Journal Articles

Open Access

IκB‑α: At the crossroad between oncogenic and tumor‑suppressive signals (Review)

Alessandro Morotti, Sabrina Crivellaro, Cristina Panuzzo, Giovanna Carrà, Angelo Guerrasio, Giuseppe Saglio

Pages: 531-534 Published online on: 06 December 2016

Familial risk for lung cancer (Review)

Madiha Kanwal, Xiao‑Ji Ding, Yi Cao

Pages: 535-542 Published online on: 20 December 2016
Open Access

From inflammation to gastric cancer: Role of Helicobacter pylori (Review)

Xiao-Ying Zhang, Pei-Ying Zhang, Mourad A.M. Aboul-Soud

Pages: 543-548 Published online on: 15 December 2016

A novel hysteroscopic approach for ovarian cancer screening/early diagnosis (Review)

Salvatore Gizzo, Marco Noventa, Michela Quaranta, Amerigo Vitagliano, Carlo Saccardi, Pietro Litta, Donato Antona

Pages: 549-553 Published online on: 14 December 2016
Open Access

Anti‑tumor effects of metformin on head and neck carcinoma cell lines: A systematic review

Daniela Fortunato Rêgo, Silvia Taveira Elias, Angélica Amorim Amato, Graziela De Luca Canto, Eliete Neves Silva Guerra

Pages: 554-566 Published online on: 20 December 2016
Open Access

Effect of targeted silencing of IL-8 on in vitro migration and invasion of SKOV3 ovarian cancer cells

Yanyu Li, Ling Liu, Zeyuan Yin, Hui Xu, Shuang Li, Wei Tao, Hui Cheng, Lei Du, Xueyuan Zhou, Bei Zhang

Pages: 567-572 Published online on: 16 December 2016
Open Access

MicroRNA‑320a downregulation mediates human liver cancer cell proliferation through the Wnt/β‑catenin signaling pathway

Caicheng Lu, Zengwei Liao, Minxian Cai, Guirong Zhang

Pages: 573-578 Published online on: 12 December 2016
Open Access

Human serum albumin-mediated apoptin delivery suppresses breast cancer cell growth in vitro and in vivo

Fang Wu, Yizhi Liu, Jian Li, Lei Hou, Fuxi Lei, Shangke Huang, Lu Feng, Xinhan Zhao

Pages: 579-586 Published online on: 07 December 2016
Open Access

DKK4 enhances resistance to chemotherapeutics 5‑Fu and YN968D1 in colorectal cancer cells

Shengli He, Jie Shen, Nanhua Hu, Xuanfu Xu, Jin Li

Pages: 587-592 Published online on: 06 December 2016
Open Access

A malignant inflammatory myofibroblastic tumor of the hypopharynx harboring the 3a/b variants of the EML4‑ALK fusion gene

Lucia Anna Muscarella, Giulio Rossi, Domenico Trombetta, Annamaria La Torre, Leonarda Di Candia, Maria Cecilia Mengoli, Angelo Sparaneo, Vito Michele Fazio, Paolo Graziano

Pages: 593-598 Published online on: 14 December 2016
Open Access

Melittin inhibits the invasion of MCF‑7 cells by downregulating CD147 and MMP‑9 expression

Jianjun Wang, Fengyu Li, Jiang Tan, Xuewei Peng, Lili Sun, Ping Wang, Shengnan Jia, Qingmiao Yu, Hongliang Huo, Hongyan Zhao

Pages: 599-604 Published online on: 20 December 2016
Open Access

Danshensu, a major water‑soluble component of Salvia miltiorrhiza, enhances the radioresponse for Lewis Lung Carcinoma xenografts in mice

Hong‑Ying Cao, Rui‑Lin Ding, Meng Li, Mao‑Nan Yang, Ling‑Lin Yang, Jing‑Bo Wu, Bo Yang, Jing Wang, Cui‑Lian Luo, Qing‑Lian Wen

Pages: 605-612 Published online on: 16 December 2016
Open Access

Resveratrol promotes regression of renal carcinoma cells via a renin‑angiotensin system suppression‑dependent mechanism

Jianchang Li, Mingning Qiu, Lieqian Chen, Lei Liu, Guobin Tan, Jianjun Liu

Pages: 613-620 Published online on: 20 December 2016
Open Access

Expression of Axl and its prognostic significance in human breast cancer

Gaoyuan Jin, Zhenzhen Wang, Jianguang Wang, Like Zhang, Yanbin Chen, Pengfei Yuan, Dechun Liu

Pages: 621-628 Published online on: 20 December 2016
Open Access

Identification of genes associated with tongue cancer in patients with a history of tobacco and/or alcohol use

Yin Zhao, Dongna Fu, Chengbi Xu, Jingpu Yang, Zonggui Wang

Pages: 629-638 Published online on: 14 December 2016
Open Access

Imbalanced adaptive responses associated with microsatellite instability in cholangiocarcinoma

Watcharin Loilome, Sasithorn Kadsanit, Kanha Muisook, Puangrat Yongvanit, Nisana Namwat, Anchalee Techasen, Anucha Puapairoj, Narong Khuntikeo, Pichai Phonjit

Pages: 639-646 Published online on: 08 December 2016
Open Access

Aspirin enhances the cytotoxic activity of bortezomib against myeloma cells via suppression of Bcl-2, survivin and phosphorylation of AKT

Jiang‑Hua Ding, Li‑Ya Yuan, Guo‑An Chen

Pages: 647-654 Published online on: 08 December 2016
Open Access

Anti-metastatic activity of fangchinoline in human gastric cancer AGS cells

Zhengrong Chen, Tengfei He, Kui Zhao, Chungen Xing

Pages: 655-660 Published online on: 02 December 2016
Open Access

LASS2 inhibits growth and invasion of bladder cancer by regulating ATPase activity

Haifeng Wang, Yigang Zuo, Mingxia Ding, Changxing Ke, Ruping Yan, Hui Zhan, Jingyu Liu, Wei Wang, Ning Li, Jiansong Wang

Pages: 661-668 Published online on: 20 December 2016
Open Access

Plasma miR‑145, miR‑20a, miR‑21 and miR‑223 as novel biomarkers for screening early‑stage non‑small cell lung cancer

Hui Zhang, Feng Mao, Tuyang Shen, Qingquan Luo, Zhengping Ding, Liqiang Qian, Jia Huang

Pages: 669-676 Published online on: 06 December 2016
Open Access

Evaluation of nano‑magnetic fluid on malignant glioma cells

Hongsheng Xu, Hailiang Zong, Chong Ma, Xing Ming, Ming Shang, Kai Li, Xiaoguang He, Lei Cao

Pages: 677-680 Published online on: 19 December 2016
Open Access

Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model

Meng Wang, Shi‑Ju Yan, Hong‑Tao Zhang, Nan Li, Tao Liu, Ying‑Long  Zhang, Xiao‑Xiang Li, Qiong Ma, Xiu‑Chun Qiu, Qing‑Yu Fan, Bao‑An Ma

Pages: 681-685 Published online on: 12 December 2016
Open Access

Downregulation of feline sarcoma-related protein inhibits cell migration, invasion and epithelial-mesenchymal transition via the ERK/AP-1 pathway in bladder urothelial cell carcinoma

Xudong Hu, Zhiqiang Zhang, Zhaofeng Liang, Dongdong Xie, Tao Zhang, Dexin Yu, Caiyun Zhong

Pages: 686-694 Published online on: 05 December 2016
Open Access

EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong‑Hui Li, Wen‑He Huang, Jun‑Dong Wu, Cai‑Wen Du, Guo‑Jun Zhang

Pages: 695-703 Published online on: 12 December 2016
Open Access

Association between XRCC1 and ERCC1 single‑nucleotide polymorphisms and the efficacy of concurrent radiochemotherapy in patients with esophageal squamous cell carcinoma

Xue Huang, Changmin Liu, Yayun Cui, Heping Zhang, Yongping Liu, Xifa Zhou, Judong Luo

Pages: 704-714 Published online on: 14 December 2016
Open Access

Expression of CHODL in hepatocellular carcinoma affects invasion and migration of liver cancer cells

Zejian Huang, Ning Zhang, Wenda Li, Jun Cao, Lei Zhang, Yajin Chen

Pages: 715-721 Published online on: 06 December 2016
Open Access

MicroRNA‑93‑5p increases multidrug resistance in human colorectal carcinoma cells by downregulating cyclin dependent kinase inhibitor 1A gene expression

Shi‑Jun Wang, Yun‑Fei Cao, Zu‑Qing Yang, Zhi‑Yuan Jiang, Bin Cai, Jiao Guo, Sen Zhang, Xiao‑Long Zhang, Feng Gao

Pages: 722-730 Published online on: 06 December 2016
Open Access

Forkhead transcription factor 1 inhibits endometrial cancer cell proliferation via sterol regulatory element‑binding protein 1

Yifang Zhang, Lili Zhang, Hengzi Sun, Qingtao Lv, Chunping Qiu, Xiaoxia Che, Zhiming Liu, Jie Jiang

Pages: 731-737 Published online on: 12 December 2016
Open Access

Alkaloids of fascaplysin are effective conventional chemotherapeutic drugs, inhibiting the proliferation of C6 glioma cells and causing their death in vitro

Igor Bryukhovetskiy, Irina Lyakhova, Polina Mischenko, Elena  Milkina, Sergei  Zaitsev, Yuri Khotimchenko, Andrey Bryukhovetskiy, Alexander  Polevshchikov, Igor Kudryavtsev, Maxim Khotimchenko, Maxim Zhidkov

Pages: 738-746 Published online on: 09 December 2016
Open Access

Multicenter phase II study of infusional 5‑fluorouracil (5‑FU), leucovorin, and oxaliplatin, plus biweekly cetuximab as first‑line treatment in patients with metastatic colorectal cancer (CELINE trial)

Masanori Kotake, Toru Aoyama, Yoshinori Munemoto, Kenji Doden, Masato Kataoka, Kenji Kobayashi, Genichi Nishimura, Hidehito Fujita, Keishi Nakamura, Akira Takehara, Chihiro Tanaka, Junichi Sakamoto, Naoki Nagata, Koji Oba, Ken Kondo

Pages: 747-753 Published online on: 14 December 2016
Open Access

Ursolic acid sensitizes radioresistant NSCLC cells expressing HIF‑1α through reducing endogenous GSH and inhibiting HIF‑1α

Bing Song, Qian Zhang, Maohu Yu, Xinrong Qi, Gang Wang, Linlin Xiao, Qiyi Yi, Wensen Jin

Pages: 754-762 Published online on: 07 December 2016
Open Access

P300 promotes migration, invasion and epithelial-mesenchymal transition in a nasopharyngeal carcinoma cell line

Zhi‑Wei Liao, Lei Zhao, Mu‑Yan Cai, Mian Xi, Li‑Ru He, Fang Yu, Tong‑Chong Zhou, Meng‑Zhong Liu

Pages: 763-769 Published online on: 13 December 2016

Autophagy impacts on oxaliplatin-induced hepatocarcinoma apoptosis via the IL-17/IL-17R-JAK2/STAT3 signaling pathway

Jinghua Wu, Jiapei Guo, Qing Cao, Yi Wang, Junmao Chen, Zhigang Wang, Zhiyong Yuan

Pages: 770-776 Published online on: 08 December 2016
Open Access

Bioinformatic identification of candidate genes induced by trichostatin A in BGC-823 gastric cancer cells

Yunlong Li, Lisha Zhang, Chunfa Yang, Riheng Li, Longbin Shang, Xiaoming Zou

Pages: 777-783 Published online on: 12 December 2016
Open Access

Effect of cancer/testis antigen NY‑SAR‑35 on the proliferation, migration and invasion of cancer cells

Myung‑Ha Song, Ye‑Rin Kim, Jae‑Ho Bae, Chang‑Hun Lee, Sang‑Yull Lee

Pages: 784-790 Published online on: 14 December 2016
Open Access

Induction of apoptosis by FFJ‑5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells

Xiaoli Wei, Ming Li, Mingming Ma, Huina Jia, Yu Zhang, Wenyi Kang, Tianxiao Wang, Xiaoyan Shi

Pages: 791-799 Published online on: 20 December 2016

2‑Deoxyglucose and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige

Pages: 800-804 Published online on: 16 December 2016

Comparative clinicopathological characteristics of colon and rectal T1 carcinoma

Katsuro Ichimasa, Shin‑Ei Kudo, Hideyuki Miyachi, Yuta Kouyama, Takemasa Hayashi, Kunihiko Wakamura, Tomokazu Hisayuki, Toyoki Kudo, Masashi Misawa, Yuichi Mori, Shingo Matsudaira, Eiji Hidaka, Shigeharu Hamatani, Fumio Ishida

Pages: 805-810 Published online on: 06 December 2016

Human antigen R as a predictive marker for response to gemcitabine‑based chemotherapy in advanced cisplatin‑resistant urothelial cancer

Yasuyoshi Miyata, Kensuke Mitsunari, Asai Akihiro, Shin‑Ichi Watanabe, Tomohiro Matsuo, Kojiro Ohba, Hideki Sakai

Pages: 811-818 Published online on: 12 December 2016

Prognostic significance of KLF4 expression in gastric cancer

Isaya Hashimoto, Takuya Nagata, Shinichi Sekine, Makoto Moriyama, Kazuto Shibuya, Shozo Hojo, Koshi Matsui, Isaku Yoshioka, Tomoyuki Okumura, Takashi Hori, Yutaka Shimada, Kazuhiro Tsukada

Pages: 819-826 Published online on: 14 December 2016

Overexpression of KAI1 inhibits retinoblastoma metastasis in vitro

Hui Yan, Xunda Ji, Jing Li, Lei Zhang, Peiquan Zhao

Pages: 827-833 Published online on: 16 December 2016

Stromal expression of Fer suppresses tumor progression in renal cell carcinoma and is a predictor of survival

Kensuke Mitsunari, Yasuyoshi Miyata, Shin‑Ichi Watanabe, Akihiro Asai, Takuji Yasuda, Shigeru Kanda, Hideki Sakai

Pages: 834-840 Published online on: 12 December 2016

Trametes robiniophila may induce apoptosis and inhibit MMPs expression in the human gastric carcinoma cell line MKN‑45

Xuening Ji, Chunxia Pan, Xiaowen Li, Yunbin Gao, Lu Xia, Xiulian Quan, Jinyan Lv, Ruoyu Wang

Pages: 841-846 Published online on: 20 December 2016

Bone metastasis from lung cancer identified by genetic profiling

Zhu‑Lin Liu, Chun Wang, Hui‑Jiao Chen, Xue Li, Li‑Jun Dai, Zhen‑Yu Ding

Pages: 847-850 Published online on: 02 December 2016

MicroRNA‑149 targets specificity protein 1 to suppress human tongue squamous cell carcinoma cell proliferation and motility

Jingxin Chen, Jimin Chen, Weizhong Li

Pages: 851-856 Published online on: 20 December 2016

Influence of gap junction intercellular communication composed of connexin 43 on the antineoplastic effect of adriamycin in breast cancer cells

Guojun Jiang, Shuying Dong, Meiling Yu, Xi Han, Chao Zheng, Xiaoguang Zhu, Xuhui Tong

Pages: 857-866 Published online on: 07 December 2016

Elevated microRNA-125b levels predict a worse prognosis in HER2-positive breast cancer patients

Yanwei Luo, Xinye Wang, Weihong Niu, Heran Wang, Qiuyuan Wen, Songqing Fan, Ran Zhao, Zheng Li, Wei Xiong, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Guiyuan Li, Ming Tan, Ming Zhou

Pages: 867-874 Published online on: 12 December 2016

Wild-type p53-induced phosphatase 1 is a prognostic marker and therapeutic target in bladder transitional cell carcinoma

Zhi‑Peng Wang, Shu‑Yuan Chen, Ye Tian

Pages: 875-880 Published online on: 08 December 2016

Patients with normal‑range CA19‑9 levels represent a distinct subgroup of pancreatic cancer patients

Guopei Luo, Kaizhou Jin, Meng Guo, He Cheng, Zuqiang Liu, Zhiwen Xiao, Yu Lu, Jiang Long, Liang Liu, Jin Xu, Chen Liu, Yutang Gao, Quanxing Ni, Xianjun Yu

Pages: 881-886 Published online on: 14 December 2016
Open Access

Gastrointestinal stromal tumor with a PDGFRA mutation masquerading as gastric plexiform fibromyxoma: A comparative clinicopathological study of two cases

Jun Zhou, Jingjing Xu, Guozhong Jiang, Yihui Ma, Jingwen Qi, Wencai Li, Dandan Zhang

Pages: 887-892 Published online on: 12 December 2016

Potential regulation of glioma through the induction of apoptosis signaling via Egl‑9 family hypoxia‑inducible factor 3

Ke Mao, Chao You, Ding Lei, Heng Zhang

Pages: 893-897 Published online on: 14 December 2016

CD147 promotes the proliferation, invasiveness, migration and angiogenesis of human lung carcinoma cells

Shaoxing Yang, Fei Qi, Chuanhao Tang, Hong Wang, Haifeng Qin, Xiaoyan Li, Jianjie Li, Weixia Wang, Changyun Zhao, Hongjun Gao

Pages: 898-904 Published online on: 14 December 2016

Clinical significance of platelet‑derived growth factor receptor‑β gene expression in stage II/III gastric cancer with S‑1 adjuvant chemotherapy

Akio Higuchi, Takashi Oshima, Kazue Yoshihara, Kentaro Sakamaki, Toru Aoyama, Nobuyasu Suganuma, Naoto Yamamoto, Tsutomu Sato, Haruhiko Cho, Manabu Shiozawa, Takaki Yoshikawa, Yasushi Rino, Chikara Kunisaki, Toshio Imada, Munetaka Masuda

Pages: 905-911 Published online on: 14 December 2016

Reproducibility of the EGFR immunohistochemistry scores for tumor samples from patients with advanced non-small cell lung cancer

Alejandro Avilés‑Salas, Saé Muñiz‑Hernández, Héctor Aquiles Maldonado‑Martínez, José G. Chanona‑Vilchis, Laura‑Alejandra Ramírez‑Tirado, Norma Hernández‑Pedro, Rita Dorantes‑Heredia, José Manuel Ruíz‑Morales, Daniel Motola‑Kuba, Oscar Arrieta

Pages: 912-920 Published online on: 16 December 2016

Inhibition of store‑operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate

Wei Huang, Caiping Ren, Guoling Huang, Jie Liu, Weidong Liu, Lei Wang, Bin Zhu, Xiangling Feng, Jia Shi, Jinlong Li, Xiaomeng Xia, Wei Jia, Jiawen Chen, Yuxiang Chen, Xingjun Jiang

Pages: 921-929 Published online on: 07 December 2016

Regulation of cell migration via the EGFR signaling pathway in oral squamous cell carcinoma cells

Yuichi Ohnishi, Hiroki Yasui, Kenji Kakudo, Masami Nozaki

Pages: 930-936 Published online on: 14 December 2016

Characteristic expression of fukutin in gastric cancer among atomic bomb survivors

Trang T.B. Pham, Naohide Oue, Manabu Yamamoto, Megumu Fujihara, Teruyoshi Ishida, Shoichiro Mukai, Naoya Sakamoto, Kazuhiro Sentani, Wataru Yasui

Pages: 937-941 Published online on: 20 December 2016

DHX32 expression is an indicator of poor breast cancer prognosis

Meng Wang, Guojun Zhang, Yajie Wang, Ruimin Ma, Limin Zhang, Hong Lv, Fang Fang, Xixiong Kang

Pages: 942-948 Published online on: 14 December 2016

TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo

Qing Guo, Jia He, Feng Shen, Wei Zhang, Xi Yang, Chi Zhang, Qu Zhang, Jun‑Xing Huang, Zheng‑Dong Wu, Xin‑Chen Sun, Sheng‑Bin Dai

Pages: 949-954 Published online on: 20 December 2016

Molecular mechanisms of cholangiocarcinoma cell inhibition by medicinal plants

Surang Leelawat, Kawin Leelawat

Pages: 961-966 Published online on: 12 December 2016

Hypoxia regulates CD44 expression via hypoxia-inducible factor-1α in human gastric cancer cells

Gai Liang, Shuang Li, Wei Du, Qinghua Ke, Jun Cai, Jiyuan Yang

Pages: 967-972 Published online on: 08 December 2016

Pro-apoptotic and anti-proliferative effects of corn silk extract on human colon cancer cell lines

Hao Guo, Hong Guan, Wenqin Yang, Han Liu, Huiling Hou, Xue Chen, Zhenyan Liu, Chuangang Zang, Yuchao Liu, Jicheng Liu

Pages: 973-978 Published online on: 05 December 2016

Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report

Morena Fasano, Alessio Fabozzi, Guido Giordano, Filippo Venturini, Gaetano Aurilio, Flavia Cantile, Teresa Fabozzi, Vincenzo Ricci, Giuseppe Santabarbara, Floriana Morgillo, Fortunato Ciardiello, Ferdinando De Vita

Pages: 979-983 Published online on: 20 December 2016

Sorafenib therapy following resection prolongs disease‑free survival in patients with advanced hepatocellular carcinoma at a high risk of recurrence

Yadi Liao, Yun Zheng, Wei He, Qijiong Li, Jingxian Shen, Jian Hong, Ruhai Zou, Jiliang Qiu, Binkui Li, Yunfei Yuan

Pages: 984-992 Published online on: 20 December 2016

Single nucleotide polymorphisms of the haptoglobin gene in non-small cell lung cancer treated with personalized peptide vaccination

Kayoko Waki, Teppei Yamada, Koichi Yoshiyama, Yasuhiro Terazaki, Shinjiro Sakamoto, Shunichi Sugawara, Shinzo Takamori, Kyogo Itoh, Akira Yamada

Pages: 993-999 Published online on: 07 December 2016

Prognostic significance of the preoperative lymphocyte‑to‑monocyte ratio in patients with colorectal cancer

Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Yasuhito Iseki, Tetsuro Ikeya, Kosei Hirakawa

Pages: 1000-1006 Published online on: 12 December 2016

Arctigenin, a natural lignan compound, induces G0/G1 cell cycle arrest and apoptosis in human glioma cells

Aisha Maimaitili, Zunhua Shu, Xiaojiang Cheng, Kadeer Kaheerman, Alifu Sikandeer, Weimin Li

Pages: 1007-1013 Published online on: 08 December 2016

Primary breast lymphoma: A single center study

Na Zhang, Caineng Cao, Yuan Zhu, Peng Liu, Luying Liu, Ke Lu, Jialin Luo, Ning Zhou

Pages: 1014-1018 Published online on: 12 December 2016

Pinus massoniana bark extract inhibits migration of the lung cancer A549 cell line

Ping Mao, Ershao Zhang, Yang Chen, Likun Liu, Daqing Rong, Qingfeng Liu, Weiling Li

Pages: 1019-1023 Published online on: 16 December 2016

Apigenin enhances the cisplatin cytotoxic effect through p53‑modulated apoptosis

Rui Liu, Ping Ji, Bin Liu, Haishi Qiao, Xia Wang, Likun Zhou, Ting Deng, Yi Ba

Pages: 1024-1030 Published online on: 14 December 2016
Journal Cover

February 2017
Volume 13 Issue 2

Print ISSN: 1792-1074
Online ISSN: 1792-1082

2015 Impact Factor: 1.482
Ranked #97/211 Oncology
(total number of cites)

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