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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2008 Volume 19 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Highlighting the immunohistochemical profile of melanocytomas (Review)

Pascale Quatresooz, Claudine Piérard-Franchimont, Gérald E. Piérard
Pages: 1367-1372
Published online on: 01 June 2008

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Article

Tumor risk assessment by means of immunocytochemical detection of early pre-malignant changes in buccal smears

Marc M. Bloching, Hannah Soulsby, Andreas Naumann, Wolfram Aust, Daniel Merkel, Theresa Braun, Ramin Naim
Pages: 1373-1379
Published online on: 01 June 2008

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Article

ERAP140/Nbla10993 is a novel favorable prognostic indicator for neuroblastoma induced in response to retinoic acid

Hiroshi Arai, Toshinori Ozaki, Hidetaka Niizuma, Yohko Nakamura, Miki Ohira, Kunio Takano, Masahiko Matsumoto, Akira Nakagawara
Pages: 1381-1388
Published online on: 01 June 2008

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Article

New radiosensitization treatment (KORTUC I) using hydrogen peroxide solution-soaked gauze bolus for unresectable and superficially exposed neoplasms

Yasuhiro Ogawa, Hironobu Ue, Kazuhiro Tsuzuki, Michiko Tadokoro, Kana Miyatake, Toshikazu Sasaki, Norikazu Yokota, Norihiko Hamada, Shinji Kariya, Jiro Hitomi, Akihito Nishioka, Kimiko Nakajima, Mitsunori Ikeda, Shigetoshi Sano, Taisuke Inomata
Pages: 1389-1394
Published online on: 01 June 2008

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Article

Efficacy of oncolytic reovirus against human breast cancer cells

Yoko Hata, Tsuyoshi Etoh, Masafumi Inomata, Norio Shiraishi, Akira Nishizono, Seigo Kitano
Pages: 1395-1398
Published online on: 01 June 2008

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Article

A fraction of methylene chloride from Geum japonicum Thunberg inhibits tumor metastatic and angiogenic potential

Jin-Chul Heo, Minsik Son, Sang-Uk Woo, Mi-Ae Kweon, Eun Kyung Yoon, Hee Kyung Lee, Won-Sik Choi, Kang-Jin Cho, Sang-Han Lee
Pages: 1399-1403
Published online on: 01 June 2008

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Decreased expression of the thyroid-stimulating hormone receptor in poorly-differentiated carcinoma of the thyroid

Hirofumi Matsumoto, Atsuhiko Sakamoto, Masachika Fujiwara, Yukiko Yano, Yukiko Shishido-Hara, Yasunori Fujioka, Hiroshi Kamma
Pages: 1405-1411
Published online on: 01 June 2008

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Comparison of Epstein-Barr virus genotypes and clinicohistopathological features of nasopharyngeal carcinoma between Guilin, China and Fukuoka, Japan

Yingqiong Zhou, Kazuki Nabeshima, Kaori Koga, Mikiko Aoki, Hiroyuki Hayashi, Makoto Hamasaki, Hiroshi Iwasaki
Pages: 1413-1420
Published online on: 01 June 2008

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Article

Loss of CYLD might be associated with development of salivary gland tumors

Masakatsu Fukuda, Miki Hiroi, Seiji Suzuki, Yoshihiro Ohmori, Hideaki Sakashita
Pages: 1421-1427
Published online on: 01 June 2008

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Article

PTEN expression and methylation status in oral squamous cell carcinoma

Yoshinori Kurasawa, Masashi Shiiba, Megumi Nakamura, Kazuaki Fushimi, Takashi Ishigami, Hiroki Bukawa, Hidetaka Yokoe, Katsuhiro Uzawa, Hideki Tanzawa
Pages: 1429-1434
Published online on: 01 June 2008

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Comparison of histologic subtype and growth pattern in intraductal papillary-mucinous carcinoma of the pancreas

Yuichi Sanada, Satoko Kunita, Kazuhiro Yoshida
Pages: 1435-1443
Published online on: 01 June 2008

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Article

HER-2 peptides p776 and F7, N-terminal-linked with Ii-Key tetramer (LRMK) help the proliferation of E75-TCR+ cells: The dependency of help on the side chains of LRMK-extended peptide pointed towards the T cell receptor

Yufeng Li, Satoshi Ishiyama, Satoko Matsueda, Naotake Tsuda, Constantin G. Ioannides
Pages: 1445-1452
Published online on: 01 June 2008

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Article

HLA-B gene participates in the NF-κB signal pathway partly by regulating S100A8 in the laryngeal carcinoma cell line Hep2

Yan Guo, Jia Liu, Zhenming Xu, Kailai Sun, Weineng Fu
Pages: 1453-1459
Published online on: 01 June 2008

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Article

Association between the expression of chemokine receptors CCR7 and CXCR3, and lymph node metastatic potential in lung adenocarcinoma

Shinichi Maekawa, Akinori Iwasaki, Takayuki Shirakusa, Takehito Kawakami, Jun Yanagisawa, Toshihiro Tanaka, Hirotomo Shibaguchi, Testushi Kinugasa, Motomu Kuroki, Masahide Kuroki
Pages: 1461-1468
Published online on: 01 June 2008

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Evidence of chromosomal alterations in pure usual ductal hyperplasia as a breast carcinoma precursor

Shu Xu, Bing Wei, Hongying Zhang, Mingxia Qing, Hong Bu
Pages: 1469-1475
Published online on: 01 June 2008

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Article

The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation

Uta Drebber, Stephan E. Baldus, Britt Nolden, Guido Grass, Elfriede Bollschweiler, Hans P. Dienes, Arnulf H. Hölscher, Stefan P. Mönig
Pages: 1477-1483
Published online on: 01 June 2008

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Article

The cellular localization of autotaxin impacts on its biological functions in human thyroid carcinoma cells

Anja Seifert, Thomas Klonisch, Jens Wulfaenger, Friedrich Haag, Henning Dralle, Jürgen Langner, Cuong Hoang-Vu, Astrid Kehlen
Pages: 1485-1491
Published online on: 01 June 2008

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Article

Anticancer effect of SN-38 on colon cancer cell lines with different metastatic potential

Åsa Wallin, Joar Svanvik, Birgitta Holmlund, Lillianne Ferreud, Xiao-Feng Sun
Pages: 1493-1498
Published online on: 01 June 2008

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Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck

Christiane Skoda, Boban M. Erovic, Volker Wachek, Laurenz Vormittag, Fritz Wrba, Helga Martinek, Gregor Heiduschka, Philipp Kloimstein, Edgar Selzer, Dietmar Thurnher
Pages: 1499-1503
Published online on: 01 June 2008

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Contribution of mutations in ATM to breast cancer development in the Czech population

Jana Soukupova, Pavel Dundr, Zdenek Kleibl, Petr Pohlreich
Pages: 1505-1510
Published online on: 01 June 2008

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Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7

Jeremy Roy, Brenna Vantol, Elizabeth A. Cowley, Jonathan Blay, Paul Linsdell
Pages: 1511-1516
Published online on: 01 June 2008

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Article

CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo

I. Hubeek, E. M. Comijn, C. L. Van der Wilt, R. L. Merriman, J. M. Padron, G. J.L. Kaspers, G. J. Peters
Pages: 1517-1523
Published online on: 01 June 2008

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Article

A single institutional experience of surgically resected thymic epithelial tumors over 10 years - Clinical outcomes and clinicopathologic features

Beom Kyung Kim, Byoung Chul Cho, Hye Jin Choi, Joo Hyuk Sohn, Moo Suk Park, Joon Chang, Se Kyu Kim, Dae Joon Kim, Kyung Young Chung, Chang Geol Lee, Joo Hang Kim, Nae Choon Yoo
Pages: 1525-1531
Published online on: 01 June 2008

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Article

Decorin suppresses lung metastases of murine osteosarcoma

Ken Shintani, Akihiko Matsumine, Katsuyuki Kusuzaki, Joji Morikawa, Takao Matsubara, Toru Wakabayashi, Kentaro Araki, Haruhiko Satonaka, Hiroki Wakabayashi, Takahiro Iino, Atsumasa Uchida
Pages: 1533-1539
Published online on: 01 June 2008

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Article

Mutations of epidermal growth factor receptor in colon cancer indicate susceptibility or resistance to gefitinib

Xiang Zhang, Hisashi Nagahara, Koshi Mimori, Hiroshi Inoue, Tetsuji Sawada, Masaichi Ohira, Kosei Hirakawa, Masaki Mori
Pages: 1541-1544
Published online on: 01 June 2008

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Article

Impact of mitochondrial DNA on hypoxic radiation sensitivity in human fibroblast cells and osteosarcoma cell lines

Hideya Yamazaki, Ken Yoshida, Yasuo Yoshioka, Fumiaki Isohashi, Shuji Ozeki, Masahiko Koizumi, Makoto Yoneda, Takehiro Inoue
Pages: 1545-1549
Published online on: 01 June 2008

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Article

A phase II multicenter trial of concurrent chemoradiotherapy with weekly nedaplatin in advanced uterine cervical carcinoma: Tohoku Gynecologic Cancer Unit Study

Yoshihito Yokoyama, Tadao Takano, Kenji Nakahara, Tadahiro Shoji, Hirokazu Sato, Hidekazu Yamada, Nobuo Yaegashi, Kunihiro Okamura, Hirohisa Kurachi, Toru Sugiyama, Toshinobu Tanaka, Akira Sato, Toru Tase, Hideki Mizunuma
Pages: 1551-1556
Published online on: 01 June 2008

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Article

Expression of epiregulin, a novel epidermal growth factor ligand associated with prognosis in human oral squamous cell carcinomas

Hideo Shigeishi, Koichiro Higashikawa, Misato Hiraoka, Shinichi Fujimoto, Yoshitsugu Mitani, Kouji Ohta, Masaaki Takechi, Nobuyuki Kamata
Pages: 1557-1564
Published online on: 01 June 2008

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Article

Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers

Jeevan K. Prasain, Kenneth Jones, Ray Moore, Stephen Barnes, Marge Leahy, Robin Roderick, M. Margaret Juliana, Clinton J. Grubbs
Pages: 1565-1570
Published online on: 01 June 2008

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Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancer

Takao Ide, Yoshihiko Kitajima, Kazuma Ohtaka, Mayumi Mitsuno, Yuji Nakafusa, Kohji Miyazaki
Pages: 1571-1576
Published online on: 01 June 2008

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Article

Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis

Hoesook Yoo, Hwa Jun Cha, Joonyoung Lee, Eun-Ok Yu, Seunghee Bae, Jin Hyuk Jung, Insook Sohn, Su-Jae Lee, Kwang-Hee Yang, Sang-Hyeok Woo, Sung-Keum Seo, In-Chul Park, Chong Soon Kim, Young-Woo Jin, Sung K. Ahn
Pages: 1577-1582
Published online on: 01 June 2008

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Article

Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice

Xi Zheng, Xiao-Xing Cui, Mou-Tuan Huang, Yue Liu, Weichung Joe Shih, Yong Lin, Yao Ping Lu, George C. Wagner, Allan H. Conney
Pages: 1583-1588
Published online on: 01 June 2008

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Article

A study on anti-tumor immunity induced by gene-modified melanoma B16 cells

Lijuan Fang, Kemin Wang, Xia Liu, Leilei Zhang, Xingqian Zhang, Li Qian, Jian Lu, Guanxiang Qian, Shengfang Ge
Pages: 1589-1595
Published online on: 01 June 2008

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Article

A cyclic peptide derived from α-fetoprotein inhibits the proliferative effects of the epidermal growth factor and estradiol in MCF7 cells

Cristian Torres, Elmer Antileo, Maráa José Epuñán, Ana María Pino, Luis Emilio Valladares, Walter Daniel Sierralta
Pages: 1597-1603
Published online on: 01 June 2008

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Article

Telomere length and radiosensitivity in human fibroblast clones immortalized by ectopic telomerase expression

Samantha Zongaro, Annalisa Verri, Elena Giulotto, Chiara Mondello
Pages: 1605-1609
Published online on: 01 June 2008

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Article

Apoptosis in B-CLL: The relationship between higher ex vivo spontaneous apoptosis before treatment in III-IV Rai stage patients and poor outcome

Malgorzata Sieklucka, Piotr Pozarowski, Agnieszka Bojarska-Junak, Iwona Hus, Anna Dmoszynska, Jacek Rolinski
Pages: 1611-1620
Published online on: 01 June 2008

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Article

Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: Inhibition of ribonucleotide reductase activity

Philipp Saiko, Michael Pemberger, Zsuzsanna Horvath, Ivo Savinc, Michael Grusch, Norbert Handler, Thomas Erker, Walter Jaeger, Monika Fritzer-Szekeres, Thomas Szekeres
Pages: 1621-1626
Published online on: 01 June 2008

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Article

Progestins regulate genes that can elicit both proliferative and antiproliferative effects in breast cancer cells

Sami Purmonen, Tommi Manninen, Pasi Pennanen, Timo Ylikomi
Pages: 1627-1634
Published online on: 01 June 2008

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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