Journal Articles
Review
Targeting forkhead box transcription factors FOXM1 and FOXO in leukemia (Review)
Hong Zhu
Pages: 1327-1334 Published online on: 23 July 2014
Article
Role of Lifeguard β-isoform in the development of breast cancer
Nadjib Dastagir, Andrea Lazaridis, Khaled Dastagir, Kerstin Reimers, Peter M. Vogt, Vesna Bucan
Pages: 1335-1340 Published online on: 25 July 2014
Article
Phloroglucinol induces apoptosis via apoptotic signaling pathways in HT-29 colon cancer cells
Mi-Hye Kang, In-Hye Kim, Taek-Jeong Nam
Pages: 1341-1346 Published online on: 23 July 2014
Article
TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions
Gun-Hoo Park, Su-Jin Lee, Hyunee Yim, Jae-Ho Han, Hyon J. Kim, Young-Bae Sohn, Jung Min Ko, Seon-Yong Jeong
Pages: 1347-1354 Published online on: 04 August 2014
Article
Invasive micropapillary carcinoma of the extrahepatic bile duct and its malignant potential
Tadashi Yoshizawa, Yoshikazu Toyoki, Hideaki Hirai, Toshihiro Haga, Takahito Toba, Shingo Sakuraba, Kensuke Okano, Yunyan Wu, Hiroko Seino, Satoko Morohashi, Kenichi Hakamada, Hiroshi Kijima
Pages: 1355-1361 Published online on: 07 August 2014
Article
WWOX modulates the gene expression profile in the T98G glioblastoma cell line rendering its phenotype less malignant
Katarzyna Kośla, Magdalena Nowakowska, Karolina Pospiech, Andrzej K. Bednarek
Pages: 1362-1368 Published online on: 17 July 2014
Article
SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling
Huaping Xiong, Jicheng Wang, Hongyu Guan, Jueheng Wu, Ru Xu, Min Wang, Xia Rong, Ke Huang, Jieting Huang, Qiao Liao, Yongshui Fu, Jie Yuan
Pages: 1369-1373 Published online on: 07 August 2014
Article
A comprehensive search for microRNAs with expression profiles modulated by oncogenic KRAS: Potential involvement of miR-31 in lung carcinogenesis
Koji Okudela, Takeshisa Suzuki, Shigeaki Umeda, Yoko Tateishi, Hideaki Mitsui, Yohei Miyagi, Kenichi Ohashi
Pages: 1374-1384 Published online on: 18 July 2014
Article
Mead acid inhibits the growth of KPL-1 human breast cancer cells in vitro and in vivo
Yuichi Kinoshita, Katsuhiko Yoshizawa, Kei Hamazaki, Yuko Emoto, Takashi Yuri, Michiko Yuki, Nobuaki Shikata, Hiroshi Kawashima, Airo Tsubura
Pages: 1385-1394 Published online on: 07 August 2014
Article
Inhibition of Rac1 activity induces G1/S phase arrest through the GSK3/cyclin D1 pathway in human cancer cells
Linna Liu, Hongmei Zhang, Lei Shi, Wenjuan Zhang, Juanli Yuan, Xiang Chen, Juanjuan Liu, Yan Zhang, Zhipeng Wang
Pages: 1395-1400 Published online on: 07 August 2014
Article
Induced IGF-1R activation contributes to gefitinib resistance following combined treatment with paclitaxel, cisplatin and gefitinib in A549 lung cancer cells
Xiaojun Ge, Qingjuan Chen, Yang Ping Wu, Yuchen Zhang, Hongwei Xia, Dandan Yuan, Qi Chen, Weibing Leng, Liang Chen, Qiulin Tang, Xiaohui Pang, Feng Bi
Pages: 1401-1408 Published online on: 15 July 2014
Article
MicroRNA-100 promotes migration and invasion through mammalian target of rapamycin in esophageal squamous cell carcinoma
Naijian Zhang, Hailong Fu, Leilei Song, Youhong Ding, Xiufang Wang, Chao Zhao, Yiqi Zhao, Feng Jiao, Yaping Zhao
Pages: 1409-1418 Published online on: 07 August 2014
Article
KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy
L. S. Yamane, C. Scapulatempo-Neto, L. Alvarenga, C. Z. Oliveira, G. N. Berardinelli, E. Almodova, T. R. Cunha, G. Fava, W. Colaiacovo, A. Melani, J. H. Fregnani, R. M. Reis, D. P. Guimarães
Pages: 1419-1426 Published online on: 18 July 2014
Article
Differential protein expression and novel biomarkers related to 5-FU resistance in a 3D colorectal adenocarcinoma model
Sang-Hak Lee, Jae Kook Nam, Jong-Kook Park, Joo-Ho Lee, Do Sik Min, Hyo-Jeong Kuh
Pages: 1427-1434 Published online on: 18 July 2014
Article
Variability in the measurement of the methylation status of lung cancer-related genes in bronchial secretions
Laura Millares, Antoni Rosell, Laia Setó, José Sanz, Felipe Andreo, Eduard Monsó
Pages: 1435-1440 Published online on: 28 July 2014
Article
Expression of BAG-1 is closely related to cell differentiation and TNM stage in esophageal cancer and its downregulation inhibits the proliferation and invasion of human esophageal carcinoma cells
Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Liu, Fei Xiong, Siwang Wang
Pages: 1441-1446 Published online on: 23 July 2014
Article
Genetic analysis of an orbital metastasis from a primary hepatic neuroendocrine carcinoma
Jacob Ø. Rasmussen, Sarah L. von Holstein, Jan U. Prause, Ben Vainer, Alastair B. Hansen, André Fehr, Göran Stenman, Steffen Heegaard
Pages: 1447-1450 Published online on: 21 July 2014
Article
USP22 promotes epithelial-mesenchymal transition via the FAK pathway in pancreatic cancer cells
Zhen Ning, Aman Wang, Jinxiao Liang, Yunpeng Xie, Jiwei Liu, Qiu Yan, Zhongyu Wang
Pages: 1451-1458 Published online on: 23 July 2014
Article
Notch-1 regulates proliferation and differentiation of human bladder cancer cell lines by inhibiting expression of Krüppel-like factor 4
Xing Ai, Zhuomin Jia, Shuanglin Liu, Jiajun Wang, Xu Zhang
Pages: 1459-1464 Published online on: 23 July 2014
Article
Activation of phosphatidylinositol 3-kinase/Akt signaling mediates sorafenib-induced invasion and metastasis in hepatocellular carcinoma
Haiyong Wang, Litao Xu, Xiaoyan Zhu, Peng Wang, Huiying Chi, Zhiqiang Meng
Pages: 1465-1472 Published online on: 23 July 2014
Article
4-Amino-2-trifluoromethyl-phenyl retinate inhibits the migration of BGC-823 human gastric cancer cells by downregulating the phosphorylation level of MLC II
Anla Hu, Yanyan Yang, Sumei Zhang, Qing Zhou, Wei Wei, Yuan Wang
Pages: 1473-1480 Published online on: 18 July 2014
Article
Paclitaxel-loaded trimethyl chitosan-based polymeric nanoparticle for the effective treatment of gastroenteric tumors
Rong-Feng Song, Xiao-Jun Li, Xiao-Liang Cheng, Ai-Rong Fu, Yan-Hua Wang, Yan-Jun Feng, Yan Xiong
Pages: 1481-1488 Published online on: 21 July 2014
Article
Far from resolved: Stromal cell-based iTRAQ research of muscle-invasive bladder cancer regarding heterogeneity
Peng-Fei Liu, Yong-Hua Wang, Yan-Wei Cao, Hai-Ping Jiang, Xue-Cheng Yang, Xin-Sheng Wang, Hai-Tao Niu
Pages: 1489-1496 Published online on: 18 July 2014
Article
Knockdown of galectin-1 suppresses the growth and invasion of osteosarcoma cells through inhibition of the MAPK/ERK pathway
Jin-Hao Miao, Shu-Qiang Wang, Ming-Hui Zhang, Feng‑Bin Yu, Lei Zhang, Zhong-Xiang Yu, Yong Kuang
Pages: 1497-1504 Published online on: 24 July 2014
Article
RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling
Xu-Hui Zhou, Chao-Qun Yang, Cheng-Lin Zhang, Yang Gao, Hong-Bin Yuan, Ce Wang
Pages: 1505-1512 Published online on: 07 August 2014
Article
Downregulation of phosphoglycerate kinase 1 by shRNA sensitizes U251 xenografts to radiotherapy
Yi-Jun Cheng, Hao Ding, Hua-Qing Du, Hua Yan, Jin-Bing Zhao, Wen-Bin Zhang, Yuan-Jie Zou, Hong-Yi Liu, Hong Xiao
Pages: 1513-1520 Published online on: 23 July 2014
Article
Prostaglandin E2 promotes the cell growth and invasive ability of hepatocellular carcinoma cells by upregulating c-Myc expression via EP4 receptor and the PKA signaling pathway
Shukai Xia, Juan Ma, Xiaoming Bai, Hai Zhang, Shanyu Cheng, Min Zhang, Li Zhang, Mingzhan Du, Yipin Wang, Hai Li, Rong Rong, Feng Shi, Qinyi Yang, Jing Leng
Pages: 1521-1530 Published online on: 07 August 2014
Article
Broussonetia kazinoki modulates the expression of VEGFR-2 and MMP-2 through the inhibition of ERK, Akt and p70S6K‑dependent signaling pathways: Its implication in endothelial cell proliferation, migration and tubular formation
Young-Rak Cho, Jae Hyeon Kim, Jin-Kyu Kim, Eun-Kyung Ahn, Hye-Jin Ko, Jae Kyung In, Sang-Jin Lee, Gyu-Un Bae, Yong Kee Kim, Joa Sub Oh, Dong-Wan Seo
Pages: 1531-1536 Published online on: 04 August 2014
Article
NRP-1 expression is strongly associated with the progression of pituitary adenomas
Sang Won Lee, Jung Eun Lee, Chang Young Yoo, Myoung Seok Ko, Chan Soon Park, Seung-Ho Yang
Pages: 1537-1542 Published online on: 07 August 2014
Article
Effects of lentivirus-mediated RNAi knockdown of NEDD9 on human lung adenocarcinoma cells in vitro and in vivo
Jing-Xia Chang, Feng Gao, Guo-Qiang Zhao, Guo-Jun Zhang
Pages: 1543-1549 Published online on: 22 July 2014
Article
Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma
Xia Ying, Yue Zhao, Jun-Lan Wang, Xia Zhou, Jing Zhao, Chen-Chen He, Xi-Jing Guo, Gui-Hua Jin, Li-Juan Wang, Qing Zhu, Su-Xia Han
Pages: 1550-1556 Published online on: 30 July 2014
Article
Arsenic trioxide induces autophagy and antitumor effects in Burkitt's lymphoma Raji cells
Cai-Li Li, Hu-Lai Wei, Jing Chen, Bei Wang, Bei Xie, Lin-Lan Fan, Lin-Jing Li
Pages: 1557-1563 Published online on: 30 July 2014
Article
AQP5: A novel biomarker that predicts poor clinical outcome in colorectal cancer
Tao Shan, Xijuan Cui, Wei Li, Wanrun Lin, Yiming Li
Pages: 1564-1570 Published online on: 04 August 2014
Article
Prognostic significance of miR-218 in human hepatocellular carcinoma and its role in cell growth
Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Pages: 1571-1577 Published online on: 07 August 2014
Article
Knockdown of ubiquitin associated protein 2-like inhibits the growth and migration of prostate cancer cells
Dong Li, Yiran Huang
Pages: 1578-1584 Published online on: 25 July 2014
Article
Isoalantolactone inhibits constitutive NF-κB activation and induces reactive oxygen species-mediated apoptosis in osteosarcoma U2OS cells through mitochondrial dysfunction
Weihua Di, Muhammad Khan, Azhar Rasul, Meiyan Sun, Yujie Sui, Lili Zhong, Longfei Yang, Qi Zhu, Liangtao Feng, Tonghui Ma
Pages: 1585-1593 Published online on: 30 July 2014
Article
YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis
Jian-Jia Cao, Xiu-Min Zhao, De-Lin Wang, Ke-Hong Chen, Xia Sheng, Wen-Bin Li, Mei-Cai Li, Wu-Jiang Liu, Jiang He
Pages: 1594-1600 Published online on: 22 July 2014
Article
Assessment of insulin-like growth factor 1 receptor as an oncogene in esophageal squamous cell carcinoma and its potential implication in chemotherapy
Wang Ma, Tengfei Zhang, Jian Pan, Ni Shi, Qingxia Fan, Liuxing Wang, Shih Hsin Lu
Pages: 1601-1609 Published online on: 22 July 2014
Article
Curcumin sensitizes glioblastoma to temozolomide by simultaneously generating ROS and disrupting AKT/mTOR signaling
Haitao Yin, Yun Zhou, Cuixia Wen, Chong Zhou, Wei Zhang, Xiang Hu, Lifeng Wang, Chuanwen You, Junfei Shao
Pages: 1610-1616 Published online on: 18 July 2014
Article
PEG-liposomal oxaliplatin combined with nuclear factor-κB inhibitor (PDTC) induces apoptosis in human colorectal cancer cells
Chuang Yang, Zhong-Xue Fu
Pages: 1617-1621 Published online on: 17 July 2014
Article
Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis
Wei Xiang, Ting Jiang, Fengjing Guo, Chen Gong, Kaixiang Yang, Yingxing Wu, Xin Huang, Weiting Cheng, Kai Xu
Pages: 1622-1630 Published online on: 31 July 2014
Article
KPNA2 is a promising biomarker candidate for esophageal squamous cell carcinoma and correlates with cell proliferation
Shouzhi Ma, Xiaohang Zhao
Pages: 1631-1637 Published online on: 04 August 2014
Article
High ALDHdim-expressing CD34+CD38- cells in leukapheresed peripheral blood is a reliable guide for a successful leukemic xenograft model of acute myeloid leukemia
Ji Yoon Lee, Sohye Park, A-Reum Han, Jihyang Lim, Woo-Sung Min, Hee-Je Kim
Pages: 1638-1646 Published online on: 24 July 2014
Article
Synergistic cytotoxic effect of genistein and doxorubicin on drug-resistant human breast cancer MCF-7/Adr cells
Jia-Peng Xue, Geng Wang, Zong-Bin Zhao, Qun Wang, Yun Shi
Pages: 1647-1653 Published online on: 29 July 2014
Article
Contrast-enhanced color Doppler ultrasonography increases diagnostic accuracy for soft tissue tumors
Naoto Oebisu, Manabu Hoshi, Makoto Ieguchi, Jun Takada, Tadashi Iwai, Masahiko Ohsawa, Hiroaki Nakamura
Pages: 1654-1660 Published online on: 04 August 2014
Article
Hotspot mutations in common oncogenes are infrequent in nasopharyngeal carcinoma
Ning Jiang, Na Liu, Fan Yang, Qiming Zhou, Ruixue Cui, Wei Jiang, Qingmei He, Wenfei Li, Ying Guo, Jing Zeng, Jingping Yun, Xinchun Chen, Boping Zhou, Ying Sun, Huiyun Wang, Zhuo G. Chen, Jun Ma
Pages: 1661-1669 Published online on: 01 August 2014
Article
Identification of aspirin analogues that repress NF-κB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo
Ann-Katrin Claudius, Chandra S. Kankipati, Rajagopal S. Kilari, Sadiya Hassan, Kerry Guest, Steven T. Russell, Chris J. Perry, Lesley A. Stark, Iain D. Nicholl
Pages: 1670-1680 Published online on: 31 July 2014
Article
Combined cetuximab and celecoxib treatment exhibits a synergistic anticancer effect on human oral squamous cell carcinoma in vitro and in vivo
Ming Qian, Donghua Qian, Hongyu Jing, Yang Li, Chengyuan Ma, Yanmin Zhou
Pages: 1681-1688 Published online on: 16 July 2014
Article
CIP2A regulates cell proliferation via the AKT signaling pathway in human lung cancer
Ningjing Lei, Bo Peng, Jian-Ying Zhang
Pages: 1689-1694 Published online on: 01 August 2014
Article
Influence of mutation type on prognostic and predictive values of TP53 status in primary breast cancer patients
Petr Dobes, Jan Podhorec, Oldrich Coufal, Andrea Jureckova, Katarina Petrakova, Borivoj Vojtesek, Roman Hrstka
Pages: 1695-1702 Published online on: 21 July 2014
Article
Effect of nitric oxide synthase on multiple drug resistance is related to Wnt signaling in non-small cell lung cancer
Yang Li, Chengyuan Ma, Xu Shi, Zhongmei Wen, Dan Li, Munan Sun, Hui Ding
Pages: 1703-1708 Published online on: 23 July 2014
Article
Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells
Guojun Wang, Yanwei Ye, Xiefu Zhang, Junmin Song
Pages: 1709-1714 Published online on: 30 July 2014
Article
Cancer cells release anaphylatoxin C5a from C5 by serine protease to enhance invasiveness
Hidetoshi Nitta, Yoji Murakami, Yoshihiro Wada, Masatoshi Eto, Hideo Baba, Takahisa Imamura
Pages: 1715-1719 Published online on: 18 July 2014
Article
MicroRNA-145 is a potential prognostic factor of scirrhous type gastric cancer
Yutaka Naito, Kyohei Yasuno, Hiroko Tagawa, Naoya Sakamoto, Naohide Oue, Masakazu Yashiro, Kazuhiro Sentani, Keisuke Goto, Shunsuke Shinmei, Htoo Zarni Oo, Kazuyoshi Yanagihara, Kosei Hirakawa, Wataru Yasui
Pages: 1720-1726 Published online on: 16 July 2014
Article
Cholesterol synthesis inhibitor RO 48-8071 suppresses transcriptional activity of human estrogen and androgen receptor
Benford Mafuvadze, Yayun Liang, Salman M. Hyder
Pages: 1727-1733 Published online on: 15 July 2014
Article
MicroRNA-183 is involved in cell proliferation, survival and poor prognosis in pancreatic ductal adenocarcinoma by regulating Bmi-1
Liang Zhou, Wei-Guo Zhang, De-Sheng Wang, Kai‑Shan Tao, Wen-Jie Song, Ke-Feng Dou
Pages: 1734-1740 Published online on: 01 August 2014
Article
Effect of the PTEN gene on adhesion, invasion and metastasis of osteosarcoma cells
Yong Hu, Shenglin Xu, Wensen Jin, Qiyi Yi, Wei Wei
Pages: 1741-1747 Published online on: 25 July 2014
Article