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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2007 Volume 18 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Early development of histiocytic sarcomas in p53 knockout mice treated with N-bis(2-hydroxypropyl)nitrosamine

Akihiro Hirata, Tetsuya Tsukamoto, Masami Yamamoto, Shinji Takasu, Hiroki Sakai, Hisayo Ban, Tokuma Yanai, Toshiaki Masegi, Lawrence A. Donehower, Masae Tatematsu
Pages: 755-761
Published online on: 01 October 2007

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Article

Chemotherapy in metastatic malignant triton tumor: Report on two cases

N. H. Thoennissen, C. Schliemann, U. Brunnberg, E. Schmidt, A. Staebler, L. Stegger, C. Bremer, C. Schleicher, R. M. Mesters, C. Müller-Tidow, W. E. Berdel
Pages: 763-767
Published online on: 01 October 2007

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Article

Expression profile of class I histone deacetylases in human cancer tissues

Masamune Nakagawa, Yoshinao Oda, Takashi Eguchi, Shin-Ichi Aishima, Takashi Yao, Fumihito Hosoi, Yuji Basaki, Mayumi Ono, Michihiko Kuwano, Masao Tanaka, Masazumi Tsuneyoshi
Pages: 769-774
Published online on: 01 October 2007

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Article

Enhancement of capecitabine efficacy by oxaliplatin in human colorectal and gastric cancer xenografts

Noriaki Sawada, Kumiko Kondoh, Kazushige Mori
Pages: 775-778
Published online on: 01 October 2007

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Article

Rapid genetic diagnosis with transcription-reverse transcription concerted reaction system for peritoneal recurrence and survival in colorectal cancer patients

Tamuro Hayama, Hisae Iinuma, Toshiaki Watanabe
Pages: 779-784
Published online on: 01 October 2007

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Article

Inhibition of tumor growth through suppression of angiogenesis by brain-specific angiogenesis inhibitor 1 gene transfer in murine renal cell carcinoma

Shigetaka Kudo, Ryuichiro Konda, Wataru Obara, Daisuke Kudo, Kenzaburo Tani, Yusuke Nakamura, Tomoaki Fujioka
Pages: 785-791
Published online on: 01 October 2007

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Article

Prognostic value of differential expression of Laminin-5 γ2 in oral squamous cell carcinomas: Correlation with survival

A. Gasparoni, M. Della Casa, L. Milillo, G. Lorenzini, C. Rubini, R. Urso, L. Lo Muzio
Pages: 793-800
Published online on: 01 October 2007

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Article

Combination therapy of interferon-α and 5-fluorouracil inhibits tumor angiogenesis in human hepatocellular carcinoma cells by regulating vascular endothelial growth factor and angiopoietins

Hiroshi Wada, Hiroaki Nagano, Hirofumi Yamamoto, Isao Arai, Hideo Ota, Masato Nakamura, Bazarragchaa Damdinsuren, Takehiro Noda, Shigeru Marubashi, Atsushi Miyamoto, Yutaka Takeda, Koji Umeshita, Yuichiro Doki, Keizo Dono, Shoji Nakamori, Masato Sakon, Morito Monden
Pages: 801-809
Published online on: 01 October 2007

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Article

Ascorbate (vitamin C) induces cell death through the apoptosis-inducing factor in human breast cancer cells

Seung-Woo Hong, Dong-Hoon Jin, Eun-Sil Hahm, Sei-Hyun Yim, Jong-Seok Lim, Keun-Il Kim, Young Yang, Soo-Suk Lee, Jae-Seung Kang, Wang-Jae Lee, Won-Keun Lee, Myeong-Sok Lee
Pages: 811-815
Published online on: 01 October 2007

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Article

Methylation and intratumoural heterogeneity of 14-3-3 σ in oral cancer

Ujjal Kumar Bhawal, Keiichi Tsukinoki, Tomonori Sasahira, Fuyuki Sato, Yusuke Mori, Noriko Muto, Masaru Sugiyama, Hiroki Kuniyasu
Pages: 817-824
Published online on: 01 October 2007

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Article

A peroxisome proliferator-activated receptor γ antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma

Kyung Ryoul Kim, Ha Na Choi, Ho Jin Lee, Hyun A Baek, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Woo Sung Moon
Pages: 825-832
Published online on: 01 October 2007

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Article

Peroxisome proliferator-activated receptor α and γ ligands inhibit the growth of human ovarian cancer

Tatsuhiko Shigeto, Yoshihito Yokoyama, Bing Xin, Hideki Mizunuma
Pages: 833-840
Published online on: 01 October 2007

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Article

Expression of Myc target gene mina53 in subtypes of human lymphoma

Kwesi Teye, Nobuyuki Arima, Yasuhiro Nakamura, Kikuo Sakamoto, Eizaburo Sueoka, Hiroshi Kimura, Makoto Tsuneoka
Pages: 841-848
Published online on: 01 October 2007

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Article

Anti-tumor activity of Gastrodia elata Blume is closely associated with a GTP-Ras-dependent pathway

Jin-Chul Heo, Sang-Uk Woo, MinSik Son, Ja-Young Park, Won-Sik Choi, Kyu-Tae Chang, Sung-Uk Kim, Eun-Kyung Yoon, Yong-Hoon Kim, Heung Mook Shin, Sang-Han Lee
Pages: 849-853
Published online on: 01 October 2007

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Article

Expression of metalloproteinases and their tissue inhibitors in squamous cell laryngeal carcinoma

T. A. Christopoulos, N. Papageorgakopoulou, P. Ravazoula, N. S. Mastronikolis, T. A. Papadas, D. A. Theocharis, D. H. Vynios
Pages: 855-860
Published online on: 01 October 2007

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Article

Boron neuron capture therapy using epithermal neutrons for recurrent cancer in the oral cavity and cervical lymph node metastasis

Yasunori Ariyoshi, Shin-Ichi Miyatake, Yoshihiro Kimura, Takeshi Shimahara, Shinji Kawabata, Kenji Nagata, Minoru Suzuki, Akira Maruhashi, Koji Ono, Masashi Shimahara
Pages: 861-866
Published online on: 01 October 2007

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Article

Tumor suppressor Prdx1 is a prognostic factor in esophageal squamous cell carcinoma patients

Isamu Hoshino, Hisahiro Matsubara, Yasunori Akutsu, Takanori Nishimori, Yasuo Yoneyama, Kentaro Murakami, Haruhito Sakata, Kazuyuki Matsushita, Takenori Ochiai
Pages: 867-871
Published online on: 01 October 2007

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Article

Association of DNA-PK activity and radiation-induced NBS1 foci formation in lymphocytes with clinical malignancy in breast cancer patients

Masanori Someya, Koh-Ichi Sakata, Yoshihisa Matsumoto, Hiroshi Tauchi, Hideaki Narimatsu, Masato Hareyama
Pages: 873-878
Published online on: 01 October 2007

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Article

Expression of retinoid X receptor α is decreased in 3'-methyl-4-dimethylaminoazobenzene-induced hepatocellular carcinoma in rats

Nobuhiro Ando, Masahito Shimizu, Masataka Okuno, Rie Matsushima-Nishiwaki, Hisashi Tsurumi, Takuji Tanaka, Hisataka Moriwaki
Pages: 879-884
Published online on: 01 October 2007

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Article

Reduced expression of TANGO in colon and hepatocellular carcinomas

Stephanie Arndt, Anja K. Bosserhoff
Pages: 885-891
Published online on: 01 October 2007

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Article

The activity of Selol in multidrug-resistant and sensitive human leukemia cells

Piotr Suchocki, Irena Misiewicz, Katarzyna Skupinska, Karolina Waclawek, Zbigniew Fijalek, Teresa Kasprzycka-Guttman
Pages: 893-899
Published online on: 01 October 2007

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Article

Perfusion CT can predict the response to chemoradiation therapy and survival in esophageal squamous cell carcinoma: Initial clinical results

Koichi Hayano, Shinichi Okazumi, Kiyohiko Shuto, Hisahiro Matsubara, Hideaki Shimada, Yoshihiro Nabeya, Toshiki Kazama, Noriyuki Yanagawa, Takenori Ochiai
Pages: 901-908
Published online on: 01 October 2007

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Article

Osteopontin stimulates melanoma growth and lung metastasis through NIK/MEKK1-dependent MMP-9 activation pathways

Hema Rangaswami, Gopal C. Kundu
Pages: 909-915
Published online on: 01 October 2007

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Article

Comparative genomic hybridization, BRAF, RAS, RET, and oligo-array analysis in aneuploid papillary thyroid carcinomas

Raquel Rodrigues, Lúcia Roque, Carla Espadinha, António Pinto, Rita Domingues, Joana Dinis, Ana Catarino, Teresa Pereira, Valeriano Leite
Pages: 917-926
Published online on: 01 October 2007

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Article

The relationship between the down-regulation of DNA-PKcs or Ku70 and the chemosensitization in human cervical carcinoma cell line HeLa

Xiaoyu Tian, Gang Chen, Hui Xing, Danhui Weng, Yunhong Guo, Ding Ma
Pages: 927-932
Published online on: 01 October 2007

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Article

Evaluation of anti-VEGFR-3 specific scFv antibodies as potential therapeutic and diagnostic tools for tumor lymph-angiogenesis

Ann H.M. Zehnder-Fjällman, Cornelia Marty, Cornelia Halin, Alexander Hohn, Roger Schibli, Kurt Ballmer-Hofer, Reto A. Schwendener
Pages: 933-941
Published online on: 01 October 2007

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Article

Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray

Yuefang Liu, Xiaojing Zhu, Jin Zhu, Shibing Liao, Qi Tang, Kaikun Liu, Xiaohong Guan, Jianping Zhang, Zhenqing Feng
Pages: 943-951
Published online on: 01 October 2007

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Article

Expression of transcription factor CREB1 in human breast cancer and its correlation with prognosis

Alok Chhabra, Herman Fernando, Gareth Watkins, Robert E. Mansel, Wen G. Jiang
Pages: 953-958
Published online on: 01 October 2007

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Article

Artificial intelligence for predicting recurrence-free probability of non-invasive high-grade urothelial bladder cell carcinoma

Tommaso Cai, Gloria Conti, Gabriella Nesi, Matteo Lorenzini, Nicola Mondaini, Riccardo Bartoletti
Pages: 959-964
Published online on: 01 October 2007

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Article

Impact of therapeutically induced reactive oxygen species and radical scavenging by α-tocopherol on tumor cell adhesion

Oliver Thews, Christine Lambert, Debra K. Kelleher, Hans K. Biesalski, Peter Vaupel, Juergen Frank
Pages: 965-971
Published online on: 01 October 2007

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Article

Inhibition of Fatty Acid Synthase (FASN) synergistically enhances the efficacy of 5-fluorouracil in breast carcinoma cells

Alejando Vazquez-Martin, Santiago Ropero, Joan Brunet, Ramon Colomer, Javier A. Menendez
Pages: 973-980
Published online on: 01 October 2007

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Article

Expression of ECRG4 is an independent prognostic factor for poor survival in patients with esophageal squamous cell carcinoma

Yoichiro Mori, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Horoki Kurehara, Ryota Mori, Keisuke Tomoda, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 981-985
Published online on: 01 October 2007

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Article

Copper efflux transporter (ATP7B) contributes to the acquisition of cisplatin-resistance in human oral squamous cell lines

Kunio Yoshizawa, Shinichi Nozaki, Hiroko Kitahara, Teruhisa Ohara, Koroku Kato, Shuichi Kawashiri, Etsuhide Yamamoto
Pages: 987-991
Published online on: 01 October 2007

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Article

Analysis of hepatitis C virus-specific CD8+ T-cells with HLA-A*24 tetramers during phlebotomy and interferon therapy for chronic hepatitis C

Kyosuke Kaji, Yasunari Nakamoto, Shuichi Kaneko
Pages: 993-998
Published online on: 01 October 2007

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Article

Effects of the CDK-inhibitor CYC202 on p38 MAPK, ERK1/2 and c-Myc activities in papillomavirus type 16 E6- and E7-transformed human keratinocytes

Ganka N. Atanasova, Antonia R. Isaeva, Nikolai Zhelev, Yves Poumay, Vanyo I. Mitev
Pages: 999-1005
Published online on: 01 October 2007

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Article

Loss of heterozygosity on chromosome 10q23 and mutation of the phosphatase and tensin homolog deleted from chromosome 10 tumor suppressor gene in Korean hepatocellular carcinoma patients

Jei-Jun Bae, Jin-Woo Rho, Tae-Jin Lee, Sung-Su Yun, Hong-Jin Kim, Joon-Hyuk Choi, Daewon Jeong, Byeong-Churl Jang, Tae-Yoon Lee
Pages: 1007-1013
Published online on: 01 October 2007

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Article

Inhibitory effects of retinoic acid and IIF on growth, migration and invasiveness in the U87MG human glioblastoma cell line

A. Papi, G. Bartolini, K. Ammar, F. Guerra, A. M. Ferreri, P. Rocchi, M. Orlandi
Pages: 1015-1021
Published online on: 01 October 2007

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Article

Prognosis of small bowel adenocarcinoma treated with Mayo or Xelox regimen: A matched case-control study from a database of 581 patients with colorectal cancer

Jacob Thomsen Lønborg, Adam Vilmar, David Mård, Søren Astrup Jensen, Jens Benn Sørensen
Pages: 1023-1029
Published online on: 01 October 2007

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Article

Interferon-α-induced apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-dependent and -independent manner

Noriko Yanase, Yuki Kanetaka, Junichiro Mizuguchi
Pages: 1031-1038
Published online on: 01 October 2007

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Article

IFN-α competes with TNF-α for STAT-1α; molecular basis for immune escape of human colon adenocarcinoma COLO 205 cells

Beata Pajak, Arkadiusz Orzechowski
Pages: 1039-1045
Published online on: 01 October 2007

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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