Journal Articles

Retinal ganglion cell death is triggered by paraptosis via reactive oxygen species production: A brief literature review presenting a novel hypothesis in glaucoma pathology

Yao Wang, Kun Xu, Hongbing Zhang, Junhong Zhao, Xiuping Zhu, Yangzheng Wang, Renyi Wu

Pages: 1179-1183 Published online on: 19 June 2014
Open Access

Apogossypolone inhibits the proliferation of LNCaP cells in vitro and in vivo

Xianqing Zhang, Xingbin Hu, Shijie Mu, Yonghua Zhan, Qunxing An, Zhixin Liu, Xiaofeng Huang

Pages: 1184-1194 Published online on: 14 July 2014
Open Access

Pattern of microRNA expression associated with different stages of alcoholic liver disease in rat models

Yi-Peng Chen, Xi Jin, Mei Kong, You-Ming Li

Pages: 1195-1204 Published online on: 07 July 2014
Open Access

Elevated expression of SLC34A2 inhibits the viability and invasion of A549 cells

Weihan Yang, Yu Wang, Qiang Pu, Sujuan Ye, Qingping Ma, Jiang Ren, Guoxing Zhong, Lunxu Liu, Wen Zhu

Pages: 1205-1214 Published online on: 14 July 2014
Open Access

Elevated intracranial dopamine impairs the glutamate‑nitric oxide‑cyclic guanosine monophosphate pathway in cortical astrocytes in rats with minimal hepatic encephalopathy

Saidan Ding, Weilong Huang, Yiru Ye, Jianjing Yang, Jiangnan Hu, Xiaobin Wang, Leping Liu, Qin Lu, Yuanshao Lin

Pages: 1215-1224 Published online on: 16 July 2014

Meglumine cyclic adenylate improves neurological function following acute spinal cord injury in rats

Jingwu Liao, Jingming Xie, Daqiang Lin, Ning Lu, Limin Guo, Weiqiang Li, Bo Pu, Yang Yang, Zhenlong Yang, Ying Zhang, Yueming Song

Pages: 1225-1230 Published online on: 25 June 2014

Diabetes mellitus potentiates diffuse large B‑cell lymphoma via high levels of CCL5

Jingcheng Zhang, Jia Luo, Fanrong Liu, Dongmei Wu, Qingling Zhong, Liangtao Zeng, Ziqing Wu, Tong Zhao, Liqing Wu, Hua Hao

Pages: 1231-1236 Published online on: 17 June 2014
Open Access

Radix Hedysari polysaccharide suppresses lipid metabolism dysfunction in a rat model of non‑alcoholic fatty liver disease via adenosine monophosphate‑activated protein kinase pathway activation

Wei‑Ming Sun, Yu‑Ping Wang, Yong‑Qiang Duan, Hong‑Xia Shang, Wei‑Dong Cheng

Pages: 1237-1244 Published online on: 13 June 2014
Open Access

A SNaPshot assay for the rapid and simple detection of hepatitis B virus genotypes

Guoqi Lai, Wenlu Zhang, Hong Tang, Tingting Zhao, Liwen  Wei, Ying Tao, Zengchan Wang, Ailong Huang

Pages: 1245-1251 Published online on: 14 July 2014

CD8+HLA-DR+ T cells are increased in patients with severe aplastic anemia

Limin Xing, Chunyan Liu, Rong Fu, Huaquan Wang, Jun Wang, Xiao Liu, Le Feng, Lijuan Li, Hui Liu, Honglei Wang, Tian Zhang, Zonghong Shao

Pages: 1252-1258 Published online on: 18 June 2014
Open Access

Diagnosis of ABCB11 gene mutations in children with intrahepatic cholestasis using high resolution melting analysis and direct sequencing

Guorui Hu, Ping He, Zhifeng Liu, Qian Chen, Bixia Zheng, Qihua Zhang

Pages: 1264-1274 Published online on: 20 June 2014
Open Access

Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1‑AS expression

Te Liu, Yongyi Huang, Jiulin Chen, Huiying Chi, Zhihua Yu, Jian Wang, Chuan Chen

Pages: 1275-1281 Published online on: 23 June 2014
Open Access

Transforming growth factor‑β1 reduces apoptosis via autophagy activation in hepatic stellate cells

Mei‑Ya Fu, Ya‑Jun He, Xia Lv, Zhi‑He Liu, Yan Shen, Guo‑Rong  Ye, Yan‑Mei Deng, Jian‑Chang Shu

Pages: 1282-1288 Published online on: 15 July 2014

Galanin receptor 2 utilizes distinct signaling pathways to suppress cell proliferation and induce apoptosis in HNSCC

Takeharu Kanazawa, Kiyoshi Misawa, Yuki Misawa, Mikiko Maruta, Takayuki Uehara, Kazumi Kawada, Takafumi Nagatomo, Keiichi Ichimura

Pages: 1289-1294 Published online on: 04 July 2014

Silencing of hypoxia‑inducible adrenomedullin using RNA interference attenuates hepatocellular carcinoma cell growth in vivo

Fenbao Li, Ruimin Yang, Xizhong Zhang, Aiguang Liu, Yongli Zhao, Yingchang Guo

Pages: 1295-1302 Published online on: 13 June 2014

Carbon dioxide‑pneumoperitoneum in rats reduces ischemia/reperfusion‑induced hepatic apoptosis and inflammatory responses by stimulating sensory neurons

Miho Kawai, Juan Zhao, Hideyuki Ishiguro, Hiromitsu Takeyama

Pages: 1303-1308 Published online on: 16 June 2014

An improved method for guinea pig airway smooth muscle cell culture and the effect of SPFF on intracellular calcium

Jian Liu, Yuyang Zhang, Qian Li, Quankun Zhuang, Xiaojie Zhu, Li Pan, Maosheng Cheng

Pages: 1309-1314 Published online on: 15 July 2014

Curcumin analogues with high activity for inhibiting human prostate cancer cell growth and androgen receptor activation

Dai‑Ying Zhou, Ning Ding, Zhi‑Yun Du, Xiao‑Xing Cui, Hong Wang, Xing‑Chuan Wei, Allan H. Conney, Kun Zhang, Xi Zheng

Pages: 1315-1322 Published online on: 14 July 2014

Melatonin synergized with cyclosporine A improves cardiac allograft survival by suppressing inflammation and apoptosis

Chen Liu, Tao Hong, Mengping Shao, Zhenghang Chen, Chunsheng Wang

Pages: 1323-1328 Published online on: 15 July 2014

Evaluation of vascular grafts based on polyvinyl alcohol cryogels

Maria Teresa Conconi, Luca Borgio, Rosa Di Liddo, Leonardo Sartore, Daniele Dalzoppo, Pietro Amistà, Silvano Lora, Pier Paolo Parnigotto, Claudio Grandi

Pages: 1329-1334 Published online on: 19 June 2014
Open Access

Knockdown of OCT4 suppresses the growth and invasion of pancreatic cancer cells through inhibition of the AKT pathway

Hai Lin, Li‑Hua Sun, Wei Han, Tie‑Ying He, Xin‑Jian Xu, Kun Cheng, Cheng Geng, Li‑Dan Su, Hao Wen, Xi‑Yan Wang, Qi‑Long Chen

Pages: 1335-1342 Published online on: 07 July 2014

Association of intercellular adhesion molecule‑1 gene polymorphism with coronary heart disease

Jun‑Yi Luo, Yi‑Tong Ma, Xiang Xie, Yi‑Ning Yang, Xiao‑Mei Li, Xiang Ma, Zixiang Yu, Bang‑Dang Chen, Fen Liu

Pages: 1343-1348 Published online on: 01 July 2014

Platelet‑derived growth factor promotes osteoblast proliferation by activating G‑protein‑coupled receptor kinase interactor‑1

You Wu, Ying Zhang, Qingshui Yin, Hong Xia, Jiajia Wang

Pages: 1349-1354 Published online on: 14 July 2014

Bioactive components of Glycyrrhiza uralensis mediate drug functions and properties through regulation of CYP450 enzymes

Hao Chen, Xiaomei Zhang, Yifan Feng, Wen Rui, Zhongfeng Shi, Lirong Wu

Pages: 1355-1362 Published online on: 16 June 2014

Photoprotective effect of arctiin against ultraviolet B-induced damage in HaCaT keratinocytes is mediated by microRNA expression changes

Hwa Jun Cha, Ghang Tai Lee, Kwang Sik Lee, Kun Kook Lee, Jin Tae Hong, Na Kyeong Lee, Soo-Yeon Kim, Bo Mi Lee, In-Sook An, Hyung Jin Hahn, Kyu Joong Ahn, Su-Jae Lee, Sungkwan An, Seunghee Bae

Pages: 1363-1370 Published online on: 13 June 2014
Open Access

Tumor necrosis factor-α induces interleukin-34 expression through nuclear factor‑κB activation in MC3T3-E1 osteoblastic cells

Yaqiong Yu, Di Yang, Lihong Qiu, Hirohiko Okamura, Jiajie Guo, Tatsuji Haneji

Pages: 1371-1376 Published online on: 25 June 2014

(-)-Epigallocatechin gallate selectively inhibits adenosine diphosphate‑stimulated human platelet activation: Suppression of heat shock protein 27 phosphorylation via p38 mitogen‑activated protein kinase

Yuko Iida, Tomoaki Doi, Rie Matsushima-Nishiwaki, Haruhiko Tokuda, Shinji Ogura, Osamu Kozawa, Hiroki Iida

Pages: 1383-1388 Published online on: 16 July 2014

RNA interference targeting inhibition of S100A4 suppresses cell growth and promotes apoptosis in human laryngeal carcinoma Hep‑2 cells

Jia Liu, Shuang Fu, Yingqi Xu, Zhihong Zheng

Pages: 1389-1394 Published online on: 19 June 2014

Variation in Sp1 binding sites correlates with expression of survivin in breast cancer

Qing Xu, Mei Liu, Ningzhi Xu, Hongxia Zhu

Pages: 1395-1399 Published online on: 10 July 2014

Anti‑inflammatory effects of Panax notoginseng saponins ameliorate acute lung injury induced by oleic acid and lipopolysaccharide in rats

Yu‑Qing Chen, Ling Rong, Jian‑Ou Qiao

Pages: 1400-1408 Published online on: 16 June 2014

Midkine and syndecan‑1 levels correlate with the progression of malignant gastric cardiac adenocarcinoma

Xiu‑Feng Hu, Jun Yao, She‑Gan Gao, Yan‑Tong Yang, Xiu‑Qing Peng, Xiao‑Shan Feng

Pages: 1409-1415 Published online on: 09 July 2014

Platelet-derived growth factor-β expression in rabbit models of cerebral vasospasm following subarachnoid hemorrhage

Hong-Kai Cui, Rui-Fang Yan, Xiao-Li Ding, Peng Zhao, Qing-Wu Wu, Hong-Po Wang, Hai-Xia Qin, Jian-Fei Tu, Rui-Min Yang

Pages: 1416-1422 Published online on: 20 June 2014

A familial late‑onset hereditary ataxia mimicking pontocerebellar hypoplasia caused by a novel TSEN54 mutation

Yi Qian, Haiyong Wang, Tao Jin, Yiqing Wang, Lizheng  Fang, Yuhao Chen, Liying Chen

Pages: 1423-1425 Published online on: 17 June 2014

MicroRNA-26a inhibits cell proliferation and invasion of cervical cancer cells by targeting protein tyrosine phosphatase type IVA 1

Jing Dong, Long Sui, Qing Wang, Mingjun Chen, Hong Sun

Pages: 1426-1432 Published online on: 16 June 2014

Radioprotective effect of a pan-caspase inhibitor in a novel model of radiation injury to the nucleus of the abducens nerve

Jianguo Li, Li Lin, Liqing Du, Chang Xu, Yan Wang, Jia Cao, Qin Wang, Feiyue Fan, Xiaoping Wang, Yafei Wang, Qiang Liu

Pages: 1433-1437 Published online on: 16 June 2014

c-FLIPp43 induces activation of the nuclear factor‑κB signaling pathway in a dose-dependent manner in the A375 melanoma cell line

Yujue Wang, Yating Tu, Jiejie Lu, Juan Tao, Yan Li

Pages: 1438-1442 Published online on: 07 July 2014

Respiratory syncytial virus infection modulates interleukin‑8 production in respiratory epithelial cells through a transcription factor‑activator protein‑1 signaling pathway

Yao Zhou, Jin Yang, Huan Deng, Hong Xu, Jiamin Zhang, Weisong Jin, Haiyan Gao, Feng Liu, Deyu Zhao

Pages: 1443-1447 Published online on: 26 June 2014

Bone marrow mesenchymal stem cells improve myocardial function in a swine model of acute myocardial infarction

Jing-Jie Zhao, Xiao‑Cheng Liu, Feng Kong, Tong‑Gang  Qi, Guang‑Hui Cheng, Jue Wang, Chao Sun, Yun Luan

Pages: 1448-1454 Published online on: 14 July 2014

Amelioration of doxorubicin‑induced cardiotoxicity by resveratrol

Sameer E. Al‑Harthi, Ohoud M. Alarabi, Wafaa S. Ramadan, Mohamed N. Alaama, Huda M. Al‑Kreathy, Zoheir A. Damanhouri, Lateef M. Khan, Abdel‑Moneim M. Osman

Pages: 1455-1460 Published online on: 15 July 2014

Integrative genomic analyses of secreted protein acidic and rich in cysteine and its role in cancer prediction

Bo Wang, Kai Chen, Wenming Xu, Di Chen, Wei Tang, Tian‑Song Xia

Pages: 1461-1468 Published online on: 17 June 2014

TLR9 and BAFF: Their expression in patients with IgA nephropathy

Weiwei Li, Xiaofei Peng, Yuyuan Liu, Hong Liu, Fuyou Liu, Liyu He, Yang Liu, Fan  Zhang, Chunyan Guo, Guochun Chen, Lei Zhang, Zheng Dong, Youming Peng

Pages: 1469-1474 Published online on: 01 July 2014

miR-137 regulates the migration of human umbilical vein endothelial cells by targeting ephrin-type A receptor 7

Yucheng Lu, Xueyuan Heng, Jixu Yu, Quanping Su, Xianghong  Guan, Cuiping You, Long Wang, Fengyuan Che

Pages: 1475-1480 Published online on: 13 June 2014

In vitro selection and identification of ssDNA aptamers recognizing the Ras protein

Zhi‑Wei Wang, Hong‑Bing Wu, Zhi‑Fu Mao, Xiao‑Ping Hu, Hao Zhang, Zhi‑Peng Hu, Zong‑Li Ren

Pages: 1481-1488 Published online on: 16 June 2014

Nucleolin identified by comparative mass‑spectra analysis is a potential marker for invasive progression of hepatocellular carcinoma

Bin Qian, Yusheng Yao, Yihong Liu, Maolin Yan, Ying Huang, Yanqing Chen

Pages: 1489-1494 Published online on: 13 June 2014

Inhibitory effects of Picrasma quassioides (D.Don) Benn. on airway inflammation in a murine model of allergic asthma

Na‑Rae Shin, In‑Sik Shin, Chan‑Mi Jeon, Ju‑Mi Hong, Sei‑Ryang Oh, Kyu‑Woung Hahn, Kyung‑Seop Ahn

Pages: 1495-1500 Published online on: 13 June 2014

Ulinastatin attenuates renal interstitial inflammation and inhibits fibrosis progression in rats under unilateral ureteral obstruction

Guo-Tao Jiang, Xiao Chen, Dong Li, Hui-Xia An, Jun-Dong Jiao

Pages: 1501-1508 Published online on: 13 June 2014

Estrogen protects cardiomyocytes against lipopolysaccharide by inhibiting autophagy

Fengmei  Wang, Jian Xiao, Yaofeng Shen, Feng Yao, Yu Chen

Pages: 1509-1512 Published online on: 07 July 2014

Podoplanin‑positive cancer cells at the edge of esophageal squamous cell carcinomas are involved in invasion

Jiang-Chao Li, Yan Li, Jiao-Yu Ai, Kai Chen, Ying‑Hui Zhu, Li Fu, Yan-Ru Qin, Li-Jing Wang, Xin-Yuan Guan

Pages: 1513-1518 Published online on: 17 June 2014

Perioperative changes in peripheral regulatory B cells of patients with esophageal cancer

Jiazhen Shi, Shibao Li, Yan Zhou, Lixin Wang, Jiangtao Wen, Yonghong Wang, Zhihua Kang

Pages: 1525-1530 Published online on: 19 June 2014

Naringenin inhibits migration of bladder cancer cells through downregulation of AKT and MMP‑2

Alex Chien Hwa Liao, Chia‑Cheng Kuo, Yei‑Chung Huang, Chi‑Wei Yeh, You‑Cheng Hseu, Jer‑Yuh Liu, Li‑Sung Hsu

Pages: 1531-1536 Published online on: 14 July 2014

microRNA‑802 promotes lung carcinoma proliferation by targeting the tumor suppressor menin

Lun‑Qing Wang, Gang Chen, Xiang‑Yan Liu, Fan‑Ying Liu, Shao‑Yan Jiang, Zhou Wang

Pages: 1537-1542 Published online on: 01 July 2014

Experimental chondrocyte hypertrophy is promoted by the activation of discoidin domain receptor 2

Sihan Zhang, Yu Zhong, Rongheng Li, Wei Wang, Li  Zeng, Zheming Wang, Ping Jia, Rui Wu

Pages: 1543-1548 Published online on: 17 June 2014

Transforming growth factor‑β1 induces epithelial‑mesenchymal transition and increased expression of matrix metalloproteinase‑16 via miR‑200b downregulation in bladder cancer cells

Min Feng Chen, Feng Zeng, Lin Qi, Xiong Bing Zu, Jun Wang, Long Fei Liu, Yuan Li

Pages: 1549-1554 Published online on: 07 July 2014

Expression and effect of CXCL14 in colorectal carcinoma

Kezhi Lin, Ruanmin Zou, Feng Lin, Shuang Zheng, Xian Shen, Xiangyang Xue

Pages: 1561-1568 Published online on: 17 June 2014

Low‑dose radiation‑induced apoptosis in human leukemia K562 cells through mitochondrial pathways

Yong Xin, Hai-Bin Zhang, Tian-You Tang, Gui-Hong Liu, Jian‑She Wang, Guan Jiang, Long‑Zhen Zhang

Pages: 1569-1575 Published online on: 15 July 2014

Berberine attenuates spontaneous action potentials in sinoatrial node cells and the currents of human HCN4 channels expressed in Xenopus laevis oocytes

Hui Chen, Yongjun Chen, Yanhong Tang, Jing Yang, Dandan Wang, Taihui Yu, Congxin Huang

Pages: 1576-1582 Published online on: 14 July 2014

Expression and clinical significance of RCDG1 in renal cell carcinoma: A novel renal cancer‑associated gene

Zuhu Yu, Liangchao Ni, Duqun Chen, Zhengming Su, Wenshui Yu, Qiang  Zhang, Yadong Wang, Cailing Li, Yaoting Gui, Yongqing Lai

Pages: 1583-1589 Published online on: 16 July 2014

Eupolyphaga sinensis Walker demonstrates angiogenic activity and inhibits A549 cell growth by targeting the KDR signaling pathway

Bingling Dai, Junpeng Qi, Rui Liu, Yanmin Zhang

Pages: 1590-1596 Published online on: 16 July 2014

Effects of platycodins on liver complications of type 2 diabetes

Haiyan Luan, Limin Yang, Lei Liu, Shuang Liu, Xiaolian Zhao, Hongyu Sui, Jingtao Wang, Shuqiu Wang

Pages: 1597-1603 Published online on: 04 July 2014

Effect of Substance P on type II alveolar epithelial cells exposed to hyperoxia and its regulation of the Sonic hedgehog signaling pathway

Cong Liu, Lin Yang, Hongxing Dang, Fang Fang, Feng Xu

Pages: 1604-1608 Published online on: 16 June 2014

High‑dose folic acid improves endothelial function by increasing tetrahydrobiopterin and decreasing homocysteine levels

Min Zhang, Jinlin Wen, Xiangjiang Wang, Chun Xiao

Pages: 1609-1613 Published online on: 16 June 2014

Congenital cataracts due to a novel 2‑bp deletion in CRYBA1/A3

Jing Zhang, Yanhua Zhang, Fang Fang, Weihong Mu, Ning  Zhang, Tongshun Xu, Qinying Cao

Pages: 1614-1618 Published online on: 13 June 2014

Recombinant Neisseria surface protein A is a potential vaccine candidate against Neisseria meningitides serogroup B

Shangyun Ying, Jun He, Minjun Yu, Yukuai Zhang, Suhong Deng, Lusi Zhang, Meihua Xie, Sihai Hu

Pages: 1619-1625 Published online on: 13 June 2014

Effects of polycystin‑1 N‑terminal fragment fusion protein on the proliferation and apoptosis of rat mesangial cells

Tianjun Guan, Qing Gao, Ping Chen, Lili Fu, Haidan Zhao, Zhuying Zou, Changlin Mei

Pages: 1626-1634 Published online on: 26 June 2014

Bushen Huoxue decoction improves cognitive decline in rats with cerebral hypoperfusion

Shuifen Ye, Yong Gu, Yihui Xu, Wen Fan, Xiaoting Wang, Shuting Chen, Siyi Cai, Shirong Lv, Yao Tong, Jing Cai

Pages: 1635-1641 Published online on: 26 June 2014

The application of autologous platelet‑rich plasma gel in cartilage regeneration

Aiguo Xie, Lanjun Nie, Gan Shen, Ziwei Cui, Peng Xu, Huaqiang Ge, Qian Tan

Pages: 1642-1648 Published online on: 30 June 2014

Human leptin protein activates the growth of HepG2 cells by inhibiting PERK‑mediated ER stress and apoptosis

Ying Xiong, Jie Zhang, Man Liu, Mingwei An, Ling Lei, Wuhua Guo

Pages: 1649-1655 Published online on: 14 July 2014
Journal Cover

September 2014
Volume 10 Issue 3

Print ISSN: 1791-2997
Online ISSN: 1791-3004

2012 Impact Factor: 1.484
Ranked #59/122 Medicine Research and Experimental
(total number of cites)

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