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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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November-December 2014 Volume 2 Issue 6

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International Journal of Molecular Medicine

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Case Report

Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report

  • Authors:
    • Xianhong Xiang
    • Xiaoyan Wang
    • Qinqin Yi
    • Lin Lin
    • Xiangsong Zhang
    • Hong Liang
    • Jianyong Yang

  • View Affiliations / Copyright

    Affiliations: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat‑Sen University, Guangzhou, Guangdong 510080, P.R. China, Department of Nuclear Medicine, The First Affiliated Hospital, Sun Yat‑Sen University, Guangzhou, Guangdong 510080, P.R. China
  • Pages: 945-948
    |
    Published online on: July 11, 2014
       https://doi.org/10.3892/mco.2014.347
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Abstract

Precursor T‑cell lymphoblastic lymphoma (T‑LBL) is a rare type of malignant lymphoma, with clinical manifestations including diaphragmatic lymph node enlargement, accompanied by local oppression and/or systemic lymphoma symptoms. However, extensive involvement of the mediastinum, pleura and pericardium is rare in T‑LBL cases. This is the case report of a T‑LBL extensively involving the mediastinum, pleura and pericardium in a 54‑year‑old woman. The patient complained of anhelation, chest tightness and tiredness for ~3 months. A computed tomography (CT) scan of the chest revealed a diffuse mass of soft tissue density involving the mediastinum, pleura and pericardium. Several thoracocenteses indicated inflammatory changes and cytological examination of the pleural fluid and pleural biopsy under CT guidance identified no heterotypic cells. As 18F‑fluorodeoxyglucose (FDG) positron emission tomography (PET)̸CT imaging revealed a diffused moderate FDG uptake (maximum standard uptake value of 4) by the mediastinum, pleura and cardiac sac, we diagnosed a malignant lymphoma. We subsequently successfully performed needle biopsy under PET/CT guidance according to the PET/CT images and the diagnosis of T‑LBL was pathologically confirmed.
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Copy and paste a formatted citation
Spandidos Publications style
Xiang X, Wang X, Yi Q, Lin L, Zhang X, Liang H and Yang J: Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report. Mol Clin Oncol 2: 945-948, 2014.
APA
Xiang, X., Wang, X., Yi, Q., Lin, L., Zhang, X., Liang, H., & Yang, J. (2014). Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report. Molecular and Clinical Oncology, 2, 945-948. https://doi.org/10.3892/mco.2014.347
MLA
Xiang, X., Wang, X., Yi, Q., Lin, L., Zhang, X., Liang, H., Yang, J."Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report". Molecular and Clinical Oncology 2.6 (2014): 945-948.
Chicago
Xiang, X., Wang, X., Yi, Q., Lin, L., Zhang, X., Liang, H., Yang, J."Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report". Molecular and Clinical Oncology 2, no. 6 (2014): 945-948. https://doi.org/10.3892/mco.2014.347
Copy and paste a formatted citation
x
Spandidos Publications style
Xiang X, Wang X, Yi Q, Lin L, Zhang X, Liang H and Yang J: Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report. Mol Clin Oncol 2: 945-948, 2014.
APA
Xiang, X., Wang, X., Yi, Q., Lin, L., Zhang, X., Liang, H., & Yang, J. (2014). Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report. Molecular and Clinical Oncology, 2, 945-948. https://doi.org/10.3892/mco.2014.347
MLA
Xiang, X., Wang, X., Yi, Q., Lin, L., Zhang, X., Liang, H., Yang, J."Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report". Molecular and Clinical Oncology 2.6 (2014): 945-948.
Chicago
Xiang, X., Wang, X., Yi, Q., Lin, L., Zhang, X., Liang, H., Yang, J."Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report". Molecular and Clinical Oncology 2, no. 6 (2014): 945-948. https://doi.org/10.3892/mco.2014.347
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