Journal Articles

Article Open Access

CTBP1 strengthens the cisplatin resistance of gastric cancer cells by upregulating RAD51 expression

Yuluo Wu, Haiyang Zhao

Article Number: 810 Published online on: 27 September 2021
Review Open Access

Towards an updated view on the clinical management of pancreatic adenocarcinoma: Current and future perspectives (Review)

Leonel Pekarek, Oscar Fraile‑Μartinez, Cielo Garcia‑Montero, Miguel A. Alvarez‑Mon, Julio Acero, Lidia Ruiz‑Llorente, Natalio García‑Honduvilla, Agustin Albillos, Julia Buján, Melchor Alvarez‑Mon, Luis G. Guijarro, Miguel A. Ortega

Article Number: 809 Published online on: 27 September 2021
Article Open Access

MicroRNA‑135a expression is upregulated in hepatocellular carcinoma and targets long non‑coding RNA TONSL‑AS1 to suppress cell proliferation

Xuesong Deng, Jun Cheng, Naiyang Zhan, Jianwei Chen, Yongqiang Zhan, Yong Ni, Caixian Liao

Article Number: 808 Published online on: 24 September 2021
Article Open Access

Response of human cancer cells to simultaneous treatment with sorafenib and radiofrequency current

María Luisa Hernández‑Bule, María Antonia Martínez, María Ángeles Trillo, Lidia Martínez, Elena Toledano‑Macías, Alejandro Úbeda

Article Number: 807 Published online on: 23 September 2021
Review Open Access

Influence of cultural practices on breast cancer risks, stage at presentation and outcome in a multi‑ethnic developing country (Review)

Norlia Abdullah, Norazlina Mohamed

Article Number: 806 Published online on: 23 September 2021
Article Open Access

miR‑148a, miR‑152 and miR‑200b promote prostate cancer metastasis by targeting DNMT1 and PTEN expression

Venhar Gurbuz, Sinan Sozen, Cenk Y. Bilen, Ece Konac

Article Number: 805 Published online on: 23 September 2021
Article Open Access

β2‑adrenergic receptor expression and the effects of norepinephrine and propranolol on various head and neck cancer subtypes

Soon Young Kwon, Kyung Ju Chun, Hong Kwon Kil, Narae Jung, Hyun-Ah Shin, Jeon Yeob Jang, Hyo Geun Choi, Kyoung-Ho Oh, Min-Su Kim

Article Number: 804 Published online on: 23 September 2021
Article Open Access

Analysis of expression profiles and prognostic value of COP9 signalosome subunits for patients with head and neck squamous cell carcinoma

Hao Zhou, Wei Sun, Jiaruan Zou

Article Number: 803 Published online on: 23 September 2021
Article Open Access

Long non‑coding RNA NEAT1 promotes the malignancy of laryngeal squamous cell carcinoma by regulating the microRNA‑204‑5p/SEMA4B axis

Ling Han, Chaopan Zheng, Shihai Wu

Article Number: 802 Published online on: 23 September 2021
Article Open Access

Long non‑coding RNA XIST accelerates hepatic carcinoma progression by targeting the microRNA‑320a/PIK3CA axis

Lina Yang, Fangliang Xie, Weidong Xu, Tonglei Xu, Yuan Ni, Xiao Tao, Yu Zang, Juan Jin

Article Number: 801 Published online on: 23 September 2021
Retraction Open Access

[Retracted] Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer

Tomoya Kato, Mikihito Nakamori, Shuichi Matsumura, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue

Article Number: 800 Published online on: 22 September 2021
Article Open Access

Circular RNA ATAD1 is upregulated in acute myeloid leukemia and promotes cancer cell proliferation by downregulating miR‑34b via promoter methylation

Yarong Wu, Bingjun Gao, Xiaolei Qi, Liyun Bai, Bixin Li, Hongjing Bao, Xi Wu, Xiaoyun Wu, Yuxia Zhao

Article Number: 799 Published online on: 20 September 2021
Article Open Access

Knockdown of lncRNA NUTM2A‑AS1 inhibits lung adenocarcinoma cell viability by regulating the miR‑590‑5p/METTL3 axis

Jie Wang, Jingyun Zha, Xiaolin Wang

Article Number: 798 Published online on: 20 September 2021
Article Open Access

Targeting Mps1 in combination with paclitaxel inhibits osteosarcoma progression by modulating spindle assembly checkpoint and Akt/mTOR signaling

Lu Lu, Yuhai Wang, Jian Chen, Ye Li, Qingyang Liang, Feng Li, Chuanchuan Zhen, Kegong Xie

Article Number: 797 Published online on: 17 September 2021
Article

lncRNA CYTOR promotes cell proliferation and tumor growth via miR‑125b/SEMA4C axis in hepatocellular carcinoma

Qing Tian, Xiaodong Yan, Long Yang, Zirong Liu, Zheyue Yuan, Yamin Zhang

Article Number: 796 Published online on: 17 September 2021
Article Open Access

GHSR methylation‑dependent expression of a variant ligand and receptor of the ghrelin system induces thymoma tumorigenesis

Bilguun Tegshee, Kazuya Kondo, Shiho Soejima, Kyoka Muguruma, Mitsuhiro Tsuboi, Koichiro Kajiura, Yukikiyo Kawakami, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku

Article Number: 793 Published online on: 17 September 2021
Article

Four plasma miRNAs act as biomarkers for diagnosis and prognosis of non‑small cell lung cancer

He-Guo Jiang, Chun-Hua Dai, Ya-Ping Xu, Qian Jiang, Xian-Bin Xia, Yang Shu, Jian Li

Article Number: 792 Published online on: 17 September 2021
Article Open Access

HMBS is the most suitable reference gene for RT‑qPCR in human HCC tissues and blood samples

Hye Ri Ahn, Geum Ok Baek, Moon Gyeong Yoon, Juan A Son, Donglim You, Jung Hwan Yoon, Hyoung Jung Cho, Soon Sun Kim, Jae Yeon Cheong, Jung Woo Eun

Article Number: 791 Published online on: 17 September 2021
Article Open Access

Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity

Nanaka Morita, Masato Hoshi, Takeshi Hara, Soranobu Ninomiya, Taisuke Enoki, Misao Yoneda, Hisashi Tsurumi, Kuniaki Saito

Article Number: 790 Published online on: 17 September 2021
Article Open Access

Microarray analysis of differentially expressed long non‑coding RNAs in daidzein‑treated lung cancer cells

Laifang Li, Jun Liu, Xiaobo Wang, Xiaowei Xiong, Shaoxin Huang, Xin Wang

Article Number: 789 Published online on: 17 September 2021
Article Open Access

Efficacy and safety of humanized CD19 CAR‑T as a salvage therapy for recurrent CNSL of B‑ALL following murine CD19 CAR‑T cell therapy

Xin Li, Mei-Jing Liu, Nan Mou, Zhen-Xing Yang, Jia  Wang, Juan Mu, Hai-Bo Zhu, Qi Deng

Article Number: 788 Published online on: 16 September 2021
Review Open Access

Immune checkpoints and immunotherapy in non‑small cell lung cancer: Novel study progression, challenges and solutions (Review)

Lin-Rui Ma, Jia-Xin Li, Ling Tang, Run-Ze Li, Jia-Shun Yang, Ao Sun, Elaine Lai‑Han Leung, Pei-Yu Yan

Article Number: 787 Published online on: 14 September 2021
Article Open Access

Protein overexpression of toll‑like receptor 4 and myeloid differentiation factor 88 in oral squamous cell carcinoma and clinical significance

Lili Li, Zhuoqian Zhou, Khangvu Mai, Ping Li, Zongqi Wang, Yaxi Wang, Yang Cao, Xuemeng Ma, Tingting Zhang, Daiyou Wang

Article Number: 786 Published online on: 14 September 2021
Review Open Access

An overview of mesenchymal stem cells and their potential therapeutic benefits in cancer therapy (Review)

Shern Kwok Lim, Boon Yin Khoo

Article Number: 785 Published online on: 14 September 2021
Article Open Access

Maternally expressed 3 inhibits the biological activity of oral squamous cell carcinoma SCC25 and CAL27 cell lines

Wenjing Wang, Huanju Li, Yongle Qiu, Kunshan Li, Yueting Lu, Qianlan Deng, Tiejun Liu

Article Number: 784 Published online on: 13 September 2021
Article Open Access

Effect of neutropenia on survival outcomes of patients with metastatic colorectal cancer receiving trifluridine/tipiracil plus bevacizumab

Daisaku Kamiimabeppu, Hiroki Osumi, Eiji Shinozaki, Akira Ooki, Takeru Wakatsuki, Koichiro Yoshino, Taro Sato, Izuma Nakayama, Mariko Ogura, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi

Article Number: 783 Published online on: 13 September 2021
Article Open Access

NDRG4 sensitizes CRC cells to 5‑FU by upregulating DDIT3 expression

Ruikai Li, Chenxiang He, Liangliang Shen, Shuai Wang, Yao Shen, Fan Feng, Jian Zhang, Jianyong Zheng

Article Number: 782 Published online on: 13 September 2021
Article Open Access

Ferroptosis is involved in the anti‑tumor effect of lycorine in renal cell carcinoma cells

Yang Du, Hong-Chao Zhao, Heng-Cheng Zhu, Yao Jin, Lei Wang

Article Number: 781 Published online on: 13 September 2021
Article

Identification of soluble tissue‑derived biomarkers from human thyroid tissue explants maintained on a microfluidic device

Andrew Riley, Heidi Jones, James England, Dmitriy Kuvshinov, Victoria Green, John Greenman

Article Number: 780 Published online on: 13 September 2021
Article Open Access

Repurposing non‑invasive prenatal testing data: Population study of single nucleotide variants associated with colorectal cancer and Lynch syndrome

Natalia Forgacova, Juraj Gazdarica, Jaroslav Budis, Jan Radvanszky, Tomas Szemes

Article Number: 779 Published online on: 13 September 2021
Article Open Access

Dynamic contrast‑enhanced MRI as a predictor of programmed death ligand‑1 expression in patients with oral squamous cell carcinoma

Nouha Tekiki, Mariko Fujita, Tatsuo Okui, Hotaka Kawai, May Wathone Oo, Toshiyuki Kawazu, Miki Hisatomi, Shunsuke Okada, Yohei Takeshita, Majd Barham, Hitoshi Nagatsuka, Yoshinobu Yanagi, Jun-Ichi Asaumi

Article Number: 778 Published online on: 13 September 2021
Article Open Access

Construction and validation of nomograms for non‑metastatic Ewing sarcoma: A prognostic factor analysis based on the SEER database

Runzhi Huang, Dong Han, Chengcheng Shi, Penghui Yan, Peng Hu, Xiaolong Zhu, Huabin Yin, Tong Meng, Zongqiang Huang

Article Number: 777 Published online on: 13 September 2021
Article Open Access

PET/MRI is useful for early detection of pelvic insufficiency fractures after radiotherapy for cervical cancer

Maho Azumi, Masuyo Matsumoto, Kaho Suzuki, Ryohei Sasaki, Yoshiko Ueno, Munenobu Nogami, Yoshito Terai

Article Number: 776 Published online on: 10 September 2021
Review Open Access

Research progress concerning m6A methylation and cancer (Review)

Yang Zhou, Jie Yang, Zheng Tian, Jing Zeng, Weigan Shen

Article Number: 775 Published online on: 10 September 2021
Article Open Access

Reduced tissue and serum resistin expression as a clinical marker for esophageal squamous cell carcinoma

Amos C. Hung, Yen-Yun Wang, Kun-Tsung Lee, Hung-Hsing Chiang, Yuk-Kwan Chen, Je-Kang Du, Chun-Ming Chen, Michael Yuanchien Chen, Kwei-Jing Chen, Stephen Chu-Sung Hu, Shyng-Shiou F. Yuan

Article Number: 774 Published online on: 10 September 2021
Article Open Access

Long non‑coding RNA TMCC1‑AS1 predicts poor prognosis and accelerates epithelial‑mesenchymal transition in liver cancer

Cheng Chen, Na Su, Guiying Li, Yanfeng Shen, Xiaoting Duan

Article Number: 773 Published online on: 09 September 2021
Article Open Access

Long non‑coding RNA UCA1 enhances cervical cancer cell proliferation and invasion by regulating microRNA‑299‑3p expression

Ming An, Xuefeng Xing, Tonghua Chen

Article Number: 772 Published online on: 09 September 2021
Article Open Access

Oncotype DX 21‑gene test has a low recurrence score in both pure and mixed mucinous breast carcinoma

Rui Chen, Yun Wang, Taolang Li, Junyuan Lv, Guoli Feng, Na Tan, Jinjing Wang, Xiaoming Cheng

Article Number: 771 Published online on: 09 September 2021
Review Open Access

Cross‑link between ferroptosis and nasopharyngeal carcinoma: New approach to radiotherapy sensitization (Review)

Hai-Long Li, Nian-Hua Deng, Jia-Xin Xiao, Xiu-Sheng He

Article Number: 770 Published online on: 09 September 2021
Article Open Access

Inhibition of Dishevelled‑2 suppresses the biological behavior of pancreatic cancer by downregulating Wnt/β‑catenin signaling

Wei Hu, Mingxu Li, Junyi Wu, Hong Chen, Ting  Zhao, Chunjie Zhang, Zhong Wang

Article Number: 769 Published online on: 08 September 2021
Article Open Access

Itraconazole improves survival outcomes in patients with colon cancer by inducing autophagic cell death and inhibiting transketolase expression

Pei-Wen Shen, Yu-Mei Chou, Chia-Ling Li, En-Chih Liao, Hung-Sen Huang, Chun-Hao Yin, Chien-Liang Chen, Sheng-Jie Yu

Article Number: 768 Published online on: 08 September 2021
Article Open Access

Propofol induces the ferroptosis of colorectal cancer cells by downregulating STAT3 expression

Xining Zhao, Fei Chen

Article Number: 767 Published online on: 08 September 2021
Article Open Access

Nanoscale Au@SiO2‑drug/VEGF as an in vivo probe for osteosarcoma diagnosis and therapy

Tiangui Chen, Tianbo Li, Jiangning Wang

Article Number: 766 Published online on: 08 September 2021
Article Open Access

LAPTM4B promotes the progression of bladder cancer by stimulating cell proliferation and invasion

Yanhua Yin, Yanyan Fan, Gang Yu, Ying Du

Article Number: 765 Published online on: 08 September 2021
Article Open Access

Double‑stranded RNA‑specific adenosine deaminase‑knockdown inhibits the proliferation and induces apoptosis of DU145 and PC3 cells by promoting the phosphorylation of H2A.X variant histone

Xiezhao Li, Rui Zhu, Yaoji Yuan, Zhiduan Cai, Siyang Liang, Jun Bian, Guibin Xu

Article Number: 764 Published online on: 08 September 2021
Article Open Access

MicroRNA‑545‑5p regulates apoptosis, migration and invasion of osteosarcoma by targeting dimethyladenosine transferase 1

Hai-Zhen Zhou, Bo Chen, Xiao-Ju Li, Juan-Juan Du, Nan Zhang, Yu-Xiong Shao, Kun Zhang, Zhi-Chao Tong

Article Number: 763 Published online on: 06 September 2021
Article Open Access

circRNA circ_POLA2 increases microRNA‑31 methylation to promote endometrial cancer cell proliferation

Xia Fang, Jinhua Wang, Lingying Chen, Xiaochun Zhang

Article Number: 762 Published online on: 06 September 2021
Article Open Access

Role of NELF‑B in supporting epithelial‑mesenchymal transition and cell proliferation during hepatocellular carcinoma progression

Mennatallah Hani Ghouraba, Razan Jamil Masad, Eric Zadok Mpingirika, Omnia Mahmoud Abdelraheem, Rached Zeghlache, Aya M Alserw, Asma Amleh

Article Number: 761 Published online on: 06 September 2021
Article Open Access

Association between the expression of core 3 synthase and survival outcomes of patients with cholangiocarcinoma

Patcharaporn Boottanun, Yoshinori Ino, Kazuaki Shimada, Nobuyoshi Hiraoka, Kiyohiko Angata, Hisashi Narimatsu

Article Number: 760 Published online on: 03 September 2021
Article

Antiproliferative effect of GTS‑21 in glioblastoma cells

Malgorzata A. Kolodziej, Hanna Gött, Benjamin Kopischke, Michael K.F. Bender, Markus A. Weigand, Pietro Di Fazio, Frank P. Schwarm, Florian Uhle

Article Number: 759 Published online on: 02 September 2021
Review Open Access

The mechanism of non‑coding RNAs in medulloblastoma (Review)

Ying-Nan Zhao, Kun Li, Xing-Sheng Han, Ya-Wen Pan

Article Number: 758 Published online on: 02 September 2021
Article Open Access

Knockdown of lncRNA C5orf66‑AS1 inhibits osteosarcoma cell proliferation and invasion via miR‑149‑5p upregulation

Hui Zhang, Jie Song

Article Number: 757 Published online on: 02 September 2021
Article Open Access

UCHL3 plays an important role in the occurrence and development of melanoma

Runzhi He, Yajing Zhou, Jianmin Liu, Xiaochong Zhang, Xiaoling Zhao, Lihui An, Zihan Li, Fang Cheng

Article Number: 756 Published online on: 01 September 2021
Article Open Access

T‑box 2 expression is a useful indicator of the response to neoadjuvant chemotherapy for patients with locally advanced uterine cervical squamous cell carcinoma

Yuta Inoue, Takeshi Fukuda, Shigenori Nanno, Yuichiro Awazu, Masahiro Shimomura, Hiroaki Matsubara, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi

Article Number: 755 Published online on: 31 August 2021
Article Open Access

EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun

Article Number: 754 Published online on: 31 August 2021
Article Open Access

Screening and identification of differentially expressed microRNAs in diffuse large B‑cell lymphoma based on microRNA microarray

Hai-Xia Gao, Si-Jing Li, Meng-Bo Wang, Shu-Fang Yan, Wen-Li Cui, Zhi-Ping Ma, Jing Xue, Wei Sang, Wei Zhang, Xin-Xia Li

Article Number: 753 Published online on: 27 August 2021
Article Open Access

MicroRNA‑382‑5p inhibits osteosarcoma development and progression by negatively regulating VEZF1 expression

Hui Wu, Yu-Xi Luo, Wen Hu, Mao-Lin Zhao, Jun Bie, Mi Yang, Rongqiang Pan, Nan-Xiang Huang, Gang Feng, Kang Liu, Guiqin Song

Article Number: 752 Published online on: 27 August 2021
Article

Expression of oncogenic long noncoding RNA PSMG3‑antisense 1 in lung squamous cell carcinoma

E Jin, Chao Huang, Lei Zhang, Shiyi Chen, Xiaochen Zhao, Zheng Ren, Hong Fu

Article Number: 751 Published online on: 27 August 2021
Review Open Access

Progress on the study of the anticancer effects of artesunate (Review)

Xiulan Yang, Yudong Zheng, Lian Liu, Jiangrong Huang, Fei Wang, Jie Zhang

Article Number: 750 Published online on: 27 August 2021
Article Open Access

Anti‑Axl monoclonal antibodies attenuate the migration of MDA‑MB‑231 breast cancer cells

Hong Chang, Ran An, Xinying Li, Xiaoling Lang, Jiannan Feng, Ming Lv

Article Number: 749 Published online on: 27 August 2021
Review Open Access

Role of Toll‑like receptors in natural killer cell function in acute lymphoblastic leukemia (Review)

Janet Gallardo‑Zapata, Carmen Maldonado‑Bernal

Article Number: 748 Published online on: 24 August 2021
Article Open Access

CRMP5 regulates cell proliferation and development of colorectal cancer via MAPK‑dependent signaling

Fanghua Qiu, Lin Yu, Daoli Liu, Yujin Wu, Feng Qiu

Article Number: 747 Published online on: 24 August 2021
Article

Pan‑RAF inhibitor LY3009120 is highly synergistic with low‑dose cytarabine, but not azacitidine, in acute myeloid leukemia with RAS mutations

Jihyun Park, Hyejoo Park, Ja Min Byun, Junshik Hong, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon

Article Number: 745 Published online on: 20 August 2021
Journal Cover

November-2021
Volume 22 Issue 5

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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