Journal Articles
Review
Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (Review)
Rubí Viedma-Rodríguez, Luis Baiza-Gutman, Fabio Salamanca‑Gómez, Mariana Diaz‑Zaragoza, Guadalupe Martínez-Hernández, Ruth Ruiz Esparza‑Garrido, Miguel Angel Velázquez-Flores, Diego Arenas-Aranda
Pages: 3-15 Published online on: 16 May 2014
Article
Timing of cisplatin administration for chemoradiotherapy in transgenic mice bearing lens tumors
Shoji Kaku, Norichika Ushioda, Hiroshi Ishii, Takashi Murakami, Kentaro Takahashi, Yuichiro Nakai, Koichiro Shimoya, Takafumi Nakamura
Pages: 16-22 Published online on: 20 May 2014
Article
Galectin fingerprinting in naso-sinusal diseases
Anaëlle Duray, Thibault De Maesschalck, Christine Decaestecker, Myriam Remmelink, Gilbert Chantrain, Jennifer Neiveyans, Mihaela Horoi, Xavier Leroy, Hans-Joachim Gabius, Sven Saussez
Pages: 23-32 Published online on: 23 May 2014
Article
Identification of a novel HLA-A*02:01-restricted cytotoxic T lymphocyte epitope derived from the EML4-ALK fusion gene
Mayuko Yoshimura, Yoshitaka Tada, Kazuya Ofuzi, Masakazu Yamamoto, Tetsuya Nakatsura
Pages: 33-39 Published online on: 19 May 2014
Article
Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma
Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Kjetil Boye, Sverre Heim
Pages: 40-44 Published online on: 15 May 2014
Article
Role of c-Src activity in the regulation of gastric cancer cell migration
Yun Yang, Zhi-Gang Bai, Jie Yin, Guo-Cong Wu, Zhong-Tao Zhang
Pages: 45-49 Published online on: 15 May 2014
Article
Clinicopathological characteristics and prognostic impact of colorectal cancers with NRAS mutations
Toshiro Ogura, Miho Kakuta, Toshimasa Yatsuoka, Yoji Nishimura, Hirohiko Sakamoto, Kensei Yamaguchi, Minoru Tanabe, Yoichi Tanaka, Kiwamu Akagi
Pages: 50-56 Published online on: 06 May 2014
Article
Impact of genetic profiles on the efficacy of anti-EGFR antibodies in metastatic colorectal cancer with KRAS mutation
Tomokazu Kishiki, Hiroaki Ohnishi, Tadahiko Masaki, Kouki Ohtsuka, Yasuo Ohkura, Jyunji Furuse, Masanori Sugiyama, Takashi Watanabe
Pages: 57-64 Published online on: 15 May 2014
Article
Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells
Koichi Shoji, Jun Teishima, Tetsutaro Hayashi, Shinya Ohara, Wallace L. Mckeehan, Akio Matsubara
Pages: 65-70 Published online on: 20 May 2014
Article
Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways
Eun Jeong Gweon, Song-Ja Kim
Pages: 71-78 Published online on: 16 May 2014
Article
Inhibitor of DNA-binding protein 1 knockdown arrests the growth of colorectal cancer cells and suppresses hepatic metastasis in vivo
Xiaolan Lai, Jinrong Liao, Wansong Lin, Chuanzhong Huang, Jieyu Li, Jizhen Lin, Qiang Chen, Yunbin Ye
Pages: 79-88 Published online on: 08 May 2014
Article
Comparative study of the antitumor activity of Nab-paclitaxel and intraperitoneal solvent-based paclitaxel regarding peritoneal metastasis in gastric cancer
Jun Kinoshita, Sachio Fushida, Tomoya Tsukada, Katsunobu Oyama, Toshihumi Watanabe, Masatoshi Shoji, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Hiroyuki Furukawa, Hironori Hayashi, Keishi Nakamura, Masahumi Inokuchi, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya, Takashi Fujimura, Yashiro Masakazu, Kosei Hirakawa, Tetsuo Ohta
Pages: 89-96 Published online on: 23 May 2014
Article
Global fecal microRNA profiling in the identification of biomarkers for colorectal cancer screening among Asians
Lee Cheng Phua, Xiu Ping Chue, Poh Koon Koh, Peh Yean Cheah, Eric Chun Yong Chan, Han Kiat Ho
Pages: 97-104 Published online on: 16 May 2014
Article
Gastric cancer cell adhesion to laminin enhances acquired chemotherapeutic drug resistance mediated by MGr1-Ag/37LRP
Li Sun, Lili Liu, Xiangqiang Liu, Yafang Wang, Mengbin Li, Liping Yao, Jianjun Yang, Genlin Ji, Changcun Guo, Yanglin Pan, Shuhui Liang, Biaoluo Wang, Jie Ding, Hongwei Zhang, Yongquan Shi
Pages: 105-114 Published online on: 15 May 2014
Article
MicroRNA-223 functions as an oncogene in human colorectal cancer cells
Jufeng Zhang, Xia Luo, Huiming Li, Xupeng Yue, Lin Deng, Yuanyuan Cui, Yanxin Lu
Pages: 115-120 Published online on: 08 May 2014
Article
MMP-2/9-oriented combinations enhance antitumor efficacy of EGFR/HER2-targeting fusion proteins and gemcitabine
Ye Qin, Xiu-Jun Liu, Liang Li, Xu-Jie Liu, Yi Li, Rui‑Juan Gao, Rong-Guang Shao, Yong-Su Zhen
Pages: 121-130 Published online on: 07 May 2014
Article
2'-Hydroxyflavanone inhibits prostate tumor growth through inactivation of AKT/STAT3 signaling and induction of cell apoptosis
Kaijie Wu, Zhongyun Ning, Jiancheng Zhou, Bin Wang, Jinhai Fan, Jianning Zhu, Yang Gao, Xinyang Wang, Jer-Tsong Hsieh, Dalin He
Pages: 131-138 Published online on: 26 May 2014
Article
Interaction of ribosomal protein L22 with casein kinase 2α: A novel mechanism for understanding the biology of non-small cell lung cancer
Mingxia Yang, Haibo Sun, Ji He, Hong Wang, Xiaowei Yu, Lei Ma, Changliang Zhu
Pages: 139-144 Published online on: 15 May 2014
Article
Presence of the minor EGFR T790M mutation is associated with drug-sensitive EGFR mutations in lung adenocarcinoma patients
Shinsuke Hashida, Junichi Soh, Shinichi Toyooka, Tomoaki Tanaka, Masashi Furukawa, Kazuhiko Shien, Hiromasa Yamamoto, Hiroaki Asano, Kazunori Tsukuda, Koichi Hagiwara, Shinichiro Miyoshi
Pages: 145-152 Published online on: 16 May 2014
Article
Establishment of hypoxia induction in an in vivo animal replacement model for experimental evaluation of pancreatic cancer Corrigendum in /10.3892/or.2023.8626
Nathalie Bauer, Li Liu, Ewa Aleksandrowicz, Ingrid Herr
Pages: 153-158 Published online on: 16 May 2014
Article
YKL-40 downregulation is a key factor to overcome temozolomide resistance in a glioblastoma cell line
Yasuto Akiyama, Tadashi Ashizawa, Masaru Komiyama, Haruo Miyata, Chie Oshita, Maho Omiya, Akira Iizuka, Akiko Kume, Takashi Sugino, Nakamasa Hayashi, Koichi Mitsuya, Yoko Nakasu, Ken Yamaguchi
Pages: 159-166 Published online on: 16 May 2014
Article
The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells
Daniela Carlisi, Antonella D'Anneo, Roberta Martinez, Sonia Emanuele, Giuseppina Buttitta, Riccardo Di Fiore, Renza Vento, Giovanni Tesoriere, Marianna Lauricella
Pages: 167-172 Published online on: 23 May 2014
Article
Curcumin suppresses cell proliferation through inhibition of the Wnt/β-catenin signaling pathway in medulloblastoma
Misi He, Yu Li, Li Zhang, Longjiang Li, Yi Shen, Ling Lin, Weiping Zheng, Li Chen, Xiuwu Bian, Ho-Keung Ng, Li Tang
Pages: 173-180 Published online on: 22 May 2014
Article
Increased expression of Lgr5 is associated with chemotherapy resistance in human gastric cancer Corrigendum in /10.3892/or.2019.7120
Hong-Qing Xi, Jian-Xin Cui, Wei-Song Shen, Xiao-Song Wu, Shi‑Bo Bian, Ji-Yang Li, Zhou Song, Bo Wei, Lin Chen
Pages: 181-188 Published online on: 22 May 2014
Article
Overexpression of goosecoid homeobox is associated with chemoresistance and poor prognosis in ovarian carcinoma
Kyong-Won Kang, Mi-Jung Lee, Ji-Ae Song, Ju-Yeon Jeong, Yoo-Kyong Kim, Chan Lee, Tae-Heon Kim, Kyu-Beom Kwak, Ok-Jun Kim, Hee Jung An
Pages: 189-198 Published online on: 20 May 2014
Article
Interferon-λ1 induces G1 phase cell cycle arrest and apoptosis in gastric carcinoma cells in vitro
Zhitao Gao, Moli Zhu, Yaping Wu, Pan Gao, Zhihai Qin, Hui Wang
Pages: 199-204 Published online on: 15 May 2014
Article
Overexpression of SHP2 tyrosine phosphatase promotes the tumorigenesis of breast carcinoma
Zhongqian Hu, Haoshu Fang, Xinyi Wang, Danlei Chen, Zhuo Chen, Siying Wang
Pages: 205-212 Published online on: 20 May 2014
Article
HGF and the regulation of tight junctions in human prostate cancer cells
Tracey A. Martin, Malcolm D. Mason, Wen G. Jiang
Pages: 213-224 Published online on: 26 May 2014
Article
Selective suppression of autocatalytic caspase-3 driven by two-step transcriptional amplified human telomerase reverse transcriptase promoter on ovarian carcinoma growth in vitro and in mice
Yue Song, Xing Xin, Zhijun Xia, Xingyue Zhai, Keng Shen
Pages: 225-234 Published online on: 20 May 2014
Article
Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells
Juan Ma, Li Zhuo Han, He Liang, Chunliu Mi, Hui Shi, Jung Joon Lee, Xuejun Jin
Pages: 235-242 Published online on: 23 May 2014
Article
Knocking down the expression of Aurora-A gene inhibits cell proliferation and induces G2/M phase arrest in human small cell lung cancer cells
Yimin Lu, Yuanhua Liu, Jianzhong Jiang, Zhaoqing Xi, Ning Zhong, Shunbin Shi, Jinzhi Wang, Xiaodong Wei
Pages: 243-249 Published online on: 16 May 2014
Article
Integrated analysis using methylation and gene expression microarrays reveals PDE4C as a prognostic biomarker in human glioma
Zhaoshi Bao, Ying Feng, Hongjun Wang, Chuanbao Zhang, Lihua Sun, Zhuohong Yan, Qingyang Liu, Tianzhu Guo, Mingyang Li, Xue Yang, Chuanlu Jiang, Quangeng Zhang, Tao Jiang
Pages: 250-260 Published online on: 15 May 2014
Article
miR-101, downregulated in retinoblastoma, functions as a tumor suppressor in human retinoblastoma cells by targeting EZH2
Qiong Lei, Fengmei Shen, Jie Wu, Weishan Zhang, Jiahui Wang, Lin Zhang
Pages: 261-269 Published online on: 07 May 2014
Article
Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia
Kirsten Hattermann, Susanne Sebens, Ole Helm, Anne Dorothée Schmitt, Rolf Mentlein, H. Maximilian Mehdorn, Janka Held-Feindt
Pages: 270-276 Published online on: 23 May 2014
Article
Promoter hypermethylation influences the suppressive role of maternally expressed 3, a long non-coding RNA, in the development of epithelial ovarian cancer
Xiujie Sheng, Jianqi Li, Lei Yang, Zhiyi Chen, Qin Zhao, Linyu Tan, Yanqing Zhou, Juan Li
Pages: 277-285 Published online on: 22 May 2014
Article
PinX1 without the G-patch motif suppresses proliferation, induces senescence, but does not inhibit telomerase activity in colorectal cancer SW480 cells
Rui Zhang, Jian Zhao, Xu Wang, Li-Li Wang, Jian Xu, Chun Song
Pages: 286-292 Published online on: 20 May 2014
Article
Caveolin-1 plays a key role in the oleanolic acid-induced apoptosis of HL-60 cells
Wei Ma, Di-Di Wang, Li Li, Yu-Kuan Feng, Hong-Mei Gu, Gui-Ming Zhu, Jin-Hua Piao, Yu Yang, Xu Gao, Peng-Xia Zhang
Pages: 293-301 Published online on: 15 May 2014
Article
β1 integrin modulates tumor growth and apoptosis of human colorectal cancer
Jia Song, Jixiang Zhang, Jing Wang, Zhuo Cao, Jun Wang, Xufeng Guo, Weiguo Dong
Pages: 302-308 Published online on: 07 May 2014
Article
Bioinformatics screening regarding herbal components that targetedly regulate the function of tumour-associated macrophages
Bo Gao, Yingmei Wang, Yan Qiu, Weiliang Xia, Xianzhi Meng, Ming Lu, Weihui Zhang, Xin Qiao, Yingmei Zhang, Dongbo Xue
Pages: 309-317 Published online on: 23 May 2014
Article
Src/caveolin-1-regulated EGFR activation antagonizes TRAIL-induced apoptosis in gastric cancer cells
Ling Xu, Xiujuan Qu, Heming Li, Ce Li, Jing Liu, Huachuan Zheng, Yunpeng Liu
Pages: 318-324 Published online on: 15 May 2014
Article
Compound K-induced apoptosis of human hepatocellular carcinoma MHCC97-H cells in vitro
Zhi-Zhong Zheng, Yan-Lin Ming, Liang-Hua Chen, Guo-Hua Zheng, Shao-Song Liu, Qing-Xi Chen
Pages: 325-331 Published online on: 08 May 2014
Article
Non-essential amino acids attenuate apoptosis of gastric cancer cells induced by glucose starvation
Gang Wang, Lei Dai, Laisheng Luo, Wen Xu, Chenjing Zhang, Yimiao Zhu, Zhongting Chen, Wen Hu, Xiang Xu, Wensheng Pan
Pages: 332-340 Published online on: 21 May 2014
Article
Combination of BIBW2992 and ARQ 197 is effective against erlotinib-resistant human lung cancer cells with the EGFR T790M mutation
Geping Qu, Changting Liu, Baojun Sun, Changxi Zhou, Zhijian Zhang, Peng Wang
Pages: 341-347 Published online on: 15 May 2014
Article
Stromal fibroblasts are predictors of disease-related mortality in esophageal squamous cell carcinoma
Shin Saito, Kazue Morishima, Takashi Ui, Daisuke Matsubara, Tomoko Tamura, Sachiko Oguni, Yoshinori Hosoya, Naohiro Sata, Alan T. Lefor, Yoshikazu Yasuda, Toshiro Niki
Pages: 348-354 Published online on: 23 May 2014
Article
Gallic acid inhibits migration and invasion of SCC‑4 human oral cancer cells through actions of NF‑κB, Ras and matrix metalloproteinase-2 and -9
Chao-Lin Kuo, Kuang-Chi Lai, Yi-Shih Ma, Shu-Wen Weng, Jing-Pin Lin, Jing-Gung Chung
Pages: 355-361 Published online on: 23 May 2014
Article
Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer
Fuqiang Yin, Ling Liu, Xia Liu, Gang Li, Li Zheng, Danrong Li, Qi Wang, Wei Zhang, Li Li
Pages: 362-372 Published online on: 13 May 2014
Article
N-benzyl-N-methyldecan-1-amine, a phenylamine derivative isolated from garlic cloves, induces G2/M phase arrest and apoptosis in U937 human leukemia cells
Jin-Woo Jeong, Sejin Park, Cheol Park, Young-Chae Chang, Dong-Oh Moon, Sung Ok Kim, Gi-Young Kim, Hee-Jae Cha, Heui-Soo Kim, Young-Whan Choi, Wun-Jae Kim, Young Hyun Yoo, Yung Hyun Choi
Pages: 373-381 Published online on: 23 May 2014
Article
Targeted inhibition of mTORC2 prevents osteosarcoma cell migration and promotes apoptosis
Xiaokai Wang, Pinglin Lai, Zhongmin Zhang, Minjun Huang, Liang Wang, Min Yin, Dadi Jin, Rongping Zhou, Xiaochun Bai
Pages: 382-388 Published online on: 15 May 2014
Article
Involvement of HIF-1α activation in the doxorubicin resistance of human osteosarcoma cells
Laura Roncuzzi, Fabia Pancotti, Nicola Baldini
Pages: 389-394 Published online on: 15 May 2014
Article
Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancer
Ze-Hua Wu, Xiao-Liang Wang, Hua-Mei Tang, Tao Jiang, Jian Chen, Su Lu, Guo-Qiang Qiu, Zhi-Hai Peng, Dong-Wang Yan
Pages: 395-402 Published online on: 15 May 2014
Article
Overexpression of ZDHHC14 promotes migration and invasion of scirrhous type gastric cancer
Htoo Zarni Oo, Kazuhiro Sentani, Naoya Sakamoto, Katsuhiro Anami, Yutaka Naito, Naohiro Uraoka, Takashi Oshima, Kazuyoshi Yanagihara, Naohide Oue, Wataru Yasui
Pages: 403-410 Published online on: 06 May 2014
Article
Downregulation of galectin-3 causes a decrease in uPAR levels and inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells
Datong Zheng, Zhenzhen Hu, Fan He, Caijie Gao, Lijian Xu, Han Zou, Zhiwei Wu, Xiuqin Jiang, Jianjun Wang
Pages: 411-418 Published online on: 08 May 2014
Article
Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression
Michel D. Wissing, Tikva Dadon, Eunice Kim, Klaus B. Piontek, Joong S. Shim, Nadine S. Kaelber, Jun O. Liu, Sushant K. Kachhap, Barry D. Nelkin
Pages: 419-424 Published online on: 13 May 2014
Article
Corticotropin-releasing factor induces immune escape of cervical cancer cells by downregulation of NKG2D
Hyunkeun Song, Hyunjin Park, Gabin Park, Yeong Seok Kim, Hyun-Kyung Lee, Dong-Hoon Jin, Hyung-Sik Kang, Dae-Ho Cho, Daeyoung Hur
Pages: 425-430 Published online on: 16 May 2014
Article