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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-December 2011 Volume 2 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

The role of miR-26 in tumors and normal tissues (Review)

Jie Gao, Qing-Guang Liu
Pages: 1019-1023
Published online on: 05 September 2011

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Article Open Access

Fascin expression in dendritic cells and tumor epithelium in thymoma and thymic carcinoma

Junichiro Sato, Masachika Fujiwara, Tomohiro Kawakami, Ayumi Sumiishi, Seiji Sakata, Atsuhiko Sakamoto, Atsushi Kurata
Pages: 1025-1032
Published online on: 17 August 2011

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Article Open Access

Pharmacokinetic and pharmacodynamic profiles of subcutaneous administration of continuous erythropoietin receptor activator in lung cancer patients with anemia induced by chemotherapy

Toshiaki Takahashi, Nobuyuki Yamamoto, Tomohide Tamura, Hideo Kunitoh, Yutaka Nishiwaki, Shunichi Negoro
Pages: 1033-1040
Published online on: 29 August 2011

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Article

Expression of hepatocyte markers in mass-forming peripheral and periductal-infiltrating hilar intrahepatic cholangiocarcinomas

Hiroya Iida, Masaki Hata, Ayako Kakuno, Hiroshi Hirano, Koji Yamanegi, Naoko Yamada, Hideki Ohyama, Nobuyuki Terada, Chiaki Yasui, Naoki Yamanaka, Keiji Nakasho
Pages: 1041-1046
Published online on: 02 September 2011

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Article

Matrix metalloproteinase 3 is a stromal marker for chicken ovarian cancer

Jin Won Choi, Suzie E. Ahn, Deivendran Rengaraj, Hee Won Seo, Whasun Lim, Gwonhwa Song, Jae Yong Han
Pages: 1047-1051
Published online on: 19 August 2011

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Article

Programmed cell death 4 (Pdcd4) expression in colorectal adenocarcinoma: Association with clinical stage

Sung-Chul Lim, Ran Hong
Pages: 1053-1057
Published online on: 22 July 2011

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Article

Differential efficacy of docetaxel according to non‑small cell lung cancer histology and the therapeutic effect of epidermal growth factor receptor tyrosine kinase inhibitors

Satoru Miura, Haruyasu Murakami, Akihiro Tamiya, Sakae Morii, Hiroaki Akamatsu, Akira Ono, Takehito Shukuya, Hirotsugu Kenmotsu, Asuka Tsuya, Yukiko Nakamura, Kyoichi Kaira, Tateaki Naito, Toshiaki Takahashi, Masahiro Endo, Takashi Nakajima, Nobuyuki Yamamoto
Pages: 1059-1064
Published online on: 31 August 2011

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Article

CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer

Hiromi Yasuda, Koji Tanaka, Yoshiki Okita, Toshimitsu Araki, Susumu Saigusa, Yuji Toiyama, Takeshi Yokoe, Shigeyuki Yoshiyama, Aya Kawamoto, Yasuhiro Inoue, Chikao Miki, Masato Kusunoki
Pages: 1065-1071
Published online on: 06 September 2011

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Article

Gastric cavernous hemangioma: A rare case with upper gastrointestinal bleeding

Liang Zong, Ping Chen, Guo Hao Shi, Lei Wang
Pages: 1073-1075
Published online on: 21 July 2011

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Article

Trisomy chromosome 5 is a recurrent cytogenetic lesion in mammary tumors from parous MMTV-erbB-2 transgenic mice

Young Mi Kim, Zhikun Ma, Seungjik Lee, Jiyun Lee, Shibo Li, Xiaohe Yang
Pages: 1077-1081
Published online on: 04 August 2011

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Article

Fusion between cancer cells and myofibroblasts is involved in osteosarcoma

Ling Yu, Weichun Guo, Shenghao Zhao, Fuan Wang, Yong Xu
Pages: 1083-1087
Published online on: 14 July 2011

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Article

Evidence for PTEN-independent Akt activation and Akt-independent p27Kip1 expression in advanced bladder cancer

J. Mundhenk, J. Hennenlotter, L. Zug, S.h. Alloussi, T. Todenhoefer, G. Gakis, S. Aufderklamm, M. Scharpf, U. Kuehs, A. Stenzl, C. Schwentner
Pages: 1089-1093
Published online on: 05 August 2011

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Article

High-level expression of stem cell marker CD133 in clear cell renal cell carcinoma with favorable prognosis

Kyungeun Kim, Hyojin Ihm, Jae Y. Ro, Yong Mee Cho
Pages: 1095-1100
Published online on: 02 August 2011

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Article

Elevated microRNA-126 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in colorectal cancer

Torben Frøstrup Hansen, Claus Lindbjerg Andersen, Boye Schnack Nielsen, Karen-Lise Garm Spindler, Flemming Brandt Sørensen, Jan Lindebjerg, Ivan Brandslund, Anders Jakobsen
Pages: 1101-1106
Published online on: 04 August 2011

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Case Report

Primary retroperitoneal malignant melanoma: A case report

Guo-Bing Liu, Guang-Yao Wu, Prasanna Ghimire, Zai-Peng Zhang
Pages: 1107-1111
Published online on: 29 August 2011

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Article

Acquisition of selective antitumoral effects of recombinant adeno-associated virus by genetically inserting tumor-targeting peptides into capsid proteins

Han Saem Lee, Ji Yun Kim, Won Il Lee, Sung Jin Kim, Min Ji Ko, Sunjoo Jeong, Keerang Park, Han Choe, Heuiran Lee
Pages: 1113-1119
Published online on: 08 August 2011

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Article

RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells

Linhu Ge, Wenlong Shao, Yangde Zhang, Yuan Qiu, Dong  Cui, Donghai Huang, Zhansheng Deng
Pages: 1121-1129
Published online on: 19 August 2011

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Article

Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studies

Semir Vranic, Zoran Gatalica, Zhao-Yi Wang
Pages: 1131-1137
Published online on: 05 August 2011

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Article

Elevated expression of solute carrier family 22 member 18 increases the sensitivity of U251 glioma cells to BCNU

Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Hong Zhang, Jian-Hua Qiu, Zhi-An Zhu
Pages: 1139-1142
Published online on: 04 August 2011

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Article

Vascular endothelial growth factor-A and changes in a tumor-bearing mouse model with Lewis lung cancer

Meng-shu Tsai, Cheng-chi Chang, Min-liang Kuo, Ying-tai  Wu
Pages: 1143-1147
Published online on: 09 August 2011

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Article

Expression of GLUT1 is associated with increasing grade of malignancy in non-invasive and invasive urothelial carcinomas of the bladder

Henning Reis, Stephan Tschirdewahn, Tibor Szarvas, Herbert Rübben, Kurt Werner Schmid, Florian Grabellus
Pages: 1149-1153
Published online on: 29 August 2011

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Article

IGF-IR in patients with advanced colorectal cancer in correlation with certain clinico-morphological factors: Initial report

Adam Kuklinski, Zbigniew Kamocki, Mariusz Koda, Zdzislaw Piotrowski, Stanislaw Sulkowski, Ryszard Lesniewicz, Krystyna Pawlak, Piotr Mysliwiec, Boguslaw Kedra
Pages: 1155-1159
Published online on: 29 August 2011

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Article

Effect of magnetic fluid hyperthermia on lung cancer nodules in a murine model

Runlei Hu, Shenglin Ma, Hu Li, Xianfu Ke, Guoqing Wang, Dongshan Wei, Wei Wang
Pages: 1161-1164
Published online on: 09 August 2011

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Article

Effect of temozolomide on the U-118 glioma cell line

A. Carmo, H. Carvalheiro, I. Crespo, I. Nunes, M. C. Lopes
Pages: 1165-1170
Published online on: 02 September 2011

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Article

Expression of VEGF and MMP-9 and MRI imaging changes in cerebral glioma

Yang Liu, Yang Zhou, Xiu-Shi Zhang, Bao-Zhong Shen
Pages: 1171-1175
Published online on: 17 August 2011

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Article

Overexpression of 14-3-3σ counteracts tumorigenicity by positively regulating p73 in vivo

Cuizhi Geng, Meixiang Sang, Ruiling Yang, Wei Gao, Tao Zhou, Shijie Wang
Pages: 1177-1182
Published online on: 31 August 2011

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Article

The prognostic importance of cathepsin D and E-cadherin in early breast cancer: A single-institution experience

Galia Jacobson-Raber, Irena Lazarev, Victor Novack, Willmosh Mermershtein, Yael Baumfeld, David B. Geffen, Netta Sion-Vardy, Samuel Ariad
Pages: 1183-1190
Published online on: 24 August 2011

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Article

The prolyl isomerase Pin1 is overexpressed in human esophageal cancer

Huawei Jin, Jie Jiang, Lifang Sun, Fangfang Zheng, Chengyan Wu, Lin Peng, Yufen Zhao, Xueji Wu
Pages: 1191-1196
Published online on: 23 August 2011

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Article

Expression of stromal cell-derived factor-1α is an independent risk factor for lymph node metastasis in early gastric cancer

Ik-Chan Song, Zhe-Long Liang, Jung-Chan Lee, Song-Mei Huang, Ha-Yon Kim, Yoon-Suk Oh, Hwan-Jung Yun, Ji-Young Sul, Deog-Yeon Jo, Samyong Kim, Jin-Man Kim, Hyo-Jin Lee
Pages: 1197-1202
Published online on: 19 August 2011

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Article

Impaired nuclear export of tumor-derived c-terminal truncated cyclin D1 mutant in ESCC cancer

Meili Hao, Xiangmei Chen, Ting Zhang, Tao Shen, Qing Xie, Xiujuan Xing, Hongxi Gu, Fengmin Lu
Pages: 1203-1211
Published online on: 02 September 2011

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Article

Effects of TRPM8 on the proliferation and angiogenesis of prostate cancer PC-3 cells in vivo

Guangbin Zhu, Xinghuan Wang, Zhonghua Yang, Hong  Cao, Zhe Meng, Yongzhi Wang, Dong Chen
Pages: 1213-1217
Published online on: 02 September 2011

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Article

Expression of PPARγ and PTEN in human colorectal cancer: An immunohistochemical study using tissue microarray methodology

Mao Song Lin, Jun Xing Huang, Wei Chang Chen, Bao Feng Zhang, Jing Fang, Qiong Zhou, Ying Hu, Heng Jun Gao
Pages: 1219-1224
Published online on: 06 September 2011

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Article

Role of inflammation in oral carcinogenesis (Part I): Histological grading of malignancy using a binary system

Marta Rabello Piva, Lélia Batista De Souza, Paulo Ricardo Saquete Martins-Filho, Rosilene Calazans Soares, Thiago De Santana Santos, Emanuel Sávio De Souza Andrade
Pages: 1225-1231
Published online on: 16 August 2011

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Article

Mutations of the epidermal growth factor receptor gene in NSCLC patients

Bing Han, Xiang Zhou, Rong-Xin Zhang, Wang-Fu Zang, Zhong-Yuan Chen, Huai-Dong Song, Huan-Ying Wan, Cui-Xia Zheng
Pages: 1233-1237
Published online on: 25 July 2011

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Case Report

Long-term efficacy of oral alendronate therapy in an elderly patient with polyostotic fibrous dysplasia: A case report

Gui-dong Li, Akira Ogose, Tetsuo Hotta, Hiroyuki  Kawashima, Takashi  Ariizumi, Yongjun Xu, Naoto Endo
Pages: 1239-1242
Published online on: 02 August 2011

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Article

Consumption of vitamin B6 reduces colonic damage and protein expression of HSP70 and HO-1, the anti-tumor targets, in rats exposed to 1,2-dimethylhydrazine

Tomoko Kayashima, Kenta Tanaka, Yukako Okazaki, Kiminori Matsubara, Noriyuki Yanaka, Norihisa Kato
Pages: 1243-1246
Published online on: 02 August 2011

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Article

A possible predictive marker of progression for hepatocellular carcinoma

Michele Di Stasio, Maria Grazia Volpe, Giovanni Colonna, Melissa Nazzaro, Miriam Polimeno, Stefania Scala, Giuseppe Castello, Susan Costantini
Pages: 1247-1251
Published online on: 09 August 2011

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Article

A phase II study of mitomycin-C and S-1 as third-line chemotherapy in patients with advanced colorectal cancer

Jung Han Kim, Hyeong Su Kim, Dae Ro Choi, Geundoo Jang, Jung Hye Kwon, Ho Young Kim, Joo Young Jung, Hyo Jung Kim, Hun Ho Song, Yun Ho Shin, So Young Jung, Byung Chun Kim, Dae Young Zang
Pages: 1253-1256
Published online on: 27 July 2011

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Article

hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells

Cristina Valls-Bautista, Stéphanie Bougel, Carme  Piñol‑Felis, Joan Viñas-Salas, Jean Benhattar
Pages: 1257-1260
Published online on: 18 August 2011

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Article

Correlation of macrophage migration inhibitory factor gene polymorphism with the risk of early stage cervical cancer and lymphatic metastasis

Suhui Wu, Junfang Lian, Huijuan Tao, Haixia Shang, Li Zhang
Pages: 1261-1267
Published online on: 02 September 2011

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Article

Comparative expression of matrix metalloproteinases in low‑grade mucoepidermoid carcinoma and typical lung cancer

Jiang Fan, Feng-Ying Wu, Lei Wang, Ge-Ning Jiang, Wen Gao
Pages: 1269-1273
Published online on: 18 August 2011

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Article

Runx3 expression in lymph nodes with metastasis is associated with the outcome of gastric cancer patients

Hong-Wei Xu, Feng Ren, Yan-Ming Yu, Cheng-Zhong Cai
Pages: 1275-1279
Published online on: 11 August 2011

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Article

Estradiol induces JNK-dependent apoptosis in glioblastoma cells

Nedret Altiok, Melike Ersoz, Meral Koyuturk
Pages: 1281-1285
Published online on: 17 August 2011

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Article

Novel BRCA1 deleterious mutation (c.1949_1950delTA) in a woman of Senegalese descent with triple-negative early-onset breast cancer

Orland Diez, Amadeu Pelegrí, Neus Gadea, Sara Gutiérrez-Enríquez, Miriam Masas, Anna Tenés, Nina Bosch, Judith Balmaña, Begoña Graña
Pages: 1287-1289
Published online on: 19 August 2011

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Article

HSulf-1 suppresses cell growth and down-regulates Hedgehog signaling in human gastric cancer cells

Hui-Yan Ma, Fang Zhang, Jie Li, Min-Li Mo, Zhao Chen, Lili Liu, Hai-Meng Zhou, Qing Sheng
Pages: 1291-1295
Published online on: 02 September 2011

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Article

Association of insulin-like growth factor-1 with thyroid nodules

Ying‑Jian Liu, Wei Qiang, Xing‑Jun Liu, Li Xu, Hui Guo, Li‑Ping Wu, Bingyin Shi
Pages: 1297-1301
Published online on: 02 September 2011

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Article

Oridonin-induced apoptosis in SW620 human colorectal adenocarcinoma cells

Zhe Ji, Qingjiu Tang, Jinsong Zhang, Yan Yang, Yanfang Liu, Yingjie Pan
Pages: 1303-1307
Published online on: 02 September 2011

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Article

Emetine regulates the alternative splicing of caspase 9 in tumor cells

Danmin Pan, Kritsanapol Boon-Unge, Piyarat Govitrapong, Jianhua Zhou
Pages: 1309-1312
Published online on: 29 August 2011

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Article

Effects of S-1 as a second-line chemotherapy for patients with relapsed pancreatic cancer

Keinosuke Ishido, Yoshikazu Toyoki, Daisuke Kudo, Norihisa Kimura, Daisuke Yamana, Takuya Miura, Shinji Tsutsumi, Takahiro Muroya, Toru Yoshikawa, Hiroshi Ogasawara, Shinnosuke  Yonaiyama, Shunji Narumi, Kenichi Hakamada
Pages: 1313-1317
Published online on: 05 September 2011

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Article

Expression of MMP-3 and TIMP-3 in gastric cancer tissue and its clinical significance

Hong-Qi Liu, Shu Song, Jian-Hua Wang, Shao-Lan Zhang
Pages: 1319-1322
Published online on: 31 August 2011

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Case Report

The rare case of giant cell tumor occuring in the axial skeleton after 15 years of follow-up: Case report

Ye-Soo Park, Jin Kyu Lee, Seung-Wook Baek, Chan-Kum Park
Pages: 1323-1326
Published online on: 02 September 2011

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Article

Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines

Yi Zhang, Lin Cai, Ren-Xiong Wei, Hao Hu, Wei Jin, Xiao-Bin Zhu
Pages: 1327-1332
Published online on: 02 September 2011

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu‑Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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