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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2004 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review)

Gangduo Wang, Eddie Reed, Qingdi Q. Li
Pages: 955-965
Published online on: 01 November 2004

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Article

Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or non-invasive lesions

Manabu Matsumoto, Yuji Ohtsuki, Kenji Ochii, Yasushi Seike, Norihiro Iseda, Toyokazu Sasaki, Yuhei Okada, Atsushi Kurabayashi, Mutsuo Furihata
Pages: 967-971
Published online on: 01 November 2004

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Dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine S-1 may be effective against peritoneal dissemination in gastric cancer

Shigehito Yamagata, Bunzo Nakata, Kosei Hirakawa
Pages: 973-978
Published online on: 01 November 2004

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Loss of estrogen receptor β expression at cancer front correlates with tumor progression and poor prognosis of gallbladder cancer

Kenji Sumi, Satoru Matsuyama, Yoshihiko Kitajima, Kohji Miyazaki
Pages: 979-984
Published online on: 01 November 2004

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Article

Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality

Reiko Ito, Hirofumi Nakayama, Kazuhiro Yoshida, Noriko Oda, Wataru Yasui
Pages: 985-990
Published online on: 01 November 2004

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Article

Orthotopically implanted SCID mouse model of human lung cancer suitable for investigating metastatic potential and anticancer drug effects

Kazuya Kondo, Haruhiko Fujino, Takanori Miyoshi, Hisashi Ishikura, Shoji Sakiyama, Yasumasa Monden
Pages: 991-999
Published online on: 01 November 2004

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Expression of human kallikrein 7 (hK7/SCCE) and its inhibitor antileukoprotease (ALP/SLPI) in uterine endocervical glands and in cervical adenocarcinomas

Xiurong Tian, Kazushi Shigemasa, Eiji Hirata, Lijun Gu, Yoshimi Uebaba, Nobutaka Nagai, Timothy J. O'Brien, Koso Ohama
Pages: 1001-1006
Published online on: 01 November 2004

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Reduced expression of endothelial and inducible nitric oxide synthase in a multidrug resistant variant of the MCF-7 human breast cancer cell line

M. Lahiri, J. H.J. Martin
Pages: 1007-1011
Published online on: 01 November 2004

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Article

Protease-activating-receptor-2 is frequently expressed in papillary adenocarcinoma of the gallbladder

Kohei Shibata, Kazuhiro Yada, Toshifumi Matsumoto, Atsushi Sasaki, Masayuki Ohta, Seigo Kitano
Pages: 1013-1016
Published online on: 01 November 2004

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Article

Hepatocyte growth factor and c-Met immunoreactivity are associated with metastasis in high grade salivary gland carcinoma

Keiichi Tsukinoki, Masanori Yasuda, Yusuke Mori, Shigeyuki Asano, Hiroyuki Naito, Yoshihide Ota, R. Yoshiyuki Osamura, Yoshihisa Watanabe
Pages: 1017-1021
Published online on: 01 November 2004

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Article

Reversal of multidrug-resistance using Valspodar® (PSC 833) and doxorubicin in osteosarcoma

E. Cagliero, R. Ferracini, E. Morello, K. Scotlandi, M. C. Manara, P. Buracco, A. Comandone, R. Baroetto Parisi, N. Baldini
Pages: 1023-1031
Published online on: 01 November 2004

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Single nucleotide polymorphism in the hypoxia-inducible factor-1α gene in colorectal carcinoma

Toshio Kuwai, Yasuhiko Kitadai, Shinji Tanaka, Tsuyoshi Kuroda, Takehiko Ochiumi, Shunji Matsumura, Naohide Oue, Wataru Yasui, Mika Kaneyasu, Keiji Tanimoto, Masahiko Nishiyama, Kazuaki Chayama
Pages: 1033-1037
Published online on: 01 November 2004

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Article

Phosphorylation state of tumor-suppressor gene p53 product overexpressed in skin tumors

Manabu Matsumoto, Mutsuo Furihata, Atsushi Kurabayashi, Yuji Ohtsuki
Pages: 1039-1043
Published online on: 01 November 2004

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Humoral response to p53 is associated with conserved domains II and IV mutations in human colorectal cancer: A case-control study in Taiwan

Chi-Ming Wu, Reiping Tang, Jim-Ray Chen, Meng-Chih Wu, Huei-Tzu Chien, Chung Rong Changchien, Ling-Ling Hsieh
Pages: 1045-1051
Published online on: 01 November 2004

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Article

Small cell lung cancer cells express EGFR and tyrosine phosphorylation of EGFR is inhibited by gefitinib (‘Iressa’, ZD1839)

Sachie Tanno, Yoshinobu Ohsaki, Kyoko Nakanishi, Eri Toyoshima, Kenjiro Kikuchi
Pages: 1053-1057
Published online on: 01 November 2004

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Article

A multi-center, late phase II clinical trial of Genexol® (paclitaxel) and cisplatin for patients with advanced gastric cancer

Sook Ryun Park, Do-Youn Oh, Dong-Wan Kim, Tae-You Kim, Dae Seog Heo, Yung-Jue Bang, Noe Kyeong Kim, Won Ki Kang, Heung-Tae Kim, Seock-Ah Im, Jae-Hong Suh, Hark-Kyun Kim, Hoon-Kyo Kim
Pages: 1059-1064
Published online on: 01 November 2004

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Article

The effectiveness of artificial neural networks in evaluating treatment plans for patients requiring external beam radiotherapy

Bo Lennernäs, Dan Sandberg, Per Albertsson, Åke Silén, Ulf Isacsson
Pages: 1065-1070
Published online on: 01 November 2004

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Article

Involvement of 90K/Mac-2 binding protein in cancer metastases by increased cellular adhesiveness in lung cancer

Yoshitomo Ozaki, Keiichi Kontani, Koji Teramoto, Takuya Fujita, Noriaki Tezuka, Satoru Sawai, Toshinaga Maeda, Hiroyoshi Watanabe, Shozo Fujino, Tohru Asai, Iwao Ohkubo
Pages: 1071-1077
Published online on: 01 November 2004

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Dietary effects of conjugated docosahexaenoic acid on N-methyl-N-nitrosourea-induced mammary carcinogenesis in female Sprague-Dawley rats

Naoyuki Danbara, Norihisa Uehara, Nobuaki Shikata, Hideho Takada, Takahiko Hada, Airo Tsubura
Pages: 1079-1085
Published online on: 01 November 2004

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Article

Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas

Takaya Kobatake, Masaaki Yano, Shinichi Toyooka, Kazunori Tsukuda, Hideaki Dote, Takefumi Kikuchi, Minoru Toyota, Mamoru Ouchida, Motoi Aoe, Hiroshi Date, Harvey I. Pass, Hiroyoshi Doihara, Nobuyoshi Shimizu
Pages: 1087-1092
Published online on: 01 November 2004

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Article

Epstein-Barr virus-associated gastric carcinoma in Papua New Guinea

Jacob Morewaya, Chihaya Koriyama, Suminori Akiba, Ding Shan, Tetsuhiko Itoh, Yoshito Eizuru
Pages: 1093-1098
Published online on: 01 November 2004

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Article

Infrequent somatic mutations of the ICAT gene in various human cancers with frequent 1p-LOH and/or abnormal nuclear accumulation of β-catenin

Mitsuho Imai, Tsutomu Nakamura, Tetsu Akiyama, Akira Horii
Pages: 1099-1103
Published online on: 01 November 2004

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Article

Complementation of temperature tolerance by rat Rgl-1 recessive oncogene in the absence of Saccharomyces cerevisiae Sop genes

Yu-Kyung Kim, Yong-Soo Kim, Hyung-Min Chung, Kwang-Hyun Baek
Pages: 1105-1108
Published online on: 01 November 2004

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Article

Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid

Ulf Vogt, Krzysztof P. Bielawski, Ulrich Bosse, Claus M. Schlotter
Pages: 1109-1114
Published online on: 01 November 2004

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Article

Impact of cytidine deaminase activity on intrinsic resistance to cytarabine in carcinoma cells

Takuya Ohta, Hiroki Hori, Masahiro Ogawa, Masazumi Miyahara, Hajime Kawasaki, Norihisa Taniguchi, Yoshihiro Komada
Pages: 1115-1120
Published online on: 01 November 2004

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Article

Concurrent preoperative chemoradiotherapy for stage III or IV esophageal squamous carcinoma

Yoshiaki Osaka, Yu Takagi, Akihiko Tsuchida, Sumito Hoshino, Shingo Tachibana, Motoo Shinohara, Tatsuya Aoki
Pages: 1121-1126
Published online on: 01 November 2004

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Article

Predicting recurrence and metastasis of stage II/Dukes' B colorectal cancer without lymph node metastasis

Masaya Mukai, Shinkichi Sato, Takayuki Tajima, Hiromi Ninomiya, Tomomi Kimura, Nobukazu Komatsu, Hisao Nakasaki, Hiroyasu Makuuchi
Pages: 1127-1130
Published online on: 01 November 2004

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Article

Deregulation of p73 isoform equilibrium in benign prostate hyperplasia and prostate cancer

Demetrios A. Arvanitis, Emmanouel Lianos, Nikolaos Soulitzis, Demetrios Delakas, Demetrios A. Spandidos
Pages: 1131-1137
Published online on: 01 November 2004

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Article

Adenosine triphosphate (ATP) enhances the antitumor effect of etoposide (VP16) in lung cancer cells

Yoshihiro Hatta, Miki Takahashi, Yuko Enomoto, Noriaki Takahashi, Umihiko Sawada, Takashi Horie
Pages: 1139-1142
Published online on: 01 November 2004

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Article

Prognostic value of cell cycle regulator molecules in surgically resected stage I and II breast cancer

Maria Giselle Peters, Maria Del Carmen C Vidal, Liliana Giménez, Laura Mauro, Eduardo Armanasco, Carlos Cresta, Elisa Bal De Kier Joffé, Lydia Puricelli
Pages: 1143-1150
Published online on: 01 November 2004

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

PI3Kδ inhibitor YY‑20394 is effective alone or in combination with Bcl‑2 inhibitor ABT199 in acute myeloid leukemia cells

Yinghua Geng, Lili Zhou, Yan Lou, Jiaqi Chen, Qi Liu, Ji Shen, Yanli Yang, Wenjuan Wu
Article Number: 148
Published online on: 17 June 2026

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Schisandrin B exhibits anti‑proliferative effects by inducing ferroptosis in pancreatic cancer

Fengjin Li, Jiacai Fu, Xiaowei Lin, Yanting Liu, Lu Yang, Yuxin Li, Tieli Peng, Ling Qi
Article Number: 147
Published online on: 16 June 2026

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Review

Research advances on DKK1 in head and neck squamous cell carcinoma: Linking molecular mechanisms to clinical applications (Review)

Xiaoqian Zhu, Liwei Hong, Weihan Chen, Junjuan Tan, Juju Zhou, Lingya Yang, Yonglin Liu, Tiantian Zhai, Kai Chen
Article Number: 146
Published online on: 16 June 2026

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A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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