Journal Articles

Review

The characteristic ultrasound features of specific types of ovarian pathology (Review)

Ahmad Sayasneh, Christine Ekechi, Laura Ferrara, Jeroen Kaijser, Catriona Stalder, Shyamaly Sur, Dirk Timmerman, Tom Bourne

Pages: 445-458 Published online on: 18 November 2014
Review

BTG2: A rising star of tumor suppressors (Review)

Bijing Mao, Zhimin Zhang, Ge Wang

Pages: 459-464 Published online on: 18 November 2014
Review

Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)

Nidhi Jariwala, Devaraja Rajasekaran, Jyoti Srivastava, Rachel Gredler, Maaged A. Akiel, Chadia L. Robertson, Luni Emdad, Paul B. Fisher, Devanand Sarkar

Pages: 465-473 Published online on: 18 November 2014
Article Open Access

Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells

Shota Moriya, Seiichiro Komatsu, Kaho Yamasaki, Yusuke Kawai, Hiroko Kokuba, Ayako Hirota, Xiao‑Fang Che, Masato Inazu, Akihiko Gotoh, Masaki Hiramoto, Keisuke Miyazawa

Pages: 474-486 Published online on: 24 November 2014
Article Open Access

Dual regulation of receptor tyrosine kinase genes EGFR and c-Met by the tumor-suppressive microRNA-23b/27b cluster in bladder cancer

Takeshi Chiyomaru, Naohiko Seki, Satoru Inoguchi, Tomoaki Ishihara, Hiroko Mataki, Ryosuke Matsushita, Yusuke Goto, Rika Nishikawa, Shuichi Tatarano, Toshihiko Itesako, Masayuki Nakagawa, Hideki Enokida

Pages: 487-496 Published online on: 14 November 2014
Article Open Access

A peptide antigen derived from EGFR T790M is immunogenic in non‑small cell lung cancer

Kazuya Ofuji, Yoshitaka Tada, Toshiaki Yoshikawa, Manami Shimomura, Mayuko Yoshimura, Keigo Saito, Yasunari Nakamoto, Tetsuya Nakatsura

Pages: 497-504 Published online on: 01 December 2014
Article Open Access

Prognostic significance of PIK3CA and SOX2 in Asian patients with lung squamous cell carcinoma

Yoshihito Iijima, Masahiro Seike, Rintaro Noro, Takayuki Ibi, Shingo Takeuchi, Iwao Mikami, Kiyoshi Koizumi, Jitsuo Usuda, Akihiko Gemma

Pages: 505-512 Published online on: 10 November 2014
Article Open Access

Imaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 Affibody molecule

Hadis Honarvar, Javad Garousi, Elin Gunneriusson, Ingmarie Höidén-Guthenberg, Mohamed Altai, Charles Widström, Vladimir Tolmachev, Fredrik Y. Frejd

Pages: 513-520 Published online on: 27 November 2014
Article Open Access

Long non-coding RNA HOTAIR is associated with human cervical cancer progression

Hee Jung Kim, Dae Woo Lee, Ga Won Yim, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim

Pages: 521-530 Published online on: 17 November 2014
Article Open Access

miR-429 inhibits migration and invasion of breast cancer cells in vitro

Zhi-Bin Ye, Gang Ma, Ya-Hui Zhao, Yun Xiao, Yun Zhan, Chao Jing, Kai Gao, Zhi-Hua Liu, Sheng-Ji Yu

Pages: 531-538 Published online on: 17 November 2014
Article Open Access

Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer

Makoto Abue, Misa Yokoyama, Rie Shibuya, Keiichi Tamai, Kazunori Yamaguchi, Ikuro Sato, Nobuyuki Tanaka, Shin Hamada, Tooru Shimosegawa, Kazuo Sugamura, Kennichi Satoh

Pages: 539-547 Published online on: 10 November 2014
Article

Prostaglandin I2 analog suppresses lung metastasis by recruiting pericytes in tumor angiogenesis

Yoshinori Minami, Takaaki Sasaki, Hiroki Bochimoto, Jun‑Ichi Kawabe, Satoshi Endo, Yoshiki Hira, Tsuyoshi Watanabe, Shunsuke Okumura, Naoyuki Hasebe, Yoshinobu Ohsaki

Pages: 548-554 Published online on: 28 November 2014
Article

Wedelolactone inhibits breast cancer-induced osteoclastogenesis by decreasing Akt/mTOR signaling

Chia-Jung Hsieh, Po-Lin Kuo, Ming-Feng Hou, Jen-Yu Hung, Fang-Rong Chang, Ying-Chan Hsu, Ya-Fang Huang, Eing-Mei Tsai, Ya-Ling Hsu

Pages: 555-562 Published online on: 21 November 2014
Article

The value of trefoil factor 3 expression in predicting the long‑term outcome and early recurrence of colorectal cancer

Kiyoto Morito, Jun Nakamura, Yoshihiko Kitajima, Keita Kai, Tomokazu Tanaka, Hiroshi Kubo, Shuusuke Miyake, Hirokazu Noshiro

Pages: 563-568 Published online on: 17 November 2014
Article

Comprehensive evaluation of the response of genes to the administration of the antitumor drug S-1 using a low density array

Hisashi Matsuoka, Kazuya Kondo, Hiromitsu Takizawa, Haruhiko Fujino, Etsuko Sakamoto, Junji Uchida, Koh Uyama, Hiroaki Toba, Koichiro Kenzaki, Shoji Sakiyama, Akira Tangoku

Pages: 569-577 Published online on: 17 November 2014
Article Open Access

6,7-di-O-acetylsinococuline (FK-3000) induces G2/M phase arrest in breast carcinomas through p38 MAPK phosphorylation and CDC25B dephosphorylation

Yong-Chun Li, Bong-Hee Kim, Soon-Chang Cho, Mi-Ae Bang, Sunmin Kim, Dae-Hun Park

Pages: 578-586 Published online on: 07 November 2014
Article

Macrophage-secreted IL-8 induces epithelial-mesenchymal transition in hepatocellular carcinoma cells by activating the JAK2/STAT3/Snail pathway

Xiu-Tao Fu, Zhi Dai, Kang Song, Zhuo-Jun Zhang, Zheng-Jun Zhou, Shao-Lai Zhou, Yi-Ming Zhao, Yong-Sheng Xiao, Qi-Man Sun, Zhen-Bin Ding, Jia Fan

Pages: 587-596 Published online on: 18 November 2014
Article

Protumorigenic role of Timeless in hepatocellular carcinoma

Nahla Elgohary, Rossella Pellegrino, Olaf Neumann, Heba M. Elzawahry, Magdy M. Saber, Ahmed A. Zeeneldin, Robert Geffers, Volker Ehemann, Peter Schemmer, Peter Schirmacher, Thomas Longerich

Pages: 597-606 Published online on: 14 November 2014
Article

TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based standard chemotherapy in patients diagnosed with advanced serous ovarian carcinoma

Pavla Brachova, Samuel R. Mueting, Matthew J. Carlson, Michael J. Goodheart, Anna M. Button, Sarah L. Mott, Donghai Dai, Kristina W. Thiel, Eric J. Devor, Kimberly K. Leslie

Pages: 607-618 Published online on: 11 November 2014
Article

Expression and anticancer activity analysis of recombinant human uPA1‑43-melittin

Manman Su, Weiqin Chang, Manhua Cui, Yang Lin, Shuying Wu, Tianmin Xu

Pages: 619-626 Published online on: 13 November 2014
Article

Norcantharidin enhances TIMP‑2 anti‑vasculogenic mimicry activity for human gallbladder cancers through downregulating MMP‑2 and MT1‑MMP

Wei Zhu, Wei Sun, Jing‑Tao Zhang, Zhong‑Yan Liu, Xin‑Ping Li, Yue‑Zu Fan

Pages: 627-640 Published online on: 14 November 2014
Article

B‑cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular carcinoma

Mitsuro Kanda, Hiroyuki Sugimoto, Shuji Nomoto, Hisaharu Oya, Soki Hibino, Dai Shimizu, Hideki Takami, Ryoji Hashimoto, Yukiyasu Okamura, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera

Pages: 641-648 Published online on: 18 November 2014
Article

SPAG6 silencing inhibits the growth of the malignant myeloid cell lines SKM-1 and K562 via activating p53 and caspase activation-dependent apoptosis

Bihui Yang, Li Wang, Xiaohua Luo, Liping Chen, Zesong Yang, Lin Liu

Pages: 649-656 Published online on: 18 November 2014
Article

Cell polarity protein CRB3 is an independent favorable prognostic factor for clear cell renal cell carcinoma

Xiaona Mao, Pingping Li, Yu Ren, Juan Li, Can Zhou, Jin Yang, Peijun Liu

Pages: 657-666 Published online on: 18 November 2014
Article

The HMGB1 protein sensitizes colon carcinoma cells to cell death triggered by pro-apoptotic agents

Chengcheng Christine Zhang, Georg Gdynia, Volker Ehemann, Wilfried Roth

Pages: 667-676 Published online on: 01 December 2014
Article

Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins

Xiaochen Li, Xiansheng Liu, Yongjian Xu, Yuanzhou He, Jin Liu, Min Xie

Pages: 677-684 Published online on: 26 November 2014
Article

Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-β1/ZEB/miR‑200 signaling network

Aling Shen, Wei Lin, Youqin Chen, Liya Liu, Hongwei Chen, Qunchuan Zhuang, Jiumao Lin, Thomas J. Sferra, Jun Peng

Pages: 685-690 Published online on: 24 November 2014
Article

Mitochondrial dynamics regulates hypoxia-induced migration and antineoplastic activity of cisplatin in breast cancer cells

Xiao-Jian Han, Zhang-Jian Yang, Li-Ping Jiang, Yong-Fang Wei, Ming-Fang Liao, Yisong Qian, Yong Li, Xuan Huang, Jian-Bin Wang, Hong-Bo Xin, Yu-Ying Wan

Pages: 691-700 Published online on: 27 November 2014
Article

Different subcellular localizations and functions of human ARD1 variants

Ji Hae Seo, Ji-Hyeon Park, Eun Ji Lee, Kyu-Won Kim

Pages: 701-707 Published online on: 21 November 2014
Article

Oligomer procyanidins (F2) isolated from grape seeds inhibits tumor angiogenesis and cell invasion by targeting HIF-1α in vitro

Hong Li Zheng, Jingyu Yang, Yue Hou, Baoshan Sun, Qingchun Zhang, Yanhua Mou, Lihui Wand, Chunfu Wu

Pages: 708-720 Published online on: 10 November 2014
Article

Imidazole inhibits autophagy flux by blocking autophagic degradation and triggers apoptosis via increasing FoxO3a-Bim expression

Zhenxing Liu, Yingzheng Wang, Shuan Zhao, Jingyou Zhang, Yi Wu, Shenming Zeng

Pages: 721-731 Published online on: 21 November 2014
Article

Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1

Chao Gao, Chun Han, Qiyao Yu, Yue Guan, Na Li, Jingjing Zhou, Yanming Tian, Yi Zhang

Pages: 732-740 Published online on: 13 November 2014
Article

Combination effect of photodynamic therapy using NPe6 with pemetrexed for human malignant pleural mesothelioma cells

Sachio Maehara, Jitsuo Usuda, Taichiro Ishizumi, Shuji Ichinose, Keishi Ohtani, Tatsuya Inoue, Kentaro Imai, Hideyuki Furumoto, Yujin Kudo, Naohiro Kajiwara, Tatsuya Ohira, Norihiko Ikeda

Pages: 741-749 Published online on: 10 November 2014
Article

Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells

Yong Sun, Xing Xing, Qi Liu, Zheng Wang, Yuhu Xin, Ping Zhang, Chaosu Hu, Yong Liu

Pages: 750-756 Published online on: 10 November 2014
Article

Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li

Pages: 757-763 Published online on: 13 November 2014
Article

Paeonol suppresses lipid accumulation in macrophages via upregulation of the ATP‑binding cassette transporter A1 and downregulation of the cluster of differentiation 36

Xiuying Li, Yuanda Zhou, Chao Yu, Hui Yang, Chengzhi Zhang, Yun Ye, Shunlin Xiao

Pages: 764-774 Published online on: 17 November 2014
Article

Ginsenoside 20(S)‑Rg3 inhibits the Warburg effect through STAT3 pathways in ovarian cancer cells

Jie Li, Ting Liu, Le Zhao, Wei Chen, Huilian Hou, Zhongxue Ye, Xu Li

Pages: 775-781 Published online on: 18 November 2014
Article

Mechanistic and biological significance of DNA methyltransferase 1 upregulated by growth factors in human hepatocellular carcinoma

Qin-Liang Fang, Yi-Rui Yin, Cheng-Rong Xie, Sheng Zhang, Wen-Xiu Zhao, Chao Pan, Xiao-Min Wang, Zhen-Yu Yin

Pages: 782-790 Published online on: 24 November 2014
Article

Gene expression profile for predicting survival of patients with meningioma

Feng Chen, Chun-Xiang Xiang, Yi Zhou, Xiang-Sheng Ao, Da-Quan Zhou, Peng Peng, Hai-Quan Zhang, Han-Dong Liu, Xing Huang

Pages: 791-797 Published online on: 25 November 2014
Article

The tumor suppressor miR-124 inhibits cell proliferation by targeting STAT3 and functions as a prognostic marker for postoperative NSCLC patients

Xiumei Li, Zhuang Yu, Yong Li, Shihai Liu, Caihong Gao, Xin Hou, Ruyong Yao, Lianhua Cui

Pages: 798-808 Published online on: 01 December 2014
Article

Excision repair cross complementation group 1 is a chemotherapy-tolerating gene in cisplatin-based treatment for non-small cell lung cancer

Shoufeng Wang, Hong Pan, Desen Liu, Naiquan Mao, Chuantian Zuo, Li Li, Tong Xie, Dingming Huang, Yaoyuan Huang, Qi Pan, Li Yang, Junwei Wu

Pages: 809-817 Published online on: 28 November 2014
Article

p53 suppresses 14-3-3γ by stimulating proteasome-mediated 14-3-3γ protein degradation

De-Yu Chen, Dong-Fang Dai, Ye Hua, Wen-Qing Qi

Pages: 818-824 Published online on: 07 November 2014
Article

A novel bicompartmental mathematical model of glioblastoma multiforme

Leith Hathout, Benjamin M. Ellingson, Timothy Cloughesy, Whitney B. Pope

Pages: 825-832 Published online on: 10 November 2014
Article

Voltage‑gated K+ channel blocker quinidine inhibits proliferation and induces apoptosis by regulating expression of microRNAs in human glioma U87‑MG cells

Qin Ru, Xiang Tian, Ming‑Shan Pi, Lin Chen, Kai Yue, Qi Xiong, Bao‑Miao Ma, Chao‑Ying Li

Pages: 833-840 Published online on: 25 November 2014
Article

Cotylenin A and arsenic trioxide cooperatively suppress cell proliferation and cell invasion activity in human breast cancer cells

Takashi Kasukabe, Junko Okabe-Kado, Nobuo Kato, Yoshio Honma, Shunichi Kumakura

Pages: 841-848 Published online on: 18 November 2014
Article

miR-224 overexpression is a strong and independent prognosticator of short-term relapse and poor overall survival in colorectal adenocarcinoma

Panagiotis G. Adamopoulos, Christos K. Kontos, Stamatia-Maria Rapti, Iordanis N. Papadopoulos, Andreas Scorilas

Pages: 849-859 Published online on: 24 November 2014
Article

Multiple myeloma proteostasis can be targeted via translation initiation factor eIF4E

Victoria Zismanov, Oshrat Attar‑Schneider, Michael Lishner, Rachel Heffez Aizenfeld, Shelly Tartakover Matalon, Liat Drucker

Pages: 860-870 Published online on: 24 November 2014
Article

Label-free and amplification-free miR-124 detection in human cells

Kristyna Smerkova, Kristyna Hudcova, Veronika Vlahova, Marketa Vaculovicova, Vladimir Pekarik, Michal Masarik, Vojtech Adam, Rene Kizek

Pages: 871-877 Published online on: 17 November 2014
Article

Estrogen receptor β selective agonists reduce invasiveness of triple‑negative breast cancer cells

Oliver Hinsche, Rainer Girgert, Günter Emons, Carsten Gründker

Pages: 878-884 Published online on: 25 November 2014
Journal Cover

Cover Legend PDF

February-2015
Volume 46 Issue 2

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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