Journal Articles
Review
LIM homeobox transcription factors, a novel subfamily which plays an important role in cancer (Review)
Xi Wang, Chao He, Xiaotong Hu
Pages: 1975-1985 Published online on: 27 March 2014
Article
Clinical and biological impact of cyclin-dependent kinase subunit 2 in esophageal squamous cell carcinoma
Yoshiaki Kita, Yuka Nishizono, Hiroshi Okumura, Yasuto Uchikado, Ken Sasaki, Masataka Matsumoto, Tetsuro Setoyama, Kiyonori Tanoue, Itaru Omoto, Shinichiro Mori, Tetsuhiro Owaki, Sumiya Ishigami, Hiroshi Nakagawa, Fumiaki Tanaka, Koshi Mimori, Masaki Mori, Shoji Natsugoe
Pages: 1986-1992 Published online on: 05 March 2014
Article
Upregulation of long non-coding RNA urothelial carcinoma associated 1 by CCAAT/enhancer binding protein α contributes to bladder cancer cell growth and reduced apoptosis
Mei Xue, Xu Li, Wenjing Wu, Shuwan Zhang, Shouzhen Wu, Zhengkun Li, Wei Chen
Pages: 1993-2000 Published online on: 19 March 2014
Article
The BRCA2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells
Yosuke Nakagawa, Atsuhisa Kajihara, Akihisa Takahashi, Natsuko Kondo, Eiichiro Mori, Tadaaki Kirita, Takeo Ohnishi
Pages: 2001-2006 Published online on: 11 March 2014
Article
Non-invasive monitoring of anticancer effects of cisplatin on lung cancer in an orthotopic SCID mouse model using [18F] FDG PET-CT
Mohamed Mokhtar, Kazuya Kondo, Hiromitsu Takizawa, Tamaki Ohtani, Hideki Otsuka, Hitoshi Kubo, Koichiro Kajiura, Yasushi Nakagawa, Yukikiyo Kawakami, Mitsuteru Yoshida, Haruhiko Fujino, Shoji Sakiyama, Akira Tangoku
Pages: 2007-2014 Published online on: 05 March 2014
Article
Nilotinib combined with interleukin-2 mediates antitumor and immunological effects in a B16 melanoma model
K. Geisler, A. Reischer, I. Kroeger, B. Jacobs, K. Meinhardt, R. Bauer, B. Ryffel, A. Mackensen, E. Ullrich
Pages: 2015-2020 Published online on: 10 March 2014
Article
miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
Fei Guo, David Cogdell, Limei Hu, Da Yang, Anil K. Sood, Fengxia Xue, Wei Zhang
Pages: 2021-2028 Published online on: 21 March 2014
Article
MicroRNA expression profiles in supraglottic carcinoma
Tianhong Zhang, Guojun Han, Yansong Wang, Kewa Chen, Yanan Sun
Pages: 2029-2034 Published online on: 27 March 2014
Article
Overexpression of microRNA-143 inhibits growth and induces apoptosis in human leukemia cells
Jian-Zhen Shen, Yuan-Yuan Zhang, Hai-Ying Fu, Dan-Sen Wu, Hua-Rong Zhou
Pages: 2035-2042 Published online on: 11 March 2014
Article
Low expression of GABARAPL1 is associated with a poor outcome for patients with hepatocellular carcinoma
Chao Liu, Yan Xia, Wei Jiang, Yinkun Liu, Long Yu
Pages: 2043-2048 Published online on: 19 March 2014
Article
Eotaxin-1 promotes prostate cancer cell invasion via activation of the CCR3-ERK pathway and upregulation of MMP-3 expression
Feng Zhu, Pei Liu, Jun Li, Yan Zhang
Pages: 2049-2054 Published online on: 05 March 2014
Article
MicroRNA-100 regulates SW620 colorectal cancer cell proliferation and invasion by targeting RAP1B
Hui Peng, Jun Luo, Hu Hao, Jun Hu, Shang-Kui Xie, Donglin Ren, Benqiang Rao
Pages: 2055-2062 Published online on: 11 March 2014
Article
Thymoquinone induces G2/M arrest, inactivates PI3K/Akt and nuclear factor-κB pathways in human cholangiocarcinomas both in vitro and in vivo
Dongsheng Xu, Yong Ma, Baolei Zhao, Shuai Li, Yu Zhang, Shangha Pan, Yaohua Wu, Jizhou Wang, Dawei Wang, Huayang Pan, Lianxin Liu, Hongchi Jiang
Pages: 2063-2070 Published online on: 05 March 2014
Article
MCM7 serves as a prognostic marker in diffuse-type gastric adenocarcinoma and siRNA-mediated knockdown suppresses its oncogenic function
Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Alfred S.L. Cheng, Jun Yu, Kafai To
Pages: 2071-2078 Published online on: 19 March 2014
Article
Editing genomic DNA in cancer cells with high genetic variance: Benefit or risk?
Lin Wang, Yixiang Wang, Chuanbin Guo
Pages: 2079-2084 Published online on: 06 March 2014
Article
Suppressive role of miR-502-5p in breast cancer via downregulation of TRAF2
Li-Li Sun, Jian Wang, Zhi-Juan Zhao, Ning Liu, Ai-Lian Wang, Hua-Yan Ren, Fan Yang, Ke-Xin Diao, Wei-Neng Fu, En-Hua Wan, Xiao-Yi Mi
Pages: 2085-2092 Published online on: 21 March 2014
Article
A targeting peptide improves adenovirus-mediated transduction of a glioblastoma cell line
Dongyang Wang, Wenbo Li, Hang Zhang, Qinwen Mao, Haibin Xia
Pages: 2093-2098 Published online on: 06 March 2014
Article
Prostaglandin E2 receptor EP2 mediates Snail expression in hepatocellular carcinoma cells
Shan-Yu Cheng, Hai Zhang, Min Zhang, Shu-Kai Xia, Xiao‑Ming Bai, Li Zhang, Juan Ma, Rong Rong, Yi-Pin Wang, Ming-Zhan Du, Jie Wang, Meng Chen, Feng Shi, Qin-Yi Yang, Jing Leng
Pages: 2099-2106 Published online on: 11 March 2014
Article
Thioridazine, an antipsychotic drug, elicits potent antitumor effects in gastric cancer
Jiasheng Mu, Haineng Xu, Yu Yang, Weidan Huang, Jing Xiao, Maolan Li, Zhujun Tan, Qichen Ding, Lin Zhang, Jianhua Lu, Xiangsong Wu, Yingbin Liu
Pages: 2107-2114 Published online on: 06 March 2014
Article
Cetuximab-mediated ADCC activity is correlated with the cell surface expression level of EGFR but not with the KRAS/BRAF mutational status in colorectal cancer
Yuki Seo, Yoshiyuki Ishii, Hiroki Ochiai, Kazumasa Fukuda, Shingo Akimoto, Tetsu Hayashida, Koji Okabayashi, Masashi Tsuruta, Hirotoshi Hasegawa, Yuko Kitagawa
Pages: 2115-2122 Published online on: 11 March 2014
Article
IL-1β-stimulated urokinase plasminogen activator expression through NF-κB in gastric cancer after HGF treatment
Kyung Hee Lee, Eun Young Choi, Sung Ae Koh, Min Kyoung Kim, Byung Ik Jang, Sang Woon Kim, Jae-Ryong Kim
Pages: 2123-2130 Published online on: 12 March 2014
Article
β-elemene reverses the drug resistance of lung cancer A549/DDP cells via the mitochondrial apoptosis pathway
Cheng-Cai Yao, Yuan-Rong Tu, Jie Jiang, Sheng-Fang Ye, Hao-Xin Du, Yi Zhang
Pages: 2131-2138 Published online on: 12 March 2014
Article
Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer
Nam Hee Kim, Hye Youn Sung, Eun Nam Choi, Dahyun Lyu, Hyuck Jae Choi, Woong Ju, Jung-Hyuck Ahn
Pages: 2139-2146 Published online on: 24 March 2014
Article
MicroRNA expression profiles in human breast cancer cells after multifraction and single-dose radiation treatment
Chung-Man Leung, Ting-Wen Chen, Sung-Chou Li, Meng-Ru Ho, Ling-Yueh Hu, Wen‑Shan Liu, Tony T. Wu, Ping-Chi Hsu, Hong-Tai Chang, Kuo-Wang Tsai
Pages: 2147-2156 Published online on: 13 March 2014
Article
Coexpression of ANXA2, SOD2 and HOXA13 predicts poor prognosis of esophageal squamous cell carcinoma
Ruo-Lan Ma, Lu-Yan Shen, Ke-Neng Chen
Pages: 2157-2164 Published online on: 12 March 2014
Article
Proteomic and functional analyses demonstrate the involvement of oxidative stress in the anticancer activities of oridonin in HepG2 cells
Hui Wang, Yan Ye, Zhi-Ling Yu
Pages: 2165-2172 Published online on: 12 March 2014
Article
STAT3 inhibitor WP1066 attenuates miRNA-21 to suppress human oral squamous cell carcinoma growth in vitro and in vivo
Xuan Zhou, Yu Ren, Aiqin Liu, Lei Han, Kailiang Zhang, Shasha Li, Peng Li, Ping Li, Chunsheng Kang, Xudong Wang, Lun Zhang
Pages: 2173-2180 Published online on: 27 March 2014
Article
Triptolide-induced in vitro and in vivo cytotoxicity in human breast cancer stem cells and primary breast cancer cells
Junjie Li, Ruilei Liu, Ye Yang, Yong Huang, Xi Li, Ruiming Liu, Xiaoyan Shen
Pages: 2181-2186 Published online on: 27 March 2014
Article
Upregulation of the splice variant MUC4/Y in the pancreatic cancer cell line MIA PaCa-2 potentiates proliferation and suppresses apoptosis: New insight into the presence of the transcript variant of MUC4
Kunling Xie, Xiaofei Zhi, Jie Tang, Yi Zhu, Jingjing Zhang, Zheng Li, Jinqiu Tao, Zekuan Xu
Pages: 2187-2194 Published online on: 27 March 2014
Article
Dosimetric comparison of left-sided whole breast irradiation with 3D-CRT, IP-IMRT and hybrid IMRT
Xiaoxue Xie, Shuyu Ouyang, Hui Wang, Wenjuan Yang, Hekun Jin, Bingqiang Hu, Liangfang Shen
Pages: 2195-2205 Published online on: 05 March 2014
Article
Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker
Jinbang Li, Pinggui Gong, Xiaoming Lyu, Kaitai Yao, Xin Li, Hong Peng
Pages: 2206-2212 Published online on: 05 March 2014
Article
Ki-67 as an independent prognostic factor in an unselected cohort of patients with ovarian cancer: Results of an explorative, retrospective study
Marco Johannes Battista, Nina Mantai, Isabel Sicking, Cristina Cotarelo, Veronika Weyer, Antje Lebrecht, Christine Solbach, Marcus Schmidt
Pages: 2213-2219 Published online on: 11 March 2014
Article
Synergistic effect of nanosecond pulsed electric field combined with low-dose of pingyangmycin on salivary adenoid cystic carcinoma
Wei Qi, Jinsong Guo, Shan Wu, Bo Su, Lei Zhang, Jie Pan, Jue Zhang
Pages: 2220-2228 Published online on: 06 March 2014
Article
Evaluation of premature senescence and senescence biomarkers in carcinoma cells and xenograft mice exposed to single or fractionated irradiation
Bong Cho Kim, Hee Jung Yoo, Hyung Chul Lee, Kyoung-Ah Kang, Seung Hee Jung, Hae-June Lee, Minyoung Lee, Seungwoo Park, Young-Hoon Ji, Yun-Sil Lee, Young-Gyu Ko, Jae-Seon Lee
Pages: 2229-2235 Published online on: 07 March 2014
Article
PTEN mutation, loss of heterozygosity, promoter methylation and expression in colorectal carcinoma: Two hits on the gene?
Maja Hühns, Tareq Salem, Björn Schneider, Mathias Krohn, Michael Linnebacher, Friedrich Prall
Pages: 2236-2244 Published online on: 19 March 2014
Article
L-securinine induces apoptosis in the human promyelocytic leukemia cell line HL-60 and influences the expression of genes involved in the PI3K/AKT/mTOR signaling pathway
Shuwen Han, Gang Zhang, Maidong Li, Dongyun Chen, Ying Wang, Wencai Ye, Zhaoning Ji
Pages: 2245-2251 Published online on: 20 March 2014
Article
Antitumor effect of a selective COX-2 inhibitor, celecoxib, may be attributed to angiogenesis inhibition through modulating the PTEN/PI3K/Akt/HIF-1 pathway in an H22 murine hepatocarcinoma model
Wenwen Sui, Yueying Zhang, Zhaopeng Wang, Zhaoxia Wang, Qing Jia, Licun Wu, Weidong Zhang
Pages: 2252-2260 Published online on: 19 March 2014
Article
MicroRNA-127-3p promotes glioblastoma cell migration and invasion by targeting the tumor-suppressor gene SEPT7
Huawei Jiang, Dasong Hua, Jing Zhang, Qing Lan, Qiang Huang, Jae-Geun Yoon, Xu Han, Lisha Li, Gregory Foltz, Shu Zheng, Biaoyang Lin
Pages: 2261-2269 Published online on: 05 March 2014
Article
Tumor suppressor DLC-1 induces apoptosis and inhibits the growth and invasion of colon cancer cells through the Wnt/β-catenin signaling pathway
Chunyi Wang, Jialin Wang, Hong Liu, Zhongxue Fu
Pages: 2270-2278 Published online on: 05 March 2014
Article
N-myc downstream regulated gene 1 acts as a tumor suppressor in ovarian cancer
Bei Wang, Jianli Li, Zhanying Ye, Zhe Li, Xiaohua Wu
Pages: 2279-2285 Published online on: 11 March 2014
Article
Induction of apoptosis by diphenyldifluoroketone in osteogenic sarcoma cells is associated with activation of caspases
Seok-Jin Yang, Seul Ah Lee, Min-Gyeong Park, Jae-Sung Kim, Sun-Kyoung Yu, Chun Sung Kim, Jin-Soo Kim, Su-Gwan Kim, Ji-Su Oh, Heung-Joong Kim, Hong Sung Chun, Yong Hwan Kim, Do Kyung Kim
Pages: 2286-2292 Published online on: 06 March 2014
Article
Synergistic antitumor activity of resveratrol and miR-200c in human lung cancer
Tao Bai, Dao-Song Dong, Ling Pei
Pages: 2293-2297 Published online on: 14 March 2014
Article
Functional expression of TLR9 in esophageal cancer
Yanli Zhang, Qiuyan Wang, Ailing Ma, Yunhong Li, Rui Li, Yin Wang
Pages: 2298-2304 Published online on: 19 March 2014
Article
Arsenic hexoxide enhances TNF-α-induced anticancer effects by inhibiting NF-κB activity at a safe dose in MCF-7 human breast cancer cells
Min Jeong Kim, Ji Hyun Jung, Won Sup Lee, Jeong Won Yun, Jing Nan Lu, Sang Mi Yi, Hye Jung Kim, Seong-Hwan Chang, Gon-Sup Kim, Soon Chan Hong, Woo Song Ha
Pages: 2305-2311 Published online on: 12 March 2014
Article
SPARC expression is negatively correlated with clinicopathological factors of gastric cancer and inhibits malignancy of gastric cancer cells
Junling Zhang, Pengyuan Wang, Jing Zhu, Wei Wang, Jie Yin, Chi Zhang, Ziyi Chen, Lie Sun, Yuanlian Wan, Xin Wang, Guowei Chen, Yucun Liu
Pages: 2312-2320 Published online on: 27 March 2014
Article
Autophagy promotes the survival and development of tumors by participating in the formation of vasculogenic mimicry
Yun-Peng Ding, Xiao-Dong Yang, Yong Wu, Chun-Gen Xing
Pages: 2321-2327 Published online on: 12 March 2014
Article
Vigilin is overexpressed in hepatocellular carcinoma and is required for HCC cell proliferation and tumor growth
Wen Li Yang, Ling Wei, Wen Qing Huang, Ran Li, Wen Yan Shen, Jian Yu Liu, Jian Ming Xu, Bo Li, Yang Qin
Pages: 2328-2334 Published online on: 24 March 2014
Article
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells
Jing Kuang, Ya-Lan Wang, Ming Xiao, Yi Tang, Wen‑Wen Chen, Guang-Lin Song, Xi Yang, Ming Li
Pages: 2335-2343 Published online on: 20 March 2014
Article
Knockdown of S100P by lentiviral-mediated RNAi promotes apoptosis and suppresses the colony-formation ability of gastric cancer cells
Qi Zhang, Haolin Hu, Xin Shi, Wenhao Tang
Pages: 2344-2350 Published online on: 21 March 2014
Article
FRZB knockdown upregulates β-catenin activity and enhances cell aggressiveness in gastric cancer
Shuai Qin, Zhuo Zhang, Jianfang Li, Lu Zang
Pages: 2351-2357 Published online on: 24 March 2014
Article
Breast cancer cells are arrested at different phases of the cell cycle following the re-expression of ARHI
Xiaoxiao Zuo, Yan Qin, Xiaojin Zhang, Qian Ning, Shan Shao, Minna Luo, Na Yuan, Shangke Huang, Xinhan Zhao
Pages: 2358-2364 Published online on: 21 March 2014
Article
The role of autophagy induced by pemetrexed in lung adenocarcinoma cells
Ji-Hye Park, Young-Rae Lee, Hong-Seob So, Kang-Kyoo Lee, Sam‑Youn Lee, Sun-Rock Moon, Hyang-Jeong Jo, Seoul Lee, Kyuyong Jeong, Kang-Beom Kwon, Sei-Hoon Yang
Pages: 2365-2370 Published online on: 10 March 2014
Article
Vitamin B6 activates p53 and elevates p21 gene expression in cancer cells and the mouse colon
Peipei Zhang, Sofya Suidasari, Tomomi Hasegawa, Noriyuki Yanaka, Norihisa Kato
Pages: 2371-2376 Published online on: 11 March 2014
Article
Isoquercitrin inhibits the progression of liver cancer in vivo and in vitro via the MAPK signalling pathway Retraction in /10.3892/or.2023.8510
Guihong Huang, Bo Tang, Kun Tang, Xiaomin Dong, Jungang Deng, Luqin Liao, Zengzhen Liao, Hua Yang, Songqing He
Pages: 2377-2384 Published online on: 20 March 2014
Article
Expression of the monocyte chemotactic protein-1-induced protein 1 decreases human neuroblastoma cell survival
Anna Skalniak, Elżbieta Boratyn, Sylwia D. Tyrkalska, Irena Horwacik, Małgorzata Durbas, Maria Łastowska, Jolanta Jura, Hanna Rokita
Pages: 2385-2392 Published online on: 11 March 2014
Article
Transphosphorylation of EGFR at Y845 plays an important role in its autophosphorylation and kinase activity
Hui Song, Lei Huang, Ming Zhang, Xiuwei Wang, Shuang Song, Lin Yang
Pages: 2393-2398 Published online on: 21 March 2014
Article
Oleanolic acid enhances the radiosensitivity of tumor cells under mimetic hypoxia through the reduction in intracellular GSH content and HIF-1α expression
Rongxin Qi, Wenwen Jin, Juan Wang, Qiyi Yi, Maohu Yu, Shiguo Xu, Wensen Jin
Pages: 2399-2406 Published online on: 06 March 2014
Article
Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer
Roberto Berretta, Tito Silvio Patrelli, Costanza Migliavacca, Martino Rolla, Laura Franchi, Michela Monica, Alberto Bacchi Modena, Salvatore Gizzo
Pages: 2407-2412 Published online on: 21 March 2014
Article
Anti-apoptotic effect of caspase inhibitors on H2O2-treated HeLa cells through early suppression of its oxidative stress
Woo Hyun Park
Pages: 2413-2421 Published online on: 12 March 2014
Article
Arecoline inhibits epithelial cell viability by upregulating the apoptosis pathway: Implication for oral submucous fibrosis
Ming Li, Feng Gao, Zhong-Su Zhou, Hui-Ming Zhang, Rui Zhang, Ying-Fang Wu, Ming-Hai Bai, Ji-Jia Li, Shi-Rong Lin, Jie-Ying Peng
Pages: 2422-2428 Published online on: 14 March 2014
Article
Sequential treatment of HPV E6 and E7-expressing TC-1 cells with bortezomib and celecoxib promotes apoptosis through p-p38 MAPK-mediated downregulation of cyclin D1 and CDK2
Jee-Eun Kim, Ji-In Lee, Dong-Hoon Jin, Wang Jae Lee, Ga Bin Park, Seonghan Kim, Yeong Seok Kim, T.-C. Wu, Dae Young Hur, Daejin Kim
Pages: 2429-2437 Published online on: 12 March 2014
Article
Methylation and decreased expression of SHP-1 are related to disease progression in chronic myelogenous leukemia
Yinghua Li, Lin Yang, Yuxia Pan, Jingci Yang, Yintao Shang, Jianmin Luo
Pages: 2438-2446 Published online on: 19 March 2014
Article
Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by suppressing MMP‑2 and MMP‑9 via downregulation of NF-κB signaling pathway
Ki Rim Lee, Jong Seok Lee, Young Rae Kim, In Gyu Song, Eock Kee Hong
Pages: 2447-2453 Published online on: 21 March 2014
Article
