Journal Articles

Open Access

Gene therapy for ocular diseases meditated by ultrasound and microbubbles (Review)

Caifeng Wan, Fenghua Li, Hongli Li

Pages: 4803-4814 Published online on: 07 July 2015
Open Access

Propofol suppresses proliferation and invasion of glioma cells by upregulating microRNA-218 expression

Jinquan Xu, Weiyun Xu, Jiaqun Zhu

Pages: 4815-4820 Published online on: 01 July 2015
Open Access

MicroRNA let-7b-regulated epidermal stem cell proliferation in hypertrophied anal papillae

Hong Lu, Xiang He, Qingming Wang, De Zheng, Ye Han, Wei Yang, Te Liu

Pages: 4821-4828 Published online on: 02 July 2015
Open Access

Bioinformatics analysis to identify the differentially expressed genes of glaucoma

Xiang Yan, Fei Yuan, Xiuping Chen, Chunqiong Dong

Pages: 4829-4836 Published online on: 02 July 2015
Open Access

Restored expression levels of TET1 decrease the proliferation and migration of renal carcinoma cells

Min Fan, Xiaozhou He, Xianlin Xu

Pages: 4837-4842 Published online on: 08 July 2015
Open Access

Ethyl acetate extract of Hypericum japonicum induces apoptosis via the mitochondria-dependent pathway in vivo and in vitro

Qunchuan Zhuang, Jing Li, Youqin Chen, Jiumao Lin, Faze Lai, Xuzheng Chen, Xindeng Lin, Jun Peng

Pages: 4851-4858 Published online on: 16 July 2015
Open Access

Effect of targeted ovarian cancer therapy using amniotic fluid mesenchymal stem cells transfected with enhanced green fluorescent protein-human interleukin-2 in vivo

Qi You, Yuan Yao, Yuanlong Zhang, Songbin Fu, Mei Du, Guangmei Zhang

Pages: 4859-4866 Published online on: 13 July 2015
Open Access

YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells

Xia Sheng, Wen‑Bin Li, De‑Lin Wang, Ke‑Hong Chen, Jian‑Jia Cao, Zhao Luo, Jiang He, Mei‑Cai Li, Wu‑Jiang Liu, Chao Yu

Pages: 4867-4876 Published online on: 29 June 2015
Open Access

Presence and function of microRNA-92a in chondrogenic ATDC5 and adipose-derived mesenchymal stem cells

Changhe Hou, Ziji Zhang, Zhiqi Zhang, Peihui Wu, Xiaoyi Zhao, Ming Fu, Puyi Sheng, Yan Kang, Weiming Liao

Pages: 4877-4886 Published online on: 01 July 2015
Open Access

Minocycline inhibits PARP‑1 expression and decreases apoptosis in diabetic retinopathy

Ying Wu, Yongdong Chen, Qiang Wu, Lili Jia, Xinhua Du

Pages: 4887-4894 Published online on: 08 July 2015
Open Access

Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70

Wei He, Yun Zhuang, Liangzhi Wang, Lei Qi, Binfang Chen, Mei Wang, Dong Shao, Jianping Chen

Pages: 4895-4900 Published online on: 09 July 2015
Open Access

HOXB7-S3 inhibits the proliferation and invasion of MCF-7 human breast cancer cells

Rui Ma, Dan Zhang, Peng-Chao Hu, Qun Li, Cong-Yao Lin

Pages: 4901-4908 Published online on: 01 July 2015
Open Access

Gonadotropin‑releasing hormone inhibits the proliferation and motility of nasopharyngeal carcinoma cells

Loong Hung Teng, Munirah Ahmad, Wayne Tiong Weng Ng, Subathra Sabaratnam, Maria Ithaya Rasan, Ishwar Parhar, Alan Soo Beng Khoo

Pages: 4909-4916 Published online on: 03 July 2015
Open Access

MicroRNA‑21 regulates the expression of BTG2 in HepG2 liver cancer cells

Bijing Mao, He Xiao, Zhimin Zhang, Dong Wang, Ge Wang

Pages: 4917-4924 Published online on: 07 July 2015
Open Access

Microarray based analysis of gene regulation by microRNA in intervertebral disc degeneration

Peng Hu, Bo Feng, Guanglin Wang, Bin Ning, Tanghong Jia

Pages: 4925-4930 Published online on: 02 July 2015
Open Access

Beneficial reciprocal effects of bone marrow stromal cells and Schwann cells from adult rats in a dynamic co‑culture system in vitro without intercellular contact

Li‑Na Zhou, Xiao‑Jun Cui, Kai‑Xin Su, Xiao‑Hong Wang, Jin‑Hua Guo

Pages: 4931-4938 Published online on: 02 July 2015
Open Access

Ischemic preconditioning maintains the immunoreactivities of glucokinase and glucokinase regulatory protein in neurons of the gerbil hippocampal CA1 region following transient cerebral ischemia

Young Shin Cho, Jun Hwi Cho, Bich‑Na Shin, Geum‑Sil Cho, In Hye Kim, Joon Ha Park, Ji Hyeon Ahn, Taek Geun Ohk, Byung‑Ryul Cho, Young‑Myeong Kim, Seongkweon Hong, Moo‑Ho Won, Jae‑Chul Lee

Pages: 4939-4946 Published online on: 02 July 2015
Open Access

Functional and protein‑protein interaction network analysis of colorectal cancer induced by ulcerative colitis

Yong Dai, Jin‑Bo Jiang, Yan‑Lei Wang, Zu‑Tao Jin, San‑Yuan Hu

Pages: 4947-4958 Published online on: 20 July 2015
Open Access

Transplantation of vascular endothelial growth factor 165‑transfected endothelial progenitor cells for the treatment of limb ischemia

Sheng Wang, Zhong Chen, Xiaobin Tang, Hui Liu, Liao Yang, Yanyang Wang

Pages: 4967-4974 Published online on: 20 July 2015
Open Access

Functional analysis of the nasopharyngeal carcinoma primary tumor‑associated gene interaction network

Fengwei An, Zhiqiang Zhang, Ming Xia

Pages: 4975-4980 Published online on: 20 July 2015
Open Access

Effects of brain‑derived neurotrophic factor and neurotrophin‑3 on the neuronal differentiation of rat adipose‑derived stem cells

Wenchen Ji, Xiaowei Zhang, Le Ji, Kunzheng Wang, Yusheng Qiu

Pages: 4981-4988 Published online on: 20 July 2015
Open Access

MicroRNA‑20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing early growth response 2 expression

Wenkun Zhuo, Weiming Ge, Guolin Meng, Shuaijun Jia, Xiang Zhou, Jian Liu

Pages: 4989-4994 Published online on: 20 July 2015
Open Access

Galectin-3-induced oxidized low-density lipoprotein promotes the phenotypic transformation of vascular smooth muscle cells

Lei Tian, Kan Chen, Jiatian Cao, Zhihua Han, Lin Gao, Yue Wang, Yuqi Fan, Changqian Wang

Pages: 4995-5002 Published online on: 13 July 2015
Open Access

Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells

Victor Aguiriano‑Moser, Bernhard Svejda, Zeng‑Xia Li, Sonja Sturm, Hermann Stuppner, Elisabeth Ingolic, Harald Höger, Veronika Siegl, Nathalie Meier-Allard, Anton Sadjak, Roswitha Pfragner

Pages: 5003-5011 Published online on: 07 July 2015
Open Access

MicroRNA‑197 reverses the drug resistance of fluorouracil‑induced SGC7901 cells by targeting mitogen‑activated protein kinase 1

Hai‑Lin Xiong, Si‑Wei Zhou, Ai‑Hua Sun, Ying He, Jun Li, Xia Yuan

Pages: 5019-5025 Published online on: 07 July 2015
Open Access

Protective effects of SS31 on t‑BHP induced oxidative damage in 661W cells

Wei Ma, Xiaobo Zhu, Xiaoyan Ding, Tao Li, Yijun Hu, Xuting Hu, Lin Yuan, Lei Lei, Andina Hu, Yan Luo, Shibo Tang

Pages: 5026-5034 Published online on: 07 July 2015
Open Access

Promotion of mitochondrial energy metabolism during hepatocyte apoptosis in a rat model of acute liver failure

Li‑Yan Chen, Baoshan Yang, Li Zhou, Feng Ren, Zhong‑Ping Duan, Ying‑Ji Ma

Pages: 5035-5041 Published online on: 02 July 2015
Open Access

Aberrant Wnt/β‑catenin signaling and elevated expression of stem cell proteins are associated with osteosarcoma side population cells of high tumorigenicity

Xi‑Jun Yi, Yu‑Hua Zhao, Li‑Xiang Qiao, Chun‑Lei Jin, Jing Tian, Qiu‑Shi Li

Pages: 5042-5048 Published online on: 02 July 2015
Open Access

Substrate-specific gene expression profiles in different kidney cell types are associated with Fabry disease

Youn‑Jeong Shin, Yeo Jin Jeon, Namhee Jung, Joo‑Won Park, Hae‑Young Park, Sung‑Chul Jung

Pages: 5049-5057 Published online on: 01 July 2015
Open Access

A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms

Jianping Jia, Song Dai, Xinghe Sun, Yuehong Sang, Zhenming Xu, Jie Zhang, Xiaofeng Cui, Jinhui Song, Xing Guo

Pages: 5058-5064 Published online on: 08 July 2015
Open Access

Cardiac effects of the c.1583 C→G LMNA mutation in two families with Emery‑Dreifuss muscular dystrophy

Li Zhang, Hongrui Shen, Zhe Zhao, Qi Bing, Jing Hu

Pages: 5065-5071 Published online on: 08 July 2015
Open Access

Steatocystoma multiplex is associated with the R94C mutation in the KRTl7 gene

Qiao Liu, Weiwei Wu, Jiejie Lu, Ping Wang, Feng Qiao

Pages: 5072-5076 Published online on: 08 July 2015
Open Access

Effects of Ras homolog gene family, member C gene silencing combined with rapamycin on hepatocellular carcinoma cell growth

Shu‑Li Xie, Ming‑Guang Zhu, Guo‑Fu Chen, Guang‑Yi Wang, Guo‑Yue Lv

Pages: 5077-5085 Published online on: 08 July 2015
Open Access

Girdin regulates the migration and invasion of glioma cells via the PI3K‑Akt signaling pathway

Weimin Ni, Yan Fang, Lei Tong, Zhaoxue Tong, Fuxin Yi, Jianwu Qiu, Rui Wang, Xiaojie Tong

Pages: 5086-5092 Published online on: 07 July 2015
Open Access

Genetically modified human placenta‑derived mesenchymal stem cells with FGF‑2 and PDGF‑BB enhance neovascularization in a model of hindlimb ischemia

Tao Yin, Sisi He, Chao Su, Xiancheng Chen, Dongmei Zhang, Yang Wan, Tinghong Ye, Guobo Shen, Yongsheng Wang, Huashan Shi, Li Yang, Yuquan Wei

Pages: 5093-5099 Published online on: 20 July 2015
Open Access

8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao

Pages: 5100-5108 Published online on: 03 July 2015

Hepatitis C virus NS3 protein modulates the biological behaviors of malignant hepatocytes by altering the expression of host cell microRNA

Jun Zhang, Yasuhito Ishigaki, Tsutomu Takegami

Pages: 5109-5115 Published online on: 03 July 2015

Expression of nephrin in the human placenta and fetal membranes

Bo Hyon Yun, Seung Mi Lee, Hee Young Cho, Ji Young Kim, Ga Hyun Son, Young Han Kim, Yong Won Park, Beom Jin Lim, Ja Young Kwon

Pages: 5116-5120 Published online on: 06 July 2015

MicroRNA‑506 participates in pancreatic cancer pathogenesis by targeting PIM3

Jundong Du, Xi Zheng, Shouwang Cai, Ziman Zhu, Jingwang Tan, Bin Hu, Zhiqiang Huang, Huabo Jiao

Pages: 5121-5126 Published online on: 22 July 2015

Derivation and growth characteristics of dental pulp stem cells from patients of different ages

Wei Wu, Jian Zhou, Chong‑Tao Xu, Jie Zhang, Yan‑Jiao Jin, Geng‑Lin Sun

Pages: 5127-5134 Published online on: 21 July 2015

Upregulation of microRNA‑138‑5p inhibits pancreatic cancer cell migration and increases chemotherapy sensitivity

Chao Yu, Min Wang, Meiyuan Chen, Yang Huang, Jianxin Jiang

Pages: 5135-5140 Published online on: 02 July 2015

Biological characteristics of the A1762T/G1764A mutant strain of hepatitis B virus in vivo

Xiao‑Hua Leng, En‑Qiang Chen, Ling‑Yao Du, Lang Bai, Dao‑Ying Gong, Xing Cheng, Fei‑Jun Huang, Hong Tang

Pages: 5141-5148 Published online on: 09 July 2015

A novel endoplasmic reticulum stress‑induced apoptosis model using tunicamycin in primary cultured neonatal rat cardiomyocytes

Mingzhi Shen, Lin Wang, Xiaowang Guo, Qiao Xue, Cong Huo, Xing Li, Li Fan, Xiaoming Wang

Pages: 5149-5154 Published online on: 03 July 2015

A novel brain metastasis xenograft model for convection‑enhanced delivery of targeted toxins via a micro‑osmotic pump system enabled for real‑time bioluminescence imaging

Jun Huang, Yan Michael Li, Quan Cheng, Daniel A. Vallera, Walter A. Hall

Pages: 5163-5168 Published online on: 22 July 2015

Dronedarone does not affect infarct volume as assessed by magnetic resonance imaging in a porcine model of myocardial infarction

Josefine Linke, Kirsten Utpatel, Carmen Wolke, Matthias Evert, Jens‑Peter Kühn, Alicja Bukowska, Andreas Goette, Uwe Lendeckel, Barbara Peters

Pages: 5169-5178 Published online on: 13 July 2015

Comparison of ovarian cancer markers in endometriosis favours HE4 over CA125

Brett Mckinnon, Michael D. Mueller, Konstantinos Nirgianakis, Nick A. Bersinger

Pages: 5179-5184 Published online on: 08 July 2015

Coupled aggregation of mitochondrial single-strand DNA-binding protein tagged with Eos fluorescent protein visualizes synchronized activity of mitochondrial nucleoids

Tomáš Olejár, David Pajuelo‑Reguera, Lukáš Alán, Andrea Dlasková, Petr Ježek

Pages: 5185-5190 Published online on: 16 July 2015

Decoy receptor 3 regulates the expression of tryptophan hydroxylase 1 in rheumatoid synovial fibroblasts

Toshihisa Maeda, Yasushi Miura, Koji Fukuda, Shinya Hayashi, Masahiro Kurosaka

Pages: 5191-5196 Published online on: 20 July 2015

Hydrogen sulfide attenuates doxorubicin‑induced cardiotoxicity by inhibiting calreticulin expression in H9c2 cells

Mi‑Hua Liu, Yuan Zhang, Xiao‑Long Lin, Jun He, Tian‑Ping Tan, Shao‑Jian Wu, Shan Yu, Li Chen, Yu‑Dan Chen, Hong‑Yun Fu, Cong Yuan, Jian Li

Pages: 5197-5202 Published online on: 02 July 2015

Lysophosphatidic acid increases the proliferation and migration of adipose‑derived stem cells via the generation of reactive oxygen species

Sangjin Kang, Juhee Han, Seung Yong Song, Won‑Serk Kim, Soyoung Shin, Ji Hye Kim, Hyosun Ahn, Jin‑Hyun Jeong, Sung‑Joo Hwang, Jong‑Hyuk Sung

Pages: 5203-5210 Published online on: 02 July 2015

Identification of genes associated with osteoarthritis by microarray analysis

Jianwei Sun, Bingshan Yan, Wangping Yin, Xinchao Zhang

Pages: 5211-5216 Published online on: 07 July 2015

Tyrosylprotein sulfotransferase 1 expression is negatively correlated with c‑Met and lymph node metastasis in human lung cancer

Zhibin Jiang, Jialiang Zhu, Yuchao Ma, Cao Hong, Sheng Xiao, Longyu Jin

Pages: 5217-5222 Published online on: 20 July 2015

Inhibitory effect of 2‑mercaptoethane sulfonate on the formation of Escherichia coli biofilms in vitro

Sheng Chen, Nianhai He, Jialin Yu, Luquan Li, Fengjun Sun, Ying Hu, Rui Deng, Shiming Zhong, Leilei Shen

Pages: 5223-5230 Published online on: 22 July 2015

Nuclear transcription factor CDX2 inhibits gastric cancer‑cell growth and reverses epithelial‑to‑mesenchymal transition in vitro and in vivo

Jian‑Feng Zhang, Li‑Shuai Qu, Xue‑Fen Qian, Bei‑Lei Xia, Zhen‑Biao Mao, Wei‑Chang Chen

Pages: 5231-5238 Published online on: 22 July 2015

Immunohistochemical analysis of phosphorylated mammalian target of rapamycin and its downstream signaling components in invasive breast cancer

Bin‑Lin Ma, Mei‑Hui Shan, Gang Sun, Guang‑Hui Ren, Chao Dong, Xuemei Yao, Mei Zhou

Pages: 5246-5254 Published online on: 03 July 2015

MicroRNA‑34a attenuates the proliferation, invasion and metastasis of gastric cancer cells via downregulation of MET

Bin Wei, Qiao Ying Huang, Shun Rong Huang, Wei Mai, Xiao Gang Zhong

Pages: 5255-5261 Published online on: 22 July 2015

Involvement of Kruppel-like factor 9 in bleomycin-induced pulmonary toxicity

Yue Gu, Yan‑Bing Wu, Li‑Hui Wang, Jia‑Ning Yin

Pages: 5262-5266 Published online on: 02 July 2015

Hypoxia promotes the proliferation of MC3T3-E1 cells via the hypoxia-inducible factor-1α signaling pathway

Lichao Wang, Buling Wu, Yu Zhang, Zhihui Tian

Pages: 5267-5273 Published online on: 03 July 2015

MicroRNA-215 is upregulated by treatment with Adriamycin and leads to the chemoresistance of hepatocellular carcinoma cells and tissues

Li Wang, Yan Ming Wang, Song Xu, Wei Guo Wang, Yang Chen, Jing Yu Mao, Bo Le Tian

Pages: 5274-5280 Published online on: 01 July 2015

Effects of two novel amino acid substitutions on the penicillin binding properties of the PBP5 C‑terminal from Enterococcus faecium

Chengjiang Zhou, Haiying Niu, Hui Yu, Lishe Zhou, Zhanli Wang

Pages: 5281-5285 Published online on: 08 July 2015

Inhibitory effect of zinc on the advanced glycation end product-induced apoptosis of mouse osteoblastic cells

Mingyue Xiong, Liqiang Liu, Zhenhui Liu, Hangfei Gao

Pages: 5286-5292 Published online on: 17 July 2015

Increased expression of Notch 1 in a rat liver transplantation model

Lihong Chen, Wubing He, Kaida Huang, Lin Zheng, Lingyun Gao, Jingfeng Liu, Aimin Huang

Pages: 5293-5297 Published online on: 02 July 2015

Practical assessment of the quantification of atherosclerotic lesions in apoE‑/‑ mice

Yan Lin, Liang Bai, Yulong Chen, Ninghong Zhu, Yanping Bai, Qianwei Li, Sihai Zhao, Jianglin Fan, Enqi Liu

Pages: 5298-5306 Published online on: 16 July 2015

House dust mite allergens mediate the activation of c‑kit in dendritic cells via Toll‑like receptor 2

Wei Wu, Chun‑Xia Wang, Hui Chen, Jing Zhou, Jin‑Zhao Zhang, Lin Gao, Hong‑Yan Zhou

Pages: 5307-5313 Published online on: 20 July 2015

Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2‑deoxy‑D‑ribose‑induced β‑cell damage

Gwanpyo Koh, Eun‑Jin Yang, Ji Young Kim, Jonghoon Hyun, Soyeon Yoo, Sang Ah Lee

Pages: 5314-5320 Published online on: 06 July 2015

Yiqi Huaju formula, a Chinese herbal medicine, reduces arterial pressure in salt‑sensitive hypertension by inhibiting renin‑angiotensin system activation

Yan‑Ming He, Hong‑Jie Yang, Qiang Yang, Jin‑Gang Cui, Tian‑Zhan Wang, Yi Chen, Pei‑Wei Wang, Teng Zhang, Wen‑Jian Wang

Pages: 5321-5327 Published online on: 20 July 2015

Synergistic neuroprotective effect of microglial‑conditioned media treated with geniposide and ginsenoside Rg1 on hypoxia injured neurons

Jun Wang, Jincai Hou, Hongtao Lei, Jianhua Fu, Yanshu Pan, Jianxun Liu

Pages: 5328-5334 Published online on: 20 July 2015

LOX‑1 is implicated in oxidized low‑density lipoprotein‑induced oxidative stress of macrophages in atherosclerosis

Hui‑Yu Yang, Yun‑Fei Bian, Hua‑Ping Zhang, Fen Gao, Chuan‑Shi Xiao, Bin Liang, Jin Li, Na‑Na Zhang, Zhi‑Ming Yang

Pages: 5335-5341 Published online on: 08 July 2015

Oxidative damage to human parametrial ligament fibroblasts induced by mechanical stress

Shasha Hong, Li Hong, Debin Wu, Bingshu Li, Cheng Liu, Wenjun Guo, Jie Min, Ming Hu, Yang Zhao, Qing Yang

Pages: 5342-5348 Published online on: 23 July 2015

Carvacrol protects against spinal cord injury in rats via suppressing oxidative stress and the endothelial nitric oxide synthase pathway

Zhen‑Song Jiang, Zhi‑Chen Pu, Zhen‑Hai Hao

Pages: 5349-5354 Published online on: 06 July 2015

Chondrogenic differentiation of bone marrow‑derived stem cells cultured in the supernatant of elastic cartilage cells

Xiaodie Zhang, Ke Xue, Jia Zhou, Peng Xu, Huizhen Huang, Kai Liu

Pages: 5355-5360 Published online on: 22 July 2015

Networks of micrornas and genes in acute lymphoblastic leukemia

Yuhua Xie, Zhiwen Xu, Kunhao Wang, Ning Wang, Yunxiao Wang, Jiwei Bao

Pages: 5361-5368 Published online on: 23 July 2015

Two faces of the estrogen metabolite 2-methoxyestradiol in vitro and in vivo

Ji‑Sun Lee, Yu‑Kyung Kim, Hyun Yang, Hee Young Kang, Changhwan Ahn, Eui‑Bae Jeung

Pages: 5375-5382 Published online on: 13 July 2015

Upregulation of microRNA‑335 and microRNA‑584 contributes to the pathogenesis of severe preeclampsia through downregulation of endothelial nitric oxide synthase

Feng Jiang, Jipeng Li, Guojun Wu, Zhuo Miao, Linshan Lu, Guoping Ren, Xiaohong Wang

Pages: 5383-5390 Published online on: 02 July 2015

Erythropoietin improves glucose metabolism and pancreatic β-cell damage in experimental diabetic rats

Li‑Na Chen, Qiang Sun, Shu‑Qing Liu, Hao Hu, Juan Lv, Wen‑Jun Ji, Meng Wang, Ming‑Xia Chen, Jun Zhou

Pages: 5391-5398 Published online on: 29 June 2015

MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA‑132 in rats with depression

Meilei Su, Jun Hong, Yongzhi Zhao, Shuai Liu, Xiang Xue

Pages: 5399-5406 Published online on: 20 July 2015

Combinational treatment with microRNA‑133b and cetuximab has increased inhibitory effects on the growth and invasion of colorectal cancer cells by regulating EGFR

Jianyu Zhou, Lv Lv, Changwei Lin, Gui Hu, Yihang Guo, Meirong Wu, Buning Tian, Xiaorong Li

Pages: 5407-5414 Published online on: 06 July 2015

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway

Zhiming Zhao, Chenggang Li, Hao Xi, Yuanxing Gao, Dabin Xu

Pages: 5415-5422 Published online on: 08 July 2015

Difference in protective effects of three structurally similar flavonoid glycosides from Hypericum ascyron against H2O2-induced injury in H9c2 cardiomyoblasts

Xiu‑Mei Li, Xue‑Gang Luo, Kun Li, Nan Wang, Er‑Bin Hua, Yao Zhang, Tong‑Cun Zhang

Pages: 5423-5428 Published online on: 15 July 2015

Association of genetic variants with dyslipidemia

Shintaro Abe, Fumitaka Tokoro, Reiko Matsuoka, Masazumi Arai, Toshiyuki Noda, Sachiro Watanabe, Hideki Horibe, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Shinya Minatoguchi, Yoshiji Yamada

Pages: 5429-5436 Published online on: 16 July 2015

Anticancer activity of stoppin based on a novel peptide delivery system

Yan‑Fang Gao, Xue‑Ni Wei, Xiao‑Lei Ye, Guo‑Bin Weng, Yi‑Chen Chen, Ya‑Rong Zhao, Hui Ji

Pages: 5437-5442 Published online on: 02 July 2015

MicroRNA-7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6

Jiashun Luo, Hui Li, Chunfang Zhang

Pages: 5443-5448 Published online on: 02 July 2015

Effects of X‑ray irradiation in combination with ascorbic acid on tumor control

Yoichiro Hosokawa, Satoru Monzen, Hironori Yoshino, Shingo Terashima, Manabu Nakano, Keisuke Toshima, Ryo Saga, Ikuo Kashiwakura

Pages: 5449-5454 Published online on: 22 July 2015

B7‑H3 promotes cell migration and invasion through the Jak2/Stat3/MMP9 signaling pathway in colorectal cancer

Fen Liu, Ting Zhang, Shitao Zou, Bo Jiang, Dong Hua

Pages: 5455-5460 Published online on: 07 July 2015

Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma

Hao Wu, Qiang Liu, Tao Cai, Yu‑Dan Chen, Zhi‑Fei Wang

Pages: 5461-5466 Published online on: 17 July 2015

Cross‑reactivity between group-5 and -21 mite allergens from Dermatophagoides farinae, Tyrophagus putrescentiae and Blomia tropicalis

Chung‑Ryul Kim, Kyoung Yong Jeong, Myung‑Hee Yi, Hyoung‑Pyo Kim, Ho‑Joon Shin, Tai‑Soon Yong

Pages: 5467-5474 Published online on: 20 July 2015

Decreased expression levels of Nurr1 are associated with chronic inflammation in patients with type 2 diabetes

Ying Xu, Qi Huang, Wenfang Zhang, Yaping Wang, Qingling Zeng, Chunyan He, Junli Xue, Jin Chen, Xuemei Hu, Yancheng Xu

Pages: 5487-5493 Published online on: 21 July 2015

Deglucose chikusetsusaponin IVa isolated from Rhizoma Panacis Majoris induces apoptosis in human HepG2 hepatoma cells

Xiaomei Song, Wei Wang, Xin Zhang, Yi Jiang, Xinjie Yang, Chong Deng, Zhenggang Yue, Zhishu Tang

Pages: 5494-5500 Published online on: 03 July 2015

Ascorbic acid inhibits TPA-induced HL‑60 cell differentiation by decreasing cellular H2O2 and ERK phosphorylation

Giou‑Teng Yiang, Jen‑Ni Chen, Tsai‑Kun Wu, Hsueh‑Fang Wang, Yu‑Ting Hung, Wei‑Jung Chang, Chinshuh Chen, Chyou‑Wei Wei, Yung‑Luen Yu

Pages: 5501-5507 Published online on: 20 July 2015

Molecular cloning and characterization of presenilin gene in Bombyx mori

Zeng‑Zhang Zheng, Meng‑Ling Chao, Zong‑Biao Fan, Yi‑Jiao Zhao, Hong‑Sheng Song

Pages: 5508-5516 Published online on: 02 July 2015

Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

Dan Li, Zhitao Xiao, Gang Wang, Xianji Song

Pages: 5517-5523 Published online on: 01 July 2015

Heat shock protein 70 induction by glutamine increases the α‑synuclein degradation in SH‑SY5Y neuroblastoma cells

Jia Yang, Yanmei Zhang, Shigang Zhao, Zhelin Zhang, Xiuqing Tong, Fang Wei, Zuneng Lu

Pages: 5524-5530 Published online on: 02 July 2015

HAND2‑mediated proteolysis negatively regulates the function of estrogen receptor α

Tomohiko Fukuda, Akira Shirane, Osamu Wada‑Hiraike, Katsutoshi Oda, Michihiro Tanikawa, Ayako Sakuabashi, Mana Hirano, Houju Fu, Yoshihiro Morita, Yuichiro Miyamoto, Kanako Inaba, Kei Kawana, Yutaka Osuga, Tomoyuki Fujii

Pages: 5538-5544 Published online on: 09 July 2015

Stimulation of RAW264.7 macrophages by sulfated Escherichia coli K5 capsular polysaccharide in vitro

Liping Teng, Haitian Fu, Min Wang, Chao Deng, Jinghua Chen

Pages: 5545-5553 Published online on: 16 July 2015

MicroRNA-203 inhibits the malignant progression of neuroblastoma by targeting Sam68

Dongju Zhao, Yunjiao Tian, Peiling Li, Limin Wang, Aiju Xiao, Mingqiu Zhang, Taixin Shi

Pages: 5554-5560 Published online on: 01 July 2015

Effects of Wnt/β‑catenin signaling on bisphenol A exposure in male mouse reproductive cells

Zhiqi Fang, Xiaoli Liu, Xiaosi Yang, Xianbin Song, Xiaoyu Chen

Pages: 5561-5567 Published online on: 02 July 2015

Transforming growth factor‑β1 induces type II collagen and aggrecan expression via activation of extracellular signal‑regulated kinase 1/2 and Smad2/3 signaling pathways

Yanhui Zhu, Hairong Tao, Chen Jin, Yonzhang Liu, Xiongwei Lu, Xiaopeng Hu, Xiang Wang

Pages: 5573-5579 Published online on: 09 July 2015

Berberine inhibits tumor necrosis factor‑α‑induced expression of inflammatory molecules and activation of nuclear factor‑κB via the activation of AMPK in vascular endothelial cells

Su‑Jian Liu, Cai‑Xia Yin, Ming‑Chao Ding, Yi‑Zhong Wang, Hong Wang

Pages: 5580-5586 Published online on: 08 July 2015
Open Access

Roles of microRNA-146a and microRNA-181b in regulating the secretion of tumor necrosis factor-α and interleukin-1β in silicon dioxide-induced NR8383 rat macrophages

Yang Zhang, Faxuan Wang, Yajia Lan, Dinglun Zhou, Xiaohui Ren, Liqiang Zhao, Qin Zhang

Pages: 5587-5593 Published online on: 16 July 2015

Human recombinant endostatin Endostar attenuates hepatic sinusoidal endothelial cell capillarization in CCl4‑induced fibrosis in mice

Qi You, Ling‑Jian Kong, Feng‑Dong Li, Hang‑Yu Wang, Dian‑Gang Liu, Feng‑Hua Pei, Ji‑Tao Song, Jun Xu, Jing Chen

Pages: 5594-5600 Published online on: 20 July 2015

[Retracted] Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways

Gongli Yang, Feng Ma, Muxiao Zhong, Lin Fang, Yao Peng, Xiaoming Xin, Jietao Zhong, Wei Zhu, Yali Zhang

Pages: 5601-5601 Published online on: 22 July 2015

[Erratum] Effects of glucose-dependent insulinotropic polypeptide receptor knockout and a high-fat diet on cognitive function and hippocampal gene expression in mice

Rachael Lennox, R. Charlotte Moffett, David W. Porter, Nigel Irwin, Victor A. Gault, Peter R. Flatt

Pages: 5602-5602 Published online on: 15 July 2015

Long non-coding RNA HOTAIR: A novel oncogene (Review)

Xin Yu, Zheng Li

Pages: 5611-5618 Published online on: 31 July 2015
Open Access

Lentivirus‑delivered nemo‑like kinase small interfering RNA inhibits laryngeal cancer cell proliferation in vitro

Jun Tai, Yuansheng Rao, Jugao Fang, Zhigang Huang, Zhenkun Yu, Xiaohong Chen, Weiguo Zhou, Xiao Xiao, Ting Long, Yang Han, Qiaoyin Liu, Aidong Li, Xin Ni

Pages: 5619-5624 Published online on: 06 August 2015
Open Access

Expression pattern of aquaporins in patients with primary nephrotic syndrome with edema

Yu Wang, Jimei Bu, Qing Zhang, Kai Chen, Jihong Zhang, Xiaorong Bao

Pages: 5625-5632 Published online on: 11 August 2015
Open Access

Evaluation of reference gene suitability for quantitative expression analysis by quantitative polymerase chain reaction in the mandibular condyle of sheep

Xin Jiang, Yang Xue, Hongzhi Zhou, Shouhong Li, Zongmin Zhang, Rui Hou, Yuxiang Ding, Kaijin Hu

Pages: 5633-5640 Published online on: 28 July 2015
Open Access

GSK1838705A, an IGF-1R inhibitor, inhibits glioma cell proliferation and suppresses tumor growth in vivo

Xiang Zhou, Fazheng Shen, Pengju Ma, Hongyan Hui, Sujuan Pei, Ming Chen, Zhongwei Wang, Wenke Zhou, Baozhe Jin

Pages: 5641-5646 Published online on: 28 July 2015
Open Access

Analysis of the differential expression of circulating microRNAs during the progression of hepatic fibrosis in patients with chronic hepatitis B virus infection

Qingqing Zhang, Mingyi Xu, Ying Qu, Zhenghong Li, Qidi Zhang, Xiaobo Cai, Lungen Lu

Pages: 5647-5654 Published online on: 12 August 2015
Open Access

1q21.1 microduplication in a patient with mental impairment and congenital heart defect

Guowen Sun, Zhiping Tan, Liangliang Fan, Jian Wang, Yifeng Yang, Weizhi Zhang

Pages: 5655-5658 Published online on: 31 July 2015
Open Access

A duplication upstream of SOX9 was not positively correlated with the SRY‑negative 46,XX testicular disorder of sex development: A case report and literature review

Xin‑Yi Xia, Cui Zhang, Tian‑Fu Li, Qiu‑Yue Wu, Na Li, Wei‑Wei Li, Ying‑Xia Cui, Xiao‑Jun Li, Yi‑Chao Shi

Pages: 5659-5664 Published online on: 10 August 2015
Open Access

Endosialin‑expressing bone sarcoma stem‑like cells are highly tumor‑initiating and invasive

Dong‑Xiu Sun, Guang‑Jun Liao, Ke‑Gui Liu, Han Jian

Pages: 5665-5670 Published online on: 12 August 2015
Open Access

Synergistic effect of a tissue kallikrein 1 and tissue inhibitor of matrix metalloproteinase 1 co‑expression vector on the proliferation of rat vascular smooth muscle cells

Pengli Zhu, Huizhen Yu, Shujie Huang, Hong Xiang, Feng Li, Weiping Zheng

Pages: 5671-5678 Published online on: 07 August 2015
Open Access

Fatsioside A‑induced apoptotic death of HepG2 cells requires activation of AMP‑activated protein kinase

Yu‑Shan Zheng, Jian‑You Zhang, Dong‑Hui Zhang

Pages: 5679-5684 Published online on: 06 August 2015
Open Access

Association between xanthine dehydrogenase tag single nucleotide polymorphisms and essential hypertension

Baogang Wu, Ying Hao, Jin Shi, Ning Geng, Tiejun Li, Yanli Chen, Zhaoqing Sun, Liqiang Zheng, Hong Li, Naijing Li, Xingang Zhang, Yingxian Sun

Pages: 5685-5690 Published online on: 29 July 2015
Open Access

Lentiviral-mediated growth-associated protein-43 modification of bone marrow mesenchymal stem cells improves traumatic optic neuropathy in rats

Qi Zhu, Zaoxia Liu, Chenguang Wang, Lili Nie, Yuxi He, Yan Zhang, Xin Liu, Guanfang Su

Pages: 5691-5700 Published online on: 28 July 2015
Open Access

An in vitro investigation into the role of bone marrow‑derived mesenchymal stem cells in the control of disc degeneration

Jinquan Hu, Guoying Deng, Ye Tian, Yingyan Pu, Peng Cao, Wen Yuan

Pages: 5701-5708 Published online on: 29 July 2015
Open Access

MicroRNA‑34a induces apoptosis in PC12 cells by reducing B‑cell lymphoma 2 and sirtuin‑1 expression

Qiang Lin, Yurong Mao, Yunlin Song, Dongfeng Huang

Pages: 5709-5714 Published online on: 05 August 2015
Open Access

MicroRNA‑205 promotes the tumorigenesis of nasopharyngeal carcinoma through targeting tumor protein p53-inducible nuclear protein 1

Guohui Nie, Hongfang Duan, Xiaoqing Li, Zhendong Yu, Liang Luo, Ruijing Lu, Ziliang Ji, Wei Zhang

Pages: 5715-5722 Published online on: 05 August 2015
Open Access

Prostaglandin E1 protects bone marrow‑derived mesenchymal stem cells against serum deprivation‑induced apoptosis

Kuan Zeng, Bao Ping Deng, Hui‑Qi Jiang, Meng Wang, Ping Hua, Hong‑Wu Zhang, Yu‑Bin Deng, Yan‑Qi Yang

Pages: 5723-5729 Published online on: 05 August 2015
Open Access

N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li

Pages: 5730-5736 Published online on: 03 August 2015
Open Access

Effects of rotigaptide (ZP123) on connexin43 remodeling in canine ventricular fibrillation

Guo-Ying Su, Jing Wang, Zhen-Xing Xu, Xiao-Jun Qiao, Jing-Quan Zhong, Yun Zhang

Pages: 5746-5752 Published online on: 06 August 2015
Open Access

Expression of microRNA‑26b and identification of its target gene EphA2 in pituitary tissues in Yanbian cattle

Bao Yuan, Wang‑Yang Yu, Li‑Sheng Dai, Yan Gao, Yu Ding, Xian‑Feng Yu, Jian Chen, Jia‑Bao Zhang

Pages: 5753-5761 Published online on: 06 August 2015
Open Access

Low expression of DLC1 is predictive of poor therapeutic efficiency of fluoropyrimidine and oxaliplatin as adjuvant chemotherapy in gastric cancer

Yuqi Su, Li Lin, Jingwen Zhang, Yaqi Jiang, Changqie Pan, Li Sun, Jiangman Duan, Wangjun Liao

Pages: 5771-5779 Published online on: 03 August 2015
Open Access

MicroRNA‑19a mediates gastric carcinoma cell proliferation through the activation of nuclear factor‑κB

Fan Yang, Hongjian Wang, Zhenyu Jiang, Anxiang Hu, Lisha Chu, Yiling Sun, Junqing Han

Pages: 5780-5786 Published online on: 29 July 2015
Open Access

Molecular docking to explore the possible binding mode of potential inhibitors of thioredoxin glutathione reductase

Jingwei Huang, Weijuan Hua, Jiahuang Li, Zichun Hua

Pages: 5787-5795 Published online on: 27 July 2015
Open Access

Histopathology of melanosis coli and determination of its associated genes by comparative analysis of expression microarrays

Xiao‑Αn Li, Yan Zhou, Shu‑Χian Zhou, Hai‑Rong Liu, Jin‑Mei Xu, Long Gao, Xian‑Jing Yu, Xiao‑Hui Li

Pages: 5807-5815 Published online on: 27 July 2015
Open Access

Ponicidin suppresses HT29 cell growth via the induction of G1 cell cycle arrest and apoptosis

Jie Du, Chunyou Chen, Yiqun Sun, Lin Zheng, Wanchen Wang

Pages: 5816-5820 Published online on: 29 July 2015
Open Access

Activated farnesoid X receptor attenuates apoptosis and liver injury in autoimmune hepatitis

Fan Lian, Yu Wang, Youjun Xiao, Xiwen Wu, Hanshi Xu, Liuqin Liang, Xiuyan Yang

Pages: 5821-5827 Published online on: 31 July 2015
Open Access

Silica promotes the transdifferentiation of rat circulating fibrocytes in vitro

Wu Yao, Suna Liu, Ju Li, Changfu Hao

Pages: 5828-5836 Published online on: 11 August 2015
Open Access

Polyphenolic composition of grape stem extracts affects antioxidant activity in endothelial and muscle cells

Nikolaos Goutzourelas, Dimitrios Stagos, Ypatios Spanidis, Maria Liosi, Anna Apostolou, Alexandros Priftis, Serko Haroutounian, Demetrios A. Spandidos, Aristidis M. Tsatsakis, Demetrios Kouretas

Pages: 5846-5856 Published online on: 12 August 2015

Rose myrtle (Rhodomyrtus tomentosa) extract and its component, piceatannol, enhance the activity of DNA polymerase and suppress the inflammatory response elicited by UVB‑induced DNA damage in skin cells

Sawako Shiratake, Tatsuo Nakahara, Hiroyasu Iwahashi, Takefumi Onodera, Yoshiyuki Mizushina

Pages: 5857-5864 Published online on: 30 July 2015

Roles of heat shock factor 1 in isoproterenol‑induced myocardial fibrosis in mice

Yong Xie, Lihua Zhang, Bin Zhang, Li Fang

Pages: 5872-5878 Published online on: 30 July 2015

Optimal compressive force accelerates osteoclastogenesis in RAW264.7 cells

Takako Hayakawa, Yoshitaka Yoshimura, Takashi Kikuiri, Mino Matsuno, Tomokazu Hasegawa, Kumu Fukushima, Kenjiro Shibata, Yoshiaki Deyama, Kuniaki Suzuki, Junichiro Iida

Pages: 5879-5885 Published online on: 29 July 2015

A genome-wide study of DNA methylation modified by epigallocatechin-3-gallate in the CAL-27 cell line

Li‑Li Chen, Wen‑Fei Han, Ying Geng, Jian‑Sheng Su

Pages: 5886-5890 Published online on: 27 July 2015

Gremlin 2 inhibits adipocyte differentiation through activation of Wnt/β-catenin signaling

Qing Wu, Shi-Guo Tang, Zhong‑Ming Yuan

Pages: 5891-5896 Published online on: 27 July 2015

Tectonic 1 accelerates gastric cancer cell proliferation and cell cycle progression in vitro

Xinbao Wang, Qiming Yu, Yingli Zhang, Zhiqiang Ling, Pengfei Yu

Pages: 5897-5902 Published online on: 05 August 2015

Simvastatin promotes alveolar epithelial cell proliferation and attenuates cigarette smoke‑induced emphysema in rats

Shuyue Xia, Jian Kang, Yanduo Jiang, Desheng Huang, Shi Wang, Baosen Pang

Pages: 5903-5910 Published online on: 03 August 2015

Inactivation of INK4a and ARF induces myocardial proliferation and improves cardiac repair following ischemia‑reperfusion

Songtao An, Yan Chen, Chuanyu Gao, Bingyu Qin, Xianhui Du, Fanmin Meng, Yanyan Qi

Pages: 5911-5916 Published online on: 29 July 2015

Epirubicin inhibits growth and alters the malignant phenotype of the U‑87 glioma cell line

Xiao‑Feng Wang, Zhe‑Feng Zhao, Ming‑Hui Chen, Qing‑Hua Yuan, Yong‑Li Li, Chuan‑Lu Jiang

Pages: 5917-5923 Published online on: 12 August 2015

Combination of L-gossypol and low-concentration doxorubicin induces apoptosis in human synovial sarcoma cells

Xilin Baoleri, Chao Dong, Yang Zhou, Zhaojun Zhang, Xueliang Lu, Pengming Xie, Yongqi Li

Pages: 5924-5932 Published online on: 28 July 2015

Effect of transplanted adipose‑derived stem cells in mice exhibiting idiopathic pulmonary fibrosis

Hongbin Jiang, Jun Zhang, Zhemin Zhang, Shengxiang Ren, Chuansen Zhang

Pages: 5933-5938 Published online on: 05 August 2015

Phenethyl isothiocyanate enhances adriamycin‑induced apoptosis in osteosarcoma cells

Qie Fan, Xinli Zhan, Zengming Xiao, Chong Liu

Pages: 5945-5950 Published online on: 05 August 2015

Effect of CoCl2 on fracture repair in a rat model of bone fracture

Jiang Huang, Liming Liu, Mingli Feng, Shuai An, Meng Zhou, Zheng Li, Jiajian Qi, Huiliang Shen

Pages: 5951-5956 Published online on: 27 July 2015

Gua Lou Gui Zhi decoction attenuates post‑stroke spasticity via the modulation of GABAB receptors

Xiaoqin Zhu, Haixia Hu, Zuanfang Li, Ruhui Lin, Jingjie Mao, Lidian Chen

Pages: 5957-5962 Published online on: 11 August 2015

Determination of ABO blood group genotypes using the real‑time loop‑mediated isothermal amplification method

Chao Zhang, Juanli Zhu, Jiangcun Yang, Yinsheng Wan, Ting Ma, Yali Cui

Pages: 5963-5966 Published online on: 29 July 2015

Catabolite control protein A has an important role in the metabolic regulation of Streptococcus suis type 2 according to iTRAQ-based quantitative proteomic analysis

Xulong Lang, Zhonghai Wan, Ying Pan, Zhaoyang Bu, Xiuran Wang, Xiaoxu Wang, Xue Ji, Lingwei Zhu, Jiayu Wan, Yang Sun, Xinglong Wang

Pages: 5967-5972 Published online on: 11 August 2015

Zinc deficiency during in vitro maturation of porcine oocytes causes meiotic block and developmental failure

Yubyeol Jeon, Junchul David Yoon, Lian Cai, Seon‑Ung Hwang, Eunhye Kim, Zhong Zheng, Euibae Jeung, Eunsong Lee, Sang‑Hwan Hyun

Pages: 5973-5982 Published online on: 27 July 2015

Molecular screening of the LPCAT1 gene in patients with retinitis pigmentosa without defined mutations in known retinitis pigmentosa genes

Juan Wu, Hong‑Ting Wang, Xiu‑Feng Huang, Xin‑Lan Lei, Qin‑Kang Lu, Zi‑Bing Jin

Pages: 5983-5988 Published online on: 10 August 2015

Characterization of fluorescent NBD‑cholesterol efflux in thp‑1‑derived macrophages

Wei Song, Wei Wang, Yu Wang, Liyang Dou, Lianfeng Chen, Xiaowei Yan

Pages: 5989-5996 Published online on: 30 July 2015

High‑mobility group box 1 has a prognostic role and contributes to epithelial mesenchymal transition in human hepatocellular carcinoma

Zhikui Liu, Changwei Dou, Yufeng Wang, Yuli Jia, Qing Li, Xin Zheng, Yingmin Yao, Qingguang Liu, Tao Song

Pages: 5997-6004 Published online on: 05 August 2015

Elastic large muscular vessel wall engineered with bone marrow‑derived cells under pulsatile stimulation in a bioreactor

Zhi Cheng Xu, Qun Zhang, Hong Li

Pages: 6005-6012 Published online on: 29 July 2015

Inhibition of microRNA‑155 relieves sepsis‑induced liver injury through inactivating the JAK/STAT pathway

Xin Lv, Yucai Zhang, Yun Cui, Yuqian Ren, Rui Li, Qunfang Rong

Pages: 6013-6018 Published online on: 05 August 2015

Distribution and effect of steroidal saponin derivative WRC3 in B16 melanoma cells

Zeliang Wei, Yuyan Liang, Limei Ma, Ke Li, Hai Niu, Wen Huang

Pages: 6019-6024 Published online on: 12 August 2015

Expression of protein kinase C isoforms in cultured human tenon's capsule fibroblast cells

Ping Ma, Qianying Gao, Zhichong Wang, Keming Yu

Pages: 6025-6030 Published online on: 10 August 2015

Epigallocatechin‑3‑gallate inhibits the invasion of salivary adenoid cystic carcinoma cells by reversing the hypermethylation status of the RECK gene

Xiao‑Qing Zhou, Xiao‑Nan Xu, Lei Li, Jian‑Jun Ma, En‑Ming Zhen, Cheng‑Bing Han

Pages: 6031-6036 Published online on: 11 August 2015

K604, a specific acyl‑CoA:cholesterol acyltransferase 1 inhibitor, suppresses proliferation of U251‑MG glioblastoma cells

Takuji Ohmoto, Kazuchika Nishitsuji, Nobuyuki Yoshitani, Makoto Mizuguchi, Yuto Yanagisawa, Hiroyuki Saito, Naomi Sakashita

Pages: 6037-6042 Published online on: 07 August 2015

Inhibition of microRNA‑30a prevents puromycin aminonucleoside‑induced podocytic apoptosis by upregulating the glucocorticoid receptor α

Hua Xie, Hong‑Li Lin, Nan Wang, Yan‑Ling Sun, Yu Kan, Hui Guo, Ji‑Lin Chen, Ming Fang

Pages: 6043-6052 Published online on: 14 August 2015

SHSST‑cyclodextrin complex inhibits TGF‑β/Smad3/CTGF to a greater extent than silymarin in a rat model of carbon tetrachloride‑induced liver injury

Cheng‑Hsun Yang, Wei‑Jen Ting, Chia‑Yao Shen, His‑Hsien Hsu, Yueh‑Min Lin, Sheng-Huang Chang, Fuu‑Jen Tsai, Viswanadha Vijaya Padma, Chih‑Yang Huang, Yuhsin Tsai

Pages: 6053-6059 Published online on: 06 August 2015

Small nuclear ribonucleoprotein associated polypeptide N accelerates cell proliferation in pancreatic adenocarcinoma

Jin Ma, Zhuo Zhang, Jiancheng Wang

Pages: 6060-6064 Published online on: 11 August 2015

Effect of transcatheter arterial chemoembolization on cellular immune function and regulatory T cells in patients with hepatocellular carcinoma

Juan Liao, Jiangwei Xiao, Yunfeng Zhou, Zilin Liu, Chunhui Wang

Pages: 6065-6071 Published online on: 03 August 2015

DAL‑1/4.1B contributes to epithelial‑mesenchymal transition via regulation of transforming growth factor‑β in lung cancer cell lines

Feng Yu, Hua Yang, Zhanmin Zhang, Zhijun Wang, Jianping Xiong

Pages: 6072-6078 Published online on: 12 August 2015

Activation of Toll-like receptor 7 inhibits the proliferation and migration, and induces the apoptosis of pancreatic cancer cells

Bing‑Bing Zou, Fang Wang, Lei Li, Feng‑Wei Cheng, Rui Jin, Xin Luo, Li‑Xin Zhu, Xiaoping Geng, Sheng‑Quan Zhang

Pages: 6079-6085 Published online on: 28 July 2015

Vitamin C attenuates the toxic effect of aristolochic acid on renal tubular cells via decreasing oxidative stress‑mediated cell death pathways

Tsai‑Kun Wu, Chyou‑Wei Wei, Ying‑Ru Pan, Shur‑Hueih Cherng, Wei‑Jung Chang, Hsueh‑Fang Wang, Yung‑Luen Yu

Pages: 6086-6092 Published online on: 03 August 2015

Effect of thymosin α1 on the phenotypic and functional maturation of dendritic cells from children with acute lymphoblastic leukemia

Xuerong Li, Xiaodan Liu, Yanxia Zhao, Ren Zhong, Aiqin Song, Lirong Sun

Pages: 6093-6097 Published online on: 30 July 2015

Association between liver X receptor‑α and neuron‑derived orphan nuclear receptor‑1 in Kupffer cells of C57BL/6 mice during inflammation

Kun He, Zhuo‑Ya Dai, Pei‑Zhi Li, Xi‑Wen Zhu, Jian‑Ping Gong

Pages: 6098-6104 Published online on: 30 July 2015

Clinical correlation of peripheral CD4+‑cell sub‑sets, their imbalance and Parkinson's disease

Yuhua Chen, Benquan Qi, Wenfang Xu, Bo Ma, Li Li, Qiming Chen, Weidong Qian, Xiaolin Liu, Hongdang Qu

Pages: 6105-6111 Published online on: 29 July 2015

Fenofibrate suppresses cellular metabolic memory of high glucose in diabetic retinopathy via a sirtuin 1-dependent signalling pathway

Shuzhi Zhao, Jun Li, Na Wang, Bingqing Zheng, Tao Li, Qing Gu, Xun Xu, Zhi Zheng

Pages: 6112-6118 Published online on: 31 July 2015

Probiotics modify human intestinal mucosa-associated microbiota in patients with colorectal cancer

Zhiguang Gao, Bomin Guo, Renyuan Gao, Qingchao Zhu, Wen Wu, Huanlong Qin

Pages: 6119-6127 Published online on: 27 July 2015

Two‑gene mutation in a single patient: Biochemical and functional analysis for a correct interpretation of exome results

Anna Monica Bianco, Flavio Faletra, Diego Vozzi, Martina Girardelli, Alessandra Knowles, Alberto Tommasini, Giorgio Zauli, Annalisa Marcuzzi

Pages: 6128-6132 Published online on: 11 August 2015

Resveratrol inhibits oligomeric Aβ‑induced microglial activation via NADPH oxidase

Yao Yao, Juan Li, Yang Niu, Jian‑Qiang Yu, Ling Yan, Zhen‑Hua Miao, Xun‑Xia Zhao, Yuan‑Jie Li, Wan‑Xia Yao, Ping Zheng, Wei‑Qi Li

Pages: 6133-6139 Published online on: 07 August 2015

Hepatoma‑derived growth factor‑2 is highly expressed during development and in spinal cord injury

Zerui Zhuang, Guolong Mei, Weidong Liu, Yuchun Chen, Jican Zeng, Wei Zhang, Guanfeng Yao, Xinjia Wang

Pages: 6140-6144 Published online on: 06 August 2015

MEN1 c.825‑1G>A mutation in a family with multiple endocrine neoplasia type 1: A case report

Zhiwei Ning, Ou Wang, Xunwu Meng, Xiaoping Xing, Weibo Xia, Yan Jiang, Mei Li, Yuan Xu

Pages: 6152-6156 Published online on: 29 July 2015

Effect of quantum dots on the biological behavior of the EJ human bladder urothelial carcinoma cell line

Run Yuan, Wei‑Min Yu, Fan Cheng, Xiao‑Bin Zhang, Yuan Ruan, Zhi‑Xiu Cao, Stéphane Larré

Pages: 6157-6163 Published online on: 03 August 2015

Upregulation of the gene expression of CLOCK is correlated with hypoxia‑inducible factor 1α in advanced varicose lesions

Xiao Tang, Daqiao Guo, Changpo Lin, Zhenyu Shi, Ruizhe Qian, Weiguo Fu, Jianjun Liu, Xu Li, Longhua Fan

Pages: 6164-6170 Published online on: 12 August 2015

Effect of FTY720-phosphate on the expression of inflammation-associated molecules in astrocytes in vitro

Stefanie Janssen, Caroline Schlegel, Viktoria Gudi, Chittappen Kandiyil Prajeeth, Thomas Skripuletz, Corinna Trebst, Martin Stangel

Pages: 6171-6177 Published online on: 27 July 2015

MicroRNA‑29a inhibits mesenchymal stem cell viability and proliferation by targeting Roundabout 1

Yudong Zhang, Shenghua Zhou

Pages: 6178-6184 Published online on: 05 August 2015

MicroRNA‑210 is upregulated by hypoxia-inducible factor‑1α in the stromal cells of giant cell tumors of bone

Shibing Guo, Rui Bai, Wanlin Liu, Aiqing Zhao, Zhenqun Zhao, Yuxin Wang, Yong Wang, Wei Zhao, Wenxuan Wang

Pages: 6185-6192 Published online on: 03 August 2015

MicroRNA-145 inhibits migration and invasion via inhibition of fascin 1 protein expression in non-small-cell lung cancer cells

Yingying Zhang, Xucheng Yang, Haijun Wu, Weibin Zhou, Zhenzhen Liu

Pages: 6193-6198 Published online on: 31 July 2015

An insertion/deletion polymorphism at the microRNA-122 binding site in the interleukin-1α 3'-untranslated region is associated with a risk for osteoarthritis

Fan Yang, Anfeng Hu, Dewei Zhao, Lin Guo, Lei Yang, Benjie Wang, Fengde Tian, Baoyi Liu, Shibo Huang, Hui Xie

Pages: 6199-6206 Published online on: 27 July 2015

Raloxifene neutralizes the adverse effects of glutamate on cultured neurons by regulation of calcium oscillations

Xiangyu Zhou, Zhendong Yang, Li Han, Xiaoyong Li, Meina Feng, Teng Zhang, Hongbin Luo, Liping Zhu, Jiwei Zhang, Qi Zhang, Qinghua Hu

Pages: 6207-6214 Published online on: 06 August 2015

Hochu‑ekki‑to (Bu‑zhong‑yi‑qi‑tang), a herbal medicine, enhances cisplatin‑induced apoptosis in HeLa cells

Tetsuo Sato, Kazuko Kita, Chihomi Sato, Atsushi Kaneda

Pages: 6215-6220 Published online on: 29 July 2015

Activation of protease‑activated receptor‑2 is associated with increased expression of inflammatory factors in the adipose tissues of obese mice

Mengmeng Li, Xiaoming Yang, Yadong Zhang, Liang Chen, Hanyu Lu, Xiaobo Li, Lianhua Yin, Xiuling Zhi

Pages: 6227-6234 Published online on: 05 August 2015

MicroRNA‑133a and microRNA‑326 co‑contribute to hepatocellular carcinoma 5‑fluorouracil and cisplatin sensitivity by directly targeting B‑cell lymphoma‑extra large

Jin Ma, Ting Wang, Rui Guo, Xiaoyan Yang, Jie Yin, Jia Yu, Qiong Xiang, Xia Pan, Xuyu Zu, Cuiying Peng, Huifang Tang, Xiaoyong Lei

Pages: 6235-6240 Published online on: 29 July 2015

Proinflammatory effects of the hemagglutinin protein of the avian influenza A (H7N9) virus and microRNA‑mediated homeostasis response in THP‑1 cells

Shaobo Zhang, Dayong Gu, Xiaoxi Ouyang, Weidong Xie

Pages: 6241-6246 Published online on: 29 July 2015

MicroRNA‑128a, BMI1 polycomb ring finger oncogene, and reactive oxygen species inhibit the growth of U‑87 MG glioblastoma cells following exposure to X‑ray radiation

Lan Ye, Guanying Yu, Cuihong Wang, Bin Du, Dianshui Sun, Junli Liu, Tonggang Qi, Xiaoming Yu, Wei Wei, Jian Cheng, Yuhua Jiang

Pages: 6247-6254 Published online on: 04 August 2015

Peroxisome proliferator‑activated receptor‑γ inhibits pancreatic cancer cell invasion and metastasis via regulating MMP‑2 expression through PTEN

Yue Li, Da‑Wei Zhang, Dian‑Qiang Lin, Liang‑Qi Cao

Pages: 6255-6260 Published online on: 12 August 2015

miR‑214 promotes osteosarcoma tumor growth and metastasis by decreasing the expression of PTEN

Chun‑Jie Liu, Kun‑Lun Yu, Guo‑Li Liu, De‑Hu Tian

Pages: 6261-6266 Published online on: 06 August 2015

Mutation analysis of CACNA1S and SCN4A in patients with hypokalemic periodic paralysis

Xiao‑Ying Wang, Bing‑Wen Ren, Zeng‑Hua Yong, Hong‑Yan Xu, Qiu‑Xia Fu, He‑Bin Yao

Pages: 6267-6274 Published online on: 07 August 2015

Promoter methylation, mRNA expression of goat tumor‑associated genes and mRNA expression of DNA methyltransferase in enzootic nasal tumors

Zifang Quan, Ni Ye, Zhongxiang Hao, Caifang Wen, Hong Liao, Manli Zhang, Lu Luo, Sanjie Cao, Xintian Wen, Rui Wu, Qigui Yan

Pages: 6275-6285 Published online on: 05 August 2015

MicroRNA‑214 promotes proliferation and inhibits apoptosis via targeting Bax in nasopharyngeal carcinoma cells

Jian He, Yaoyun Tang, Yongquan Tian

Pages: 6286-6292 Published online on: 03 August 2015

Cytotoxic and apoptogenic effects of Strobilanthes crispa Blume extracts on nasopharyngeal cancer cells

Rhun Yian Koh, Yi Chi Sim, Hwee Jin Toh, Liang Kuan Liam, Rachael Sze Lynn Ong, Mei Yeng Yew, Yee Lian Tiong, Anna Pick Kiong Ling, Soi Moi Chye, Khuen Yen Ng

Pages: 6293-6299 Published online on: 30 July 2015

Momordica cochinchinensis Spreng. seed extract suppresses breast cancer growth by inducing cell cycle arrest and apoptosis

Lei Zheng, Yanmin Zhang, Yanping Liu, Xiaoyan Ou Yang, Yingzhuan Zhan

Pages: 6300-6310 Published online on: 05 August 2015

Immunological characterization and verification of recombinant streptococcal protein G

Hucheng Zhang, Weifeng Liang, Haitao Fan, Jun Yang, Guowei Yang, Xiaojie Wang, Liang Chen, Tao Liang

Pages: 6311-6315 Published online on: 31 July 2015

Small interfering RNA-induced silencing of galectin-3 inhibits the malignant phenotypes of osteosarcoma in vitro

Pengfei Lei, Hongbo He, Yihe Hu, Zhan Liao

Pages: 6316-6322 Published online on: 31 July 2015

A comparative study of acellular nerve xenografts and allografts in repairing rat facial nerve defects

Haitao Huang, Hongxi Xiao, Huawei Liu, Yu Niu, Rongzeng Yan, Min Hu

Pages: 6330-6336 Published online on: 27 July 2015

16S rDNA PCR-DGGE and sequencing in the diagnosis of neonatal late-onset septicemia

Dong Liu, Lizhong Du, Jialin Yu, Luquan Li, Qing Ai, Jinxing Feng, Chao Song

Pages: 6346-6352 Published online on: 28 July 2015

Oxidative stress biomarkers and paraoxonase 1 polymorphism frequency in farmers occupationally exposed to pesticides

Chiara Costa, Silvia Gangemi, Federica Giambò, Venerando Rapisarda, Daniela Caccamo, Concettina Fenga

Pages: 6353-6357 Published online on: 06 August 2015

Oncolytic adenovirus‑mediated mda‑7/IL‑24 expression suppresses osteosarcoma growth and enhances sensitivity to doxorubicin

Zongming Liu, Libo Xu, Hongping Yuan, Yang Zhang, Xiaona Zhang, Dongxu Zhao

Pages: 6358-6364 Published online on: 05 August 2015

Involvement of an intracellular vesicular transport process in naked-sgRNA-mediated TRUE gene silencing

Masato Tamura, Mitsuoki Kawano, Mari Sato, Masayuki Nashimoto

Pages: 6365-6369 Published online on: 31 July 2015

Effects of Dangkwisoo‑san, a traditional herbal medicine for treating pain and blood stagnation, on the pacemaker activities of cultured interstitial cells of Cajal

Soon‑Ki Sung, Sung Jin Kim, Tae Seok Ahn, Noo Ri Hong, Hyun Soo Park, Young Kyu Kwon, Byung Joo Kim

Pages: 6370-6376 Published online on: 10 August 2015

Baicalin alleviates diabetes‑associated cognitive deficits via modulation of mitogen-activated protein kinase signaling, brain‑derived neurotrophic factor and apoptosis

Ping Ma, Xiao‑Yuan Mao, Xiao‑Lei Li, Ying Ma, Yuan‑Dong Qiao, Zhao‑Qian Liu, Hong‑Hao Zhou, Yong‑Gang Cao

Pages: 6377-6383 Published online on: 12 August 2015

Metformin suppresses intrahepatic coagulation activation in mice with lipopolysaccharide/D‑galactosamine‑induced fulminant hepatitis

Xianqiong Gong, Rui Duan, Jin‑E Ao, Qing Ai, Pu Ge, Ling Lin, Li Zhang

Pages: 6384-6390 Published online on: 10 August 2015
Journal Cover

October 2015
Volume 12 Issue 4

Print ISSN: 1791-2997
Online ISSN: 1791-3004

2014 Impact Factor: 1.554
Ranked #48/123 Medicine Research and Experimental
(total number of cites)

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