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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2008 Volume 19 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article

Varied expression and localization of multiple galectins in different cancer cell lines

Arun Satelli, Prema S. Rao, Prem K. Gupta, Paul R. Lockman, Kalkunte S. Srivenugopal, U. Subrahmanyeswara Rao
Pages: 587-594
Published online on: 01 March 2008

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Article

A ginseng saponin metabolite suppresses tumor necrosis factor-α-promoted metastasis by suppressing nuclear factor-κB signaling in murine colon cancer cells

Min-Kyung Choo, Hiroaki Sakurai, Dong-Hyun Kim, Ikuo Saiki
Pages: 595-600
Published online on: 01 March 2008

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Article

Analysis of T-helper type 1 and 2 cells and T-cytotoxic type 1 and 2 cells of sentinel lymph nodes in breast cancer

Katsuhiko Ehi, Sumiya Ishigami, Izumi Masamoto, Yoshikazu Uenosono, Shoji Natsugoe, Takaaki Arigami, Hideo Arima, Yuko Kijima, Heiji Yoshinaka, Shigehiro Yanagita, Tsutomu Kozono, Yawara Funasako, Ikuro Maruyama, Takashi Aikou
Pages: 601-607
Published online on: 01 March 2008

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Article

Expression and cellular localization of TSC-22 in normal salivary glands and salivary gland tumors: Implications for tumor cell differentiation

Yutaka Doi, Hitoshi Kawamata, Yuko Ono, Takahiro Fujimori, Yutaka Imai
Pages: 609-616
Published online on: 01 March 2008

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Article

Breast carcinomas expressing basal markers have poor clinical outcome regardless of estrogen receptor status

Bong Kyung Shin, Youngseok Lee, Jung Bok Lee, Han Kyeom Kim, Jae Bok Lee, Su Jin Cho, Aeree Kim
Pages: 617-625
Published online on: 01 March 2008

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Article

Overexpression of connexin 26 in carcinoma of the pancreas

Naganori Kyo, Hirofumi Yamamoto, Yutaka Takeda, Koji Ezumi, Chew Yee Ngan, Motokazu Terayama, Masakazu Miyake, Ichiro Takemasa, Masataka Ikeda, Yuichiro Doki, Keizo Dono, Mitsugu Sekimoto, Hiroshi Nojima, Morito Monden
Pages: 627-631
Published online on: 01 March 2008

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Article

Up-regulation of the BTG2 gene in TPA- or RA-treated HL-60 cell lines

Byoung-Ok Cho, Yong-Wook Jeong, Seoung-Hoon Kim, Kun Park, Ji-Hye Lee, Gi Ryang Kweon, Jong-Chun Park
Pages: 633-637
Published online on: 01 March 2008

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Article

The progression of gliomas is associated with cancer stem cell phenotype

Doo-Sik Kong, Mi Hyun Kim, Woong-Yang Park, Yeon-Lim Suh, Jung-Il Lee, Kwan Park, Jong Hyun Kim, Do-Hyun Nam
Pages: 639-643
Published online on: 01 March 2008

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Article

Clinicopathological significance of cyclooxygenase-2 expression in hypopharyngeal squamous cell carcinoma

Rieko Goto, Hiroshi Hoshikawa, Takashi Fujii, Kanako Indo, Kunitoshi Yoshino, Katsumi Imaida, Nozomu Mori
Pages: 645-650
Published online on: 01 March 2008

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Article

Prognostic utility of fluorescence in situ hybridization for determining HER2 gene amplification in breast cancer

Makoto Kammori, Rie Kurabayashi, Mitsuhiko Kashio, Akiko Sakamoto, Masataka Yoshimoto, Sadao Amano, Michio Kaminishi, Tetsu Yamada, Kaiyo Takubo
Pages: 651-656
Published online on: 01 March 2008

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Article

Heparanase and vascular endothelial growth factor expression in the progression of oral mucosal melanoma

Rosario S. Rivera, Hitoshi Nagatsuka, Chong Huat Siar, Mehmet Gunduz, Hidetsugu Tsujigiwa, Phuu Pwint Han, Naoki Katase, Ryo Tamamura, Kok Han Ng, Yoshio Naomoto, Motowo Nakajima, Noriyuki Nagai
Pages: 657-661
Published online on: 01 March 2008

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Article

Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer

Sun Jung Kim, Han-Sung Kang, Hye Lim Chang, Yoon Chul Jung, Hyung-Bo Sim, Keun Seok Lee, Jungsil Ro, Eun Sook Lee
Pages: 663-668
Published online on: 01 March 2008

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Article

Inhibition of DLC-1 gene expression by RNA interference in the colon cancer LoVo cell line

Yueling Jin, Xiaoqiang Tian, Yanfang Shang, Peiling Huang
Pages: 669-674
Published online on: 01 March 2008

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Article

Novel biomarker candidates for gastric cancer

Sanghwa Yang, Hyun Cheol Chung
Pages: 675-680
Published online on: 01 March 2008

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Article

Hedgehog signalling in medulloblastoma, glioblastoma and neuroblastoma

Mehdi H. Shahi, Aiala Lorente, Javier S. Castresana
Pages: 681-688
Published online on: 01 March 2008

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Article

BAG-1 inhibits PPARγ-induced cell death, but not PPARγ-induced transcription, cell cycle arrest or differentiation in breast cancer cells

Simon J. Crabb, Angela Hague, Peter W.M. Johnson, Graham Packham
Pages: 689-696
Published online on: 01 March 2008

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Article

PDGFRα/β expression correlates with the metastatic behavior of human colorectal cancer: A possible rationale for a molecular targeting strategy

Thomas C. Wehler, Kirsten Frerichs, Claudine Graf, Daniel Drescher, Katrin Schimanski, Stefan Biesterfeld, Martin R. Berger, Stephan Kanzler, Theodor Junginger, Peter R. Galle, Markus Moehler, Ines Gockel, Carl C. Schimanski
Pages: 697-704
Published online on: 01 March 2008

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Article

Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period

Ken Yamaguchi, Masaki Mandai, Ken Fukuhara, Toshihiro Higuchi, Junzo Hamanishi, Kenji Takakura, Shingo Fujii
Pages: 705-711
Published online on: 01 March 2008

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Article

Decreased expression of RUNX3 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma

Hironori Sugiura, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Yoichiro Mori, Ryo Ogawa, Takeyasu Katada, Koshiro Harata, Yoshitaka Fujii
Pages: 713-719
Published online on: 01 March 2008

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Article

Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression

Youichirou Matsuzaki, Makoto Koyama, Toshiaki Hitomi, Tomoya Yokota, Mayumi Kawanaka, Akiyoshi Nishikawa, Doris Germain, Toshiyuki Sakai
Pages: 721-727
Published online on: 01 March 2008

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Article

Prognostic value of 5-fluorouracil metabolic enzyme genes in Dukes' stage B and C colorectal cancer patients treated with oral 5-fluorouracil-based adjuvant chemotherapy

Hideki Yamada, Hisae Iinuma, Toshiaki Watanabe
Pages: 729-735
Published online on: 01 March 2008

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Article

AP-1 transcription factor decoy reduces the TGF-β1-induced cell growth in scleroderma fibroblasts through inhibition of cyclin E

Jae-We Cho, Young-Chang Cha, Kyu-Suk Lee
Pages: 737-741
Published online on: 01 March 2008

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Article

Cell surface N-glycosylation and sialylation regulate galectin-3-induced apoptosis in human diffuse large B cell lymphoma

Osamu Suzuki, Masafumi Abe
Pages: 743-748
Published online on: 01 March 2008

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Article

K252a is highly effective in suppressing the growth of human endometrial cancer cells, but has little effect on normal human endometrial epithelial cells

Noriyuki Takai, Tami Ueda, Masakazu Nishida, Kaei Nasu, Hisashi Narahara
Pages: 749-753
Published online on: 01 March 2008

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Case Report

Alteration of the chemoresistant gene expression during chemotherapy for colon cancer: A molecular case report

Yuji Toiyama, Yasuhiro Inoue, Junichiro Hiro, Eiki Ojima, Hideki Watanabe, Chikao Miki, Masato Kusunoki
Pages: 755-759
Published online on: 01 March 2008

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Article

Neoadjuvant therapy of gastric cancer with the human monoclonal IgM antibody SC-1: Impact on the immune system

Ulrich Beutner, Udo Lorenz, Bertram Illert, Loretta Rott, Wolfgang Timmermann, H. Peter Vollmers, Hans Konrad Müller-Hermelink, Arnulf Thiede, Karin Ulrichs
Pages: 761-769
Published online on: 01 March 2008

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Article

Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients

Laura Boldrini, Silvia Gisfredi, Silvia Ursino, Marco Lucchi, Giordana Greco, Alfredo Mussi, Gabriella Fontanini
Pages: 771-773
Published online on: 01 March 2008

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Article

Genetic classification of ovarian carcinoma based on microsatellite analysis: Relationship to clinicopathological features and patient survival

Zhang Huan, Kentaro Nakayama, Naomi Nakayama, Masako Ishibashi, Shamima Yeasmin, Atsuko Katagiri, Indri Nuryani Purwana, Kouji Iida, Riruke Maruyama, Manabu Fukumoto, Kohji Miyazaki
Pages: 775-781
Published online on: 01 March 2008

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Article

Disease family history and modification of breast cancer risk in common BRCA2 variants

Ian Jonathan Seymour, Silvia Casadei, Valentina Zampiga, Simonetta Rosato, Rita Danesi, Fabio Falcini, Miria Strada, Nori Morini, Carlo Naldoni, Angelo Paradiso, Stefania Tommasi, Francesco Schittulli, Dino Amadori, Daniele Calistri
Pages: 783-786
Published online on: 01 March 2008

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Article

Adiponectin effects on human breast cancer cells are dependent on 17-β estradiol

Georg H. Pfeiler, Christa Buechler, Markus Neumeier, Andreas Schäffler, Gerd Schmitz, Olaf Ortmann, Oliver Treeck
Pages: 787-793
Published online on: 01 March 2008

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Article

Overexpression of humbug promotes malignant progression in human gastric cancer cells

Jeong-Hyung Lee
Pages: 795-800
Published online on: 01 March 2008

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Article

Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds

Yvonne Bader, Sibylle Madlener, Stephan Strasser, Susanne Maier, Philipp Saiko, Nicole Stark, Ruxandra Popescu, Daniela Huber, Michaela Gollinger, Thomas Erker, Norbert Handler, Akos Szakmary, Walter Jäger, Brigitte Kopp, Ioannis Tentes, Monika Fritzer-Szekeres, Georg Krupitza, Thomas Szekeres
Pages: 801-810
Published online on: 01 March 2008

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Article

Detection of an elevated HER2 expression in MCF-7 breast cancer cells overexpressing estrogen receptor β1

Claus Lattrich, Ingolf Juhasz-Boess, Olaf Ortmann, Oliver Treeck
Pages: 811-817
Published online on: 01 March 2008

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Article

Rhabdoid tumors in children: Prognostic factors in 70 patients diagnosed in Germany

Harald Reinhard, Jennifer Reinert, Rita Beier, Rhoikos Furtwängler, Muhanat Alkasser, Stefan Rutkowski, Michael Frühwald, Ewa Koscielniak, Ivo Leuschner, Peter Kaatsch, Norbert Graf
Pages: 819-823
Published online on: 01 March 2008

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Article

Disruption of the MYC transcriptional function by a small-molecule antagonist of MYC/MAX dimerization

Xiaohong Lu, Peter K. Vogt, Dale L. Boger, John Lunec
Pages: 825-830
Published online on: 01 March 2008

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Article

Phase I trial of PC-Spes2 in advanced hormone refractory prostate cancer

Majid Shabbir, Julie Love, Bruce Montgomery
Pages: 831-835
Published online on: 01 March 2008

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

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Article Number: 140
Published online on: 29 May 2026

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