Journal Articles
Review
Thyroid tumor-initiating cells: Increasing evidence and opportunities for anticancer therapy (Review)
Yong-Ju Gao, Bo Li, Xin-Yu Wu, Jing Cui, Jian-Kui Han
Pages: 1035-1042 Published online on: 14 January 2014
Article
High throughput RNAi screening identifies ID1 as a synthetic sick/lethal gene interacting with the common TP53 mutation R175H
Hiroo Imai, Shunsuke Kato, Yasuhiro Sakamoto, Yuichi Kakudo, Hideki Shimodaira, Chikashi Ishioka
Pages: 1043-1050 Published online on: 30 December 2013
Article
Identification of HLA-A2 or HLA-A24-restricted CTL epitopes for potential HSP105-targeted immunotherapy in colorectal cancer
Yu Sawada, Hiroyuki Komori, Yoshiyuki Tsunoda, Manami Shimomura, Mari Takahashi, Hideo Baba, Masaaki Ito, Norio Saito, Hiroyuki Kuwano, Itaru Endo, Yasuharu Nishimura, Tetsuya Nakatsura
Pages: 1051-1058 Published online on: 20 December 2013
Article
Ten-year follow-up of a prospective trial for the targeted therapy of gastric cancer with the human monoclonal antibody PAT-SC1
Frank Hensel, Wolfgang Timmermann, Burkhard H.A. von Rahden, Andreas Rosenwald, Stephanie Brändlein, Bertram Illert
Pages: 1059-1066 Published online on: 20 January 2014
Article
Comprehensive microRNA profiling of prostate cancer cells after ionizing radiation treatment
Chung-Man Leung, Sung-Chou Li, Ting-Wen Chen, Meng-Ru Ho, Ling-Yueh Hu, Wen‑Shan Liu, Tony T. Wu, Ping-Chi Hsu, Hong-Tai Chang, Kuo-Wang Tsai
Pages: 1067-1078 Published online on: 21 January 2014
Article
Analysis of the B-RafV600E mutation in cutaneous melanoma patients with occupational sun exposure
Saverio Candido, Venerando Rapisarda, Andrea Marconi, Grazia Malaponte, Valentina Bevelacqua, Pietro Gangemi, Aurora Scalisi, James A. McCubrey, Roberta Maestro, Demetrios A. Spandidos, Concettina Fenga, Massimo Libra
Pages: 1079-1082 Published online on: 14 January 2014
Article
Preoperative hepatic CT perfusion as an early predictor for the recurrence of esophageal squamous cell carcinoma: Initial clinical results
Takeshi Fujishiro, Kiyohiko Shuto, Koichi Hayano, Asami Satoh, Tsuguaki Kono, Gaku Ohira, Takayuki Tohma, Hisashi Gunji, Kazuo Narushima, Toru Tochigi, Toshiharu Hanaoka, Sayaka Ishii, Noriyuki Yanagawa, Hisahiro Matsubara
Pages: 1083-1088 Published online on: 22 January 2014
Article
A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector
Masami Watanabe, Masakiyo Sakaguchi, Rie Kinoshita, Haruki Kaku, Yuichi Ariyoshi, Hideo Ueki, Ryuta Tanimoto, Shin Ebara, Kazuhiko Ochiai, Junichiro Futami, Shun-Ai Li, Peng Huang, Yasutomo Nasu, Nam-Ho Huh, Hiromi Kumon
Pages: 1089-1095 Published online on: 31 December 2013
Article
MicroRNA-195-5p is a potential diagnostic and therapeutic target for breast cancer
Qifeng Luo, Chuankui Wei, Xiaoyu Li, Jia Li, Lei Chen, Yixiang Huang, Hongming Song, Dengfeng Li, Lin Fang
Pages: 1096-1102 Published online on: 08 January 2014
Article
pp32r1 controls the decay of the RNA-binding protein HuR
Kenji Imamachi, Fumihiro Higashino, Tetsuya Kitamura, Wataru Kakuguchi, Aya Yanagawa-Matsuda, Makoto Ishikawa, Yoshimasa Kitagawa, Yasunori Totsuka, Masanobu Shindoh
Pages: 1103-1108 Published online on: 31 December 2013
Article
Antitumor effect and antiangiogenic potential of the mTOR inhibitor temsirolimus against malignant pleural mesothelioma
Makio Moriya, Tadaaki Yamada, Masaya Tamura, Daisuke Ishikawa, Mir Alireza Hoda, Isao Matsumoto, Walter Klepetko, Makoto Oda, Seiji Yano, Go Watanabe
Pages: 1109-1115 Published online on: 30 December 2013
Article
Expression of fatty acid binding protein 4 is involved in the cell growth of oral squamous cell carcinoma
Doksa Lee, Koichiro Wada, Yoshitaka Taniguchi, Hani Al-Shareef, Tomotake Masuda, Yu Usami, Tomonao Aikawa, Masaya Okura, Yoshinori Kamisaki, Mikihiko Kogo
Pages: 1116-1120 Published online on: 13 January 2014
Article
Glycan profiling of gestational choriocarcinoma using a lectin microarray
Yusuke Kobayashi, Kenta Masuda, Kouji Banno, Nana Kobayashi, Kiyoko Umene, Yuya Nogami, Kosuke Tsuji, Arisa Ueki, Hiroyuki Nomura, Kenji Sato, Eiichiro Tominaga, Takatsune Shimizu, Hideyuki Saya, Daisuke Aoki
Pages: 1121-1126 Published online on: 14 January 2014
Article
The role of CD44+/CD24-/low biomarker for screening, diagnosis and monitoring of breast cancer
Rosa Camerlingo, Giuseppe Andrea Ferraro, Francesco De Francesco, Maurizio Romano, Gianfranco Nicoletti, Maurizio Di Bonito, Massimo Rinaldo, Francesco D'Andrea, Giuseppe Pirozzi
Pages: 1127-1132 Published online on: 23 December 2013
Article
Novel drug discovery system for cancer stem cells in human squamous cell carcinoma of the esophagus
Yoshihiro Kano, Masamitsu Konno, Koichi Kawamoto, Keisuke Tamari, Kazuhiko Hayashi, Takahito Fukusumi, Taroh Satoh, Shinji Tanaka, Kazuhiko Ogawa, Masaki Mori, Yuichiro Doki, Hideshi Ishii
Pages: 1133-1138 Published online on: 30 December 2013
Article
Upregulation of E2F transcription factor 3 is associated with poor prognosis in hepatocellular carcinoma
Xiaoyun Zeng, Fuqiang Yin, Xia Liu, Jianwen Xu, Yang Xu, Jinmei Huang, Yueli Nan, Xiaoqiang Qiu
Pages: 1139-1146 Published online on: 08 January 2014
Article
Human osteosarcoma cells respond to sorafenib chemotherapy by downregulation of the tumor progression factors S100A4, CXCR4 and the oncogene FOS
Ingrid Walter, Birgitt Wolfesberger, Ingrid Miller, Georg Mair, Stefanie Burger, Birgit Gallè, Ralf Steinborn
Pages: 1147-1156 Published online on: 30 December 2013
Article
Upregulation of miR-194 contributes to tumor growth and progression in pancreatic ductal adenocarcinoma
Jing Zhang, Chen-Yan Zhao, Shu-Hui Zhang, Dang-Hui Yu, Ying Chen, Qing-Hua Liu, Min Shi, Can-Rong Ni, Ming-Hua Zhu
Pages: 1157-1164 Published online on: 31 December 2013
Article
Vandetanib-induced inhibition of neuroblastoma cell migration and invasion is associated with downregulation of the SDF-1/CXCR4 axis and matrix metalloproteinase 14
Xionghui Ding, Li Xiang, Ning Wang, Zhanbo Zhao, Xin Jin, Yanhui Sun, Wenjuan Duan, Shiqi Wang, Xianqing Jin
Pages: 1165-1174 Published online on: 31 December 2013
Article
Upregulation of estrogen receptor mediates migration, invasion and proliferation of endometrial carcinoma cells by regulating the PI3K/AKT/mTOR pathway
Xinxin Hou, Meng Zhao, Tong Wang, Guiyu Zhang
Pages: 1175-1182 Published online on: 23 December 2013
Article
Overexpression of AIOLOS inhibits cell proliferation and suppresses apoptosis in Nalm-6 cells
Yong Zhuang, Dong Li, Jinqiu Fu, Qing Shi, Yuanyuan Lu, Xiuli Ju
Pages: 1183-1190 Published online on: 31 December 2013
Article
Overexpression of B7-H1 correlates with malignant cell proliferation in pancreatic cancer
Xiao Song, Junwei Liu, Yi Lu, Hongchuan Jin, Dongsheng Huang
Pages: 1191-1198 Published online on: 31 December 2013
Article
Significance of the vascular endothelial growth factor and the macrophage migration inhibitory factor in the progression of hepatocellular carcinoma
Dong Wang, Liang Luo, Wei Chen, Lian-Zhou Chen, Wen-Tao Zeng, Wen Li, Xiao-Hui Huang
Pages: 1199-1204 Published online on: 23 December 2013
Article
PGC-1α integrates glucose metabolism and angiogenesis in multiple myeloma cells by regulating VEGF and GLUT-4
Dedong Cao, Hao Zhou, Jikai Zhao, Lu Jin, Wen Yu, Han Yan, Yu Hu, Tao Guo
Pages: 1205-1210 Published online on: 09 January 2014
Article
Analysis of SEMA3B methylation and expression patterns in gastric cancer tissue and cell lines
Renpin Chen, Xiaoju Zhuge, Zhiming Huang, Deyi Lu, Xiaohua Ye, Chao Chen, Jieyu Yu, Guangrong Lu
Pages: 1211-1218 Published online on: 09 January 2014
Article
A novel somatic FGFR3 mutation in primary lung cancer
Kazuya Shinmura, Hisami Kato, Shun Matsuura, Yusuke Inoue, Hisaki Igarashi, Kiyoko Nagura, Satoki Nakamura, Kyoko Maruyama, Mari Tajima, Kazuhito Funai, Hiroshi Ogawa, Masayuki Tanahashi, Hiroshi Niwa, Haruhiko Sugimura
Pages: 1219-1224 Published online on: 20 January 2014
Article
Forkhead-box A1 suppresses the progression of endometrial cancer via crosstalk with estrogen receptor α
Jingyun Wang, Wei Bao, Meiting Qiu, Yun Liao, Qi Che, Tingting Yang, Xiaoying He, Haifeng Qiu, Xiaoping Wan
Pages: 1225-1234 Published online on: 20 January 2014
Article
Ovarian cancer stem cell-specific gene expression profiling and targeted drug prescreening
Yuting Huang, Baohui Ju, Jing Tian, Fenghua Liu, Hu Yu, Huiting Xiao, Xiangyu Liu, Wenxin Liu, Zhi Yao, Quan Hao
Pages: 1235-1248 Published online on: 13 January 2014
Article
Silencing of Aurora kinase A by RNA interference inhibits tumor growth in human osteosarcoma cells by inducing apoptosis and G2/M cell cycle arrest
Zhenhuan Jiang, Jiannong Jiang, Huilin Yang, Zhijun Ge, Qiang Wang, Leiyan Zhang, Chenguang Wu, Jinzhi Wang
Pages: 1249-1254 Published online on: 20 January 2014
Article
miR-222 regulates the cell biological behavior of oral squamous cell carcinoma by targeting PUMA
Fangfang Jiang, Wei Zhao, Lijie Zhou, Lin Zhang, Zifeng Liu, Dongsheng Yu
Pages: 1255-1262 Published online on: 20 January 2014
Article
Downregulation of microRNA-26a is associated with metastatic potential and the poor prognosis of osteosarcoma patients
Qi-Chun Song, Zhi-Bin Shi, Yong-Tao Zhang, Le Ji, Kun‑Zheng Wang, Da-Peng Duan, Xiao-Qian Dang
Pages: 1263-1270 Published online on: 21 January 2014
Article
Downregulation of NOB1 suppresses the proliferation and tumor growth of non-small cell lung cancer in vitro and in vivo Retraction in /10.3892/or.2020.7483
Yang Li, Chengyuan Ma, Ming Qian, Zhongmei Wen, Hongyu Jing, Donghua Qian
Pages: 1271-1276 Published online on: 21 January 2014
Article
Expression profiles of 507 proteins from a biotin label-based antibody array in human colorectal cancer
Hisaaki Miyoshi, Asahiro Morishita, Joji Tani, Teppei Sakamoto, Koji Fujita, Akiko Katsura, Miwa Tatsuta, Takako Nomura, Hirohito Yoneyama, Hisakazu Iwama, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 1277-1281 Published online on: 19 December 2013
Article
The heme precursor 5-aminolevulinic acid disrupts the Warburg effect in tumor cells and induces caspase-dependent apoptosis
Yuta Sugiyama, Yuichiro Hagiya, Motowo Nakajima, Masahiro Ishizuka, Tohru Tanaka, Shun-Ichiro Ogura
Pages: 1282-1286 Published online on: 23 December 2013
Article
Intratumoral expression of mature human neutrophil peptide-1 potentiates the therapeutic effect of doxorubicin in a mouse 4T1 breast cancer model
Dan Li, Qing Qin, Xiao-Yi Wang, Hua-Shan Shi, Min Luo, Fu-Chun Guo, Wei Wang, Yong-Sheng Wang
Pages: 1287-1295 Published online on: 30 December 2013
Article
Overexpression of transferrin receptor CD71 and its tumorigenic properties in esophageal squamous cell carcinoma
Kin Tak Chan, Mei Yuk Choi, Kenneth K.Y. Lai, Winnie Tan, Lai Nar Tung, Ho Yu Lam, Daniel K.H. Tong, Nikki P. Lee, Simon Law
Pages: 1296-1304 Published online on: 16 January 2014
Article
Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma
Dai Shimizu, Mitsuro Kanda, Shuji Nomoto, Hisaharu Oya, Hideki Takami, Soki Hibino, Masaya Suenaga, Yoshikuni Inokawa, Mitsuhiro Hishida, Nao Takano, Yoko Nishikawa, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 1305-1313 Published online on: 20 December 2013
Article
siRNA-mediated knockdown of hTDE2 retards cell cycle progression through transcriptional activation of p21
Wei-Hua Ren, Chen-Yi Yang, Xian-Mei Yang, Long Yu
Pages: 1314-1322 Published online on: 14 January 2014
Article
Screening for transcription factors and their regulatory small molecules involved in regulating the functions of CL1-5 cancer cells under the effects of macrophage-conditioned medium
Dongbo Xue, Ming Lu, Bo Gao, Xin Qiao, Yingmei Zhang
Pages: 1323-1333 Published online on: 20 December 2013
Article
Overexpression of cysteine cathepsin L is a marker of invasion and metastasis in ovarian cancer
Wei Zhang, Sumei Wang, Qi Wang, Zhijun Yang, Zhongmian Pan, Li Li
Pages: 1334-1342 Published online on: 08 January 2014
Article
Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway
Yu-Chao Ma, Cui Li, Feng Gao, Yan Xu, Zhi-Bin Jiang, Jian-Xin Liu, Long-Yu Jin
Pages: 1343-1349 Published online on: 19 December 2013
Article
Kaempferol induces cell cycle arrest and apoptosis in renal cell carcinoma through EGFR/p38 signaling
Wenbin Song, Qiang Dang, Defeng Xu, Yule Chen, Guodong Zhu, Kaijie Wu, Jin Zeng, Qingzhi Long, Xinyang Wang, Dalin He, Lei Li
Pages: 1350-1356 Published online on: 07 January 2014
Article
miR-96 promotes tumor proliferation and invasion by targeting RECK in breast cancer
Junfeng Zhang, Xiangjie Kong, Jia Li, Qifeng Luo, Xiaoyu Li, Lei Shen, Lei Chen, Lin Fang
Pages: 1357-1363 Published online on: 19 December 2013
Article
Latexin exhibits tumor suppressor potential in hepatocellular carcinoma
Qing-Feng Ni, Yuan Tian, Liang-Liang Kong, Ye-Ting Lu, Wen-Zhou Ding, Lian-Bao Kong
Pages: 1364-1372 Published online on: 08 January 2014
Article
Ik6 expression provides a new strategy for the therapy of acute lymphoblastic leukemia
Fen Zhou, Yunyun Xu, Yining Qiu, Xiaoyan Wu, Zhiquan Zhang, Runming Jin
Pages: 1373-1379 Published online on: 08 January 2014
Article
TWIST1 and SNAI1 as markers of poor prognosis in human colorectal cancer are associated with the expression of ALDH1 and TGF-β1
Yong Hun Kim, Gwangil Kim, Chang-Il Kwon, Jong Woo Kim, Pil Won Park, Ki-Baik Hahm
Pages: 1380-1388 Published online on: 08 January 2014
Article
RPRD1B promotes tumor growth by accelerating the cell cycle in endometrial cancer
Yuan Wang, Haifeng Qiu, Weixu Hu, Shaoru Li, Jinjin Yu
Pages: 1389-1395 Published online on: 21 January 2014
Article
Association of the p53 codon 72 polymorphism with clinicopathological characteristics of colorectal cancer through mRNA analysis
Ligia Petrolini De Oliveira, Ignacio López, Erika Maria Monteiro Dos Santos, Paula Tucci, Mónica Marín, Fernando Augusto Soares, Benedito Mauro Rossi, Renata De Almeida Coudry
Pages: 1396-1406 Published online on: 20 December 2013
Article
Differential effects of erufosine on proliferation, wound healing and apoptosis in colorectal cancer cell lines
Ferda Kaleağasıoğlu, Martin R. Berger
Pages: 1407-1416 Published online on: 20 December 2013
Article
Aberrant sialylation and fucosylation of intracellular proteins in cervical tissue are critical markers of cervical carcinogenesis
Hyoung Jin Kim, Seung Cheol Kim, Woong Ju, Yun Hwan Kim, Sun Young Yin, Hong-Jin Kim
Pages: 1417-1422 Published online on: 20 December 2013
Article
Protein kinase C-α downregulates estrogen receptor-α by suppressing c-Jun phosphorylation in estrogen receptor-positive breast cancer cells
Sangmin Kim, Jeongmin Lee, Se Kyung Lee, Soo Youn Bae, Jiyoung Kim, Minkuk Kim, Won Ho Kil, Seok Won Kim, Jeong Eon Lee, Seok Jin Nam
Pages: 1423-1428 Published online on: 19 December 2013
Article
miR-186, miR-3651 and miR-494: Potential biomarkers for oral squamous cell carcinoma extracted from whole blood
Jutta Ries, Eleftherios Vairaktaris, Abbas Agaimy, Rita Kintopp, Christoph Baran, Friedrich W. Neukam, Emeka Nkenke
Pages: 1429-1436 Published online on: 20 January 2014
Article
Antitumor effect of adenoviral vector prime protein boost immunity targeting the MUC1 VNTRs
Yuqian Wang, Chenlu Liu, Qiu Xia, Peng Wang, Bo Li, Zhenzhen Lu, Jiaxi Sun, Hui Wu, Bin Yu, Jiaxin Wu, Xianghui Yu, Wei Kong, Haihong Zhang, Xianling Cong
Pages: 1437-1444 Published online on: 30 December 2013
Article
MicroRNA-503 acts as a tumor suppressor in glioblastoma for multiple antitumor effects by targeting IGF-1R
Yingying Zhang, Xiong Chen, Haiwei Lian, Jianmiao Liu, Beiyan Zhou, Song Han, Biwen Peng, Jun Yin, Wanhong Liu, Xiaohua He
Pages: 1445-1452 Published online on: 30 December 2013
Article
Antitumour effect of valproic acid against salivary gland cancer in vitro and in vivo
Hirokazu Nagai, Masako Fujioka-Kobayashi, Go Ohe, Kanae Hara, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, Youji Miyamoto
Pages: 1453-1458 Published online on: 31 December 2013
Article
Post-transcriptional repression of FOXO1 by QKI results in low levels of FOXO1 expression in breast cancer cells
Fang Yu, Liang Jin, Guodong Yang, Lin Ji, Feng Wang, Zifan Lu
Pages: 1459-1465 Published online on: 31 December 2013
Article
The role of plasma cell-free DNA detection in predicting preoperative chemoradiotherapy response in rectal cancer patients
W. Sun, Y. Sun, M. Zhu, Z. Wang, H. Zhang, Y. Xin, G. Jiang, X. Guo, Z. Zhang, Y. Liu
Pages: 1466-1472 Published online on: 30 December 2013
Article
miR-511 induces the apoptosis of radioresistant lung adenocarcinoma cells by triggering BAX
Han-Han Zhang, Min Pang, Wei Dong, Jia-Xuan Xin, You-Jie Li, Zi-Cheng Zhang, Liang Yu, Ping-Yu Wang, Bao-Sheng Li, Shu-Yang Xie
Pages: 1473-1479 Published online on: 09 January 2014
Article
Nicotine promotes cell proliferation and induces resistance to cisplatin by α7 nicotinic acetylcholine receptor‑mediated activation in Raw264.7 and El4 cells
Yan Yan Wang, Yao Liu, Xiao Yan Ni, Zhen Huan Bai, Qiong Yun Chen, Ye Zhang, Feng Guang Gao
Pages: 1480-1488 Published online on: 31 December 2013
Article