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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-October 2002 Volume 9 Issue 5

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Significance of E-cadherin/β-catenin complex and cyclin D1 in breast cancer

Sung-Chul Lim, Mi-Sook Lee
Pages: 915-928
Published online on: 01 September 2002

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Article

Treatment with HER-2 phosphorylation agonists enhance tumor ability to stimulate epitope specific CTL in vitro

Agapito Castilleja, Nancy E. Ward, Richard B. Epstein, Andrzej P. Kudelka, David M. Gershenson, Clay L. Efferson, Catherine A. O'Brian, Constantin G. Ioannides
Pages: 929-935
Published online on: 01 September 2002

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Article

The expression of ERβ protein correlates with vascular endothelial growth factor and its prognostic significance in human breast cancer

X.-F. Wen, Z. Shen, Z.-Z. Shen, M. Nguyen, Z.-M. Shao
Pages: 937-944
Published online on: 01 September 2002

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Article

A comparison of human G-Csf and human Gm-Csf given concurrently with anti-cancer chemotherapy

Arthur J. Weiss, Richard D. Lackman
Pages: 945-950
Published online on: 01 September 2002

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Article

Retinoblastoma-related gene RB2/p130 exons 19-22 are rarely mutated in glioblastomas

P. Gonzalez-Gomez, M. J. Bello, D. Arjona, M. E. Alonso, J. Lomas, J. M. De Campos, J. Vaquero, A. Isla, M. Gutierrez, J. A. Rey
Pages: 951-954
Published online on: 01 September 2002

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Article

Concurrent LOH at multiple loci in human malignant mesothelioma with preferential loss of NF2 gene region

Lea Pylkkanen, Markku Sainio, Tiina Ollikainen, Karin Mattson, Stig Nordling, Olli Carpen, Kaija Linnainmaa, Kirsti Husgafvel-Pursiainen
Pages: 955-959
Published online on: 01 September 2002

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Article

Voltage-gated potassium ion channels in colon cancer

Mansoor Abdul, Naseema Hoosein
Pages: 961-964
Published online on: 01 September 2002

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Article

Protein expression profile of newly diagnosed acute lymphoblastic leukemia in children developing relapses

M. Volm, A. Sauerbrey, F. Zintl, R. Koomagi, T. Efferth
Pages: 965-969
Published online on: 01 September 2002

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Article

Analysis of microsatellite instability in acquired drug-resistance human tumor cell lines

S.-F. Picard, N. Franco, C. Sergent, B. Chauffert, S. Lizard-Nacol
Pages: 971-976
Published online on: 01 September 2002

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Article

Apoptosis-related proteins (Fas, Fas ligand, bcl-2 and p53) in different types of human breast tumors

H. Ben-Hur, E. Mordechay, R. Halperin, P. Gurevich, J. Zandbank, M. Herper, I. Zusman
Pages: 977-980
Published online on: 01 September 2002

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Article

Elevated mia serum levels are predictors of poor prognosis after surgical resection of metastatic malignant melanoma

Markus Guba, Markus Steinbauer, Verena Ruhland, Alexander Schutz, Edward K. Geissler, Matthias Anthuber, Thomas Vogt, Anja Bosserhoff, Karl-Walter Jauch
Pages: 981-984
Published online on: 01 September 2002

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Article

Loss of EphB4 receptor tyrosine kinase protein expression during carcinogenesis of the human breast

Gilles Berclaz, Bettina Flutsch, Hans Jorg Altermatt, Valeria Rohrbach, Valentin Djonov, Andrew Ziemiecki, Ekkehard Dreher, Anne-Catherine Andres
Pages: 985-989
Published online on: 01 September 2002

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Article

A single injection of immature dendritic cells is able to induce antitumour response against a murine colon adenocarcinoma with a low apoptotic index

Ahmad Jalili, Tomasz Stoklosa, Adam Giermasz, Dominika Olszewska, Grzegorz Wilczynski, Marek Jakobisiak, Jakub Golab
Pages: 991-994
Published online on: 01 September 2002

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Article

VEGF-C expression correlates with histological differentiation and metastasis in squamous cell carcinoma of the esophagus

Tsuyoshi Noguchi, Shinsuke Takeno, Tomotaka Shibata, Yuzo Uchida, Shigeo Yokoyama, Wolfram Muller
Pages: 995-999
Published online on: 01 September 2002

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Article

Laparoscopic microwave coagulation therapy for small hepatocellular carcinoma on the liver surface

Hiroshi Okano, Katsuya Shiraki, Hidekazu Inoue, Tomoyuki Kawakita, Masatoshi Deguchi, Kazushi Sugimoto, Takahisa Sakai, Shigeru Ohmori, Kazumoto Murata, Takeshi Nakano
Pages: 1001-1004
Published online on: 01 September 2002

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Article

Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma

Shinji Tanaka, Shinji Nagata, Shiro Oka, Toshio Kuwai, Tadamasa Tamura, Yasuhiko Kitadai, Masaharu Sumii, Masaharu Yoshihara, Ken Haruma, Kazuaki Chayama
Pages: 1005-1008
Published online on: 01 September 2002

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Article

Technetium-99m-tetrofosmin scintigraphy in patients with metastatic soft tissue sarcoma

G. Karanikas, W. J. Kostler, A. Becherer, K. Wiesner, R. Dudczak, M. Krainer, K. Kletter
Pages: 1009-1013
Published online on: 01 September 2002

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Article

Immunohistochemical analysis of DNA mismatch repair protein and O6-methylguanine-DNA methyltransferase in melanoma metastases in relation to clinical response to DTIC-based chemotherapy

Shuhua Ma, Suzanne Egyhazi, Ulrik Ringborg, Johan Hansson
Pages: 1015-1019
Published online on: 01 September 2002

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Article

Paradoxical effects by preoperative oral low-dose tegafur administration in human gastric carcinomas: Enhanced apoptosis and increased intratumoral microvessel density

Eizo Goto, Eiji Okamoto, Hironobu Adachi, Yasuhiko Fukuda, Hisao Ito
Pages: 1021-1026
Published online on: 01 September 2002

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Article

The intraductal component of breast cancer is poorly responsive to neo-adjuvant chemotherapy

W. Wu, H. Kamma, E. Ueno, M. Fujiwara, H. Satoh, H. Hara, T. Yashiro, Y. Aiyoshi
Pages: 1027-1031
Published online on: 01 September 2002

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Article

Tumor dihydropyrimidine dehydrogenase activity in advanced cervical carcinoma

Nobutaka Nagai, Yuko Shiroyama, Takafumi Oshita, Keiji Mukai, Kazushi Shigemasa, Tsuneo Fujii, Yasuhiro Katsube, Shigeru Matsubayashi, Takahiro Murakami, Koso Ohama
Pages: 1033-1040
Published online on: 01 September 2002

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Article

Cytokinetic analysis of cell cycle and sub-phases in MOLT-4 cells by cyclin E + A/DNA multiparameter flow cytometry

Jichao Qin, Deding Tao, Rui Duan, Yan Leng, Manli Shen, Hui Zhou, Yongdong Feng, Chun Gao, Yuan Yu, Qingdi Q. Li, Junbo Hu, Jianping Gong
Pages: 1041-1045
Published online on: 01 September 2002

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Review

Weekly taxanes in metastatic breast cancer (Review)

Matteo Zimatore, Marco Danova, Erasmo Vassallo, Camillo Porta, Maria Catena Macaluso, Loredana Schittone, Alberto Riccardi, Sergio Palmeri
Pages: 1047-1052
Published online on: 01 September 2002

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Article

Breast-conserving surgery following radiation therapy of 50 Gy in Stages I and II carcinoma of the breast: The experience at one institute in Japan

Jun Horiguchi, Yukio Koibuchi, Hiroyuki Takei, Takao Yokoe, Michitaka Yamakawa, Takashi Nakajima, Tetsunari Oyama, Yuichi Iino, Yasuo Morishita
Pages: 1053-1057
Published online on: 01 September 2002

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Article

Influencing factors for recurrence of hepatocellular carcinoma treated with radiofrequency ablation

Norio Horiike, Hideto Iuchi, Tuneyuki Ninomiya, Keiko Kawai, Teru Kumagi, Kojiro Michitaka, Toshikazu Masumoto, Morikazu Onji
Pages: 1059-1062
Published online on: 01 September 2002

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Article

Aldehyde dehydrogenase-2 genotypes and HLA haplotypes in Japanese patients with esophageal cancer

S. Watanabe, K. Sasahara, F. Kinekawa, N. Uchida, T. Masaki, K. Kurokohchi, M. Murota, T. Touge, K. Kawauchi, S. Oda, S. Kuriyama
Pages: 1063-1068
Published online on: 01 September 2002

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Article

Weak enhancing effects of simultaneous ethanol administration on chemically induced rat esophageal tumorigenesis

M. Kaneko, K. Morimura, T. Nishikawa, H. Wanibuchi, H. Osugi, H. Kinoshita, A. Koide, Y. Mori, S. Fukishima
Pages: 1069-1073
Published online on: 01 September 2002

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Article

No residual tumor in a radical prostatectomy specimen after neoadjuvant hormonal therapy for localized prostate cancer

Masanori Noguchi, Shinshi Noda, Osamu Nakashima, Masamichi Kojiro
Pages: 1075-1080
Published online on: 01 September 2002

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Article

Correlation of p53 and cerbB2 expression and hormonal receptor status with clinicopathologic parameters in ductal carcinoma in situ of the breast

P.-H. Tan, K.-L. Chuah, G. Chiang, C.-Y. Wong, F. Dong, B.-H. Bay
Pages: 1081-1086
Published online on: 01 September 2002

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Article

Expression of collagen type II, S100B, S100A2 and osteocalcin in chondroblastoma and chondromyxoid fibroma

Hye-Rim Park, Yong-Koo Park, Kee Taek Jang, K. Krishnan Unni
Pages: 1087-1091
Published online on: 01 September 2002

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Article

Has lung cancer in the elderly different characteristics at presentation?

Maurizio Montella, Cesare Gridelli, Anna Crispo, Francesco Scognamiglio, Pasquale Ruffolo, Tindaro Gatani, Vincenzo Boccia, Paolo Maione, Gabriella Fabbrocini
Pages: 1093-1096
Published online on: 01 September 2002

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Article

Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR

Mark Schrader, Angelika M. Burger, Markus Muller, Hans Krause, Bernd Straub, Gilian L. Smith, Eward S. Newlands, Kurt Miller
Pages: 1097-1105
Published online on: 01 September 2002

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Article

Impact of topotecan-based chemotherapy on the immune system of advanced ovarian cancer patients: An immunophenotypic study

Silvia Ferrari, Bianca Rovati, Lucia Cucca, Claudio Scarabelli, Mauro Presti, Cristina Beccaria, Elena Collova, Camillo Porta, Marco Danova
Pages: 1107-1113
Published online on: 01 September 2002

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Article

Genetic alterations related to lymph node metastasis and peritoneal dissemination in epithelial ovarian cancers

Kenji Umayahara, Fumitaka Numa, Akiko Inokuma, Kotaro Sueoka, Keiko Kawasaki, Hiroshi Hirakawa, Tomoko Emoto, Yuko Sakaguchi, Shugo Nawata, Hidenobu Ogata, Masaru Sakamoto, Katsuhiko Hasumi, Shigeto Kawauchi, Kohsuke Sasaki, Hiroshi Kato
Pages: 1115-1119
Published online on: 01 September 2002

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Article

Quantitative analysis of expression levels of bax, bcl-2, and survivin in cancer cells during cisplatin treatment

Masahide Ikeguchi, Seiichi Nakamura, Nobuaki Kaibara
Pages: 1121-1126
Published online on: 01 September 2002

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Article

Gonadotropin releasing hormone receptor expression in primary breast cancer: Comparison of immunohistochemical, radioligand and Western blot analyses

A. Mangia, S. Tommasi, S. J. Reshkin, G. Simone, B. Stea, F. Schittulli, A. Paradiso
Pages: 1127-1132
Published online on: 01 September 2002

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Article

Quantitative analysis of VEGF-isoforms in head and neck squamous cell carcinoma cell lines: Relation to xenotransplantability and tumour progression in mice

Konstantinos Vlachtsis, Jurgen Brieger, Dong-Wook Kim, Rita Gieringer, Jochem Hast, Jan G. Hengstler, Wolf Mann
Pages: 1133-1138
Published online on: 01 September 2002

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Article

Role of the orphan nuclear receptor RORα in the control of the metastatic behavior of androgen-independent prostate cancer cells

R. M. Moretti, M. Montagnani Marelli, M. Motta, P. Limonta
Pages: 1139-1143
Published online on: 01 September 2002

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

PI3Kδ inhibitor YY‑20394 is effective alone or in combination with Bcl‑2 inhibitor ABT199 in acute myeloid leukemia cells

Yinghua Geng, Lili Zhou, Yan Lou, Jiaqi Chen, Qi Liu, Ji Shen, Yanli Yang, Wenjuan Wu
Article Number: 148
Published online on: 17 June 2026

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Published online on: 16 June 2026

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A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
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Published online on: 10 June 2026

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Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

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Published online on: 04 June 2026

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Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

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Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

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Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

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Published online on: 02 June 2026

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Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
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Published online on: 29 May 2026

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