Journal Articles
Review
Long non‑coding RNAs drive metastatic progression in melanoma (Review)
Pouria Akhbari, Adrian Whitehouse, James R. Boyne
Pages: 2181-2186 Published online on: 01 October 2014
Review
Significance of AKT in gastric cancer (Review)
Takamitsu Sasaki, Hiroki Kuniyasu
Pages: 2187-2192 Published online on: 26 September 2014
Review
Cytoreductive prostatectomy: Evidence in support of a new surgical paradigm (Review)
Izak Faiena, Eric A. Singer, Chris Pumill, Isaac Y. Kim
Pages: 2193-2198 Published online on: 17 September 2014
Review
Roles of F‑box proteins in human digestive system tumors (Review)
Jian Gong, Liang Lv, Jirong Huo
Pages: 2199-2207 Published online on: 29 September 2014
Article
Preoperative low dose NSAID treatment influences the genes for stemness, growth, invasion and metastasis in colorectal cancer
Christina Lönnroth, Marianne Andersson, Annika G. Asting, Svante Nordgren, Kent Lundholm
Pages: 2208-2220 Published online on: 30 September 2014
Article
A phase I dose-escalation study to a predefined dose of a transforming growth factor-β1 monoclonal antibody (TβM1) in patients with metastatic cancer
Allen Cohn, Michael M. Lahn, Kristen E. Williams, Ann L. Cleverly, Celine Pitou, Sunil K. Kadam, Mark W. Farmen, Durisala Desaiah, Robert Raju, Paul Conkling, Donald Richards
Pages: 2221-2231 Published online on: 26 September 2014
Article
Expression and clinical significance of CXCR5/CXCL13 in human non‑small cell lung carcinoma
Rajesh Singh, Pranav Gupta, Goetz H. Kloecker, Shailesh Singh, James W. Lillard Jr
Pages: 2232-2240 Published online on: 30 September 2014
Article
A model of spontaneous mouse mammary tumor for human estrogen receptor- and progesterone receptor-negative breast cancer
Lixiang Zheng, Bugao Zhou, Xianming Meng, Weifeng Zhu, Airen Zuo, Xiaomin Wang, Runde Jiang, Shiping Yu
Pages: 2241-2249 Published online on: 17 September 2014
Article
Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers
Ramon G. Manzano, Elena M. Martinez-Navarro, Jeronimo Forteza, Antonio Brugarolas
Pages: 2250-2266 Published online on: 09 September 2014
Article
The inhibition of tyrosine kinase receptor signalling in leiomyosarcoma cells using the small molecule kinase inhibitor PTK787/ZK222584 (Vatalanib®)
Andreas K.A. Gaumann, Hannes C.A. Drexler, Sven A. Lang, Oliver Stoeltzing, Simone Diermeier‑Daucher, Elisabeth Buchdunger, Jeanette Wood, Guido Bold, Georg Breier
Pages: 2267-2277 Published online on: 29 September 2014
Article
Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway
Ken Sadahira, Morihiko Sagawa, Tomonori Nakazato, Hideo Uchida, Yasuo Ikeda, Shinichiro Okamoto, Hideaki Nakajima, Masahiro Kizaki
Pages: 2278-2286 Published online on: 15 September 2014
Article
Thrombin conducts epithelial‑mesenchymal transition via protease‑activated receptor‑1 in human gastric cancer
Tadayoshi Otsuki, Daisuke Fujimoto, Yasuo Hirono, Takanori Goi, Akio Yamaguchi
Pages: 2287-2294 Published online on: 15 September 2014
Article
Comparison of standard-dose and half‑dose sorafenib therapy on clinical outcome in patients with unresectable hepatocellular carcinoma in field practice: A propensity score matching analysis
Hiroki Nishikawa, Yukio Osaki, Masatsugu Endo, Haruhiko Takeda, Kaoru Tsuchiya, Kouji Joko, Chikara Ogawa, Hiroyoshi Taniguchi, Etsuro Orito, Yasushi Uchida, Namiki Izumi
Pages: 2295-2302 Published online on: 16 September 2014
Article
Kupffer cells decrease metastasis of colon cancer cells to the liver in the early stage
Hideki Matsumura, Tadashi Kondo, Koichi Ogawa, Takafumi Tamura, Kiyoshi Fukunaga, Soichiro Murata, Nobuhiro Ohkohchi
Pages: 2303-2310 Published online on: 18 September 2014
Article
Effects of metformin on retinoblastoma growth in vitro and in vivo
Katarzyna Brodowska, Sofia Theodoropoulou, Melissa Meyer Zu Hörste, Eleftherios I. Paschalis, Kimio Takeuchi, Gordon Scott, David J. Ramsey, Elizabeth Kiernan, Mien Hoang, Joanna Cichy, Joan W. Miller, Evangelos S. Gragoudas, Demetrios G. Vavvas
Pages: 2311-2324 Published online on: 11 September 2014
Article
Biphasic ER-α36-mediated estrogen signaling regulates growth of gastric cancer cells
Xuming Wang, Xuan Huang, Zhengqi Fu, Feng Zou, Yan Li, Zhaoyi Wang, Lijiang Liu
Pages: 2325-2330 Published online on: 17 September 2014
Article
Viriditoxin regulates apoptosis and autophagy via mitotic catastrophe and microtubule formation in human prostate cancer cells
Soma Kundu, Tae Hyung Kim, Jung Hyun Yoon, Han-Seung Shin, Jaewon Lee, Jee H. Jung, Hyung Sik Kim
Pages: 2331-2340 Published online on: 17 September 2014
Article
p62/SQSTM1 is involved in cisplatin resistance in human ovarian cancer cells via the Keap1-Nrf2-ARE system
Meihui Xia, Huimei Yu, Shuang Gu, Ye Xu, Jing Su, Hongyan Li, Jinsong Kang, Manhua Cui
Pages: 2341-2348 Published online on: 24 September 2014
Article
Identification of chemoradiation-resistant osteosarcoma stem cells using an imaging system for proteasome activity
Keisuke Tamari, Kazuhiko Hayashi, Hideshi Ishii, Yoshihiro Kano, Masamitsu Konno, Koichi Kawamoto, Naohiro Nishida, Jun Koseki, Takahito Fukusumi, Shinichiro Hasegawa, Hisataka Ogawa, Atsushi Hamabe, Masaaki Miyo, Kozo Noguchi, Yuji Seo, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa
Pages: 2349-2354 Published online on: 24 September 2014
Article
Downregulation of FoxM1 inhibits proliferation, invasion and angiogenesis of HeLa cells in vitro and in vivo
Hong Chen, Yang Zou, Hong Yang, Jingjing Wang, Hong Pan
Pages: 2355-2364 Published online on: 09 September 2014
Article
Cancer stem cells are enriched in Fanconi anemia head and neck squamous cell carcinomas
Jean Wu, Qingshan Mu, Varatharasa Thiviyanathan, Ananth Annapragada, Nadarajah Vigneswaran
Pages: 2365-2372 Published online on: 26 September 2014
Article
Potential crosstalk of Ca2+-ROS-dependent mechanism involved in apoptosis of Kasumi-1 cells mediated by heme oxygenase-1 small interfering RNA
Sixi Wei, Yating Wang, Qixiang Chai, Qin Fang, Yaming Zhang, Jishi Wang
Pages: 2373-2384 Published online on: 17 September 2014
Article
Silencing HIWI suppresses the growth, invasion and migration of glioma cells
Xiuyu Wang, Xiaoguang Tong, Hongmei Gao, Xiaoling Yan, Xinnv Xu, Shupeng Sun, Qiong Wang, Jinhuan Wang
Pages: 2385-2392 Published online on: 25 September 2014
Article
Cantharidin induces G2/M phase arrest by inhibition of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria‑dependent pathways of A375.S2 human melanoma cells
Yu‑Ping Hsiao, Chung-Hung Tsai, Ping‑Ping Wu, Shu‑Chun Hsu, Hsin‑Chung Liu, Yi‑Ping Huang, Jen‑Hung Yang, Jing‑Gung Chung
Pages: 2393-2402 Published online on: 30 September 2014
Article
MicroRNA-200 family members and ZEB2 are associated with brain metastasis in gastric adenocarcinoma
Yang-Ki Minn, Da Hye Lee, Woo Jin Hyung, Ji Eun Kim, Junjeong Choi, Seung-Ho Yang, Hotaek Song, Beom Jin Lim, Se Hoon Kim
Pages: 2403-2410 Published online on: 26 September 2014
Article
Fully human VEGFR2 monoclonal antibody BC001 attenuates tumor angiogenesis and inhibits tumor growth Corrigendum in /10.3892/ijo.2023.5583
Zi-Xue Xuan, Lin-Na Li, Qi Zhang, Cheng-Wang Xu, De-Xuan Yang, Ye Yuan, Ying-Hong An, Shan-Shan Wang, Xiao-Wen Li, Shou-Jun Yuan
Pages: 2411-2420 Published online on: 01 October 2014
Article
A potential regulatory loop between Lin28B:miR‑212 in androgen-independent prostate cancer
Emma Borrego-Diaz, Benjamin C. Powers, Vugar Azizov, Scott Lovell, Ruben Reyes, Bradley Chapman, Ossama Tawfik, Douglas McGregor, Francisco J. Diaz, Xinkun Wang, Peter Van Veldhuizen
Pages: 2421-2429 Published online on: 09 September 2014
Article
P-Akt/miR‑200 signaling regulates epithelial-mesenchymal transition, migration and invasion in circulating gastric tumor cells
Dandan Yuan, Hongwei Xia, Yuchen Zhang, Liang Chen, Weibing Leng, Tie Chen, Qingjuan Chen, Qiulin Tang, Xianming Mo, Ming Liu, Feng Bi
Pages: 2430-2438 Published online on: 09 September 2014
Article
Paclitaxel in combination with cetuximab exerts antitumor effect by suppressing NF-κB activity in human oral squamous cell carcinoma cell lines
Koji Harada, Tarannum Ferdous, Hiroaki Kobayashi, Yoshiya Ueyama
Pages: 2439-2445 Published online on: 17 September 2014
Article
Bispecific anti‑CD3 x anti‑HER2 antibody mediates T cell cytolytic activity to HER2‑positive colorectal cancer in vitro and in vivo
Huamin Han, Juan Ma, Keming Zhang, Wei Li, Changzhen Liu, Yu Zhang, Ganlin Zhang, Pan Ma, Lei Wang, Ge Zhang, Hua Tao, Bin Gao
Pages: 2446-2454 Published online on: 18 September 2014
Article
Monoclonal antibody G250 targeting CA Ⅸ: Binding specificity, internalization and therapeutic effects in a non‑renal cancer model
Miriam Zatovicova, Lenka Jelenska, Alzbeta Hulikova, Peter Ditte, Zuzana Ditte, Lucia Csaderova, Eliska Svastova, Wolfgang Schmalix, Volker Boettger, Paul Bevan, Jaromir Pastorek, Silvia Pastorekova
Pages: 2455-2467 Published online on: 17 September 2014
Article
Visualization and characterization of cancer stem-like cells in cervical cancer
Kazuhiko Hayashi, Keisuke Tamari, Hideshi Ishii, Masamitsu Konno, Naohiro Nishida, Koichi Kawamoto, Jun Koseki, Takahito Fukusumi, Yoshihiro Kano, Shimpei Nishikawa, Masaaki Miyo, Kozo Noguchi, Hisataka Ogawa, Atsushi Hamabe, Yuji Seo, Yuichiro Doki, Masaki Mori, Kazuhiko Ogawa
Pages: 2468-2474 Published online on: 24 September 2014
Article
Possible contribution of aminopeptidase N (APN/CD13) to migration and invasion of human osteosarcoma cell lines
Wenqing Liang, Bo Gao, Guojian Xu, Dong Weng, Minghua Xie, Yu Qian
Pages: 2475-2485 Published online on: 22 September 2014
Article
miR‑494 is an independent prognostic factor and promotes cell migration and invasion in colorectal cancer by directly targeting PTEN
Hai‑Bing Sun, Xi Chen, Hong Ji, Tao Wu, Hong‑Wei Lu, Yan Zhang, Hua Li, Yi‑Ming Li
Pages: 2486-2494 Published online on: 22 September 2014
Article
Alterations in the serum proteome profile during the development of ovarian cancer
Liping Sun, Li Li, Zhao Li, Shuhui Hong, Qifeng Yang, Xun Qu, Beihua Kong
Pages: 2495-2501 Published online on: 25 September 2014
Article
CCR7 regulates cell migration and invasion through MAPKs in metastatic squamous cell carcinoma of head and neck
Fa‑Yu Liu, Jawad Safdar, Zhen‑Ning Li, Qi‑Gen Fang, Xu Zhang, Zhong‑Fei Xu, Chang‑Fu Sun
Pages: 2502-2510 Published online on: 25 September 2014
Article
Methylation‑associated inactivation of LATS1 and its effect on demethylation or overexpression on YAP and cell biological function in human renal cell carcinoma
Ke‑Hong Chen, Jiang He, De‑Lin Wang, Jian‑Jia Cao, Mei‑Cai Li, Xiu‑Min Zhao, Xia Sheng, Wen‑Bin Li, Wu‑Jiang Liu
Pages: 2511-2521 Published online on: 30 September 2014
Article
Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2
Megumi Maeda, Ying Chen, Hiroaki Hayashi, Naoko Kumagai-Takei, Hidenori Matsuzaki, Suni Lee, Yasumitsu Nishimura, Takemi Otsuki
Pages: 2522-2532 Published online on: 29 September 2014
Article
Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9
Ki Rim Lee, Jong Seok Lee, Jeong Eun Song, Suk Jin Ha, Eock Kee Hong
Pages: 2533-2540 Published online on: 30 September 2014
Article
HP1β suppresses metastasis of human cancer cells by decreasing the expression and activation of MMP2
Sang Ah Yi, Hyun‑Wook Ryu, Dong Hoon Lee, Jeung‑Whan Han, So Hee Kwon
Pages: 2541-2548 Published online on: 09 September 2014
Article
Identification of a metabolic and canonical biomarker signature in Mexican HR+/HER2-, triple positive and triple-negative breast cancer patients
Silvia Cecilia Pacheco-Velázquez, Juan Carlos Gallardo-Pérez, José Luis Aguilar-Ponce, Patricia Villarreal, Luz Ruiz-Godoy, Manuel Pérez-Sánchez, Alvaro Marín-Hernández, Erika Ruiz-García, Abelardo Meneses-García, Rafael Moreno-Sánchez, Sara Rodríguez-Enríquez
Pages: 2549-2559 Published online on: 25 September 2014
Article
Knockdown of β3GnT8 reverses 5‑fluorouracil resistance in human colorectal cancer cells via inhibition the biosynthesis of polylactosamine‑type N‑glycans
Li Shen, Meiyun Yu, Xu Xu, Liping Gao, Jianlong Ni, Zhiguo Luo, Shiliang Wu
Pages: 2560-2568 Published online on: 25 September 2014
Article
Protective effects of deep sea water against doxorubicin‑induced cardiotoxicity in H9c2 cardiac muscle cells
Do‑Hyung Lee, Soyoung Kim, Kyung‑Soo Nam
Pages: 2569-2575 Published online on: 22 September 2014
Article
Epigenetic silencing of miRNA‑9 is correlated with promoter‑proximal CpG island hypermethylation in gastric cancer in vitro and in vivo
Yan Li, Zhong Xu, Bo Li, Zhengzheng Zhang, Hongchun Luo, Yuanhu Wang, Zhizhong Lu, Xiaoling Wu
Pages: 2576-2586 Published online on: 23 September 2014
Article
Pharmacological suppression of the Ras/MAPK pathway in thyroid carcinoma cells can provoke opposite effects on cell migration and proliferation: The appearance of yin-yang effects and the need of combinatorial treatments
Alexander Glassmann, Jochen Winter, Dominik Kraus, Nadine Veit, Rainer Probstmeier
Pages: 2587-2595 Published online on: 23 September 2014
Article
DUSP28 contributes to human hepatocellular carcinoma via regulation of the p38 MAPK signaling
Dong Wang, Sheng Han, Rui Peng, Chenyu Jiao, Xing Wang, Zeguang Han, Xiangcheng Li
Pages: 2596-2604 Published online on: 16 September 2014
Correction
