Journal Articles

Open Access

MicroRNA‑665 regulates the proliferation, apoptosis and adhesion of gastric cancer cells by binding to cadherin 3

Xinhui Fang, Yangqiu Bai, Lida Zhang, Songze Ding

Article Number: 494 Published online on: 26 April 2021
Open Access

HOXA11‑AS induces cisplatin resistance by modulating the microRNA‑98/PBX3 axis in nasopharyngeal carcinoma

Haineng Li, Jia Huang, Sa Yu, Hangbo Li, Yan Zhou, Qingwei Wu

Article Number: 493 Published online on: 26 April 2021
Open Access

Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis

Sung-Hyun Kim, Gang-Sik Choo, Eun-Seon Yoo, Joong-Seok Woo, Jae-Han Lee, So-Hee Han, Soo-Hyun Jung, Hyeong-Jin Kim, Ji-Youn Jung

Article Number: 492 Published online on: 26 April 2021
Open Access

Expression pattern of histone lysine‑specific demethylase 6B in gastric cancer

Shujun Wang, Yiping Wang, Hui Zhu, Miaohui Chen, Liang Zhang

Article Number: 491 Published online on: 26 April 2021
Open Access

Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer

Tomoya Kato, Mikihito Nakamori, Shuichi Matsumura, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue

Article Number: 490 Published online on: 23 April 2021
Open Access

The effectiveness of plasma miR‑33a‑5p as a predictive biomarker for the efficacy of colorectal cancer chemotherapy

Megumi Sasaki, Toshiaki Ishikawa, Megumi Ishiguro, Satoshi Okazaki, Shinichi Yamauchi, Akifumi Kikuchi, Takatoshi Matsuyama, Kenro Kawada, Masanori Tokunaga, Hiroyuki Uetake, Yusuke Kinugasa

Article Number: 489 Published online on: 22 April 2021
Open Access

Upregulation of glucosamine‑phosphate N‑acetyltransferase 1 is a promising diagnostic and predictive indicator for poor survival in patients with lung adenocarcinoma

Pengyuan Zhu, Shaorui Gu, Haitao Huang, Chongjun Zhong, Zhenchuan Liu, Xin Zhang, Wenli Wang, Shiliang Xie, Kaiqin Wu, Tiancheng Lu, Yongxin Zhou

Article Number: 488 Published online on: 22 April 2021
Open Access

Predictive effects of preoperative serum CA125 and AFP levels on post‑hepatectomy survival in patients with hepatitis B‑related hepatocellular carcinoma

Chuang Qin, Yan Gao, Jiangfa Li, Chao Huang, Songqing He

Article Number: 487 Published online on: 22 April 2021
Open Access

Circular RNA UBAP2 promotes the proliferation of prostate cancer cells via the miR‑1244/MAP3K2 axis

Xiaodong Li, Baihetiya Azhati, Wenguang Wang, Mulati Rexiati, Chen Xing, Yujie Wang

Article Number: 486 Published online on: 21 April 2021
Open Access

SPARC promotes pancreatic cancer cell proliferation and migration through autocrine secretion into the extracellular milieu

Kehua Pan, Xince Huang, Xiufen Jia

Article Number: 485 Published online on: 21 April 2021
Open Access

Krüppel‑like factor 5 is upregulated and induces cell proliferation in endometrial cancer

Tetsuya Moritake, Junya Kojima, Kaiyu Kubota, Fumitoshi Terauchi, Keiichi Isaka, Hirotaka Nishi

Article Number: 484 Published online on: 21 April 2021
Open Access

GAD1 expression and its methylation as indicators of malignant behavior in thymic epithelial tumors

Shiho Soejima, Kazuya Kondo, Mitsuhiro Tsuboi, Kyoka Muguruma, Bilguun Tegshee, Yukikiyo Kawakami, Koichiro Kajiura, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku

Article Number: 483 Published online on: 21 April 2021
Open Access

MicroRNA‑204 plays a role as a tumor suppressor in Newcastle disease virus‑induced oncolysis in lung cancer A549 cells

Ying Liang, Wen-Yu Tian, Juan-Juan Huang, Ling-Xi Gao, Xiao-Hui Fan

Article Number: 482 Published online on: 21 April 2021

miR‑188‑5p promotes oxaliplatin resistance by targeting RASA1 in colon cancer cells

Xijia Zhu, Xishun Luo, Zhike Song, Shiyu Jiang, Xiangkai Long, Xueyuan Gao, Xinyang Xie, Laijian Zheng, Haipeng Wang

Article Number: 481 Published online on: 20 April 2021
Open Access

[Corrigendum] Chemopreventive effect of 4'‑hydroxychalcone on intestinal tumorigenesis in ApcMin mice

Qing Chen, Jiahong Lei, Jinzhe Zhou, Shaoze Ma, Qi Huang, Bujun Ge

Article Number: 480 Published online on: 20 April 2021
Open Access

Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis

Mehtap Kilic Eren, Nur Betül Kartal, Hatice Pi̇levneli̇

Article Number: 479 Published online on: 19 April 2021
Open Access

Low CFB expression is independently associated with poor overall and disease‑free survival in patients with lung adenocarcinoma

Chenglu He, Ya Li, Ruixian Zhang, Jing Chen, Xingxing Feng, Yong Duan

Article Number: 478 Published online on: 19 April 2021
Open Access

Incaspitolide A isolated from Carpesium cernuum L. inhibits the growth of prostate cancer cells and induces apoptosis via regulation of the PI3K/Akt/xIAP pathway

Yuanshe Huang, Jingxin Mao, Lai Zhang, Hongwei Guo, Chen Yan, Min Chen

Article Number: 477 Published online on: 19 April 2021
Open Access

Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis

Xuemei Huang, Chunfeng Liang, Haiyan Yang, Xin Li, Xiujun Deng, Xinghuan Liang, Li Li, Zhenxing Huang, Decheng Lu, Yan Ma, Zuojie Luo

Article Number: 476 Published online on: 15 April 2021
Open Access

Analysis of the association between KIN17 expression and the clinical features/prognosis of epithelial ovarian cancer, and the effects of KIN17 in SKOV3 cells

Junyu Chen, Yang Xia, Yuanqing Peng, Shan Wu, Wei Liu, Haoxian Zhang, Tian Wang, Zhaoyun Yang, Shuhua Zhao, Lijing Zhao

Article Number: 475 Published online on: 15 April 2021
Open Access

MicroRNA‑1226‑3p has a tumor‑promoting role in osteosarcoma

Yong Li, Dai Song, Ting An, Jie Liu, Qian Yang, Shaokui Nan

Article Number: 474 Published online on: 15 April 2021
Open Access

Novel brd4 inhibitors with a unique scaffold exhibit antitumor effects

Young Hun Kim, Minsung Kim, Ji Eun Kim, Miyoun Yoo, Heung Kyoung Lee, Chong Ock Lee, Minjin Yoo, Kwan-Young Jung, Yeongrin Kim, Sang Un Choi, Chi Hoon Park

Article Number: 473 Published online on: 14 April 2021
Open Access

Long non‑coding RNA SNHG17 enhances the aggressiveness of C4‑2 human prostate cancer cells in association with β‑catenin signaling

Haijun Zhao, Haijing Dong, Peng Wang, Hai Zhu

Article Number: 472 Published online on: 13 April 2021
Open Access

lncRNA PCAT6 facilitates cell proliferation and invasion via regulating the miR‑326/hnRNPA2B1 axis in liver cancer

Jun Luo, Jiaping Zheng, Weiyuan Hao, Hui Zeng, Zhewei Zhang, Guoliang Shao

Article Number: 471 Published online on: 13 April 2021
Open Access

LACTB and LC3 could serve as potential biomarkers of gastric cancer to neoadjuvant chemotherapy with oxaliplatin plus S‑1

Fang Yang, Zhiqiang Yan, Wei Nie, Zeying Liu, Xingzhen Cheng, Wei Wang, Chunyan Shao, Gui Fu, Yanni Yu

Article Number: 470 Published online on: 13 April 2021
Open Access

Effect of the circCDR1as/miR‑641/XIAP regulatory axis on the proliferation and invasion of the prostate cancer PC‑3 cell line

Yulin Niu, Jin Hua He, Yinglian Zhang, Kun Li, Chungen Xing

Article Number: 469 Published online on: 13 April 2021
Open Access

DNA methylation variations in familial female and male breast cancer

Edoardo Abeni, Ilaria Grossi, Eleonora Marchina, Arianna Coniglio, Paolo Incardona, Pietro Cavalli, Fausto Zorzi, Pier Luigi Chiodera, Carlo Terenzio Paties, Marialuisa Crosatti, Giuseppina De Petro, Alessandro Salvi

Article Number: 468 Published online on: 12 April 2021
Open Access

Current status of extended ‘D2 plus’ lymphadenectomy in advanced gastric cancer (Review)

Jing-Quan Li, Donglei He, Yue-Xiang Liang

Article Number: 467 Published online on: 12 April 2021

Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases

Akio Shiomi, Masatoshi Kusuhara, Takashi Sugino, Teiichi Sugiura, Keiichi Ohshima, Takeshi Nagashima, Kenichi Urakami, Masakuni Serizawa, Hideyuki Saya, Ken Yamaguchi

Article Number: 466 Published online on: 12 April 2021
Open Access

Regulatory function of peroxiredoxin I on 4‑(methylnitrosamino)‑1‑(3‑pyridyl)‑1‑butanone‑induced lung cancer development (Review)

Hu-Nan Sun, Chen-Xi Ren, Yi-Xi Gong, Dan-Ping Xie, Taeho Kwon

Article Number: 465 Published online on: 12 April 2021
Open Access

[Corrigendum] Ras‑related protein Rap2c promotes the migration and invasion of human osteosarcoma cells

Jinxia Wu, Wenqi Du, Xiucun Wang, Lulu Wei, Yaojie Pan, Xiaojin Wu, Jinling Zhang, Dongsheng Pei

Article Number: 462 Published online on: 12 April 2021
Open Access

PKM2 regulates proliferation and apoptosis through the Hippo pathway in oral tongue squamous cell carcinoma

Jia Luo, Lei Zhang, Lijuan Guo, Sen Yang

Article Number: 461 Published online on: 11 April 2021
Open Access

Role of aryl hydrocarbon receptor in central nervous system tumors: Biological and therapeutic implications (Review)

Montserrat Zaragoza‑Ojeda, Elisa Apatiga‑Vega, Francisco Arenas‑huertero

Article Number: 460 Published online on: 11 April 2021
Open Access

miR‑574‑5p mediates epithelial‑mesenchymal transition in small cell lung cancer by targeting vimentin via a competitive endogenous RNA network

Yanqin Sun, Yanmei Yi, Siyuan Gan, Ruifang Ye, Cailing Huang, Man Li, Jian Huang, Ying Guo

Article Number: 459 Published online on: 08 April 2021
Open Access

Inhibition of aquaporins as a potential adjunct to breast cancer cryotherapy

Haifa Alkhalifa, Fatima Mohammed, Sebastien Taurin, Khaled Greish, Safa Taha, Salim Fredericks

Article Number: 458 Published online on: 08 April 2021

MicroRNA‑133a‑3p suppresses malignant behavior of non‑small cell lung cancer cells by negatively regulating ERBB2

Yanhui Xu, Lei Zhang, Lilong Xia, Xinhai Zhu

Article Number: 457 Published online on: 08 April 2021
Open Access

Integrative analysis of the gastric cancer long non‑coding RNA‑associated competing endogenous RNA network

Yuyou Jiang, Xianqin Zhang, Li Rong, Yi Hou, Jing Song, Wanfeng Zhang, Min He, Yan Xie, Yue Li, Fangzhou Song

Article Number: 456 Published online on: 08 April 2021
Open Access

lncRNA HAR1B has potential to be a predictive marker for pazopanib therapy in patients with sarcoma

Hideharu Yamada, Masanobu Takahashi, Munenori Watanuki, Mika Watanabe, Sakura Hiraide, Ken Saijo, Keigo Komine, Chikashi Ishioka

Article Number: 455 Published online on: 08 April 2021
Open Access

Prognosis of patients treated in a single neurosurgical reference centre for brain metastasis caused by dormant disseminated cells

Lorenzo Ferlini, Lorenzo Peluso, Valentina Lolli, Nicolas Gaspard, Florence Lefranc

Article Number: 454 Published online on: 08 April 2021
Open Access

Daphnoretin induces reactive oxygen species‑mediated apoptosis in melanoma cells

Hui Wang, Xue Hu, Minjing Li, Zhaohai Pan, Defang Li, Qiusheng Zheng

Article Number: 453 Published online on: 08 April 2021

Ginsenoside Rg5 inhibits cancer cell migration by inhibiting the nuclear factor‑κB and erythropoietin‑producing hepatocellular receptor A2 signaling pathways

Leixin Song, Fan Yang, Zhengtao Wang, Li Yang, Yue Zhou

Article Number: 452 Published online on: 08 April 2021
Open Access

Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs (Review)

Zhangming Chen, Jie Hu, Songcheng Ying, Aman Xu

Article Number: 451 Published online on: 08 April 2021
Open Access

Excision repair cross‑complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence

Yen-Yun Wang, Pen-Tzu Fang, Chang-Wei Su, Yuk-Kwan Chen, Joh-Jong Huang, Ming-Yii Huang, Shyng-Shiou F. Yuan

Article Number: 450 Published online on: 07 April 2021
Open Access

Impact of copy number variant and single nucleotide polymorphism of the programmed death‑ligand 1 gene, programmed death‑ligand 1 protein expression and therapy regimens on overall survival in a large group of Caucasian patients with non‑small cell lung carcinoma

Anna Grenda, Paweł Krawczyk, Tomasz Kucharczyk, Justyna Błach, Katarzyna Reszka, Izabela Chmielewska, Jarosław Buczkowski, Robert Kieszko, Jan Siwiec, Tomasz Kubiatowski, Aleksandra Bożyk, Kinga Krukowska, Bożena Jarosz, Iwona Paśnik, Juliusz Pankowski, Daria Świniuch, Katarzyna Stencel, Michał Gil, Kinga Lew, Rodryg Ramlau, Aleksandra Szczęsna, Sebastian Fidler, Andrzej Sieracki, Andrzej Każarnowicz, Piotr Serwatowski, Tomasz Grodzki, Janusz Milanowski

Article Number: 449 Published online on: 07 April 2021

Impact of EGFR and EGFR ligand expression on treatment response in patients with metastatic colorectal cancer

Fee Klupp, Malte Sass, Frank Bergmann, Elias Khajeh, Omid Ghamarnejad, Matthias Hassenpflug, Arianeb Mehrabi, Yakup Kulu

Article Number: 448 Published online on: 07 April 2021
Open Access

Clinical value of lncRNA CCAT1 in serum extracellular vesicles as a potential biomarker for gastric cancer

Ke Xiao, Zhaogang Dong, Ding Wang, Min Liu, Juan Ding, Wendan Chen, Ziqi Shang, Congbo Yue, Yi Zhang

Article Number: 447 Published online on: 06 April 2021

Analysis of radiotherapy‑induced alteration of CD8+ T cells and PD‑L1 expression in patients with uterine cervical squamous cell carcinoma

Yasumasa Mori, Hiro Sato, Takuya Kumazawa, Tiara Bunga Mayang Permata, Yuya Yoshimoto, Kazutoshi Murata, Shin-Ei Noda, Takuya Kaminuma, Ken Ando, Takahiro Oike, Noriyuki Okonogi, Kohei Okada, Sangeeta Kakoti, Keiji Suzuki, Hayato Ikota, Hideaki Yokoo, Takashi Nakano, Tatsuya Ohno, Atsushi Shibata

Article Number: 446 Published online on: 06 April 2021
Open Access

Stromal expression of cancer‑associated fibroblast‑related molecules, versican and lumican, is strongly associated with worse relapse‑free and overall survival times in patients with esophageal squamous cell carcinoma

Naoto Yamauchi, Yasuyuki Kanke, Katsuharu Saito, Hirokazu Okayama, Shoki Yamada, Shotaro Nakajima, Eisei Endo, Koji Kase, Leo Yamada, Hiroshi Nakano, Takuro Matsumoto, Hiroyuki Hanayama, Yohei Watanabe, Suguru Hayase, Motonobu Saito, Zenichiro Saze, Kosaku Mimura, Tomoyuki Momma, Shinji Oki, Yuko Hashimoto, Koji Kono

Article Number: 445 Published online on: 06 April 2021
Open Access

Long non‑coding RNA HOTAIR promotes the progression of synovial sarcoma through microRNA‑126/stromal cell‑derived factor‑1 regulation

Qi Feng, Donglai Wang, Peng Guo, Zibo Zhang, Jiangang Feng

Article Number: 444 Published online on: 06 April 2021
Open Access

Elevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma

I-Neng Lee, Jen-Tsung Yang, Cheng Huang, Hsiu-Chen Huang, Yu-Ping Wu, Jui-Chieh Chen

Article Number: 443 Published online on: 06 April 2021
Open Access

LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β‑catenin signaling pathway and epithelial‑mesenchymal transition

Min Xu, Bangyi Lin, Danni Zheng, Jialiang Wen, Wenjing Hu, Chunxue Li, Xianwei Zhang, Xiaohua Zhang, Jinmiao Qu

Article Number: 442 Published online on: 02 April 2021
Open Access

Expression profiling of CPS1 in Correa's cascade and its association with gastric cancer prognosis

Xuqian Fang, Xiaoqiong Wu, Enfei Xiang, Fangxiu Luo, Qinqin Li, Qianchen Ma, Fei Yuan, Peizhan Chen

Article Number: 441 Published online on: 02 April 2021
Open Access

DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression

Mai-Qing Yang, Lin-Lin Bai, Zhao Wang, Lei Lei, Yi-Wen Zheng, Zhi-Han Li, Wen-Jing Huang, Chen-Chen Liu, Hong-Tao Xu

Article Number: 440 Published online on: 01 April 2021
Open Access

Potential role of mitochondria in gastric cancer detection: Fission and glycolysis (Review)

Hang Yang, Yan Li, Bing Hu

Article Number: 439 Published online on: 01 April 2021
Open Access

Recombinant protein TRAIL-Mu3 enhances the antitumor effects in pancreatic cancer cells by strengthening the apoptotic signaling pathway

Min Huang, Cheng Yi, Xian-Zhou Huang, Juan Yan, Li-Jia Wei, Wei-Ju Tang, Shou-Chun Chen, Ying Huang

Article Number: 438 Published online on: 01 April 2021
Open Access

Aquaporin 1 knockdown inhibits triple‑negative breast cancer cell proliferation and invasion in vitro and in vivo

Yinan Ji, Xiaoming Liao, Yi Jiang, Wei Wei, Huawei Yang

Article Number: 437 Published online on: 01 April 2021
Open Access

Ring finger 20/ring finger 40/WW domain‑containing adaptor with coiled‑coil complex interacts with p53 to regulate gene transcription in DNA damage response

Danni Meng, Kun Guo, Die Zhang, Cheng Zhao, Chuanwen Sun, Feng Zhang

Article Number: 436 Published online on: 01 April 2021
Open Access

β‑asarone suppresses HCT116 colon cancer cell proliferation and liver metastasis in part by activating the innate immune system

Min Chen, Yu-Wen Zhuang, Cun-En Wu, Hai-Yan Peng, Jun Qian, Jin-Yong Zhou

Article Number: 435 Published online on: 31 March 2021
Open Access

Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang

Article Number: 434 Published online on: 31 March 2021
Open Access

Lentivirus‑mediated silencing of CNTN1 enhances gefitinib sensitivity by reversing epithelial‑mesenchymal transition in lung adenocarcinoma A549 cells

Chun-Sheng Hu, Jiu-Hong Huang, Dong-Lin Yang, Chuan Xu, Zhi-Gang Xu, Hong-Bo Tan, Zhong-Zhu Chen

Article Number: 433 Published online on: 31 March 2021
Open Access

Activation of GPER by E2 promotes proliferation, invasion and migration of breast cancer cells by regulating the miR‑124/CD151 pathway

Huaicheng Yang, Congyu Wang, Heqiang Liao, Qi Wang

Article Number: 432 Published online on: 31 March 2021
Open Access

Siomycin A induces reactive oxygen species‑mediated cytotoxicity in ovarian cancer cells

Xiulan Shao, Fengying Zhang, Xiang Gao, Fengying Xu

Article Number: 431 Published online on: 31 March 2021
Open Access

Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity in tumor‑related genes in gastric cancer

Xueyun Huo, Xiaoqin Xiao, Shuangyue Zhang, Xiaoyan Du, Changlong Li, Zhigang Bai, Zhenwen Chen

Article Number: 430 Published online on: 30 March 2021
Open Access

lncRNA LINC00473 promotes proliferation, migration, invasion and inhibition of apoptosis of non‑small cell lung cancer cells by acting as a sponge of miR‑497‑5p

Shao-Hua Xu, Yu-Hong Bo, Han-Chen Ma, Hua-Nan Zhang, Ming-Ju Shao

Article Number: 429 Published online on: 30 March 2021
Open Access

Effects of a combined therapy of bortezomib and ionizing radiation on chondrosarcoma three-dimensional spheroid cultures

Birgit Lohberger, Dietmar Glaenzer, Nicole Eck, Bibiane Steinecker-Frohnwieser, Andreas Leithner, Beate Rinner, Sylvia Kerschbaum-Gruber, Dietmar Georg

Article Number: 428 Published online on: 30 March 2021
Journal Cover

June-2021
Volume 21 Issue 6

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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