Journal Articles

Open Access

Human papilloma virus: Apprehending the link with carcinogenesis and unveiling new research avenues (Review)

Daniel Boda, Anca Oana Docea, Daniela Calina, Mihaela Adriana Ilie, Constantin Caruntu, Sabina Zurac, Monica Neagu, Carolina Constantin, Daciana Elena Branisteanu, Vlad Voiculescu, Charalampos Mamoulakis, George Tzanakakis, Demetrios A. Spandidos, Nikolaos Drakoulis, Aristides M. Tsatsakis

Pages: 637-655 Published online on: 29 January 2018
Open Access

Gene expression profiling of acute myeloid leukemia samples from adult patients with AML-M1 and -M2 through boutique microarrays, real-time PCR and droplet digital PCR

Luiza Handschuh, Maciej Kaźmierczak, Marek C. Milewski, Michał Góralski, Magdalena Łuczak, Marzena Wojtaszewska, Barbara Uszczyńska-Ratajczak, Krzysztof Lewandowski, Mieczysław Komarnicki, Marek Figlerowicz

Pages: 656-678 Published online on: 28 December 2017
Open Access

Development of single nanometer-sized ultrafine oxygen bubbles to overcome the hypoxia-induced resistance to radiation therapy via the suppression of hypoxia-inducible factor‑1α

Misaki Iijima, Navchaa Gombodorj, Yoshiaki Tachibana, Kohsuke Tachibana, Takehiko Yokobori, Kyoko Honma, Takashi Nakano, Takayuki Asao, Ryusuke Kuwahara, Kazuhiro Aoyama, Hidehiro Yasuda, Matthew Kelly, Hiroyuki Kuwano, Dai Yamanouchi

Pages: 679-686 Published online on: 18 January 2018
Open Access

Eradication of cervical cancer in vivo by an AAV vector that encodes shRNA targeting human papillomavirus type 16 E6/E7

Naoto Sato, Yasushi Saga, Ryosuke Uchibori, Tomonori Tsukahara, Masashi Urabe, Akihiro Kume, Hiroyuki Fujiwara, Mitsuaki Suzuki, Keiya Ozawa, Hiroaki Mizukami

Pages: 687-696 Published online on: 15 January 2018
Open Access

Plasma-stimulated medium kills TRAIL-resistant human malignant cells by promoting caspase-independent cell death via membrane potential and calcium dynamics modulation

Tomohiko Tokunaga, Takashi Ando, Miki Suzuki-Karasaki, Tomohisa Ito, Asuka Onoe-Takahashi, Toyoko Ochiai, Masayoshi Soma, Yoshihiro Suzuki-Karasaki

Pages: 697-708 Published online on: 23 January 2018
Open Access

Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma

Yong Yang, Tiantian Lei, Suya Du, Rongsheng Tong, Hailian Wang, Jiao Yang, Juan Huang, Minghan Sun, Yi Wang, Zhi Dong

Pages: 709-720 Published online on: 04 January 2018
Open Access

CD133 expression predicts post-operative recurrence in patients with colon cancer with peritoneal metastasis

Hiroshi Nagata, Soichiro Ishihara, Junko Kishikawa, Hirofumi Sonoda, Koji Murono, Shigenobu Emoto, Manabu Kaneko, Kazuhito Sasaki, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Keisuke Hata, Kazushige Kawai, Hiroaki Nozawa

Pages: 721-732 Published online on: 08 January 2018
Open Access

Proteomics-based investigation of multiple stages of OSCC development indicates that the inhibition of Trx-1 delays oral malignant transformation

Xijuan Chen, Qinchao Hu, Tong Wu, Chunyang Wang, Juan Xia, Linglan Yang, Bin Cheng, Xiaobing Chen

Pages: 733-742 Published online on: 03 January 2018
Open Access

Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-000911/miR-449a pathway in breast carcinogenesis

Honglei Wang, Yi Xiao, Li Wu, Dachang Ma

Pages: 743-754 Published online on: 05 February 2018
Open Access

PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients

Magdalena Absmaier, Rudolf Napieralski, Tibor Schuster, Michaela Aubele, Axel Walch, Viktor Magdolen, Julia Dorn, Eva Gross, Nadia Harbeck, Aurelia Noske, Marion Kiechle, Manfred Schmitt

Pages: 755-767 Published online on: 08 January 2018
Open Access

Effects of cell-cell crosstalk on gene expression patterns in a cell model of renal cell carcinoma lung metastasis

Katarzyna Kaminska, Anna M. Czarnecka, Mohammed Imran Khan, Wojciech Fendler, Aleksandra Klemba, Pawel Krasowski, Ewa Bartnik, Cezary Szczylik

Pages: 768-786 Published online on: 29 December 2017
Open Access

Tumorigenic proteins upregulated in the MYCN-amplified IMR-32 human neuroblastoma cells promote proliferation and migration

Hayat Zaatiti, Jad Abdallah, Zeina Nasr, George Khazen, Anthony Sandler, Tamara J. Abou-Antoun

Pages: 787-803 Published online on: 04 January 2018
Open Access

BI2536, a potent and selective inhibitor of polo-like kinase 1, in combination with cisplatin exerts synergistic effects on gastric cancer cells

Guodong Lian, Leping Li, Yulong Shi, Changqing Jing, Jinglei Liu, Xiaobo Guo, Qingqing Zhang, Tianyu Dai, Fei Ye, Yanyan Wang, Man Chen

Pages: 804-814 Published online on: 25 January 2018
Open Access

miR‑149‑5p promotes chemotherapeutic resistance in ovarian cancer via the inactivation of the Hippo signaling pathway

Manman Xu, Juan Xiao, Ming Chen, Linjing Yuan, Jundong Li, Hongwei Shen, Shuzhong Yao

Pages: 815-827 Published online on: 24 January 2018

Inhibition of RPTOR overcomes resistance to EGFR inhibition in triple-negative breast cancer cells

Kyu Sic You, Yong Weon Yi, Sahng-June Kwak, Yeon-Sun Seong

Pages: 828-840 Published online on: 15 January 2018

MicroRNA-205-5p suppresses the invasiveness of oral squamous cell carcinoma by inhibiting TIMP‑2 expression

Hiroki Nagai, Shogo Hasegawa, Fumihiko Uchida, Takehito Terabe, Naomi Ishibashi Kanno, Koroku Kato, Kenji Yamagata, Satoshi Sakai, Shuichi Kawashiri, Hiroshi Sato, Toru Yanagawa, Hiroki Bukawa

Pages: 841-850 Published online on: 31 January 2018

Analysis of the prolonged infusion of DFP-10917, a deoxycytidine analog, as a therapeutic strategy for the treatment of human tumor xenografts in vivo

Kenzo Iizuka, Chun Zhang, Kokoro Eshima, Cheng Jin, Kiyoshi Eshima, Masakazu Fukushima

Pages: 851-860 Published online on: 16 January 2018

RNF113A promotes the proliferation, migration and invasion, and is associated with a poor prognosis of esophageal squamous cell carcinoma

Lei Wang, Zhichao Hou, Ayshamgul Hasim, Abulajiang Abuduerheman, Haiping Zhang, Madiniyat Niyaz, Idiris Awut, Halmurat Upur, Ilyar Sheyhidin

Pages: 861-871 Published online on: 24 January 2018

Connexin 43 SUMOylation improves gap junction functions between liver cancer stem cells and enhances their sensitivity to HSVtk/GCV

Yimeng Shen, Yanxia Li, Xiaofang Ma, Qiaohao Wan, Zhongmin Jiang, Yixin Liu, Dianying Zhang, Xiaozhi Liu, Wenhan Wu

Pages: 872-880 Published online on: 01 February 2018

Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species

Misa Yokoyama, Nobuhiro Tanuma, Rie Shibuya, Takeharu Shiroki, Makoto Abue, Kuniharu Yamamoto, Koh Miura, Kazunori Yamaguchi, Ikuro Sato, Keiichi Tamai, Kennichi Satoh

Pages: 881-891 Published online on: 30 January 2018

Endoglin (CD105) and SMAD4 regulate spheroid formation and the suppression of the invasive ability of human pancreatic cancer cells

Eri Kokaji, Akiko Shimomura, Takashi Minamisaka, Takahiko Nakajima, Shigeharu Miwa, Hideki Hatta, Takeshi Nishida, Chieko Kiya, Johji Imura

Pages: 892-900 Published online on: 01 February 2018

Long non-coding RNA H1 promotes cell proliferation and invasion by acting as a ceRNA of miR‑138 and releasing EZH2 in oral squamous cell carcinoma

Yonglong Hong, Haitao He, Wen Sui, Jingge Zhang, Shenfu Zhang, Dajiang Yang

Pages: 901-912 Published online on: 16 January 2018

Downregulation of matrix metalloproteinase 14 by the antitumor miRNA, miR-150-5p, inhibits the aggressiveness of lung squamous cell carcinoma cells

Takayuki Suetsugu, Keiichi Koshizuka, Naohiko Seki, Keiko Mizuno, Atsushi Okato, Takayuki Arai, Shunsuke Misono, Akifumi Uchida, Tomohiro Kumamoto, Hiromasa Inoue

Pages: 913-924 Published online on: 21 December 2017

Anticancer activity of the supercritical extract of Brazilian green propolis and its active component, artepillin C: Bioinformatics and experimental analyses of its mechanisms of action

Priyanshu Bhargava, Abhinav Grover, Nupur Nigam, Ashish Kaul, Motomichi Doi, Yoshiyuki Ishida, Hanzo Kakuta, Sunil C. Kaul, Keiji Terao, Renu Wadhwa

Pages: 925-932 Published online on: 22 January 2018

Alpha gene upregulates TFEB expression in renal cell carcinoma with t(6;11) translocation, which promotes cell canceration

He-Qin Zhan, Shu-Ting Li, Yan Shu, Meng-Meng Liu, Rong Qin, Yan-Li Li, Lin Gan

Pages: 933-944 Published online on: 05 January 2018

PFKFB3 is involved in breast cancer proliferation, migration, invasion and angiogenesis

Fang Peng, Qiang Li, Jia-Yuan Sun, Ying Luo, Ming Chen, Yong Bao

Pages: 945-954 Published online on: 30 January 2018

Identification of significant biomarkers and pathways associated with gastric carcinogenesis by whole genome-wide expression profiling analysis

Hong-Jun Fei, Song-Chang Chen, Jun-Yu Zhang, Shu-Yuan Li, Lan-Lan Zhang, Yi-Yao Chen, Chun-Xin Chang, Chen-Ming Xu

Pages: 955-966 Published online on: 11 January 2018

Characterisation of the p53 pathway in cell lines established from TH-MYCN transgenic mouse tumours

Lindi Chen, Arman Esfandiari, William Reaves, Annette Vu, Michael D. Hogarty, John Lunec, Deborah A. Tweddle

Pages: 967-977 Published online on: 31 January 2018

Expression of DNA damage response proteins in gastric cancer: Comprehensive protein profiling and histological analysis

Hiroki Arai, Ryuichi Wada, Kousuke Ishino, Mitsuhiro Kudo, Eiji Uchida, Zenya Naito

Pages: 978-988 Published online on: 05 January 2018

Ammonium tetrathiomolybdate enhances the antitumor effects of cetuximab via the suppression of osteoclastogenesis in head and neck squamous carcinoma

Ayaka Morisawa, Tatsuo Okui, Tsuyoshi Shimo, Soichiro Ibaragi, Yuka Okusha, Mitsuaki Ono, Thi Thu Ha Nguyen, Nur Mohammad Monsur Hassan, Akira Sasaki

Pages: 989-999 Published online on: 10 January 2018

Deoxycytidine kinase participates in the regulation of radiation-induced autophagy and apoptosis in breast cancer cells

Rui Zhong, Bing Liang, Rui Xin, Xuanji Zhu, Zhuo Liu, Qiao Chen, Yufei Hou, Zhao Jin, Mu Qi, Shumei Ma, Xiaodong Liu

Pages: 1000-1010 Published online on: 22 January 2018

Piperlongumine rapidly induces the death of human pancreatic cancer cells mainly through the induction of ferroptosis

Yuki Yamaguchi, Takashi Kasukabe, Shunichi Kumakura

Pages: 1011-1022 Published online on: 31 January 2018

Reduced-gliotoxin induces ROS-mediated anoikis in human colorectal cancer cells

Junxiong Chen, Qiong Lou, Lu He, Chuangyu Wen, Mengmeng Lin, Zefeng Zhu, Fang Wang, Lanlan Huang, Wenjian Lan, Aikichi Iwamoto, Xiangling Yang, Huanliang Liu

Pages: 1023-1032 Published online on: 01 February 2018
Journal Cover

Cover Legend PDF

March 2018
Volume 52 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2016 Impact Factor: 3.079
Ranked #33/217 Oncology
(total number of cites)

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