Journal Articles
Review
Genetics, diagnosis and management of colorectal cancer (Review)
Marina De Rosa, Ugo Pace, Daniela Rega, Valeria Costabile, Francesca Duraturo, Paola Izzo, Paolo Delrio
Pages: 1087-1096 Published online on: 03 July 2015
Review
Nanotechnology applications in hematological malignancies (Review)
Ahmed Samir, Basma M. Elgamal, Hala Gabr, Hatem E. Sabaawy
Pages: 1097-1105 Published online on: 02 July 2015
Review
Natural and adaptive IgM antibodies in the recognition of tumor-associated antigens of breast cancer (Review)
Mariana Díaz-Zaragoza, Ricardo Hernández-Ávila, Rubí Viedma‑Rodríguez, Diego Arenas-Aranda, Pedro Ostoa-Saloma
Pages: 1106-1114 Published online on: 30 June 2015
Article
Effects of daidzein in regards to cytotoxicity in vitro, apoptosis, reactive oxygen species level, cell cycle arrest and the expression of caspase and Bcl-2 family proteins
Bing-Jie Han, Wei Li, Guang-Bin Jiang, Shang-Hai Lai, Cheng Zhang, Chuan-Chuan Zeng, Yun-Jun Liu
Pages: 1115-1120 Published online on: 14 July 2015
Article
Knockdown of SOX18 inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells
Guiming Wang, Zhigang Wei, Hongyan Jia, Wenbo Zhao, Gaochao Yang, Haoliang Zhao
Pages: 1121-1128 Published online on: 07 July 2015
Article
Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway
Xiaolong Yu, Xin Zhou, Changlin Fu, Qiang Wang, Tao Nie, Fan Zou, Runsheng Guo, Hucheng Liu, Bin Zhang, Min Dai
Pages: 1129-1136 Published online on: 13 July 2015
Article
Prognostic implication of PTPRH hypomethylation in non-small cell lung cancer
Takashi Sato, Kenzo Soejima, Eri Arai, Junko Hamamoto, Hiroyuki Yasuda, Daisuke Arai, Kota Ishioka, Keiko Ohgino, Katsuhiko Naoki, Takashi Kohno, Koji Tsuta, Shun-Ichi Watanabe, Yae Kanai, Tomoko Betsuyaku
Pages: 1137-1145 Published online on: 25 June 2015
Article
Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance Corrigendum in /or/35/1/602
Loredana Vesci, Valeria Carollo, Giuseppe Roscilli, Luigi Aurisicchio, Fabiana Fosca Ferrara, Luigi Spagnoli, Rita De Santis
Pages: 1146-1152 Published online on: 24 June 2015
Article
miR-130a acts as a potential diagnostic biomarker and promotes gastric cancer migration, invasion and proliferation by targeting RUNX3
Hong Jiang, Wei-Wei Yu, Lu-Lu Wang, Yang Peng
Pages: 1153-1161 Published online on: 01 July 2015
Article
Green tea polyphenol epigallocatechin-O-gallate induces cell death by acid sphingomyelinase activation in chronic myeloid leukemia cells
Yuhui Huang, Motofumi Kumazoe, Jaehoon Bae, Shuhei Yamada, Mika Takai, Shiori Hidaka, Shuya Yamashita, Yoonhee Kim, Yeongseon Won, Motoki Murata, Shuntaro Tsukamoto, Hirofumi Tachibana
Pages: 1162-1168 Published online on: 26 June 2015
Article
Hepatic stellate cells promote upregulation of epithelial cell adhesion molecule and epithelial-mesenchymal transition in hepatic cancer cells
Teruya Nagahara, Hidenori Shiraha, Hiroaki Sawahara, Daisuke Uchida, Yasuto Takeuchi, Masaya Iwamuro, Junro Kataoka, Shigeru Horiguchi, Takeshi Kuwaki, Hideki Onishi, Shinichiro Nakamura, Akinobu Takaki, Kazuhiro Nouso, Kazuhide Yamamoto
Pages: 1169-1177 Published online on: 13 July 2015
Article
Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling
Soojung Jin, Hee Jung Yun, Hyun Young Jeong, You Na Oh, Hyun‑Jin Park, Seung-Geun Yun, Byung Woo Kim, Hyun Ju Kwon
Pages: 1178-1184 Published online on: 24 June 2015
Article
Inhibitory effects of valproic acid in DNA double-strand break repair after irradiation in esophageal squamous carcinoma cells
Naoki Makita, Itasu Ninomiya, Tomoya Tsukada, Koichi Okamoto, Shinichi Harada, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi, Katsunobu Oyama, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Tetsuo Ohta
Pages: 1185-1192 Published online on: 26 June 2015
Article
Activation of ARK5/miR-1181/HOXA10 axis promotes epithelial-mesenchymal transition in ovarian cancer
Hai-Yan Zhang, Jian-Hua Li, Guang Li, Su-Rong Wang
Pages: 1193-1202 Published online on: 07 July 2015
Article
HOXA1 enhances the cell proliferation, invasion and metastasis of prostate cancer cells
Haitao Wang, Guanzhong Liu, Dan Shen, Huamao Ye, Jinming Huang, Li Jiao, Yinghao Sun
Pages: 1203-1210 Published online on: 26 June 2015
Article
Expression of DNA ligase IV is linked to poor prognosis and characterizes a subset of prostate cancers harboring TMPRSS2:ERG fusion and PTEN deletion
Katharina Grupp, Laura Roettger, Martina Kluth, Claudia Hube-Magg, Ronald Simon, Patrick Lebok, Sarah Minner, Maria Christina Tsourlakis, Christina Koop, Markus Graefen, Meike Adam, Alexander Haese, Corinna Wittmer, Guido Sauter, Waldemar Wilczak, Hartwig Huland, Thorsten Schlomm, Stefan Steurer, Till Krech
Pages: 1211-1220 Published online on: 25 June 2015
Article
Suppression of KLF8 induces cell differentiation and sensitizes colorectal cancer to 5-fluorouracil
Xinpeng Shi, Xiaoyong Luo, Qingqing Yan, Wenjing Zhang, Yao Wu, Mengnan Zhang, Jinjun Zhao, Ying Peng, Ye Chen, Yali Zhang, Cunlong Chen, Tianming Cheng, Chudi Chen, Side Liu, Yang Bai, Jide Wang
Pages: 1221-1230 Published online on: 30 June 2015
Article
CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer
Tiing Jen Loh, Heegyum Moon, Sunghee Cho, Hana Jang, Yong Chao Liu, Hongmei Tai, Da-Woon Jung, Darren R. Williams, Hey-Ran Kim, Myung-Geun Shin, D. Joshua Liao, Jianhua Zhou, Wei Shi, Xuexiu Zheng, Haihong Shen
Pages: 1231-1238 Published online on: 06 July 2015
Article
ZGDHu-1 and fludarabine have a synergistic effect on apoptosis of chronic lymphocytic leukemia cells
Liannv Qiu, Jinlin Liu, Zhenni Wang, Weixiao Hu, Qiang Huang, Yonglie Zhou
Pages: 1239-1248 Published online on: 08 July 2015
Article
A secretomic study on human hepatocellular carcinoma multiple drug-resistant cell lines
Yi Xiang, Yi Liu, Yixuan Yang, Huaidong Hu, Peng Hu, Hong Ren, Dazhi Zhang
Pages: 1249-1260 Published online on: 03 July 2015
Article
Ursodeoxycholic acid effectively kills drug-resistant gastric cancer cells through induction of autophagic death
Sung-Chul Lim, Song Iy Han
Pages: 1261-1268 Published online on: 24 June 2015
Article
Circulating classical CD14++CD16- monocytes predict shorter time to initial treatment in chronic lymphocytic leukemia patients: Differential effects of immune chemotherapy on monocyte-related membrane and soluble forms of CD163
Izabela Lapuc, Lukasz Bolkun, Andrzej Eljaszewicz, Malgorzata Rusak, Ewa Luksza, Paulina Singh, Paula Miklasz, Jaroslaw Piszcz, Katarzyna Ptaszynska‑Kopczynska, Malgorzata Jasiewicz, Karol Kaminski, Milena Dabrowska, Anna Bodzenta-Lukaszyk, Janusz Kloczko, Marcin Moniuszko
Pages: 1269-1278 Published online on: 26 June 2015
Article
RITA enhances irradiation-induced apoptosis in p53-defective cervical cancer cells via upregulation of IRE1α/XBP1 signaling
Hong Zhu, Muyasha Abulimiti, Huan Liu, Xiang-Jiang Su, Cai-Hong Liu, Hai-Ping Pei
Pages: 1279-1288 Published online on: 25 June 2015
Article
Honokiol exhibits enhanced antitumor effects with chloroquine by inducing cell death and inhibiting autophagy in human non-small cell lung cancer cells
Xiaoqin Lv, Fang Liu, Yue Shang, Shu-Zhen Chen
Pages: 1289-1300 Published online on: 29 June 2015
Article
Identification of genes and long non-coding RNAs associated with the pathogenesis of gastric cancer
Zhiwei Zhao, Yan Song, Daxun Piao, Tianyou Liu, Liangliang Zhao
Pages: 1301-1310 Published online on: 14 July 2015
Article
Antitumor activity of a 2-pyridinecarboxaldehyde 2-pyridinecarboxylic acid hydrazone copper complex and the related mechanism
Yingli Yang, Tengfei Huang, Sufeng Zhou, Yun Fu, Youxun Liu, Yanbin Yuan, Qiongqing Zhang, Shaoshan Li, Changzheng Li
Pages: 1311-1318 Published online on: 26 June 2015
Article
Astrocyte elevated gene-1 regulates CCL3/CCR5-induced epithelial-to-mesenchymal transition via Erk1/2 and Akt signaling in cardiac myxoma
Ping Shi, Changcun Fang, Xinyan Pang
Pages: 1319-1326 Published online on: 25 June 2015
Article
Nuclear vasohibin-2 promotes cell proliferation by inducing G0/G1 to S phase progression
Qianqian Ge, Jia Zhou, Min Tu, Xiaofeng Xue, Zhanjun Li, Zipeng Lu, Jishu Wei, Guoxin Song, Jianmin Chen, Feng Guo, Kuirong Jiang, Yi Miao, Wentao Gao
Pages: 1327-1336 Published online on: 13 July 2015
Article
Expression and activity analysis of a new fusion protein targeting ovarian cancer cells
Manman Su, Weiqin Chang, Dingding Wang, Manhua Cui, Yang Lin, Shuying Wu, Tianmin Xu
Pages: 1337-1344 Published online on: 09 July 2015
Article
Binding of MMP-9-degraded fibronectin to β6 integrin promotes invasion via the FAK-Src-related Erk1/2 and PI3K/Akt/Smad-1/5/8 pathways in breast cancer
Wentong Li, Zhijun Liu, Chunling Zhao, Limin Zhai
Pages: 1345-1352 Published online on: 02 July 2015
Article
The tumor-suppressive role of BATF2 in esophageal squamous cell carcinoma
Tianci Han, Zhiyong Wang, Yang Yang, Tianci Shu, Weinan Li, Dali Liu, Peiwen Li, Ruiqun Qi, Yi Ren, Li Li, Hong Liu, Shuguang Zhang, Lin Zhang
Pages: 1353-1360 Published online on: 26 June 2015
Article
Concentration-dependent differential effects of an epothilone analog on cell cycle and p53 signaling
Fan An, Wei-Jie Zhao, Li Tang, Rong-Guo Qiu
Pages: 1361-1368 Published online on: 14 July 2015
Article
GALC gene is downregulated by promoter hypermethylation in Epstein-Barr virus-associated nasopharyngeal carcinoma
Yinghai Zhao, Ying Guo, Zhijing Wang, Zebin Xiao, Rong Li, Aihua Luo, Changli Wu, Zhiliang Jing, Ning Sun, Xiaoyi Chen, Haijun Du, Yi Zeng
Pages: 1369-1378 Published online on: 14 July 2015
Article
A limited overlap between intratumoral distribution of 1-(5-fluoro-5-deoxy-α-D-arabinofuranosyl)-2-nitroimidazole and copper-diacetyl-bis[N(4)-methylthiosemicarbazone]
Takako Furukawa, Qinghua Yuan, Zhao-Hui Jin, Winn Aung, Yukie Yoshii, Sumitaka Hasegawa, Hiroko Endo, Masahiro Inoue, Ming‑Rong Zhang, Yasuhisa Fujibayashi, Tsuneo Saga
Pages: 1379-1387 Published online on: 25 June 2015
Article
Evodiamine inhibits the proliferation of human osteosarcoma cells by blocking PI3K/Akt signaling
Zi-Jun Meng, Nian Wu, Yang Liu, Ke-Jie Shu, Xiang Zou, Ran-Xi Zhang, Chang-Jun Pi, Bai-Cheng He, Zhen-Yong Ke, Liang Chen, Zhong-Liang Deng, Liang-Jun Yin
Pages: 1388-1396 Published online on: 25 June 2015
Article
High expression of transforming acidic coiled coil-containing protein 3 strongly correlates with aggressive characteristics and poor prognosis of gastric cancer
Miao Yun, Jian Rong, Zhi-Rui Lin, Yu-Long He, Jia-Xing Zhang, Zhen-Wei Peng, Lin-Quan Tang, Mu-Sheng Zeng, Qian Zhong, Sheng Ye
Pages: 1397-1405 Published online on: 30 June 2015
Article
SPARC ectopic overexpression inhibits growth and promotes programmed cell death in acute myeloid leukemia transformed from myelodysplastic syndrome cells, alone and in combination with Ara-C treatment
Qing Nian, Jianxiang Chi, Qing Xiao, Chunmei Wei, Paul Costeas, Zesong Yang, Lin Liu, Li Wang
Pages: 1406-1414 Published online on: 08 July 2015
Article
miR-99b promotes metastasis of hepatocellular carcinoma through inhibition of claudin 11 expression and may serve as a prognostic marker
Jianhui Yang, Xiwu Liu, Xiaohua Yuan, Zhiming Wang
Pages: 1415-1423 Published online on: 02 July 2015
Article
PIG3 plays an oncogenic role in papillary thyroid cancer by activating the PI3K/AKT/PTEN pathway
Jinye Xu, Junbo Cai, Xiaoyan Jin, Jingjin Yang, Qinyan Shen, Xiaofei Ding, Yong Liang
Pages: 1424-1430 Published online on: 30 June 2015
Article
Knockdown of zinc transporter ZIP5 (SLC39A5) expression significantly inhibits human esophageal cancer progression
Jing Jin, Zhongxin Li, Jianghui Liu, Yan Wu, Xing Gao, Yutong He
Pages: 1431-1439 Published online on: 01 July 2015
Article
Aquaporin 1 promotes the proliferation and migration of lung cancer cell in vitro
Xiaobai Wei, Jingcheng Dong
Pages: 1440-1448 Published online on: 03 July 2015
Article
Topical treatment with Xiaozheng Zhitong Paste alleviates bone cancer pain by inhibiting proteinase-activated receptor 2 signaling pathway
Yanju Bao, Gaimei Wang, Yebo Gao, Maobo Du, Liping Yang, Xiangying Kong, Honggang Zheng, Wei Hou, Baojin Hua
Pages: 1449-1459 Published online on: 24 June 2015
Article
REV3L modulates cisplatin sensitivity of non-small cell lung cancer H1299 cells
Wenjie Wang, Wenjiong Sheng, Chenxiao Yu, Jianping Cao, Jundong Zhou, Jinchang Wu, Huojun Zhang, Shuyu Zhang
Pages: 1460-1468 Published online on: 09 July 2015
Article
Umbilical cord-derived mesenchymal stem cells promote proliferation and migration in MCF-7 and MDA-MB-231 breast cancer cells through activation of the ERK pathway
Tao Li, Chunfu Zhang, Yanling Ding, Wei Zhai, Kui Liu, Fan Bu, Tao Tu, Lingxian Sun, Wei Zhu, Fangfang Zhou, Wenkai Qi, Jiabo Hu, Huabiao Chen, Xiaochun Sun
Pages: 1469-1477 Published online on: 03 July 2015
Article
Low-dose UVB irradiation prevents MMP2-induced skin hyperplasia by inhibiting inflammation and ROS
Lin Dang, Yan Wang, Yadong Xue, Lei He, Yuzhen Li, Jikui Xiong
Pages: 1478-1486 Published online on: 24 June 2015
Article
Tanshinone IIA enhances bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in nuclei and mitochondria
Haiyang Jiang, Lei Zhao, Xiaoshen Dong, Anning He, Caiwei Zheng, Magnus Johansson, Anna Karlsson, Xinyu Zheng
Pages: 1487-1493 Published online on: 02 July 2015
Article
STC2 overexpression mediated by HMGA2 is a biomarker for aggressiveness of high-grade serous ovarian cancer
Jingjing Wu, Maode Lai, Changshun Shao, Jian Wang, Jian-Jun Wei
Pages: 1494-1502 Published online on: 09 July 2015
Article
Hypomethylated Rab27b is a progression-associated prognostic biomarker of glioma regulating MMP-9 to promote invasion
Hongjun Wang, Yongzhi Wang, Zhaoshi Bao, Chuanbao Zhang, Yanwei Liu, Jinquan Cai, Chuanlu Jiang
Pages: 1503-1509 Published online on: 13 July 2015
Article
Lentivirus-mediated gene silencing of NOB1 suppresses non-small cell lung cancer cell proliferation
Weiyi Huang, Weiqing Zhong, Jun Xu, Benhua Su, Guanghui Huang, Jiajun Du, Qi Liu
Pages: 1510-1516 Published online on: 14 July 2015
Article
Flavonoids isolated from Citrus platymamma induce mitochondrial-dependent apoptosis in AGS cells by modulation of the PI3K/AKT and MAPK pathways
Ho Jeong Lee, Arulkumar Nagappan, Hyeon Soo Park, Gyeong Eun Hong, Silvia Yumnam, Suchismita Raha, Venu Venkatarame Gowda Saralamma, Won Sup Lee, Eun Hee Kim, Gon Sup Kim
Pages: 1517-1525 Published online on: 10 July 2015
Article
Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells
Alan P. Lombard, Rebecca M. Lim, Rachel M. Nakagawa, Kathleen D. Vidallo, Stephen J. Libertini, Alexander J. Platero, Maria Mudryj
Pages: 1526-1532 Published online on: 09 July 2015
Article
Antitumor effects of a drug combination targeting glycolysis, glutaminolysis and de novo synthesis of fatty acids
Diana Cervantes-Madrid, Alfonso Dueñas-González
Pages: 1533-1542 Published online on: 24 June 2015
Article
ERK/GSK3β signaling is involved in atractylenolide I-induced apoptosis and cell cycle arrest in melanoma cells
Yan Ye, Xiao-Juan Chao, Jin-Feng Wu, Brian Chi-Yan Cheng, Tao Su, Xiu-Qiong Fu, Ting Li, Hui Guo, Anfernee Kai-Wing Tse, Hiu-Yee Kwan, Juan Du, Gui-Xin Chou, Zhi-Ling Yu
Pages: 1543-1548 Published online on: 06 July 2015
Article
Roscovitine has anti-proliferative and pro-apoptotic effects on glioblastoma cell lines: A pilot study
M. Kolodziej, C. Goetz, P. Di Fazio, R. Montalbano, M. Ocker, H. Strik, K. Quint
Pages: 1549-1556 Published online on: 03 July 2015
Article
MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy
Xiangliang Zhang, Huijuan Shi, Shengqv Lin, Mingchen Ba, Shuzhong Cui
Pages: 1557-1564 Published online on: 25 June 2015
Article
Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells
Xiaohui Peng, Yan Zhou, Hua Tian, Gaoxiang Yang, Chunliu Li, Yang Geng, Sai Wu, Wei Wu
Pages: 1565-1572 Published online on: 01 July 2015
Article
miR-133a inhibits cervical cancer growth by targeting EGFR Retraction in /10.3892/or.2021.8103
Xuesong Song, Bo Shi, Kexin Huang, Wenjie Zhang
Pages: 1573-1580 Published online on: 02 July 2015
Article
ERK5 positively regulates cigarette smoke-induced urocystic epithelial-mesenchymal transition in SV‑40 immortalized human urothelial cells
Hao Geng, Li Zhao, Zhaofeng Liang, Zhiqiang Zhang, Dongdong Xie, Liangkuan Bi, Yi Wang, Tao Zhang, Lei Cheng, Dexin Yu, Caiyun Zhong
Pages: 1581-1588 Published online on: 14 July 2015
Article
Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel
David W. Koh, Daniel P. Powell, Steven D. Blake, Joy L. Hoffman, Mandi M. Hopkins, Xiaoxing Feng
Pages: 1589-1598 Published online on: 14 July 2015
Article
Suppression of casein kinase 2 sensitizes tumor cells to antitumor TRAIL therapy by regulating the phosphorylation and localization of p65 in prostate cancer
Xiaokun Gang, Yao Wang, Yingdi Wang, Yu Zhao, Liya Ding, Jingwen Zhao, Lin Sun, Guixia Wang
Pages: 1599-1604 Published online on: 13 July 2015
Article
MicroRNA-20b inhibits the proliferation, migration and invasion of bladder cancer EJ cells via the targeting of cell cycle regulation and Sp-1-mediated MMP-2 expression
Sung Lyea Park, Tae-Min Cho, Se Yeon Won, Jun-Hui Song, Dae‑Hwa Noh, Wun-Jae Kim, Sung-Kwon Moon
Pages: 1605-1612 Published online on: 09 July 2015
Article
Differential effect of EGFR inhibitors on tamoxifen-resistant breast cancer cells
Sangmin Kim, Jeongmin Lee, Soo Jin Oh, Seok Jin Nam, Jeong Eon Lee
Pages: 1613-1619 Published online on: 08 July 2015
Article
