Journal Articles

Review Open Access

Human cancer databases (Review)

Athanasia Pavlopoulou, Demetrios A. Spandidos, Ioannis Michalopoulos

Pages: 3-18 Published online on: 31 October 2014
Article Open Access

Activation of the mTOR signaling pathway in breast cancer MCF‑7 cells by a peptide derived from Porphyra yezoensis

Su-Jin Park, Jina Ryu, In-Hye Kim, Youn-Hee Choi, Taek-Jeong Nam

Pages: 19-24 Published online on: 20 October 2014
Article Open Access

A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study

Nicholas B. Blackburn, Jac C. Charlesworth, James R. Marthick, Elizabeth M. Tegg, Katherine A. Marsden, Velandai Srikanth, John Blangero, Ray M. Lowenthal, Simon J. Foote, Joanne L. Dickinson

Pages: 25-32 Published online on: 24 October 2014
Article Open Access

L-glutamine decreases the severity of mucositis induced by chemoradiotherapy in patients with locally advanced head and neck cancer: A double-blind, randomized, placebo-controlled trial

Takae Tsujimoto, Yoshifumi Yamamoto, Masafumi Wasa, Yukinori Takenaka, Susumu Nakahara, Tastuya Takagi, Mamiko Tsugane, Noriyuki Hayashi, Kazuhisa Maeda, Hidenori Inohara, Etsuko Uejima, Toshinori Ito

Pages: 33-39 Published online on: 23 October 2014
Article Open Access

Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer

Yan-Shen Shan, Yi-Ling Chen, Ming-Derg Lai, Hui-Ping Hsu

Pages: 40-48 Published online on: 04 November 2014
Article Open Access

Increased expression of argininosuccinate synthetase protein predicts poor prognosis in human gastric cancer

Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Yi-Pey Luo, Yi-Ling Chen

Pages: 49-57 Published online on: 20 October 2014
Article Open Access

Angiopoietin-like protein 2 induces androgen-independent and malignant behavior in human prostate cancer cells

Ryuta Sato, Mutsushi Yamasaki, Kenichi Hirai, Takanori Matsubara, Takeo Nomura, Fuminori Sato, Hiromitsu Mimata

Pages: 58-66 Published online on: 03 November 2014
Article Open Access

Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3

Shiori Kubota, Mitsuru Chiba, Miki Watanabe, Maki Sakamoto, Narumi Watanabe

Pages: 67-73 Published online on: 13 November 2014
Article

Cyclooxygenase-2 genetic variants influence intratumoral infiltration of Foxp3-positive regulatory T cells in non-small cell lung cancer

Takuro Yukawa, Katsuhiko Shimizu, Ai Maeda, Koichiro Yasuda, Shinsuke Saisho, Riki Okita, Masao Nakata

Pages: 74-80 Published online on: 22 October 2014
Article

Overview and evaluation of the value of fine needle aspiration cytology in determining the histogenesis of liver nodules: 14 years of experience at Hannover Medical School

B. Soudah, A. Schirakowski, M. Gebel, A. Potthoff, P. Braubach, J. Schlue, T. Krech, M. E. Dämmrich, H. H. Kreipe, M. Abbas

Pages: 81-87 Published online on: 20 October 2014
Article

Clinical significance of the FIB-4 index for non-B non-C hepatocellular carcinoma treated with surgical resection

Hiroki Nishikawa, Yukio Osaki, Hideyuki Komekado, Azusa Sakamoto, Sumio  Saito, Norihiro Nishijima, Akihiro Nasu, Akira Arimoto, Ryuichi Kita, Toru Kimura

Pages: 88-94 Published online on: 30 October 2014
Article

Specific growth inhibition of ErbB2‑expressing human breast cancer cells by genetically modified NK‑92 cells

Hui Liu, Bo Yang, Tingting Sun, Lin Lin, Yi Hu, Muhong Deng, Junlan Yang, Tianyi Liu, Jinyu Li, Shengjie Sun, Shunchang Jiao

Pages: 95-102 Published online on: 17 October 2014
Article

Programmed cell death 2 protein induces gastric cancer cell growth arrest at the early S phase of the cell cycle and apoptosis in a p53-dependent manner

Jian Zhang, Wei Wei, Hui-Cheng Jin, Rong-Chao Ying, A-Kao Zhu, Fang-Jie Zhang

Pages: 103-110 Published online on: 17 October 2014
Article

Potent antitumor activity of the Ad5/11 chimeric oncolytic adenovirus combined with interleukin-24 for acute myeloid leukemia via induction of apoptosis

Xubin Wei, Li Liu, Gang Wang, Wei Li, Ke Xu, Hongyan Qi, Hong Liu, Jing Shen, Zhongjie Li, Jimin Shao

Pages: 111-118 Published online on: 22 October 2014
Article

Downregulation of Ras GTPase‑activating protein 1 is associated with poor survival of breast invasive ductal carcinoma patients

Yang Liu, Tong Liu, Qian Sun, Ming Niu, Yang Jiang, Da Pang

Pages: 119-124 Published online on: 13 November 2014
Article

Antitumor effect of photodynamic therapy with a novel targeted photosensitizer on cervical carcinoma

Peng-Xi Li, Jiang-Hong Mu, Hua-Lang Xiao, Dong-Hong Li

Pages: 125-132 Published online on: 07 November 2014
Article

Ubiquitin specific protease 22 promotes cell proliferation and tumor growth of epithelial ovarian cancer through synergy with transforming growth factor β1

Mei Ji, Huirong Shi, Ya Xie, Zhao Zhao, Shunshuang Li, Cheng Chang, Xinghan Cheng, Yue Li

Pages: 133-140 Published online on: 03 November 2014
Article

Overexpression of ZFX and its involvement in squamous cell carcinoma of the tongue

Jirong Yin, Yi Jiang, Hao  Wu, Juncheng  Wang, Shanchuang  Zhang, Hongchen Liu

Pages: 141-148 Published online on: 29 October 2014
Article

Slug promotes hepatocellular cancer cell progression by increasing sox2 and nanog expression

Xiulan Zhao, Baocun Sun, Dan Sun, Tieju Liu, Na Che, Qiang Gu, Xueyi Dong, Rui Li, Yanrong Liu, Jing Li

Pages: 149-156 Published online on: 22 October 2014
Article

Effects of the suppression of lactate dehydrogenase A on the growth and invasion of human gastric cancer cells

Xiaojun Liu, Zhongxia Yang, Zhaofeng Chen, Rui Chen, Da Zhao, Yongning Zhou, Liang Qiao

Pages: 157-162 Published online on: 12 November 2014
Article

Anti-angiogenic effect of tanshinone IIA involves inhibition of the VEGF/VEGFR2 pathway in vascular endothelial cells

Yingying Xing, Jiajie Tu, Lufeng Zheng, Le Guo, Tao Xi

Pages: 163-170 Published online on: 07 November 2014
Article

Establishment of a Langerhans cell histiocytosis lesion cell line with dermal dendritic cell characteristics

Ichiro Murakami, Jean Gogusev, Francis Jaubert, Michiko Matsushita, Kazuhiko Hayashi, Ikuo Miura, Takehiro Tanaka, Takashi Oka, Tadashi Yoshino

Pages: 171-178 Published online on: 24 October 2014
Article

Novel syngeneic mouse mammary carcinoma cell lines from aggressive ErbB2/Neu-overexpressing/PTEN-deficient tumors

Qingfei Wang, Hui Ding, Hai Wang, Ping Li, Baorui  Liu, Kui Zhang

Pages: 179-184 Published online on: 30 October 2014
Article

Effect of Smad3/4 on chemotherapeutic drug sensitivity in colorectal cancer cells

Sung Ung Moon, Mi Hyun Kang, Ji Hea Sung, Jin Won Kim, Jeong Ok Lee, Yu Jung Kim, Keun Wook Lee, Soo Mee Bang, Jong Seok Lee, Jee Hyun Kim

Pages: 185-192 Published online on: 03 November 2014
Article

A novel human interleukin-24 peptide created by computer-guided design contributes to suppression of proliferation in esophageal squamous cell carcinoma Eca-109 cells

Qunfeng Ma, Xuefeng Deng, Bangming Jin, Yao Zhang, Dan Luo, Heyu Song, Pengkun Wang, Chi Zhang, Xue Li, Yinan Shi, Yan Liu, Zhinan Chen, Ziling Wang, Hong Jiang

Pages: 193-200 Published online on: 04 November 2014
Article

DJ-1 knockdown inhibits growth and xenograft‑induced tumor generation of human hepatocellular carcinoma cells

Shunfang Liu, Guoxian Long, Honglan Wei, Lei Shi, Zhifang Yang, Dongbo Liu, Guoqing Hu, Hong Qiu

Pages: 201-206 Published online on: 07 November 2014
Article

Role of gap junction intercellular communication in testicular leydig cell apoptosis induced by oxaliplatin via the mitochondrial pathway

Xuhui Tong, Xi Han, Binbin Yu, Meiling Yu, Guojun Jiang, Jie Ji, Shuying Dong

Pages: 207-214 Published online on: 29 October 2014
Article

Analysis of the amount of tissue sample necessary for mitotic count and Ki-67 index in gastrointestinal stromal tumor sampling

Hideki Kobara, Hirohito Mori, Kazi Rafiq, Shintaro Fujihara, Noriko Nishiyama, Taiga Chiyo, Tae Matsunaga, Maki Ayaki, Tatsuo Yachida, Kiyohito Kato, Hideki Kamada, Koji Fujita, Asahiro Morishita, Makoto Oryu, Kunihiko Tsutsui, Hisakazu Iwama, Yoshio Kushida, Reiji Haba, Tsutomu Masaki

Pages: 215-222 Published online on: 14 November 2014
Article

Kazinol C from Broussonetia kazinoki activates AMP-activated protein kinase to induce antitumorigenic effects in HT-29 colon cancer cells

Hak-Su Kim, Jihyun Lim, Da Yeon Lee, Jae-Ha Ryu, Jong-Seok Lim

Pages: 223-229 Published online on: 12 November 2014
Article

Comparative effects of SNX-7081 and SNX-2112 on cell cycle, apoptosis and Hsp90 client proteins in human cancer cells

Xiao Wang, Shaoxiang Wang, Yuting Liu, Dane Huang, Kai Zheng, Yi Zhang, Xiaoyan Wang, Qiuying Liu, Depo Yang, Yifei Wang

Pages: 230-238 Published online on: 20 October 2014
Article

In vitro synergistic antitumor efficacy of sequentially combined chemotherapy/icotinib in non‑small cell lung cancer cell lines

Min‑Cong Wang, Xuan Liang, Zhi‑Yan Liu, Jie Cui, Ying Liu, Li Jing, Li‑Li Jiang, Jie‑Qun Ma, Li‑Li Han, Qian‑Qian Guo, Cheng‑Cheng Yang, Jing Wang, Tao Wu, Ke‑Jun Nan, Yu Yao

Pages: 239-249 Published online on: 03 November 2014
Article

Expression of special AT-rich sequence-binding protein 1 is an independent prognostic factor in cutaneous T-cell lymphoma

Dariusz Grzanka, Maciej Gagat, Magdalena Izdebska, Andrzej Marszałek

Pages: 250-266 Published online on: 11 November 2014
Article

Identification of novel epigenetically inactivated gene PAMR1 in breast carcinoma

Paulisally Hau Yi Lo, Chizu Tanikawa, Toyomasa Katagiri, Yusuke Nakamura, Koichi Matsuda

Pages: 267-273 Published online on: 03 November 2014
Article

Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression

Fu-Biao Kang, Ling Wang, Dong Li, Yin-Ge Zhang, Dian-Xing Sun

Pages: 274-282 Published online on: 04 November 2014
Article

Loss of function of SWI/SNF chromatin remodeling genes leads to genome instability of human lung cancer

Hai-Tao Huang, Shao-Mu Chen, Liang-Bin Pan, Jie Yao, Hai-Tao Ma

Pages: 283-291 Published online on: 03 November 2014
Article

Vaccination with OVA-bound nanoparticles encapsulating IL-7 inhibits the growth of OVA-expressing E.G7 tumor cells in vivo

Hiroko Toyota, Noriko Yanase, Takayuki Yoshimoto, Mitsunori Harada, Yasuki Kato, Junichiro Mizuguchi

Pages: 292-296 Published online on: 12 November 2014
Article

Molecular mechanism of epigallocatechin-3-gallate in human esophageal squamous cell carcinoma in vitro and in vivo

Lifeng Liu, Lei Hou, Shanzhi Gu, Xiaoxiao Zuo, Du Meng, Minna  Luo, Xiaojin Zhang, Shangke Huang, Xinhan Zhao

Pages: 297-303 Published online on: 20 October 2014
Article

Evaluation of melatonin treatment in primary culture of canine mammary tumors

Juliana Ramos Lopes, Larissa Bazela Maschio, Bruna Victorasso Jardim-Perassi, Marina Gobbe Moschetta, Lívia Carvalho Ferreira, Gustavo Rodrigues Martins, Gabriela Bottaro Gelaleti, Debora Aparecida Pires De Campos Zuccari

Pages: 311-319 Published online on: 11 November 2014
Article

Overexpression of Reg4, alone or combined with MMP-7 overexpression, is predictive of poor prognosis in colorectal cancer

Xingwu Zhu, Yang Han, Chenwei Yuan, Weiwei Tu, Guoqiang Qiu, Su Lu, Huijun Lu, Zhihai Peng, Chongzhi Zhou

Pages: 320-328 Published online on: 22 October 2014
Article

Evaluation of HAAH/humbug quantitative detection in the diagnosis of hepatocellular carcinoma

Tian Xue, Jing Su, Hongmin Li, Xiaoping Xue

Pages: 329-337 Published online on: 13 November 2014
Article

Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo

Yang Sun, Xiufeng Wang, Qianmei Zhou, Yiyu Lu, Hui Zhang, Qilong Chen, Ming Zhao, Shibing Su

Pages: 338-346 Published online on: 03 November 2014
Article

Evaluation of diethylnitrosamine- or hepatitis B virus X gene-induced hepatocellular carcinoma with 18F-FDG PET/CT: A preclinical study

Ju Hui Park, Joo Hyun Kang, Yong Jin Lee, Kwang Il Kim, Tae Sup Lee, Kyeong Min Kim, Ji Ae Park, Yin Ohk Ko, Dae-Yeul Yu, Sang-Soep Nahm, Tae Joo Jeon, Young-Seo Park, Sang Moo Lim

Pages: 347-353 Published online on: 30 October 2014
Article

Functionally distinct subsets of CD4+ regulatory T cells in patients with laryngeal squamous cell carcinoma are indicative of immune deregulation and disease progression

Wei Sun, Wei-Jin Li, Qing-Ling Fu, Chang-You Wu, Ji-Zhen Lin, Xiao-Lin Zhu, Wei-Jian Hou, Yi Wei, Yi-Hui Wen, Yue-Jian Wang, Wei-Ping Wen

Pages: 354-362 Published online on: 20 October 2014
Article

Overexpression of adenylate cyclase-associated protein 1 may predict brain metastasis in non-small cell lung cancer

Shuan-Shuan Xie, Min Tan, Hai-Yan Lin, Lei Xu, Chang-Xing Shen, Qing Yuan, Xiao-Lian Song, Chang-Hui Wang

Pages: 363-371 Published online on: 30 October 2014
Article

Effects of VBMDMP on the reversal of cisplatin resistance in human lung cancer A549/DDP cells

Cheng-Kun Wang, Yang Zhang, Zhi-Jie Zhang, Qin-Wei Qiu, Jian-Guo Cao, Zhi-Min He

Pages: 372-382 Published online on: 13 November 2014
Article

Establishment of human pancreatic cancer gemcitabine‑resistant cell line with ribonucleotide reductase overexpression

Congfei Wang, Weiwei Zhang, Mingjuan Fu, Aiqin Yang, Heguang Huang, Jieming Xie

Pages: 383-390 Published online on: 12 November 2014
Article

Usefulness of plasma HGF level for monitoring acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

Hitomi Umeguchi, Naoko Sueoka-Aragane, Naomi Kobayashi, Tomomi Nakamura, Akemi Sato, Yuji Takeda, Shinichiro Hayashi, Eisaburo Sueoka, Shinya Kimura

Pages: 391-396 Published online on: 22 October 2014
Article

Downregulation of PLZF in human hepatocellular carcinoma and its clinical significance

Anselm Wang-Hei Hui, Hon-Wai Lau, Cyanne Ye Cao, Jun-Wei Zhou, Paul Bo-San Lai, Stephen Kwok-Wing Tsui

Pages: 397-402 Published online on: 30 October 2014
Article

Promotive role of recombinant HE4 protein in proliferation and carboplatin resistance in ovarian cancer cells

Huan Wang, Liancheng Zhu, Jian Gao, Zhenhua Hu, Bei Lin

Pages: 403-412 Published online on: 17 October 2014
Article

Inhibition of basal JNK activity by small interfering RNAs enhances cisplatin sensitivity and decreases DNA repair in T98G glioblastoma cells

Eduardo Parra, Luis Gutiérrez, Jorge Ferreira

Pages: 413-418 Published online on: 24 October 2014
Article

Chelidonium majus L. extract induces apoptosis through caspase activity via MAPK-independent NF-κB signaling in human epidermoid carcinoma A431 cells

Seung-Won Park, Seong Ryul Kim, Youngchul Kim, Jang-Hoon Lee, Hong-Jung Woo, Yeo-Kwang Yoon, Young Il Kim

Pages: 419-424 Published online on: 23 October 2014
Article

Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity

Sulan Li, Dongli Yue, Xinfeng Chen, Liping Wang, Jieyao Li, Yu Ping, Qun Gao, Dan Wang, Tengfei Zhang, Feng Li, Li Yang, Lan Huang, Yi Zhang

Pages: 425-432 Published online on: 24 October 2014
Article

Flavonoids in Ginkgo biloba fallen leaves induce apoptosis through modulation of p53 activation in melanoma cells

Hye-Jung Park, Moon-Moo Kim

Pages: 433-438 Published online on: 12 November 2014
Article

Non-genomic actions of estradiol and 4-OH-tamoxifen on murine breast cancer cells

Diego Raffo, Osvaldo Pontiggia, Elisa Bal de Kier Joffé, Marina Simian

Pages: 439-447 Published online on: 22 October 2014
Article

Synthetic miR-145 mimic inhibits multiple myeloma cell growth in vitro and in vivo Retraction in /10.3892/or.2021.8125

Qi Zhang, Weiqun Yan, Yang Bai, Hao Xu, Changhao Fu, Wenwen Zheng, Yingqiao Zhu, Jie Ma

Pages: 448-456 Published online on: 05 November 2014
Article

Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1α signaling pathway

Fenglin Chen, Mingkai Zhuang, Canmei Zhong, Jun Peng, Xiaozhong Wang, Jianying Li, Zhixin Chen, Yuehong Huang

Pages: 457-463 Published online on: 17 October 2014
Article

In vitro cytotoxicity of 4'-OH-tamoxifen and estradiol in human endometrial adenocarcinoma cells HEC-1A and HEC-1B

Maria E. Cuevas, Tracey E. Lindeman

Pages: 464-470 Published online on: 23 October 2014
Article

Combination of the mTOR inhibitor RAD001 with temozolomide and radiation effectively inhibits the growth of glioblastoma cells in culture

Hélène Burckel, Elodie Josset, Jean-Marc Denis, John Gueulette, Jakobus Slabbert, Georges Noël, Pierre Bischoff

Pages: 471-477 Published online on: 04 November 2014
Article

Treg/Th17 imbalance in malignant pleural effusion partially predicts poor prognosis

Guangdie Yang, Hequan Li, Yinan Yao, Fei Xu, Zhang Bao, Jianying Zhou

Pages: 478-484 Published online on: 30 October 2014
Article

Emerging role of microRNAs in modulating endothelin-1 expression in gastric cancer

Kuo-Wang Tsai, Ling-Yueh Hu, Ting-Wen Chen, Sung-Chou Li, Meng‑Ru Ho, Shou-Yu Yu, Ya-Ting Tu, Wei-Shone Chen, Hing-Chung Lam

Pages: 485-493 Published online on: 11 November 2014
Article

JAK2 inhibitor blocks the inflammation and growth of esophageal squamous cell carcinoma in vitro through the JAK/STAT3 pathway

Juemin Fang, Li Chu, Chunyan Li, Yijing Chen, Fei Hu, Xi Zhang, Huaxin Zhao, Zhuqing Liu, Qing Xu

Pages: 494-502 Published online on: 14 November 2014
Journal Cover

January-2015
Volume 33 Issue 1

Print ISSN: 1021-335X
Online ISSN: 1791-2431

Sign up for eToc alerts

Recommend to Library

Full Size Image