Journal Articles
Review
Endocrine disruptors and female cancer: Informing the patients (Review)
Lino Del Pup, Alberto Mantovani, Amalia Luce, Carla Cavaliere, Gaetano Facchini, Raffaele Di Francia, Michele Caraglia, Massimiliano Berretta
Pages: 3-11 Published online on: 20 May 2015
Review
The anticancer effect of Huaier (Review)
Xiaojin Song, Yaming Li, Hanwen Zhang, Qifeng Yang
Pages: 12-21 Published online on: 05 May 2015
Article
Identification of diagnostic markers in colorectal cancer via integrative epigenomics and genomics data
Teow Kok-Sin, Norfilza Mohd Mokhtar, Nur Zarina Ali Hassan, Ismail Sagap, Isa Mohamed Rose, Roslan Harun, Rahman Jamal
Pages: 22-32 Published online on: 19 May 2015
Article
AMD3100 reduces CXCR4-mediated survival and metastasis of osteosarcoma by inhibiting JNK and Akt, but not p38 or Erk1/2, pathways in in vitro and mouse experiments
Yu-Xin Liao, Ze-Ze Fu, Cheng-Hao Zhou, Lian-Cheng Shan, Zhuo‑Ying Wang, Fei Yin, Long-Po Zheng, Ying-Qi Hua, Zheng-Dong Cai
Pages: 33-42 Published online on: 19 May 2015
Article
Nuclear lymphocyte-specific protein tyrosine kinase and its interaction with CR6-interacting factor 1 promote the survival of human leukemic T cells
Shahrooz Vahedi, Fu-Yu Chueh, Sujoy Dutta, Bala Chandran, Chao-Lan Yu
Pages: 43-50 Published online on: 19 May 2015
Article
miR-139 and miR-200c regulate pancreatic cancer endothelial cell migration and angiogenesis
Lei Li, Baiwen Li, Dafan Chen, Liyan Liu, Chen Huang, Zhanjun Lu, Lungen Lun, Xinjian Wan
Pages: 51-58 Published online on: 04 May 2015
Article
Effect of sodium/iodide symporter (NIS)-mediated radioiodine therapy on estrogen receptor-negative breast cancer
Chen Yao, Yi Pan, Yongxin Li, Xiangdong Xu, Ying Lin, Wenjian Wang, Shenming Wang
Pages: 59-66 Published online on: 05 May 2015
Article
Sp1-CD147 positive feedback loop promotes the invasion ability of ovarian cancer
Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Pages: 67-76 Published online on: 20 May 2015
Article
High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer Corrigendum in /10.3892/or.2018.6933
Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu
Pages: 77-86 Published online on: 30 April 2015
Article
Ski prevents TGF-β-induced EMT and cell invasion by repressing SMAD-dependent signaling in non-small cell lung cancer Corrigendum in /10.3892/or.2020.7868
Haiping Yang, Lei Zhan, Tianjie Yang, Longqiang Wang, Chang Li, Jun Zhao, Zhe Lei, Xiangdong Li, Hong-Tao Zhang
Pages: 87-94 Published online on: 07 May 2015
Article
Lentiviral-mediated short hairpin RNA silencing of APE1 suppresses hepatocellular carcinoma proliferation and migration: A potential therapeutic target for hepatoma treatment
Zhi-Hua Zheng, Wei Du, Yan-Ju Li, Mei-Qin Gao, Ai-Min Huang, Jing-Feng Liu
Pages: 95-102 Published online on: 13 May 2015
Article
P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway
Jiyi Xia, Xiaolan Yu, Li Tang, Gang Li, Tao He
Pages: 103-110 Published online on: 13 May 2015
Article
MicroRNA-153 functions as a tumor suppressor by targeting SET7 and ZEB2 in ovarian cancer cells
Jun Zhou, Ming Xie, Ying Shi, Baihua Luo, Guanghui Gong, Juanni Li, Junpu Wang, Wenjian Zhao, Yuan Zi, Xiaoying Wu, Jifang Wen
Pages: 111-120 Published online on: 05 May 2015
Article
Epigenetic silencing of DUSP9 induces the proliferation of human gastric cancer by activating JNK signaling
Fang Wu, Tianmin Lv, Gang Chen, Huajun Ye, Wei Wu, Gang Li, Fa-Chao Zhi
Pages: 121-128 Published online on: 20 May 2015
Article
Oncostatin M activates STAT3 to promote endometrial cancer invasion and angiogenesis
Minjiao Zhu, Qi Che, Yun Liao, Huihui Wang, Jingyun Wang, Zheng Chen, Fangyuan Wang, Chenjun Dai, Xiaoping Wan
Pages: 129-138 Published online on: 05 May 2015
Article
Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis
Mun-Ock Kim, Hyun-Sun Lee, Young-Won Chin, Dong-Oh Moon, Jong-Seog Ahn
Pages: 139-146 Published online on: 05 May 2015
Article
Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice
Joong Sun Kim, Yeonghoon Son, Min Ji Bae, Minyoung Lee, Chang Geun Lee, Wol Soon Jo, Sung Dae Kim, Kwangmo Yang
Pages: 147-154 Published online on: 13 May 2015
Article
Prognostic implications of thymidylate synthase gene polymorphisms in patients with advanced small bowel adenocarcinoma treated with first-line fluoropyrimidine-based chemotherapy
Ho-Young Yhim, Sang-Hee Cho, Sam Yong Kim, In Sung Cho, Kyu Taek Lee, Won Sup Lee, Soon Il Lee, Moo Rim Park, Sang-Gon Park, Hye-Suk Han, Yoon Seok Choi, Ik-Joo Chung, Hyun-Jeong Shim, Na-Ri Lee, Eun-Kee Song, Hee Sun Kim, Chang-Yeol Yim
Pages: 155-164 Published online on: 06 May 2015
Article
Combined expression of ezrin and E-cadherin is associated with lymph node metastasis and poor prognosis in breast cancer
Zhaojin Yu, Mingli Sun, Feng Jin, Qinghuan Xiao, Miao He, Huizhe Wu, Jie Ren, Lin Zhao, Haishan Zhao, Weifan Yao, Fengping Shan, Yaming Cao, Minjie Wei
Pages: 165-174 Published online on: 08 May 2015
Article
MicroRNA-195-5p acts as an anti-oncogene by targeting PHF19 in hepatocellular carcinoma
Hui Xu, Yan-Wei Hu, Jia-Yi Zhao, Xiu-Mei Hu, Shu-Fen Li, Yan‑Chao Wang, Ji-Juan Gao, Yan-Hua Sha, Chun-Min Kang, Li Lin, Chuan Huang, Jing-Jing Zhao, Lei Zheng, Qian Wang
Pages: 175-182 Published online on: 07 May 2015
Article
Recombinant hIFN-α2b-BCG inhibits tumor growth in a mouse model of bladder cancer
Erlin Sun, Xiaodong Fan, Lining Wang, Mingde Lei, Xiaodong Zhou, Chunyu Liu, Bingxin Lu, Xuewu Nian, Yan Sun, Ruifa Han
Pages: 183-194 Published online on: 18 May 2015
Article
P2Y2 nucleotide receptor-mediated extracellular signal-regulated kinases and protein kinase C activation induces the invasion of highly metastatic breast cancer cells
So Young Eun, Young Shin Ko, Sang Won Park, Ki Churl Chang, Hye Jung Kim
Pages: 195-202 Published online on: 11 May 2015
Article
MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes
Xu Wen, Jian-Qiu Wu, Wei Peng, Ji-Feng Feng, Jin-Hai Tang
Pages: 203-210 Published online on: 15 May 2015
Article
miR-183 regulates biological behavior in papillary thyroid carcinoma by targeting the programmed cell death 4
Chuankui Wei, Hongming Song, Xiaoguo Sun, Dengfeng Li, Jialu Song, Kaiyao Hua, Lin Fang
Pages: 211-220 Published online on: 11 May 2015
Article
Ligularia fischeri inhibits endothelial cell proliferation, invasion and tube formation through the inactivation of mitogenic signaling pathways and regulation of vascular endothelial cadherin distribution and matrix metalloproteinase expression
Jae Hyeon Kim, Hyeon-Ju Kim, Jin-Kyu Kim, Eun-Kyung Ahn, Hye-Jin Ko, Young-Rak Cho, Sang-Jin Lee, Gyu-Un Bae, Yong Kee Kim, Jong Woo Park, Joa Sub Oh, Dong-Wan Seo
Pages: 221-226 Published online on: 20 May 2015
Article
Interference of STAT 5b expression enhances the chemo-sensitivity of gastric cancer cells to gefitinib by promoting mitochondrial pathway-mediated cell apoptosis
Tao Sun, Yanfei Jia, Dongjie Xiao
Pages: 227-234 Published online on: 19 May 2015
Article
p62 participates in the inhibition of NF-κB signaling and apoptosis induced by sulfasalazine in human glioma U251 cells
Jing Su, Fei Liu, Meihui Xia, Ye Xu, Xiaoning Li, Jinsong Kang, Yulin Li, Liankun Sun
Pages: 235-243 Published online on: 04 May 2015
Article
GnRH participates in the self-renewal of A549-derived lung cancer stem-like cells through upregulation of the JNK signaling pathway
Chi Lu, Ting Huang, Weiqun Chen, Hongda Lu
Pages: 244-250 Published online on: 06 May 2015
Article
Downregulation of MDC1 and 53BP1 by short hairpin RNA enhances radiosensitivity in laryngeal carcinoma cells
Qiheng Gou, Yuxin Xie, Lei Liu, Keqi Xie, Yanxia Wu, Qianqian Wang, Zhu Wang, Ping Li
Pages: 251-257 Published online on: 14 May 2015
Article
Overexpression of neogenin inhibits cell proliferation and induces apoptosis in human MDA-MB-231 breast carcinoma cells
Qingsong Zhang, Fang Liang, Yang Ke, Yanping Huo, Mingchuang Li, Yanyan Li, Junmin Yue
Pages: 258-264 Published online on: 22 May 2015
Article
Inhibitory effects of forkhead box L1 gene on osteosarcoma growth through the induction of cell cycle arrest and apoptosis
Xiaodong Chen, Min Deng, Li Ma, Jiansheng Zhou, Yuzhou Xiao, Xinshe Zhou, Changchun Zhang, Min Wu
Pages: 265-271 Published online on: 11 May 2015
Article
Knockdown of ILK inhibits glioma development via upregulation of E-cadherin and downregulation of cyclin D1
Kebin Zheng, Guangyi Wang, Chunhui Li, Xiaosong Shan, Haipeng Liu
Pages: 272-278 Published online on: 15 May 2015
Article
Melatonin decreases cell proliferation, impairs myogenic differentiation and triggers apoptotic cell death in rhabdomyosarcoma cell lines
Silvia Codenotti, Michela Battistelli, Sabrina Burattini, Sara Salucci, Elisabetta Falcieri, Rita Rezzani, Fiorella Faggi, Marina Colombi, Eugenio Monti, Alessandro Fanzani
Pages: 279-287 Published online on: 19 May 2015
Article
MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells
Seon Hee Kim, Yong Jung Kang, Bokyung Sung, Dong Hwan Kim, Hyun Sook Lim, Hye Rim Kim, Seong Jin Kim, Jeong-Hyun Yoon, Hyung Ryong Moon, Hae Young Chung, Nam Deuk Kim
Pages: 288-294 Published online on: 18 May 2015
Article
Mutant GNAQ promotes cell viability and migration of uveal melanoma cells through the activation of Notch signaling
Honglei Liu, Chunling Lei, Keqin Long, Xinguang Yang, Zhaoliang Zhu, Lihua Zhang, Jun Liu
Pages: 295-301 Published online on: 05 May 2015
Article
Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells
Xukui Zhang, Luming Zheng, Yinggang Sun, Tianxiao Wang, Baocheng Wang
Pages: 302-310 Published online on: 15 May 2015
Article
miR-34a inhibits the migration and invasion of esophageal squamous cell carcinoma by targeting Yin Yang-1
Jihua Nie, Xin Ge, Yangyang Geng, Han Cao, Wei Zhu, Yang Jiao, Jinchang Wu, Jundong Zhou, Jianping Cao
Pages: 311-317 Published online on: 07 May 2015
Article
Microarray analysis of the aberrant microRNA expression pattern in gliomas of different grades
Xiao-Peng Zhu, Ke-Jie Mou, Qing-Fu Xu, Jun-Hai Tang, Guo-Hao Huang, Jian-Ping Xu, Guang-Hui Li, Si-Jin Ai, Jean-Phillippe Hugnot, Zheng Zhou, Sheng-Qing Lv
Pages: 318-324 Published online on: 06 May 2015
Article
Integrated analysis of differentially expressed mRNAs and miRNAs between hepatocellular carcinoma and their matched adjacent normal liver tissues
Bing Gao, Shufang Ning, Jilin Li, Haizhou Liu, Wene Wei, Feixiang Wu, Yanping Tang, Yan Feng, Kezhi Li, Litu Zhang
Pages: 325-333 Published online on: 08 May 2015
Article
M410, a combretastatin A4 analogue, disrupts microtubules and inhibits HIF-1α in human breast cancer cells
Hang Yang, Qing Xia, Yong Zou, Kefeng Wang, Wenqi Jiang, Yuchen Cai
Pages: 334-340 Published online on: 12 May 2015
Article
RNF8 plays an important role in the radioresistance of human nasopharyngeal cancer cells in vitro
Maoxin Wang, Xianming Chen, Hui Chen, Xian Zhang, Jianzhong Li, Hongxun Gong, Chen Shiyan, Fan Yang
Pages: 341-349 Published online on: 07 May 2015
Article
Downregulation of CD9 promotes pancreatic cancer growth and metastasis through upregulation of epidermal growth factor on the cell surface
Maochun Tang, Guojian Yin, Feng Wang, Hua Liu, Shu Zhou, Jianbo Ni, Congying Chen, Yingqun Zhou, Yan Zhao
Pages: 350-358 Published online on: 07 May 2015
Article
Participation of autophagy in the cytotoxicity against breast cancer cells by cisplatin
Meng Shen, Wei-Ming Duan, Meng-Yao Wu, Wen-Jie Wang, Lu Liu, Meng-Dan Xu, Jie Zhu, Dao-Ming Li, Qi Gui, Lian Lian, Fei-Ran Gong, Kai Chen, Wei Li, Min Tao
Pages: 359-367 Published online on: 25 May 2015
Article
miR-193b acts as a cisplatin sensitizer via the caspase-3-dependent pathway in HCC chemotherapy
Wenjun Yin, Yuehua Nie, Zhiwei Zhang, Liming Xie, Xiusheng He
Pages: 368-374 Published online on: 19 May 2015
Article
Quercetin-induced autophagy flux enhances TRAIL-mediated tumor cell death
Ji-Hong Moon, Seong Kug Eo, John Hwa Lee, Sang-Youel Park
Pages: 375-381 Published online on: 19 May 2015
Article
Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey
Gabriella Macchia, Aldo Sainato, Renato Talamini, Giovanni Boz, Almalina Bacigalupo, Luciana Caravatta, Michele Fiore, Maria Luisa Friso, Vincenzo Fusco, Marco Lupattelli, Giovanna Mantello, Gian Carlo Mattiucci, Najla Slim, Piera Sciacero, Lucia Turri, Vincenzo Valentini, Alessio Giuseppe Morganti, Domenico Genovesi
Pages: 382-390 Published online on: 06 May 2015
Article
Dissecting the roles of Ephrin-A3 in malignant peripheral nerve sheath tumor by TALENs
Zhengguang Wang, Zhendong Liu, Bo Liu, Gengyan Liu, Song Wu
Pages: 391-398 Published online on: 08 May 2015
Article
MicroRNA-204 inhibits proliferation, migration, invasion and epithelial-mesenchymal transition in osteosarcoma cells via targeting Sirtuin 1 Retraction in /10.3892/or.2021.8098
Ying Shi, Jianjun Huang, Jun Zhou, Ying Liu, Xiaodan Fu, Yimin Li, Gang Yin, Jifang Wen
Pages: 399-406 Published online on: 19 May 2015
Article
Antitumor activity of YM155, a selective survivin suppressant, in combination with cisplatin in hepatoblastoma
Ying Yu, Xiaosu Zhao, Yu Zhang, Yanling Kang, Jiaqi Wang, Yingchun Liu
Pages: 407-414 Published online on: 05 May 2015
Article
Apoptosis inhibitor TRIAP1 is a novel effector of drug resistance
Caroline Adams, Giulia Cazzanelli, Sabeena Rasul, Ben Hitchinson, Yunhui Hu, R. Charles Coombes, Selina Raguz, Ernesto Yagüe
Pages: 415-422 Published online on: 19 May 2015
Article
RON alternative splicing regulation in primary ovarian cancer
Sebastian Mayer, Marc Hirschfeld, Markus Jaeger, Susanne Pies, Severine Iborra, Thalia Erbes, Elmar Stickeler
Pages: 423-430 Published online on: 19 May 2015
Article
Delphinidin induces cytotoxicity and potentiates cytocidal effect in combination with arsenite in an acute promyelocytic leukemia NB4 cell line
Bo Yuan, Saki Okusumi, Yuta Yoshino, Chihiro Moriyama, Sachiko Tanaka, Toshihiko Hirano, Norio Takagi, Hiroo Toyoda
Pages: 431-438 Published online on: 08 May 2015
Article
Krüppel-like factor 4 modulates the migration and invasion of hepatoma cells by suppressing TIMP-1 and TIMP-2
Ming-Ta Sung, Hui-Tzu Hsu, Chih-Chun Lee, Hsin-Chen Lee, Ying‑Ju Kuo, Kate Hua, Cheng-Yuan Hsia, Chin-Wen Chi
Pages: 439-446 Published online on: 08 May 2015
Article
Endocannabinoid and ceramide levels are altered in patients with colorectal cancer
Ling Chen, Huixia Chen, Yanting Li, Lei Li, Yan Qiu, Jie Ren
Pages: 447-454 Published online on: 12 May 2015
Article
The histone methyltransferase EZH2 promotes mammary stem and luminal progenitor cell expansion, metastasis and inhibits estrogen receptor-positive cellular differentiation in a model of basal breast cancer
Jianchun Wu, David L. Crowe
Pages: 455-460 Published online on: 21 May 2015
Article
MicroRNA-370 inhibits the progression of non-small cell lung cancer by downregulating oncogene TRAF4
Tianjun Chen, Fei Gao, Sifang Feng, Tian Yang, Mingwei Chen
Pages: 461-468 Published online on: 13 May 2015
Article
Targeting of the EGFR/β1 integrin connecting proteins PINCH1 and Nck2 radiosensitizes three-dimensional SCC cell cultures
Lydia Rossow, Iris Eke, Ellen Dickreuter, Nils Cordes
Pages: 469-476 Published online on: 25 May 2015
Article
The combined use of Camellia sinensis and metronomic zoledronate in 4T1 mouse carcinoma against tumor growth and metastasis
Ke-Wang Luo, Grace Gar-Lee Yue, Chun-Hay Ko, Si Gao, Julia Kin-Ming Lee, Gang Li, Kwok-Pui Fung, Ping-Chung Leung, Clara Bik-San Lau
Pages: 477-487 Published online on: 20 May 2015
Article
Concentrative nucleoside transporter 3 as a prognostic indicator for favorable outcome of t(8;21)-positive acute myeloid leukemia patients after cytarabine-based chemotherapy
Ju Han Song, Kyung-Min Cho, Hyeoung-Joon Kim, Yeo-Kyeoung Kim, Nan Young Kim, Hee-Je Kim, Tae-Hyang Lee, Seung Yong Hwang, Tae Sung Kim
Pages: 488-494 Published online on: 07 May 2015
Article
3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation
Khalda Fadlalla, Ramy Elgendy, Ebony Gilbreath, Satyanarayana R. Pondugula, Teshome Yehualaeshet, Mahmoud Mansour, Tesfaye Serbessa, Upender Manne, Temesgen Samuel
Pages: 495-503 Published online on: 11 May 2015
Article
Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine
Shin Kan, Shigeo Koido, Masato Okamoto, Kazumi Hayashi, Masaki Ito, Yuko Kamata, Hideo Komita, Takefumi Ishidao, Eijiro Nagasaki, Sadamu Homma
Pages: 504-510 Published online on: 12 May 2015
Article
Daintain/AIF-1 accelerates the activation of insulin-like growth factor-1 receptor signaling pathway in HepG2 cells
Shaohui Jia, Zhongxia Du, Hua Jiang, Xingyuan Huang, Zhengwang Chen, Ning Chen
Pages: 511-517 Published online on: 20 May 2015
Article
Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells
Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Kirit Pindolia, Subhash C. Gautam
Pages: 518-524 Published online on: 19 May 2015
Article
