Journal Articles

Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)

Xu Zhang, Wen Zhang, Xiao Yuan, Min Fu, Hui Qian, Wenrong Xu

Pages: 857-867 Published online on: 07 July 2016
Open Access

Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors

Makoto Nakakido, Kenji Tamura, Suyoun Chung, Koji Ueda, Risa Fujii, Kazuma Kiyotani, Yusuke Nakamura

Pages: 868-876 Published online on: 06 July 2016
Open Access

Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells

Hiroshi Yamada, Tetsuya Takeda, Hiroyuki Michiue, Tadashi Abe, Kohji Takei

Pages: 877-886 Published online on: 30 June 2016
Open Access

Enhanced expression of semaphorin 3E is involved in the gastric cancer development

Ryuhei Maejima, Keiichi Tamai, Takeharu Shiroki, Misa Yokoyama, Rie Shibuya, Mao Nakamura, Kazunori Yamaguchi, Makoto Abue, Tomoyuki Oikawa, Tetsuya Noguchi, Koh Miura, Tsuneaki Fujiya, Ikuro Sato, Katsunori Iijima, Tooru Shimosegawa, Nobuyuki Tanaka, Kennichi Satoh

Pages: 887-894 Published online on: 30 June 2016
Open Access

Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice

John Cha, M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath

Pages: 895-902 Published online on: 01 July 2016
Open Access

Overexpression of KH-type splicing regulatory protein regulates proliferation, migration, and implantation ability of osteosarcoma

Dumnoensun Pruksakorn, Pimpisa Teeyakasem, Jeerawan Klangjorhor, Parunya Chaiyawat, Jongkolnee Settakorn, Penchatr Diskul-Na-Ayudthaya, Daranee Chokchaichamnankit, Peraphan Pothacharoen, Chantragan Srisomsap

Pages: 903-912 Published online on: 04 July 2016
Open Access

Protein signatures as potential surrogate biomarkers for stratification and prediction of treatment response in chronic myeloid leukemia patients

Ayodele A. Alaiya, Mahmoud Aljurf, Zakia Shinwari, Fahad Almohareb, Hafiz Malhan, Hazzaa Alzahrani, Tarek Owaidah, Jonathan Fox, Fahad Alsharif, Said Y. Mohamed, Walid Rasheed, Ghuzayel Aldawsari, Amr Hanbali, Syed Osman Ahmed, Naeem Chaudhri

Pages: 913-933 Published online on: 07 July 2016

Neuromedin B receptor antagonism inhibits migration, invasion, and epithelial-mesenchymal transition of breast cancer cells

Hyun-Joo Park, Mi-Kyoung Kim, Kyu-Sil Choi, Joo-Won Jeong, Soo-Kyung Bae, Hyung Joon Kim, Moon-Kyoung Bae

Pages: 934-942 Published online on: 30 June 2016

Long non-coding RNA HOTAIR modulates HLA-G expression by absorbing miR-148a in human cervical cancer

Jinbao Sun, Haipeng Chu, Jianghai Ji, Gaoxiang Huo, Qinglei Song, Xue Zhang

Pages: 943-952 Published online on: 30 June 2016

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

Kateřina Vlčková, Jiri Réda, Lubica Ondrušová, Mohammad Krayem, Ghanem Ghanem, Jiri Vachtenheim

Pages: 953-960 Published online on: 01 July 2016

SPECT imaging of neuropilin receptor type-1 expression with 131I-labeled monoclonal antibody

Xiaofeng Dou, Jianghua Yan, Yafei Zhang, Peng Liu, Yizhen Jiang, Sha Lv, Fanwei Zeng, Xiaoli Chen, Shengyu Wang, Haipeng Zhang, Hua Wu, Hong Zhang, Lin Ouyang, Xinhui Su

Pages: 961-970 Published online on: 16 June 2016

Sustainable inflammation transforms hepatic cells by causing oxidative stress injury and potential epithelial-mesenchymal transition

Kun Lu, Guoyan Liu, Ling Yang, Fan Liu, Libin Gao, Jingxian Shi, Xiaoling Deng, Qifu Li, Donghui Xu, Songlin Shi

Pages: 971-980 Published online on: 16 June 2016

Lentivirus-mediated downregulation of MAT2B inhibits cell proliferation and induces apoptosis in melanoma

Yu Lei, Bo Zhang, Yaohua Zhang, Yuan Zhao, Jingying Sun, Xuejun Zhang, Sen Yang

Pages: 981-990 Published online on: 05 July 2016

Association between cancer stem cell-like properties and epithelial-to-mesenchymal transition in primary and secondary cancer cells

Wonbong Lim, Hye-Eun Kim, Young Kim, Risu Na, Xiaojie Li, Sangmi Jeon, Hongran Choi, Okjoon Kim

Pages: 991-1000 Published online on: 16 June 2016

SPOP promotes tumor progression via activation of β-catenin/TCF4 complex in clear cell renal cell carcinoma

Wencai Zhao, Jiancheng Zhou, Zhuo Deng, Yang Gao, Yongyi Cheng

Pages: 1001-1008 Published online on: 06 July 2016

Baicalein induces apoptosis via ROS-dependent activation of caspases in human bladder cancer 5637 cells

Eun-Ok Choi, Cheol Park, Hye-Jin Hwang, Su Hyun Hong, Gi-Young Kim, Eun-Ju Cho, Wun-Jae Kim, Yung Hyun Choi

Pages: 1009-1018 Published online on: 06 July 2016

Curcumin inhibits invasive capabilities through epithelial mesenchymal transition in breast cancer cell lines

Marcela Gallardo, Gloria M. Calaf

Pages: 1019-1027 Published online on: 04 July 2016

Silencing Aurora-A with siRNA inhibits cell proliferation in human lung adenocarcinoma cells

Ning Zhong, Shunbin Shi, Hongzhen Wang, Guangzhou Wu, Yunliang Wang, Qiang Ma, Hongwei Wang, Yuanhua Liu, Jinzhi Wang

Pages: 1028-1038 Published online on: 05 July 2016

The novel mTORC1/2 dual inhibitor INK128 enhances radiosensitivity of breast cancer cell line MCF-7

Zhi-Gang Liu, Jiao Tang, Zhenghu Chen, Huiyuan Zhang, Hui Wang, Jianhua Yang, Hong Zhang

Pages: 1039-1045 Published online on: 05 July 2016

TSC22D2 interacts with PKM2 and inhibits cell growth in colorectal cancer

Fang Liang, Qiao Li, Xiayu Li, Zheng Li, Zhaojian Gong, Hao Deng, Bo Xiang, Ming Zhou, Xiaoling Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong

Pages: 1046-1056 Published online on: 04 July 2016

Heterogeneous expression of zinc-finger E-box-binding homeobox 1 plays a pivotal role in metastasis via regulation of miR-200c in epithelial-mesenchymal transition

Yuta Muto, Koichi Suzuki, Takaharu Kato, Shingo Tsujinaka, Kosuke Ichida, Yuji Takayama, Taro Fukui, Nao Kakizawa, Fumiaki Watanabe, Masaaki Saito, Kazushige Futsuhara, Hiroshi Noda, Yasuyuki Miyakura, Fumio Konishi, Toshiki Rikiyama

Pages: 1057-1067 Published online on: 17 June 2016

MicroRNA-224 aggrevates tumor growth and progression by targeting mTOR in gastric cancer

Ying Zhang, Chang-Feng Li, Lian-Jun Ma, Meng Ding, Bin Zhang

Pages: 1068-1080 Published online on: 16 June 2016

A 3-dimensional DTI MRI-based model of GBM growth and response to radiation therapy

Leith Hathout, Vishal Patel, Patrick Wen

Pages: 1081-1087 Published online on: 01 July 2016

Immunological effects of the anti-programmed death-1 antibody on human peripheral blood mononuclear cells

Yasuto Akiyama, Chizu Nonomura, Ryota Kondou, Haruo Miyata, Tadashi Ashizawa, Chie Maeda, Koichi Mitsuya, Nakamasa Hayashi, Yoko Nakasu, Ken Yamaguchi

Pages: 1099-1107 Published online on: 29 June 2016

Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs

Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao

Pages: 1108-1118 Published online on: 30 June 2016

The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma

Ichiro Fukumoto, Keiichi Koshizuka, Toyoyuki Hanazawa, Naoko Kikkawa, Ryosuke Matsushita, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Yoshitaka Okamoto, Naohiko Seki

Pages: 1119-1129 Published online on: 04 July 2016

Anti-EGFR immunonanoparticles containing IL12 and salmosin genes for targeted cancer gene therapy

Jung Seok Kim, Seong Jae Kang, Hwa Yeon Jeong, Min Woo Kim, Sang Il Park, Yeon Kyung Lee, Hong Sung Kim, Keun Sik Kim, Yong Serk Park

Pages: 1130-1138 Published online on: 07 July 2016

The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling

Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Yiguan Zhang, Jiajiu Shaw, Frederick A. Valeriote, Subhash C. Gautam

Pages: 1139-1147 Published online on: 29 June 2016

Eupatilin inhibits EGF-induced JB6 cell transformation by targeting PI3K

Feng Li, Ya Tao, Yan Qiao, Ke Li, Yanan Jiang, Chang Cao, Shuxin Ren, Xiaobin Chang, Xiaona Wang, Yanhong Wang, Yifei Xie, Ziming Dong, Jimin Zhao, Kangdong Liu

Pages: 1148-1154 Published online on: 04 July 2016

MicroRNA-195 targets VEGFR2 and has a tumor suppressive role in ACHN cells via PI3K/Akt and Raf/MEK/ERK signaling pathways

Pengcheng Sun, Lu Wang, Yunhan Lu, Yuwei Liu, Lechen Li, Luyao Yin, Cheng Zhang, Weiming Zhao, Baozhong Shen, Wanhai Xu

Pages: 1155-1163 Published online on: 06 July 2016

Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor

Simona Caporali, Ester Alvino, Pedro Miguel Lacal, Lauretta Levati, Giorgio Giurato, Domenico Memoli, Elisabetta Caprini, Gian Carlo Antonini Cappellini, Stefania D'Atri

Pages: 1164-1174 Published online on: 30 June 2016

FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer

Karolina H. Czarnecka, Monika Migdalska-Sęk, Daria Domańska, Dorota Pastuszak-Lewandoska, Agata Dutkowska, Jacek Kordiak, Ewa Nawrot, Justyna Kiszałkiewicz, Adam Antczak, Ewa Brzeziańska-Lasota

Pages: 1175-1184 Published online on: 06 July 2016

Influence of molecular design on biodistribution and targeting properties of an Affibody-fused HER2-recognising anticancer toxin

Mohamed Altai, Hao Liu, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund

Pages: 1185-1194 Published online on: 06 July 2016

Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer

Mitsuro Kanda, Dai Shimizu, Tsutomu Fujii, Haruyoshi Tanaka, Masahiro Shibata, Naoki Iwata, Masamichi Hayashi, Daisuke Kobayashi, Chie Tanaka, Suguru Yamada, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera

Pages: 1195-1202 Published online on: 17 June 2016

Genistein targets the cancerous inhibitor of PP2A to induce growth inhibition and apoptosis in breast cancer cells

Qingxia Zhao, Ming Zhao, Amanda B. Parris, Ying Xing, Xiaohe Yang

Pages: 1203-1210 Published online on: 30 June 2016

Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells

Hisashi Masuyama, Keiichiro Nakamura, Etsuko Nobumoto, Yuji Hiramatsu

Pages: 1211-1220 Published online on: 06 July 2016

An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway

Nurfarhanah Bte Syed Sulaiman, Chakrabhavi Dhananjaya Mohan, Basappa, Vijay Pandey, Shobith Rangappa, Hanumantharayappa Bharathkumar, Alan Prem Kumar, Peter E. Lobie, Kanchugarakoppal S. Rangappa

Pages: 1221-1229 Published online on: 06 July 2016

Suppression of MMP-9 and FAK expression by pomolic acid via blocking of NF-κB/ERK/mTOR signaling pathways in growth factor-stimulated human breast cancer cells

Ji-Hyun Park, Yoon Young Cho, Seong Woo Yoon, Byoungduck Park

Pages: 1230-1240 Published online on: 29 June 2016

Induction of TTF-1 or PAX-8 expression on proliferation and tumorigenicity in thyroid carcinomas

Célia Dupain, Hafiz M. Ali, Tarik Ait Mouhoub, Giorgia Urbinati, Liliane Massaad-Massade

Pages: 1248-1258 Published online on: 07 July 2016
Open Access

[Corrigendum] Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced rats

Yuki Fujise, Jun-Ichi Okano, Takakazu Nagahara, Ryo Abe, Ryu Imamoto, Yoshikazu Murawaki

Pages: 1259-1259 Published online on: 15 June 2016
Open Access

[Corrigendum] Cisplatin in combination with zoledronic acid: A synergistic effect in triple-negative breast cancer cell lines

Toni Ibrahim, Chiara Liverani, Laura Mercatali, Emanuele Sacanna, Michele Zanoni, Francesco Fabbri, Wainer Zoli, Dino Amadori

Pages: 1260-1260 Published online on: 06 July 2016
Journal Cover

Cover Legend PDF

September 2016
Volume 49 Issue 3

Print ISSN: 1019-6439
Online ISSN: 1791-2423

2015 Impact Factor: 3.018
Ranked #30/211 Oncology
(total number of cites)

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