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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2009 Volume 21 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Surfactant protein DNA methylation: A new entrant in the field of lung cancer diagnostics? (Review)

Mudit Vaid, Joanna Floros
Pages: 3-11
Published online on: 01 January 2009

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Article

Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin

Ye Bu, Chunhua Lu, Chunjing Bian, Jinghua Wang, Jing Li, Bin Zhang, Zhenya Li, Gary Brewer, Robert Chunhua Zhao
Pages: 13-17
Published online on: 01 January 2009

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Article

Cripto-1 overexpression is involved in the tumorigenesis of gastric-type and pancreatobiliary-type intraductal papillary mucinous neoplasms of the pancreas

Sung P. Hong, Eun K. Lee, Jeong Y. Park, Tae J. Jeon, Seungmin Bang, Seungwoo Park, Jae B. Chung, Woo J. Lee, Hoguen Kim, Si Y. Song
Pages: 19-24
Published online on: 01 January 2009

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The pro-angiogenic factors stimulated by human papillomavirus type 16 E6 and E7 protein in C33A and human fibroblasts

Ling Xi, Shixuan Wang, Changyu Wang, Qian Xu, Pengcheng Li, Xun Tian, Peng Wu, Wei Wang, Dongrui Deng, Jianfeng Zhou, Ding Ma
Pages: 25-31
Published online on: 01 January 2009

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Article

Overexpression of orotate phosphoribosyl transferase in hormone-refractory prostate cancer

Tomoaki Tanaka, Hidenori Kawashima, Kentaro Matsumura, Tomoko Yamashita-Hosono, Rikio Yoshimura, Katsuyuki Kuratsukuri, Koji Harimoto, Tatsuya Nakatani
Pages: 33-37
Published online on: 01 January 2009

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Article

Quantitative molecular grading of bladder tumours: A tool for objective assessment of the biological potential of urothelial neoplasias

Daniel Bollmann, Magdolna Bollmann, Agnes Bankfalvi, Hildegard Heller, Reinhard Bollmann, Gabor Pajor, Ralf Hildenbrand
Pages: 39-47
Published online on: 01 January 2009

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Article

Prognostic value of MUC4 for mass-forming intrahepatic cholangiocarcinoma after hepatectomy

Chun-Nan Yeh, See-Tong Pang, Ren-Ching Wu, Tsung-Wen Chen, Yi-Yin Jan, Miin-Fu Chen
Pages: 49-56
Published online on: 01 January 2009

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Article

Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/β-catenin complex

Ha Na Choi, Kyung Ryoul Kim, Ji Hyun Lee, Ho Sung Park, Kyu Yun Jang, Myoung Ja Chung, Si Eun Hwang, Hee Chul Yu, Woo Sung Moon
Pages: 57-63
Published online on: 01 January 2009

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Article

Expression of CXCL12 and its receptor CXCR4 in esophageal squamous cell carcinoma

Ken Sasaki, Shoji Natsugoe, Sumiya Ishigami, Masataka Matsumoto, Hiroshi Okumura, Tetsuro Setoyama, Yasuto Uchikado, Yoshiaki Kita, Kiyokazu Tamotsu, Koichi Hanazono, Tetsuhiro Owaki, Takashi Aikou
Pages: 65-71
Published online on: 01 January 2009

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Protein profiling of post-prostatic massage urine specimens by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry to discriminate between prostate cancer and benign lesions

Akiko Okamoto, Hayato Yamamoto, Atsushi Imai, Shingo Hatakeyama, Ikuya Iwabuchi, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Noritaka Kamimura, Kazuyuki Mori, Kanemitsu Yamaya, Chikara Ohyama
Pages: 73-79
Published online on: 01 January 2009

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Article

Association between expression of human papillomavirus 16/18 E6 oncoprotein and survival in patients with stage I non-small cell lung cancer

Nan-Yung Hsu, Ya-Wen Cheng, I-Ping Chan, Heng-Chien Ho, Chih-Yi Chen, Chung-Ping Hsu, Meng-Hung Lin, Ming-Chih Chou
Pages: 81-87
Published online on: 01 January 2009

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Article

A new therapeutic modality involving acridine orange excitation by photon energy used during reduction surgery for rhabdomyosarcomas

Takao Matsubara, Katsuyuki Kusuzaki, Akihiko Matsumine, Hiroaki Murata, Haruhiko Satonaka, Ken Shintani, Tomoki Nakamura, Hajime Hosoi, Tomoko Iehara, Toru Sugimoto, Atsumasa Uchida
Pages: 89-94
Published online on: 01 January 2009

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Article

Immunohistochemical analysis of Reg IV in urogenital organs: Frequent expression of Reg IV in prostate cancer and potential utility as serum tumor marker

Tetsutaro Hayashi, Akio Matsubara, Shinya Ohara, Koji Mita, Yasuhisa Hasegawa, Tsuguru Usui, Koji Arihiro, Shinichi Norimura, Kazuhiro Sentani, Naohide Oue, Wataru Yasui
Pages: 95-100
Published online on: 01 January 2009

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Article

Clinical significance of chicken ovalbumin upstream promoter-transcription factor II expression in human colorectal cancer

Sung-Won Shin, Hyuk-Chan Kwon, Mee-Sook Rho, Hong-Jo Choi, Jong-Young Kwak, Joo-In Park
Pages: 101-106
Published online on: 01 January 2009

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Article Open Access

Gastric-and-intestinal mixed endocrine cell phenotypic expression of carcinoid tumors in the rectum

Yoshikazu Hirata, Tsutomu Mizoshita, Takashi Mizushima, Takaya Shimura, Yoshinori Mori, Eiji Kubota, Tsuneya Wada, Naotaka Ogasawara, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki, Takeshi Kamiya, Tetsuya Tsukamoto, Masae Tatematsu, Takashi Joh
Pages: 107-112
Published online on: 01 January 2009

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Article

Claudin expression in rectal well-differentiated endocrine neoplasms (carcinoid tumors)

Mitsuaki Ishida, Ryoji Kushima, Hidetoshi Okabe
Pages: 113-117
Published online on: 01 January 2009

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Article

Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear localization of nestin

Tomas Loja, Petr Chlapek, Petr Kuglik, Martina Pesakova, Alexandra Oltova, Pavel Cejpek, Renata Veselska
Pages: 119-127
Published online on: 01 January 2009

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Article

Focal adhesion kinase: Important to prostaglandin E2-mediated adhesion, migration and invasion in hepatocellular carcinoma cells

Xiao-Ming Bai, Wei Zhang, Ning-Bo Liu, Hui Jiang, Ke-Xin Lou, Tao Peng, Juan Ma, Li Zhang, Hai Zhang, Jing Leng
Pages: 129-136
Published online on: 01 January 2009

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Article

Relationship of activated extracellular signal-regulated kinase 1/2 with lung metastasis in salivary adenoid cystic carcinoma

Kai Hu, Ye-Hua Gan, Sheng-Lin Li, Yan Gao, Deng-Cheng Wu, Cun-Yu Wang, Guang-Yan Yu
Pages: 137-143
Published online on: 01 January 2009

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Article

A low molecular weight polysaccharide isolated from Agaricus blazei suppresses tumor growth and angiogenesis in vivo

Y. C. Niu, J. C. Liu, X. M. Zhao, X. X. Wu
Pages: 145-152
Published online on: 01 January 2009

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Article

Decreased expression of the chemokine CCL21 in human colorectal adenocarcinomas

Melad Mumtaz, Dick Wågsäter, Sture Löfgren, Anders Hugander, Niklas Zar, Jan Dimberg
Pages: 153-158
Published online on: 01 January 2009

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Article

Decreased expression of KAI1/CD82 metastasis suppressor gene is associated with loss of heterozygosity in melanoma cell lines

Young Il Kim, Min-Kyung Shin, Jin-Woo Lee, Joo-Ho Chung, Mu-Hyoung Lee
Pages: 159-164
Published online on: 01 January 2009

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Article

Retargeting improves the efficacy of a telomerase-dependent oncolytic adenovirus for head and neck cancer

Raine Toivonen, Elina Suominen, Reidar Grenman, Mikko Savontaus
Pages: 165-171
Published online on: 01 January 2009

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Article Open Access

Impaired ζ chain expression and IFN-γ production in peripheral blood T and NK cells of patients with advanced lung cancer

Lidia Ciszak, Agata Kosmaczewska, Bozena Werynska, Aleksandra Szteblich, Renata Jankowska, Irena Frydecka
Pages: 173-184
Published online on: 01 January 2009

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Article

Isothiocyanates repress estrogen receptor α expression in breast cancer cells

Lianguo Kang, Ling Ding, Zhao-Yi Wang
Pages: 185-192
Published online on: 01 January 2009

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Article

Medium adsorbance fraction of reticulocyte and myeloperoxidase index may individuate a patient subset with a low risk of chemotherapy-related neutropenia

Giulio Giordano, Pier Francesco Ferrucci, Chiara Nicci, Tiziana Grafone, Rosa Tambaro, Stefano Papini, Giuliana Farina, Silvia Piano, Bruno Zappacosta, Sergio Storti
Pages: 193-198
Published online on: 01 January 2009

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Article

Mitochondrial ultrastructure-associated chemotherapy response in ovarian cancer

Motoaki Saitou, Seiji Isonishi, Tomomi Hamada, Takako Kiyokawa, Toshiaki Tachibana, Hiroshi Ishikawa, Makoto Yasuda
Pages: 199-204
Published online on: 01 January 2009

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Article

Inhibition of TGF-β1 suppresses motility and invasiveness of oral squamous cell carcinoma cell lines via modulation of integrins and down-regulation of matrix-metalloproteinases

Sayaka Takayama, Masashi Hatori, Yuji Kurihara, Yuriko Kinugasa, Tatsuo Shirota, Satoru Shintani
Pages: 205-210
Published online on: 01 January 2009

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Article

Overexpression of the fibroblast growth factor receptor-1 gene correlates with liver metastasis in colorectal cancer

Tsutomu Sato, Takashi Oshima, Kazue Yoshihara, Naoto Yamamoto, Roppei Yamada, Yasuhiko Nagano, Shoichi Fujii, Chikara Kunisaki, Manabu Shiozawa, Makoto Akaike, Yasushi Rino, Katsuaki Tanaka, Munetaka Masuda, Toshio Imada
Pages: 211-216
Published online on: 01 January 2009

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Article

Progression of breast tumors is accompanied by a decrease in expression of the Rho guanine exchange factor Tiam1

A. Stebel, C. Brachetti, M. Kunkel, M. Schmidt, G. Fritz
Pages: 217-222
Published online on: 01 January 2009

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Article

Long-term trends of the incidence of hepatocellular carcinoma in the Nagasaki prefecture, Japan

Naota Taura, Hiroshi Yatsuhashi, Kazuhiko Nakao, Tatsuki Ichikawa, Hiromi Ishibashi
Pages: 223-227
Published online on: 01 January 2009

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Article

The expression of CRM1 is associated with prognosis in human osteosarcoma

Yang Yao, Yang Dong, Feng Lin, Hui Zhao, Zan Shen, Ping Chen, Yuan-Jue Sun, Li-Na Tang, Shui-Er Zheng
Pages: 229-235
Published online on: 01 January 2009

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Article

Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo

Harun M. Said, Susanne Stein, Carsten Hagemann, Buelent Polat, Adrian Staab, Jelena Anacker, Beate Schoemig, Matthias Theobald, Michael Flentje, Dirk Vordermark
Pages: 237-246
Published online on: 01 January 2009

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Article

DNA cytometry and kinetics of rat urothelial lesions during chemical carcinogenesis

C. Palmeira, P. A. Oliveira, R. Arantes-Rodrigues, A. Colaço, P. L.F. De la Cruz, C. Lopes, L. Santos
Pages: 247-252
Published online on: 01 January 2009

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Article

Tiron, a ROS scavenger, protects human lung cancer Calu-6 cells against antimycin A-induced cell death

Yong Hwan Han, Woo Hyun Park
Pages: 253-261
Published online on: 01 January 2009

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Article

ABCC10/MRP7 is associated with vinorelbine resistance in non-small cell lung cancer

Yuji Bessho, Tetsuya Oguri, Hiroaki Ozasa, Takehiro Uemura, Hideo Sakamoto, Mikinori Miyazaki, Ken Maeno, Shigeki Sato, Ryuzo Ueda
Pages: 263-268
Published online on: 01 January 2009

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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