Journal Articles

Article Open Access

Quantification of internalization of EGFR-binding Affibody molecules: Methodological aspects

Lovisa Göstring, Ming Tsuey Chew, Anna Orlova, Ingmarie Höidén-Guthenberg, Anders Wennborg, Jörgen Carlsson, Fredrik Y. Frejd

Pages: 757-763 Published online on: 01 April 2010
Article

MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues

Keisuke Okudaira, Sanjay Kakar, Lisa Cun, Ester Choi, Rina Wu DeCamillis, Soichiro Miura, Marvin H. Sleisenger, Young S. Kim, Gouren Deng

Pages: 765-775 Published online on: 01 April 2010
Article

Targeted photodynamic therapy for prostate cancer: Inducing apoptosis via activation of the caspase-8/-3 cascade pathway

Tiancheng Liu, Lisa Y. Wu, Joseph K. Choi, Clifford E. Berkman

Pages: 777-784 Published online on: 01 April 2010
Article

HIF1-positive and HIF1-negative glioblastoma cells compete in vitro but cooperate in tumor growth in vivo

Paolo Fiorenzo, Maria Patrizia Mongiardi, Diletta Dimitri, Mauro Cozzolino, Alberto Ferri, Nicola Montano, Gianluca Trevisi, Giulio Maira, Luca Battistini, Maria Laura Falchetti, Andrea Levi, Roberto Pallini

Pages: 785-791 Published online on: 01 April 2010
Article

Tumor-derived trypsin enhances proliferation of intrahepatic cholangiocarcinoma cells by activating protease-activated receptor-2

Shin-Ichi Nakanuma, Hidehiro Tajima, Kouichi Okamoto, Hironori Hayashi, Hisatoshi Nakagawara, Ichiro Onishi, Hiroyuki Takamura, Hirohisa Kitagawa, Sachio Fushida, Takashi Tani, Takashi Fujimura, Masato Kayahara, Tetsuo Ohta, Tomohiko Wakayama, Shoichi Iseki, Shin-Ichi Harada

Pages: 793-800 Published online on: 01 April 2010
Article

Radiation-inducible silencing of uPA and uPAR in vitro and in vivo in meningioma

Venkateswara Rao Gogineni, Arun Kumar Nalla, Reshu Gupta, Bharathi Gorantla, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao

Pages: 809-816 Published online on: 01 April 2010
Article

Upregulation of Notch pathway molecules in oral squamous cell carcinoma

Hiroshi Hijioka, Takao Setoguchi, Akihiko Miyawaki, Hui Gao, Takayuki Ishida, Setsuro Komiya, Norifumi Nakamura

Pages: 817-822 Published online on: 01 April 2010
Article

Downregulation of SS18-SSX1 expression in synovial sarcoma by small interfering RNA enhances the focal adhesion pathway and inhibits anchorage-independent growth in vitro and tumor growth in vivo

Satoshi Takenaka, Norifumi Naka, Nobuhito Araki, Nobuyuki Hashimoto, Takafumi Ueda, Kiyoko Yoshioka, Hideki Yoshikawa, Kazuyuki Itoh

Pages: 823-831 Published online on: 01 April 2010
Article

Neoplastic progression of the human breast cancer cell line G3S1 is associated with elevation of cytoskeletal dynamics and upregulation of MT1-MMP

Ondrej Tolde, Daniel Rösel, Claudia T. Mierke, Daniela Panková, Petr Folk, Pavel Vesely, Jan Brábek

Pages: 833-839 Published online on: 01 April 2010
Article

Regulatory T cell depletion enhances tumor specific CD8 T-cell responses, elicited by tumor antigen NY-ESO-1b in hepatocellular carcinoma patients, in vitro

Heng-Hui Zhang, Ming-Hui Mei, Ran Fei, Wei-Jia Liao, Xue-Yan Wang, Li-Ling Qin, Jiang-Hua Wang, Lai Wei, Hong-Song Chen

Pages: 841-848 Published online on: 01 April 2010
Article

Development of an oral cancer recurrence mouse model after surgical resection

Andreas Behren, York Kamenisch, Sabrina Muehlen, Christa Flechtenmacher, Uwe Haberkorn, Hermann Hilber, Jeffrey N. Myers, Zazie Bergmann, Peter Karl Plinkert, Christian Simon

Pages: 849-855 Published online on: 01 April 2010
Article

Carvedilol in glioma treatment alone and with imatinib in vitro

Mine Erguven, Nuray Yazihan, Esin Aktas, Akin Sabanci, Chiang J. Li, Gulperi Oktem, Ayhan Bilir

Pages: 857-866 Published online on: 01 April 2010
Article

The antitumor effect of PLK1 and HSF1 double knockdown on human oral carcinoma cells

Soo-A Kim, Seong-Min Kwon, Jung-Hoon Yoon, Sang-Gun Ahn

Pages: 867-872 Published online on: 01 April 2010
Article

Targeting the cell cycle and the PI3K pathway: A possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells

Thérèse David-Pfeuty, Michel Legraverend, Odile Ludwig, David S. Grierson

Pages: 873-881 Published online on: 01 April 2010
Article

PKCε induces Bcl-2 by activating CREB

Eswar Shankar, Soumya Krishnamurthy, Rajiv Paranandi, Alakananda Basu

Pages: 883-888 Published online on: 01 April 2010
Article

Immunohistochemical profiling of node negative breast carcinomas allows prediction of metastatic risk

Sophie Giusiano, Veronique Secq, Xavier Carcopino, Severine Carpentier, Lucile Andrac, Marie-Noelle Lavaut, Claude Allasia, Pascal Bonnier, Juan Lucio Iovanna, Stephane Garcia, Leon Boubli, Daniel Birnbaum, Colette Charpin

Pages: 889-898 Published online on: 01 April 2010
Article

Overexpression of Apg-2 increases cell proliferation and protects from oxidative damage in BaF3-BCR/ABL cells

Chunli Li, Dingbin Liu, Ying Yuan, Shifeng Huang, Meng Shi, Kun Tao, Wenli Feng

Pages: 899-904 Published online on: 01 April 2010
Article

A new system for regulated functional gene expression for gene therapy applications: Nuclear delivery of a p16INK4A-estrogen receptor carboxy terminal fusion protein only in the presence of estrogen

Tomohiro Tamura, Tatsuya Kanuma, Tomoko Nakazato, Leri S. Faried, Hiroshi Aoki, Takashi Minegishi

Pages: 905-912 Published online on: 01 April 2010
Article

miR-221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang

Pages: 913-920 Published online on: 01 April 2010
Article

17β-estradiol induces up-regulation of PTEN and PPARγ in leiomyoma cells, but not in normal cells

Young-Ju Jeong, Eun-Mi Noh, Young-Rae Lee, Hong-Nu Yu, Kyu-Yun Jang, Seung Jin Lee, Jonghyeon Kim, Jong-Suk Kim

Pages: 921-927 Published online on: 01 April 2010
Article

Global screening and extended nomenclature for 230 aphidicolin-inducible fragile sites, including 61 yet unreported ones

Kristin Mrasek, Christiane Schoder, Anne-Christin Teichmann, Katja Behr, Britta Franze, Kathleen Wilhelm, Nancy Blaurock, Uwe Claussen, Thomas Liehr, Anja Weise

Pages: 929-940 Published online on: 01 April 2010
Article

Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IκB/NF-κB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway

Hwa Young Lee, Suzanne Crawley, Ryota Hokari, Sungwon Kwon, Young S. Kim

Pages: 941-953 Published online on: 01 April 2010
Article

SIRT3 SNPs validation in 640 individuals, functional analyses and new insights into SIRT3 stability

Christian-Lars Dransfeld, Hamed Alborzinia, Stefan Wölfl, Ulrich Mahlknecht

Pages: 955-960 Published online on: 01 April 2010
Article

Isostrychnopentamine, an indolomonoterpenic alkaloid from Strychnos usambarensis, with potential anti-tumor activity against apoptosis-resistant cancer cells Corrigendum in /ijo/36/5/1315

El-Hadj Saidou Balde, Véronique Mégalizzi, Martine Cao, Luc Angenot, Robert Kiss, Marc Van Damme, Michel Frederich

Pages: 961-965 Published online on: 01 April 2010
Article

Effects of an EGFR-binding affibody molecule on intracellular signaling pathways

E. Nordberg, L. Ekerljung, S. H. Sahlberg, J. Carlsson, J. Lennartsson, B. Glimelius

Pages: 967-972 Published online on: 01 April 2010
Article

Mass spectrometric detection of candidate protein biomarkers of cancer cachexia in human urine

Richard J.E. Skipworth, Grant D. Stewart, Mishaim Bhana, Jennifer Christie, Catharine M. Sturgeon, Denis C. Guttridge, Andrew D. Cronshaw, Kenneth C.H. Fearon, James A. Ross

Pages: 973-982 Published online on: 01 April 2010
Article

Heterozygous TP53stop146/R72P fibroblasts from a Li-Fraumeni syndrome patient with impaired response to DNA damage

Juliana De Moura, Flávia Ludimila Kavalec, Mabrouka Doghman, Roberto Rosati, Gislaine Custodio, Enzo Lalli, Glaci Moura D. Cavallari, Jesus Santa Maria, Bonald C. Figueiredo

Pages: 983-990 Published online on: 01 April 2010
Article

The cell cycle effects of docosahexaenoic acid on human metastatic hepatocellular carcinoma proliferation

Carol Yee-Ki Lee, Wai-Hung Sit, Sheung-Tat Fan, Kwan Man, Irene Wing-Yan Jor, Leo Lap-Yan Wong, Murphy Lam-Yim Wan, Kian Cheng Tan-Un, Jennifer Man-Fan Wan

Pages: 991-998 Published online on: 01 April 2010
Article

Differential effects of resveratrol and novel resveratrol derivative, HS-1793, on endoplasmic reticulum stress-mediated apoptosis and Akt inactivation

Hee Jung Um, Jae Hoon Bae, Jong-Wook Park, Hongsuk Suh, Na Young Jeong, Young Hyun Yoo, Taeg Kyu Kwon

Pages: 1007-1013 Published online on: 01 April 2010
Article

Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma

Babett Bartling, Grit Rehbein, Andreas Simm, Rolf-Edgar Silber, Hans-Stefan Hofmann

Pages: 1015-1021 Published online on: 01 April 2010
Article

Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation

Il-Rae Cho, Sang Seok Koh, Hye-Jin Min, Eun-Hee Park, Ratakorn Srisuttee, Byung Hak Jhun, Chi Duk Kang, Manbok Kim, Randal N. Johnston, Young-Hwa Chung

Pages: 1023-1030 Published online on: 01 April 2010
Article

Identification of a functional p53 responsive element within the promoter of XAF1 gene in gastrointestinal cancer cells

Wenjing Zhang, Zheng Guo, Bo Jiang, Lingyun Niu, Guosheng Xia, Xinying Wang, Tianming Cheng, Yusheng Zhang, Jide Wang

Pages: 1031-1037 Published online on: 01 April 2010
Article

Increase of the therapeutic effect by treating nasopharyngeal tumor with combination of HER-2 siRNA and paclitaxel

Yoshiyuki Hattori, Motoki Hakoshima, Kimiko Koga, Yoshie Maitani

Pages: 1039-1046 Published online on: 01 April 2010
Journal Cover

Cover Legend PDF

April 2010
Volume 36 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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