Journal Articles
Review
Targeting the NF-E2-related factor 2 pathway: A novel strategy for glioblastoma (Review)
Jianhong Zhu, Handong Wang, Youwu Fan, Yixing Lin, Li Zhang, Xiangjun Ji, Mengliang Zhou
Pages: 443-450 Published online on: 12 June 2014
Review
Clinical evidence of the relationship between aspirin and breast cancer risk (Review)
Nadia J. Jacobo-Herrera, Carlos Pérez-Plasencia, Elizabeth Camacho‑Zavala, Gabriela Figueroa González, Eduardo López Urrutia, Verónica García‑Castillo, Alejandro Zentella-Dehesa
Pages: 451-451 Published online on: 13 June 2014
Article
hBD-2 is downregulated in oral carcinoma cells by DNA hypermethylation, and increased expression of hBD-2 by DNA demethylation and gene transfection inhibits cell proliferation and invasion
Yoshitaka Kamino, Yoshihito Kurashige, Osamu Uehara, Jun Sato, Michiko Nishimura, Koki Yoshida, Toshiya Arakawa, Hiroki Nagayasu, Masato Saitoh, Yoshihiro Abiko
Pages: 462-468 Published online on: 12 June 2014
Article
Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug
Lauren Amable, Jason Fain, Elaine Gavin, Eddie Reed
Pages: 469-474 Published online on: 12 June 2014
Article
Combined effects of asbestos and cigarette smoke on the development of lung adenocarcinoma: Different carcinogens may cause different genomic changes
Kentaro Inamura, Hironori Ninomiya, Kimie Nomura, Eiju Tsuchiya, Yukitoshi Satoh, Sakae Okumura, Ken Nakagawa, Ayako Takata, Norihiko Kohyama, Yuichi Ishikawa
Pages: 475-482 Published online on: 13 June 2014
Article
Genomic characterization of ependymomas reveals 6q loss as the most common aberration
Thale Kristin Olsen, Ludmila Gorunova, Torstein R. Meling, Francesca Micci, David Scheie, Bernt Due-Tønnessen, Sverre Heim, Petter Brandal
Pages: 483-490 Published online on: 16 June 2014
Article
Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment
Magdalena Milczarek, Beata Filip-Psurska, Wiesław Świętnicki, Andrzej Kutner, Joanna Wietrzyk
Pages: 491-504 Published online on: 11 June 2014
Article
Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity
Rafael Guerrero-Preston, Tal Hadar, Kimberly Laskie Ostrow, Ethan Soudry, Miguel Echenique, Carmen Ili-Gangas, Gabriela Pérez, Jimena Perez, Priscilla Brebi-Mieville, José Deschamps, Luisa Morales, Manuel Bayona, David Sidransky, Jaime Matta
Pages: 505-512 Published online on: 13 June 2014
Article
PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin
Meng-Yao Wu, Xin Xie, Ze-Kuan Xu, Li Xie, Zheng Chen, Liu‑Mei Shou, Fei-Ran Gong, Yu-Feng Xie, Wei Li, Min Tao
Pages: 513-522 Published online on: 13 June 2014
Article
Involvement of macrophage migration inhibitory factor and its receptor (CD74) in human breast cancer
Vincent Richard, Nadège Kindt, Christine Decaestecker, Hans‑Joachim Gabius, Guy Laurent, Jean-Christophe Noël, Sven Saussez
Pages: 523-529 Published online on: 16 June 2014
Article
Prognostic factors in Epstein-Barr virus-associated stage I-III gastric carcinoma: Implications for a unique type of carcinogenesis
Shih-Chiang Huang, Kwai-Fong Ng, Kuang-Hua Chen, Jun‑Te Hsu, Keng-Hao Liu, Ta-Sen Yeh, Tse-Ching Chen
Pages: 530-538 Published online on: 05 June 2014
Article
Fusion of HepG2 cells with mesenchymal stem cells increases cancer‑associated and malignant properties: An in vivo metastasis model
Hong Li, Zhenqing Feng, Tom C. Tsang, Tian Tang, Xiaoqin Jia, Xianghui He, Michael E. Pennington, Michael S. Badowski, Anna K.M. Liu, Deyu Chen, David T. Harris, Jesse Martinez, Linda C. Meade-Tollin
Pages: 539-547 Published online on: 13 June 2014
Article
A single nucleotide polymorphism in fibronectin 1 determines tumor shape in colorectal cancer
Hiroyuki Kida, Yuki Takano, Ken Yamamoto, Masaki Mori, Katsuhiko Yanaga, Jun-Ichi Tanaka, Shin-Ei Kudo, Koshi Mimori
Pages: 548-552 Published online on: 12 June 2014
Article
The PI3K/mTOR dual inhibitor NVP-BEZ235 reduces the growth of ovarian clear cell carcinoma
Tetsuro Oishi, Hiroaki Itamochi, Akiko Kudoh, Michiko Nonaka, Misaki Kato, Mayumi Nishimura, Nao Oumi, Seiya Sato, Jun Naniwa, Shinya Sato, Muneaki Shimada, Junzo Kigawa, Tasuku Harada
Pages: 553-558 Published online on: 13 June 2014
Article
Blocking PI3K/Akt signaling attenuates metastasis of nasopharyngeal carcinoma cells through induction of mesenchymal-epithelial reverting transition
Hanguo Jiang, Mei Gao, Zhihua Shen, Botao Luo, Rujia Li, Xiaofan Jiang, Ranran Ding, Yanping Ha, Zhenliang Wang, Wei Jie
Pages: 559-566 Published online on: 29 May 2014
Article
Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways
Jia Liu, Lanhong Zheng, Jiateng Zhong, Ning Wu, Ge Liu, Xiukun Lin
Pages: 567-572 Published online on: 06 June 2014
Article
Plasmid-based Stat3-specific siRNA and GRIM-19 inhibit the growth of thyroid cancer cells in vitro and in vivo
Gui-Min Wang, Zhong-Xi Ren, Pei-Song Wang, Chang Su, Wen-Xin Zhang, Zeng-Guang Liu, Ling Zhang, Xue-Jian Zhao, Guang Chen
Pages: 573-580 Published online on: 05 June 2014
Article
Reduced BMP6 expression by DNA methylation contributes to EMT and drug resistance in breast cancer cells
Geng Liu, Yuan-Jie Liu, Wen-Jing Lian, Zhi-Wei Zhao, Tao Yi, Hong-Ying Zhou
Pages: 581-588 Published online on: 29 May 2014
Article
miR-5000-3p, miR-5009-3P and miR-552: Potential microRNA biomarkers of side population cells in colon cancer
Zhong-Sheng Xia, Lin Wang, Tao Yu, Wa Zhong, Guo-Da Lian, Di Wu, Hui-Min Zhou, Guang-Cheng Chen
Pages: 589-596 Published online on: 04 June 2014
Article
Quinazoline analog HMJ-30 inhibits angiogenesis: Involvement of endothelial cell apoptosis through ROS-JNK-mediated death receptor 5 signaling
Chi-Cheng Lu, Hao-Ping Chen, Jo-Hua Chiang, Yi-An Jin, Sheng-Chu Kuo, Tian-Shung Wu, Mann-Jen Hour, Jai-Sing Yang, Yu-Jen Chiu
Pages: 597-606 Published online on: 12 June 2014
Article
Overexpression of Tiam1 is associated with malignant phenotypes of nasopharyngeal carcinoma
Yi Ding, Bin Chen, Jing Huang, Wenli Zhang, Hongjun Yang, Yongjian Deng, Jie Lin, Shuang Wang, Xiangmei Zhang
Pages: 607-618 Published online on: 06 June 2014
Article
Involvement of Drp1 in hypoxia-induced migration of human glioblastoma U251 cells
Yu-Ying Wan, Jian-Feng Zhang, Zhang-Jian Yang, Li-Ping Jiang, Yong‑Fang Wei, Qi-Nan Lai, Jian-Bin Wang, Hong-Bo Xin, Xiao-Jian Han
Pages: 619-626 Published online on: 05 June 2014
Article
A771726, an anti-inflammatory drug, exerts an anticancer effect and reverses tamoxifen resistance in endocrine‑resistant breast cancer cells
Ou Huang, Zuoquan Xie, Weili Zhang, Ying Lou, Yan Mao, Hongchun Liu, Min Jiang, Kunwei Shen
Pages: 627-634 Published online on: 12 June 2014
Article
Effect of brachytherapy on NF-κB and VEGF in gastric carcinoma xenografts
Wan-Fu Zhang, Wen-Di Jin, Bo Li, Ming-Chun Wang, Xiao-Gang Li, Wen-Yuan Mao, Kai-Yuan Luo
Pages: 635-640 Published online on: 12 June 2014
Article
Cancer stem cell differentiation: TGFβ1 and versican may trigger molecules for the organization of tumor spheroids
G. Oktem, O. Sercan, U. Guven, R. Uslu, A. Uysal, G. Goksel, S. Ayla, A. Bilir
Pages: 641-649 Published online on: 12 June 2014
Article
Ad-endostatin treatment combined with low-dose irradiation in a murine lung cancer model
Xiao-Peng Li, Hai-Long Zhang, Hui-Juan Wang, Yong-Xia Li, Meng Li, Lian Lu, Yang Wan, Bai-Ling Zhou, Yan Liu, Ying Pan, Xiao-Zhe Wu, Ying-Zi Fan, Chao-Heng Yu, Yu-Quan Wei, Hua-Shan Shi
Pages: 650-658 Published online on: 12 June 2014
Article
The dineolignan from Saururus chinensis, manassantin B, inhibits tumor-induced angiogenesis via downregulation of matrix metalloproteinases 9 in human endothelial cells
Zhaojie Liu, Hong Lu, Rong Liu, Bin Chen, Shan Wang, Junchao Ma, Jianjiang Fu
Pages: 659-667 Published online on: 11 June 2014
Article
Imatinib-associated matrix metalloproteinase suppression in p16-positive squamous cell carcinoma compared to HPV-negative HNSCC cells in vitro
Claudia Umbreit, Christoph Aderhold, Anne Faber, Alexander Sauter, Ralf-Dieter Hofheinz, Jens Stern-Straeter, Karl Hoermann, Johannes David Schultz
Pages: 668-676 Published online on: 30 May 2014
Article
CD166 plays a pro-carcinogenic role in liver cancer cells via inhibition of FOXO proteins through AKT
Wenjun Yu, Jiayi Wang, Lifang Ma, Xun Tang, Yongxia Qiao, Quihui Pan, Yongchun Yu, Fenyong Sun
Pages: 677-683 Published online on: 30 May 2014
Article
Establishment of NOD/SCID mouse model of central nervous system leukemia
Dongfang Li, Pinggan Li, Zhanwen He, Zhe Meng, Xiangyang Luo, Jianpei Fang
Pages: 684-690 Published online on: 12 June 2014
Article
Using [18F]FBAU for imaging brain tumor progression in an F98/tk-luc glioma-bearing rat model
Yi-Chun Chien, John Chun-Hao Chen, Wei-Chan Lin, Hueisch-Jy Ding, Hsin-Ell Wang, Chih-Hao K. Kao, Jeng-Jong Hwang
Pages: 691-699 Published online on: 12 June 2014
Article
Characterization of EGFR family gene aberrations in cholangiocarcinoma
Xiaoqing Yang, Weishan Wang, Chunni Wang, Lin Wang, Muyi Yang, Mei Qi, Hong Su, Xiubin Sun, Zhiyan Liu, Juan Zhang, Xiaomin Qin, Bo Han
Pages: 700-708 Published online on: 13 June 2014
Article
In vivo assessment of the vascular disrupting effect of M410 by DCE-MRI biomarker in a rabbit model of liver tumor
Rui-Meng Yang, Yong Zou, Dan-Ping Huang, Sheng‑Sheng Lai, Xiang‑Dong Xu, Xin‑Hua Wei, Han-Zheng Chang, Tong‑Kun Huang, Li Wang, Wen-Jie Tang, Xin-Qing Jiang
Pages: 709-715 Published online on: 04 June 2014
Article
Norcantharidin enhances ABT-263-mediated anticancer activity in neuroblastoma cells by upregulation of Noxa
Xiaohui Wang, Zhimin Gu, Gongquan Li, Shufeng Zhang, Zhenjie Cao, Zhanfeng Yang, Guangzhi Liu
Pages: 716-722 Published online on: 30 May 2014
Article
Hypoxia-targeted triple suicide gene therapy radiosensitizes human colorectal cancer cells
Hung Tsung Hsiao, Ligang Xing, Xuelong Deng, Xiaorong Sun, C. Clifton Ling, Gloria C. Li
Pages: 723-729 Published online on: 06 June 2014
Article
Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma
Pauline J. van der Watt, Widaad Zemanay, Dhirendra Govender, Denver T. Hendricks, M. I. Parker, Virna D. Leaner
Pages: 730-738 Published online on: 04 June 2014
Article
Gene expression profiling of HL-60 cells following knockdown of nucleostemin using DNA microarrays
Xiaoli Sun, Yu Jia, Yuanyu Wei, Shuai Liu, Baohong Yue
Pages: 739-747 Published online on: 06 June 2014
Article
Overexpression of flotillin-1 is involved in proliferation and recurrence of bladder transitional cell carcinoma
Yawei Guan, Haiyan Song, Guohui Zhang, Xing Ai
Pages: 748-754 Published online on: 29 May 2014
Article
Co-expression of CD133, CD44v6 and human tissue factor is associated with metastasis and poor prognosis in pancreatic carcinoma
Kai Chen, Zhonghu Li, Peng Jiang, Xi Zhang, Yujun Zhang, Yan Jiang, Yu He, Xiaowu Li
Pages: 755-763 Published online on: 11 June 2014
Article
shRNA targeting Bmi-1 sensitizes CD44+ nasopharyngeal cancer stem-like cells to radiotherapy
Xin-Hua Xu, Xiao-Yan Liu, Jin Su, Dao-Jun Li, Qiao Huang, Ming‑Qian Lu, Fang Yi, Jing-Hua Ren, Wei-Hong Chen
Pages: 764-770 Published online on: 13 June 2014
Article
Wnt5a promotes vasculogenic mimicry and epithelial-mesenchymal transition via protein kinase Cα in epithelial ovarian cancer
Hong Qi, Baocun Sun, Xiulan Zhao, Jing Du, Qiang Gu, Yanrong Liu, Runfen Cheng, Xueyi Dong
Pages: 771-779 Published online on: 04 June 2014
Article
Resistance of oral squamous cell carcinoma cells to cetuximab is associated with EGFR insensitivity and enhanced stem cell-like potency
Yuichi Ohnishi, Yuki Minamino, Kenji Kakudo, Masami Nozaki
Pages: 780-786 Published online on: 12 June 2014
Article
Modulation of microRNAs by ionizing radiation in human gastric cancer
Jinpeng He, Junrui Hua, Nan Ding, Shuai Xu, Rui Sun, Guangming Zhou, Xiaodong Xie, Jufang Wang
Pages: 787-793 Published online on: 11 June 2014
Article
Chemokine receptor 7 enhances cell chemotaxis and migration of metastatic squamous cell carcinoma of head and neck through activation of matrix metalloproteinase-9
Nan Guo, Fayu Liu, Liangliang Yang, Jinying Huang, Xue Ding, Changfu Sun
Pages: 794-800 Published online on: 06 June 2014
Article
Nuclear expression of p53 in mature tumor endothelium of retinoblastoma
Byung Joo Lee, Jin Hyoung Kim, Dong Hyun Jo, Kyu‑Won Kim, Young Suk Yu, Jeong Hun Kim
Pages: 801-807 Published online on: 05 June 2014
Article
Younger age at the time of first metastasis in BRAF-mutated compared to BRAF wild-type melanoma patients
Melanie Saint-Jean, Gaëlle Quereux, Jean-Michel Nguyen, Lucie Peuvrel, Anabelle Brocard, Audrey Vallee, Anne-Chantal Knol, Amir Khammari, Marc G. Denis, Brigitte Dréno
Pages: 808-814 Published online on: 13 June 2014
Article
Aberrant hypomethylation-mediated AGR2 overexpression induces an aggressive phenotype in ovarian cancer cells
Hye Youn Sung, Eun Nam Choi, Dahyun Lyu, Ae Kyung Park, Woong Ju, Jung-Hyuck Ahn
Pages: 815-820 Published online on: 11 June 2014
Article
Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase
Juthika Kundu, Bu Young Choi, Chul-Ho Jeong, Joydeb Kumar Kundu, Kyung-Soo Chun
Pages: 821-828 Published online on: 29 May 2014
Article
Cholangiocarcinoma cell line TK may be useful for the pharmacokinetic study of the chemotherapeutic agent gemcitabine
Minori Kamada, Kohei Akiyoshi, Nobutake Akiyama, Naotake Funamizu, Michiko Watanabe, Kouki Fujioka, Kei-Ichi Ikeda, Yoshinobu Manome
Pages: 829-834 Published online on: 30 May 2014
Article
Minocycline and cisplatin exert synergistic growth suppression on hepatocellular carcinoma by inducing S phase arrest and apoptosis
Fu-Yao Liu, Yan-Hui Wu, Shao-Jun Zhou, Yue-Ling Deng, Zun‑Yi Zhang, Er-Lei Zhang, Zhi-Yong Huang
Pages: 835-844 Published online on: 12 June 2014
Article
Anchorage-independent growth of Ewing sarcoma cells under serum-free conditions is not associated with stem-cell like phenotype and function
Katharina Leuchte, Bianca Altvater, Simeon Hoffschlag, Jenny Potratz, Jutta Meltzer, Dagmar Clemens, Andrea Luecke, Jendrik Hardes, Uta Dirksen, Heribert Juergens, Sareetha Kailayangiri, Claudia Rossig
Pages: 845-852 Published online on: 13 June 2014
Article
Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma
Yaqing Li, Xudong Zhang, Tengpeng Hu, Lijuan Han, Ruping Li, Jianguo Wen, Mingzhi Zhang
Pages: 853-859 Published online on: 06 June 2014
Article