor PLK2
Li Ying Liu, Wei Wang, Lin Yu Zhao, Bo Guo, Juan Yang, Xiao Ge Zhao, Ni Hou, Lei Ni, Ai Ying Wang, Tu Sheng Song, Chen Huang, Ji Ru Xu
Pages: 1257-1265 Published online on: 24 June 2014
Article
Downregulation of NEK11 is associated with drug resistance in ovarian cancer
Xia Liu, Yutao Gao, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin
Pages: 1266-1274 Published online on: 18 June 2014
Article
Epigenetic alterations are involved in the overexpression of glutathione S-transferase π-1 in human colorectal cancers
Rui Zhang, Kyoung Ah Kang, Mei Jing Piao, Ki Cheon Kim, Jian Zheng, Cheng Wen Yao, Ji Won Cha, Young Hee Maeng, Weon Young Chang, Pyong-Gon Moon, Moon-Chang Baek, Jin Won Hyun
Pages: 1275-1283 Published online on: 25 June 2014
Article
The hexane fraction of Naematoloma sublateritium extract suppresses the TNF-α-induced metastatic potential of MDA-MB-231 breast cancer cells through modulation of the JNK and p38 pathways
Yu Ran Lee, Ki Mo Kim, Byeong Hwa Jeon, Sunga Choi
Pages: 1284-1292 Published online on: 27 June 2014
Article
Telomerase (GV1001) vaccination together with gemcitabine in advanced pancreatic cancer patients
Caroline Staff, Fariba Mozaffari, Jan-Erik Frödin, Håkan Mellstedt, Maria Liljefors
Pages: 1293-1303 Published online on: 11 June 2014
Article
Tumour angiogenesis and repulsive guidance molecule b: A role in HGF- and BMP-7-mediated angiogenesis
Andrew J. Sanders, Lin Ye, Jin Li, Malcolm D. Mason, Wen G. Jiang
Pages: 1304-1312 Published online on: 20 June 2014
Article