Journal Articles

Article Open Access

Honokiol suppresses metastasis of renal cell carcinoma by targeting KISS1/KISS1R signaling

Shujie Cheng, Victor Castillo, Isaac Eliaz, Daniel Sliva

Pages: 2293-2298 Published online on: 02 April 2015
Article Open Access

The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment

Laura Annovazzi, Valentina Caldera, Marta Mellai, Chiara Riganti, Luigi Battaglia, Daniela Chirio, Antonio Melcarne, Davide Schiffer

Pages: 2299-2308 Published online on: 16 April 2015
Article Open Access

FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression

Hong De Xu, Soon-Chang Cho, Mi-Ae Bang, Chun-Sik Bae, Yeonshik Choi, Yong-Chun Li, Seung-Kil Lim, Jaegal Shim, Dae-Hun Park

Pages: 2309-2316 Published online on: 27 March 2015
Article Open Access

Taurolithocholic acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway

Sumet Amonyingcharoen, Tawit Suriyo, Apinya Thiantanawat, Piyajit Watcharasit, Jutamaad Satayavivad

Pages: 2317-2326 Published online on: 27 March 2015
Article Open Access

Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA

Kazuki Sakamoto, Tatsushi Yokogawa, Hiroyuki Ueno, Kei Oguchi, Hiromi Kazuno, Keiji Ishida, Nozomu Tanaka, Akiko Osada, Yukari Yamada, Hiroyuki Okabe, Kenichi Matsuo

Pages: 2327-2334 Published online on: 20 April 2015
Article Open Access

The novel desmopressin analogue [V4Q5]dDAVP inhibits angiogenesis, tumour growth and metastases in vasopressin type 2 receptor-expressing breast cancer models

Juan Garona, Marina Pifano, Ulises D. Orlando, Maria B. Pastrian, Nancy B. Iannucci, Hugo H. Ortega, Ernesto J. Podesta, Daniel E. Gomez, Giselle V. Ripoll, Daniel F. Alonso

Pages: 2335-2345 Published online on: 03 April 2015
Article Open Access

Effect of HIF-1α on biological activation of human tongue squamous cell carcinoma SCC-15 cells in vitro

Xiaokang Zhou, Danqing Huang, Zhongxiu Xue, Xiuhui Xu, Kai Wang, Yao Sun, Feiwu Kang

Pages: 2346-2354 Published online on: 26 March 2015
Article Open Access

Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells Retraction in /10.3892/ijo.2023.5547

Feng Tian, Ding Ding, Dandan Li

Pages: 2355-2363 Published online on: 09 April 2015
Article

The Hippo pathway transcriptional co-activator, YAP, confers resistance to cisplatin in human oral squamous cell carcinoma

Kyohei Yoshikawa, Kazuma Noguchi, Yoshiro Nakano, Michiyo Yamamura, Kazuki Takaoka, Tomoko Hashimoto-Tamaoki, Hiromitsu Kishimoto

Pages: 2364-2370 Published online on: 01 April 2015
Article

Proposal of the performance status combined Japan Integrated Staging system in hepatocellular carcinoma complicated with cirrhosis

Hiroki Nishikawa, Ryuichi Kita, Toru Kimura, Masatsugu Endo, Yoshiaki Ohara, Azusa Sakamoto, Sumio Saito, Norihiro Nishijima, Akihiro Nasu, Hideyuki Komekado, Yukio Osaki

Pages: 2371-2379 Published online on: 17 April 2015
Article

Antitumorigenic effect of plumbagin by induction of SH2‑containing protein tyrosine phosphatase 1 in human gastric cancer cells

Moon Kyung Joo, Jong‑Jae Park, Sung Ho Kim, Hyo Soon Yoo, Beom Jae Lee, Hoon Jai Chun, Sang Woo Lee, Young‑Tae Bak

Pages: 2380-2388 Published online on: 26 March 2015
Article

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing

Masataka Takenaka, Motonobu Saito, Reika Iwakawa, Nozomu Yanaihara, Misato Saito, Mamoru Kato, Hitoshi Ichikawa, Tatsuhiro Shibata, Jun Yokota, Aikou Okamoto, Takashi Kohno

Pages: 2389-2398 Published online on: 03 April 2015
Article

Autophagy inhibition enhances sensitivity of endometrial carcinoma cells to paclitaxel

Suiling Liu, Xiaomao Li

Pages: 2399-2408 Published online on: 27 March 2015
Article

Dichloroacetate stimulates changes in the mitochondrial network morphology via partial mitophagy in human SH-SY5Y neuroblastoma cells

David Pajuelo-Reguera, Lukáš Alán, Tomáš Olejár, Petr Ježek

Pages: 2409-2418 Published online on: 06 April 2015
Article

Galectin-9 suppresses the growth of hepatocellular carcinoma via apoptosis in vitro and in vivo

Koji Fujita, Hisakazu Iwama, Teppei Sakamoto, Ryoichi Okura, Kiyoyuki Kobayashi, Jitsuko Takano, Akiko Katsura, Miwa Tatsuta, Emiko Maeda, Shima Mimura, Takako Nomura, Joji Tani, Hisaaki Miyoshi, Asahiro Morishita, Hirohito Yoneyama, Yuka Yamana, Takashi Himoto, Keiichi Okano, Yasuyuki Suzuki, Toshiro Niki, Mitsuomi Hirashima, Tsutomu Masaki

Pages: 2419-2430 Published online on: 30 March 2015
Article

High-mobility-group A2 overexpression provokes a poor prognosis of gastric cancer through the epithelial-mesenchymal transition

Junhyun Lee, Shinjung Ha, Chan-Kwon Jung, Han Hong Lee

Pages: 2431-2438 Published online on: 01 April 2015
Article

Malignant melanoma brain metastases: Treatment results and prognostic factors - a single-center retrospective study

Christian Ostheimer, Caroline Bormann, Eckhard Fiedler, Wolfgang Marsch, Dirk Vordermark

Pages: 2439-2448 Published online on: 20 April 2015
Article

Abnormal expression of Forkhead Box J2 (FOXJ2) suppresses migration and invasion in extrahepatic cholangiocarcinoma and is associated with prognosis

Yong Qiang, Feiran Wang, Sujuan Yan, Haitao Zhang, Lirong Zhu, Zhen Chen, Fang Tu, Dongzhi Wang, Gang Wang, Wei Wang, Zhong Chen

Pages: 2449-2458 Published online on: 07 April 2015
Article

Knockdown of metadherin inhibits angiogenesis in breast cancer

Yan Liu, Xiangnan Kong, Xiaoyan Li, Baojiang Li, Qifeng Yang

Pages: 2459-2466 Published online on: 20 April 2015
Article

Discovery of microarray-identified genes associated with ovarian cancer progression

Xia Liu, Yutao Gao, Bingbing Zhao, Xiaofeng Li, Yi Lu, Jian Zhang, Danrong Li, Li Li, Fuqiang Yin

Pages: 2467-2478 Published online on: 20 April 2015
Article

Establishment and characterization of GCSR1, a multi-drug resistant signet ring cell gastric cancer cell line

Xin Xu, Li-Juan Qian, Xing-Yun Su, Kui-Feng He, Ke-Tao Jin, Lin-Hui Gu, Jian-Guo Feng, Guang-Liang Li, Quan Zhou, Zhen-Zhen Xu, Hao-Hao Wang, Jing Zhang, Jiang Cao, Li-Song Teng

Pages: 2479-2487 Published online on: 16 April 2015
Article

A novel compound against oncogenic Aurora kinase A overcomes imatinib resistance in chronic myeloid leukemia cells

Zi-Jie Long, Le-Xun Wang, Fei-Meng Zheng, Jia-Jie Chen, Yu Luo, Xi-Xiang Tu, Dong-Jun Lin, Gui Lu, Quentin Liu

Pages: 2488-2496 Published online on: 09 April 2015
Article

Long non-coding RNA ANRIL predicts poor prognosis and promotes invasion/metastasis in serous ovarian cancer

Jun-Jun Qiu, Ying-Ying Lin, Jing-Xin Ding, Wei-Wei Feng, Hong-Yan Jin, Ke-Qin Hua

Pages: 2497-2505 Published online on: 31 March 2015
Article

Sodium selenite (Na2SeO3) induces apoptosis through the mitochondrial pathway in CNE-2 nasopharyngeal carcinoma cells

Zhongyi Cui, Caihong Li, Xiangyong Li, Qunzhou Zhang, Yuefei Zhang, Jingjing Shao, Keyuan Zhou

Pages: 2506-2514 Published online on: 17 April 2015
Article

Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas

Carolin Kubelt, Kirsten Hattermann, Susanne Sebens, H. Maximilian Mehdorn, Janka Held-Feindt

Pages: 2515-2525 Published online on: 31 March 2015
Article

Let-7a inhibits growth and migration of breast cancer cells by targeting HMGA1

Kui Liu, Chunfu Zhang, Tao Li, Yanling Ding, Tao Tu, Fangfang Zhou, Wenkai Qi, Huabiao Chen, Xiaochun Sun

Pages: 2526-2534 Published online on: 01 April 2015
Article

Expression of hMOF, but not HDAC4, is responsible for the global histone H4K16 acetylation in gastric carcinoma

Lin Zhu, Jiaxing Yang, Linhong Zhao, Xue Yu, Lingyao Wang, Fei Wang, Yong Cai, Jingji Jin

Pages: 2535-2545 Published online on: 07 April 2015
Article

Translational implication of Kallmann syndrome-1 gene expression in hepatocellular carcinoma

Yuri Tanaka, Mitsuro Kanda, Hiroyuki Sugimoto, Dai Shimizu, Satoshi Sueoka, Hideki Takami, Kazuhiro Ezaka, Ryoji Hashimoto, Yukiyasu Okamura, Naoki Iwata, Chie Tanaka, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Yasuhiro Kodera

Pages: 2546-2554 Published online on: 16 April 2015
Article

Dickkopf-1 induces apoptosis in the JEG3 and BeWo trophoblast tumor cell lines through the mitochondrial apoptosis pathway

Hong Cui, Huan Li, Qiu-Ling Li, Jing Chen, Quan Na, Cai-Xia Liu

Pages: 2555-2561 Published online on: 08 April 2015
Article

B7-H3 silencing inhibits tumor progression of mantle cell lymphoma and enhances chemosensitivity

Wei Zhang, Yanfang Wang, Jing Wang, Fei Dong, Mingxia Zhu, Wenli Wan, Haishen Li, Feifei Wu, Xinxing Yan, Xiaoyan Ke

Pages: 2562-2572 Published online on: 09 April 2015
Article

The novel inhibitor BRM270 downregulates tumorigenesis by suppression of NF-κB signaling cascade in MDR-induced stem like cancer-initiating cells

Raj Kumar Mongre, Simrinder Singh Sodhi, Mrinmoy Ghosh, Jeong Hyun Kim, Nameun Kim, Yang Ho Park, Sung Jin Kim, Yoo Jeong Heo, Neelesh Sharma, Dong Kee Jeong

Pages: 2573-2585 Published online on: 09 April 2015
Article

Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma

Yansheng Wu, Li Zhang, Lun Zhang, Yang Wang, Hui Li, Xiubao Ren, Feng Wei, Wenwen Yu, Ting Liu, Xudong Wang, Xuan Zhou, Jinpu Yu, Xishan Hao

Pages: 2586-2594 Published online on: 22 April 2015
Article

Differential diagnosis of solitary fibrous tumors: A study of 454 soft tissue tumors indicating the diagnostic value of nuclear STAT6 relocation and ALDH1 expression combined with in situ proximity ligation assay

Shaida Ouladan, Marcel Trautmann, Elias Orouji, Wolfgang Hartmann, Sebastian Huss, Reinhard Büttner, Eva Wardelmann

Pages: 2595-2605 Published online on: 20 April 2015
Article

Downregulation of Sp1 is involved in β-lapachone-induced cell cycle arrest and apoptosis in oral squamous cell carcinoma

Young-Joo Jeon, Woong Bang, Jae-Cheon Shin, Seon-Min Park, Jung-Jae Cho, Yung Hyun Choi, Kang Seok Seo, Nag-Jin Choi, Jung-Hyun Shim, Jung-Il Chae

Pages: 2606-2612 Published online on: 20 April 2015
Article

Superoxide dismutase promotes the epithelial-mesenchymal transition of pancreatic cancer cells via activation of the H2O2/ERK/NF-κB axis

Wei Li, Lei Cao, Liang Han, Qinhong Xu, Qingyong Ma

Pages: 2613-2620 Published online on: 27 March 2015
Article

Inhibitory effects of proton beam irradiation on integrin expression and signaling pathway in human colon carcinoma HT29 cells

Byung Geun Ha, Jung-Eun Park, Hyun-Jung Cho, Young-Bin Lim, Yun Hee Shon

Pages: 2621-2628 Published online on: 31 March 2015
Article

The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway

Jianchu Chen, Allen Y. Chen, Haizhi Huang, Xingqian Ye, William D. Rollyson, Haley E. Perry, Kathleen C. Brown, Yon Rojanasakul, Gary O. Rankin, Piyali Dasgupta, Yi Charlie Chen

Pages: 2629-2638 Published online on: 01 April 2015
Article

The role of WWOX tumor suppressor gene in the regulation of EMT process via regulation of CDH1-ZEB1-VIM expression in endometrial cancer

Elżbieta Płuciennik, Magdalena Nowakowska, Karolina Pospiech, Anna Stępień, Mateusz Wołkowicz, Małgorzata Gałdyszyńska, Marta Popęda, Katarzyna Wójcik-Krowiranda, Andrzej Bieńkiewicz, Andrzej K. Bednarek

Pages: 2639-2648 Published online on: 16 April 2015
Article

Docosahexaenoic acid inhibits the invasion of MDA‑MB‑231 breast cancer cells through upregulation of cytokeratin‑1

Vincent Blanckaert, Vincent Kerviel, Alexandra Lépinay, Vanessa Joubert‑Durigneux, Hubert Hondermarck, Benoît Chénais

Pages: 2649-2655 Published online on: 27 March 2015
Article

Hypermethylation of the tumor-suppressor cell adhesion molecule 1 in human papillomavirus-transformed cervical carcinoma cells

Hyun Ju Woo, Sung Jin Kim, Kyung-Joo Song, Sung Soon Kim, Cheol-Hee Yoon, Byeong-Sun Choi, Jee Eun Rhee

Pages: 2656-2662 Published online on: 01 April 2015
Article

Antitumor activity of pamidronate in breast cancer cells transformed by low doses of α-particles and estrogen in vitro

Richard Ponce-Cusi, Gloria M. Calaf

Pages: 2663-2669 Published online on: 07 April 2015
Article

The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells

Hwang-Bo Hyun, Won Sup Lee, Se-Il Go, Arulkumar Nagappan, Cheol Park, Min Ho Han, Su Hyun Hong, Gonsup Kim, Gi Young Kim, Jaehun Cheong, Chung Ho Ryu, Sung Chul Shin, Yung Hyun Choi

Pages: 2670-2678 Published online on: 16 April 2015
Correction Open Access

[Corrigendum] Induction of antigen-specific cytotoxic T lymphocytes by fusion cells generated from allogeneic plasmacytoid dendritic and tumor cells

Shigeo Koido, Sadamu Homma, Shin Kan, Kazuki Takakura, Yoshihisa Namiki, Hiroko Kobayashi, Zensho Ito, Kan Uchiyama, Mikio Kajihara, Seiji Arihiro, Hiroshi Arakawa, Masato Okamoto, Toshifumi Ohkusa, Jianlin Gong, Hisao Tajiri

Pages: 2679-2679 Published online on: 06 April 2015
Journal Cover

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June-2015
Volume 46 Issue 6

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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