Journal Articles

Open Access

LETM1 is required for mitochondrial homeostasis and cellular viability (Review)

Yuwen Li, Quangdon Tran, Robin Shrestha, Longzhen Piao, Sungjin Park, Jisoo Park, Jongsun Park

Pages: 3367-3375 Published online on: 15 March 2019
Open Access

Identification of exosomal and non‑exosomal microRNAs associated with the drug resistance of ovarian cancer

Yiwen Feng, Wenzhao Hang, Zhenyu Sang, Shuangdi Li, Wei Xu, Yi Miao, Xiaowei Xi, Qian Huang

Pages: 3376-3392 Published online on: 05 March 2019
Open Access

MicroRNA‑4530 suppresses cell proliferation and induces apoptosis by targeting RASA1 in human umbilical vein endothelial cells

Li Jing, Hong Li, Tao Zhang, Jianxin Lu, Lianjin Zhong

Pages: 3393-3402 Published online on: 01 March 2019
Open Access

Effect of miR‑145 on gastric cancer cells

Jia Wang, Zheng Sun, Shihai Yan, Feng Gao

Pages: 3403-3410 Published online on: 06 March 2019
Open Access

Construction and dissection of the ceRNA‑ceRNA network reveals critical modules in depression

Yan Lang, Jingchao Zhang, Zheng Yuan

Pages: 3411-3420 Published online on: 05 March 2019
Open Access

Long noncoding RNA expression profile and functional analysis in psoriasis

Jianjun Yan, Jie Song, Meng Qiao, Xintong Zhao, Ronghua Li, Jian Jiao, Qing Sun

Pages: 3421-3430 Published online on: 27 February 2019
Open Access

ACC1 is overexpressed in liver cancers and contributes to the proliferation of human hepatoma Hep G2 cells and the rat liver cell line BRL 3A

Bingyu Ye, Li Yin, Qiwen Wang, Cunshuan Xu

Pages: 3431-3440 Published online on: 27 February 2019
Open Access

Clinical diagnosis and genetic counseling of atypical ataxia‑telangiectasia in a Chinese family

Jiangxia Cao, Ruiqin Shen, Wenqian Zhang, Bing Mao, Qirong Shi, Rui Zhou, Zijing Liu, Bing Zeng, Xiaoling Chen, Cai Zhang, Min Lu, Peng Han, Jing Wu, Aifen Zhou, Xuemei Tan

Pages: 3441-3448 Published online on: 27 February 2019
Open Access

Protective effects of carbon monoxide releasing molecule‑2 on pancreatic function in septic mice

Yishu Liu, Xu Wang, Xiaohan Xu, Weiting Qin, Bingwei Sun

Pages: 3449-3458 Published online on: 18 March 2019
Open Access

c‑Jun/Ap‑1 is upregulated in an Ang II‑induced abdominal aortic aneurysm formation model and mediates Chop expression in mouse aortic smooth muscle cells

Dating Sun, Mingxi Zhang, Yuanyuan Li, Shuai Mei, Jin Qin, Jiangtao Yan

Pages: 3459-3468 Published online on: 12 March 2019
Open Access

ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis

Luna Ge, Yazhou Cui, Baoyan Liu, Xiaoli Yin, Jingxiang Pang, Jinxiang Han

Pages: 3469-3476 Published online on: 01 March 2019
Open Access

Diagnostic and prognostic value of CEP55 in clear cell renal cell carcinoma as determined by bioinformatics analysis

Libin Zhou, Shibo Liu, Xing Li, Min Yin, Sheng Li, Huimin Long

Pages: 3485-3496 Published online on: 15 March 2019
Open Access

Enhanced sensitivity of capture IgE‑ELISA based on a recombinant Der f 1/2 fusion protein for the detection of IgE antibodies targeting house dust mite allergens

Zhen Zhang, Zelang Cai, Yibo Hou, Jiayun Hu, Yongshen He, Jiajie Chen, Kunmei Ji

Pages: 3497-3504 Published online on: 18 March 2019
Open Access

TGF‑β1 promotes the osteoinduction of human osteoblasts via the PI3K/AKT/mTOR/S6K1 signalling pathway

Zhaodong Zhang, Xiuzhi Zhang, Dewei Zhao, Baoyi Liu, Benjie Wang, Weiting Yu, Junlei Li, Xiaobing Yu, Fang Cao, Guoshuang Zheng, Yao Zhang, Yupeng Liu

Pages: 3505-3518 Published online on: 18 March 2019
Open Access

Overexpression of ribonuclease inhibitor induces autophagy in human colorectal cancer cells via the Akt/mTOR/ULK1 pathway

Ying Tang, Feng Ren, Xi Cong, Ying Kong, Yuxiang Tian, Yuefei Xu, Jianhui Fan

Pages: 3519-3526 Published online on: 14 March 2019
Open Access

MicroRNA‑1 downregulation induced by carvedilol protects cardiomyocytes against apoptosis by targeting heat shock protein 60

Yingying Hu, Xi Chen, Xina Li, Zhange Li, Hongtao Diao, Lu Liu, Jia Zhang, Jin Ju, Lin Wen, Xin Liu, Zhenwei Pan, Chaoqian Xu, Xin Hai, Yong Zhang

Pages: 3527-3536 Published online on: 14 March 2019
Open Access

Astaxanthin inhibits proliferation and induces apoptosis of LX‑2 cells by regulating the miR‑29b/Bcl‑2 pathway

Shanshan Zhu, Tao Wang, Fei Luo, Huawen Li, Qing Jia, Taiping He, Hongfu Wu, Tangbin Zou

Pages: 3537-3547 Published online on: 14 March 2019
Open Access

Rhizoma Paridis saponins ameliorates hepatic fibrosis in rats by downregulating expression of angiogenesis‑associated growth factors

Yanquan Han, Lingyu Pan, Shan Ran, Yan Song, Fang‑Fang Sun, Yong‑Zhong Wang, Yan Hong

Pages: 3548-3554 Published online on: 05 March 2019
Open Access

Estrogen receptor β suppresses inflammation and the progression of prostate cancer

Long Xiao, Yaohui Luo, Rongfen Tai, Ningnan Zhang

Pages: 3555-3563 Published online on: 06 March 2019
Open Access

Expression analysis of transfer RNA‑derived fragments in the blood of patients with moyamoya disease: A preliminary study

Chengjun Wang, Meng Zhao, Jia Wang, Dong Zhang, Shuo Wang, Jizong Zhao

Pages: 3564-3574 Published online on: 14 March 2019
Open Access

miR‑145 suppresses ovarian cancer progression via modulation of cell growth and invasion by targeting CCND2 and E2F3

Minhui Hua, Yongwei Qin, Meihong Sheng, Xiaopeng Cui, Weiguan Chen, Jianxin Zhong, Junming Yan, Yan Chen

Pages: 3575-3583 Published online on: 05 March 2019
Open Access

A new combination of transcription factors increases the harvesting efficiency of pacemaker‑like cells

Jian Zhang, Congxin Huang

Pages: 3584-3592 Published online on: 06 March 2019
Open Access

Dose and drug changes in chronic lymphocytic leukemia cell response in vitro: A comparison of standard therapy regimens with two novel cyclin‑dependent kinase inhibitors

Małgorzata Kubczak, Aleksandra Szustka, Jerzy Z. Błoński, Tomaš Gucký, Małgorzata Misiewicz, Vladmir Krystof, Paweł Robak, Małgorzata Rogalińska

Pages: 3593-3603 Published online on: 05 March 2019
Open Access

miR‑512‑5p suppresses proliferation, migration and invasion, and induces apoptosis in non‑small cell lung cancer cells by targeting ETS1

Bin Cao, Sheng Tan, Huijuan Tang, Yihui Chen, Peng Shu

Pages: 3604-3614 Published online on: 14 March 2019
Open Access

LncRNA AWPPH promotes the proliferation, migration and invasion of ovarian carcinoma cells via activation of the Wnt/β‑catenin signaling pathway

Guangyu Yu, Wenshuang Wang, Junfeng Deng, Shaohua Dong

Pages: 3615-3621 Published online on: 14 March 2019
Open Access

Ginsenoside Rb1 attenuates intestinal ischemia/reperfusion‑induced inflammation and oxidative stress via activation of the PI3K/Akt/Nrf2 signaling pathway

Sufang Chen, Xiang Li, Yanling Wang, Panwei Mu, Chaojin Chen, Pinjie Huang, Dezhao Liu

Pages: 3633-3641 Published online on: 12 March 2019
Open Access

The antitumor function of arctigenin in human retinoblastoma cells is mediated by jagged‑1

Ning Ke, Qing Liu, Lianhong Pi, Jing Fang, Lin Chen, Xinke Chen

Pages: 3642-3648 Published online on: 14 March 2019
Open Access

Activation of the ERK/Creb/Bcl‑2 pathway protects periodontal ligament stem cells against hydrogen peroxide‑induced oxidative stress

Xiaohui Fu, Yimiao Feng, Bingyi Shao, Yanzhen Zhang

Pages: 3649-3657 Published online on: 14 March 2019
Open Access

Knockdown of serpin peptidase inhibitor clade C member 1 inhibits the growth of nasopharyngeal carcinoma cells

Jin Xu, Yin Ying, Gaoyun Xiong, Liqin Lai, Qingliang Wang, Yue Yang

Pages: 3658-3666 Published online on: 14 March 2019
Open Access

MicroRNA‑124 suppresses cell proliferation and invasion of triple negative breast cancer cells by targeting STAT3

Pengfei Shi, Cheng Chen, Xiang Li, Zhanjie Wei, Zhimin Liu, Yongjun Liu

Pages: 3667-3675 Published online on: 15 March 2019
Open Access

Vitamin K2 stimulates MC3T3‑E1 osteoblast differentiation and mineralization through autophagy induction

Weiwei Li, Shaokun Zhang, Jie Liu, Yongyi Liu, Qingwei Liang

Pages: 3676-3684 Published online on: 15 March 2019
Open Access

Prognostic role of Tif1γ expression and circulating tumor cells in patients with breast cancer

Fengfeng Cai, Lu Cai, Zhuchao Zhou, Xin Pan, Minghong Wang, Su Chen, Manuel Antonio Falar Luis, Chunmei Cen, Ewelina Biskup

Pages: 3685-3695 Published online on: 14 March 2019
Open Access

SDF‑1/CXCR4 induces epithelial‑mesenchymal transition through activation of the Wnt/β‑catenin signaling pathway in rat chronic allograft nephropathy

Hao Tang, Yue Xu, Zijian Zhang, Song Zeng, Wenbo Dong, Wenjiao Jiao, Xiaopeng Hu

Pages: 3696-3706 Published online on: 15 March 2019
Open Access

1,25‑Dihydroxy‑Vitamin D3 induces macrophage polarization to M2 by upregulating T‑cell Ig‑mucin‑3 expression

Shuyu Liang, Jinzhen Cai, Yani Li, Rui Yang

Pages: 3707-3713 Published online on: 15 March 2019
Open Access

circEIF4G2 modulates the malignant features of cervical cancer via the miR‑218/HOXA1 pathway

Yifan Mao, Liya Zhang, Yuan Li

Pages: 3714-3722 Published online on: 14 March 2019
Open Access

Hepatic miR‑215 target Rictor and modulation of hepatic insulin signalling in rats

Wei‑Dong Li, Jin‑Rong Xia, Yan‑Shu Lian

Pages: 3723-3731 Published online on: 14 March 2019
Open Access

Calcitonin gene‑related peptide regulates FOSL2 expression and cell proliferation of BMSCs via mmu_circRNA_003795

Wen Ren, Lan Yang, Tian Deng, Caijuan Wu, Yuanjing Li, Jingwen Wu, Zhu Huang, Faliang Du, Lvhua Guo

Pages: 3732-3742 Published online on: 14 March 2019
Open Access

β‑estradiol alleviates hypertension‑ and concanavalin A‑mediated inflammatory responses via modulation of connexins in peripheral blood lymphocytes

Xin Ni, Liang Zhang, Xin Ma, Li‑Ya Shan, Li Li, Jun‑Qiang Si, Xin‑Zhi Li, You‑Yi Zhang, Ke‑Tao Ma

Pages: 3743-3755 Published online on: 14 March 2019

Long noncoding RNA MALAT1 regulates sepsis in patients with burns by modulating miR‑214 with TLR5

Fengying Gao, Rong Chen, Yaofeng Xi, Qiujian Zhao, Haifeng Gao

Pages: 3756-3766 Published online on: 14 March 2019

Resveratrol is an arginase inhibitor contributing to vascular smooth muscle cell vasoconstriction via increasing cytosolic calcium

Chang Ik Choi, Bon Hyeock Koo, Dongeui Hong, Hyung Joo Kwon, Kwang Lae Hoe, Moo Ho Won, Young Myeong Kim, Hyun Kyo Lim, Sungwoo Ryoo

Pages: 3767-3774 Published online on: 14 March 2019

MicroRNA‑142‑3p inhibits trophoblast cell migration and invasion by disrupting the TGF‑β1/Smad3 signaling pathway

Enling Liu, Zheng Liu, Yuxiu Zhou, Mei Chen, Liqun Wang, Jun Li

Pages: 3775-3782 Published online on: 01 March 2019

Resveratrol improves cognition and decreases amyloid plaque formation in Tg6799 mice

Yue Chen, Guang‑Wei Shi, Zhi‑Man Liang, Shu‑Yue Sheng, Yu‑Sheng Shi, Li Peng, Ya‑Ping Wang, Fang Wang, Xing‑Mei Zhang

Pages: 3783-3790 Published online on: 06 March 2019

Protective effects of PNU‑282987 on sepsis‑induced acute lung injury in mice

Zhenzhen Shao, Quan Li, Shuang Wang, Zhixia Chen

Pages: 3791-3798 Published online on: 12 March 2019

EFLDO sensitizes liver cancer cells to TNFSF10‑induced apoptosis in a p53‑dependent manner

Yanbo Qu, Zhixin Liao, Xinzhu Wang, Jing Zhang, Chao Liu

Pages: 3799-3806 Published online on: 15 March 2019

miR‑124 regulates the osteogenic differentiation of bone marrow‑derived mesenchymal stem cells by targeting Sp7

Jia‑Zhen Tang, Xiao Lin, Jia‑Yu Zhong, Feng Xu, Feng Wu, Xiao‑Bo Liao, Rong‑Rong Cui, Fuxingzi Li, Ling‑Qing Yuan

Pages: 3807-3814 Published online on: 18 March 2019

Pioglitazone prevents sevoflurane‑induced neuroinflammation and cognitive decline in a rat model of chronic intermittent hypoxia by upregulating hippocampal PPAR‑γ

Xiyan Zhang, Ning Li, Lingling Lu, Quan Lin, Liang Li, Ping Dong, Bo Yang, Dongliang Li, Jianchun Fei

Pages: 3815-3822 Published online on: 18 March 2019

MicroRNA‑132 mediates proliferation and migration of pulmonary smooth muscle cells via targeting PTEN

Zhen‑Hua Zeng, Wei‑Hua Wu, Qi Peng, Ya‑Hui Sun, Jian‑Xin Liu

Pages: 3823-3830 Published online on: 18 March 2019

Targeted next‑generation sequencing for research and diagnostics in congenital heart disease, and cleft lip and/or palate

Haisong Bu, Lin Liu, Shijun Hu, Zhiping Tan, Tianli Zhao

Pages: 3831-3840 Published online on: 15 March 2019

Aurora kinase inhibitor VX‑680 suppresses the proliferation and migration of HUVECs and angiogenesis

Xuejiao Sun, Shishi Niu, Zhen Zhang, Anyan Wang, Chengyuan Yang, Zichan Guo, Yuepeng Hao, Xiaozhong Li, Xiaoxia Wang

Pages: 3841-3847 Published online on: 27 February 2019

The role of ethanol in the pathogenesis of non‑bacterial prostatitis

Feng Liu, Lintao Liu, Zhong Wang, Lin Chen, Jianjun Yu, Xiaolin Xu

Pages: 3848-3854 Published online on: 27 February 2019

Genome‑wide profiling of lncRNA and mRNA expression in CRSwNP

Minglei Liu, Ping Guo, Jun An, Chao Guo, Fengxiang Lu, Yanhua Lei

Pages: 3855-3863 Published online on: 05 March 2019

Effect of docetaxel on the regulation of proliferation and apoptosis of human prostate cancer cells

Chongyi Yang, Weijie Zhang, Jie Wang, Pengpeng Chen, Jiangjiang Jin

Pages: 3864-3870 Published online on: 01 March 2019
Open Access

Identification of hub genes in chronically hypoxic myocardium using bioinformatics analysis

Fan Wu, Feng Gao, Siyi He, Yingbin Xiao

Pages: 3871-3881 Published online on: 01 March 2019

MicroRNA‑122 downregulates Rho‑associated protein kinase 2 expression and inhibits the proliferation of prostate carcinoma cells

Hong Liu, Teng Hou, Wen Ju, Yifei Xing, Xiaoping Zhang, Jun Yang

Pages: 3882-3888 Published online on: 27 February 2019

Preparation of a monoclonal antibody against the carcinoembryonic antigen, glypican‑3

Yongdong Zhang, Dongri Qiu, Ronghua Li, Yawu Liu, Shuainan Shi, Yuliang Wang

Pages: 3889-3895 Published online on: 13 March 2019

MicroRNA‑663b downregulation inhibits proliferation and induces apoptosis in bladder cancer cells by targeting TUSC2

Jianying Chen, Bo Song, Guangqi Kong

Pages: 3896-3902 Published online on: 14 March 2019

Expression of steroidogenic enzymes in human placenta according to the gestational age

So‑Hye Hong, Seung Chul Kim, Mee‑Na Park, Jea Sic Jeong, Seung Yun Yang, Young Joo Lee, Ok‑Nam Bae, Hoe‑Saeng Yang, Sungbaek Seo, Kyu‑Sup Lee, Beum‑Soo An

Pages: 3903-3911 Published online on: 15 March 2019

CircRNA‑0044073 is upregulated in atherosclerosis and increases the proliferation and invasion of cells by targeting miR‑107

Lin Shen, Yanyan Hu, Jianwei Lou, Sen Yin, Weiling Wang, Yuanyan Wang, Yong Xia, Wei Wu

Pages: 3923-3932 Published online on: 06 March 2019

MicroRNA‑708 inhibits the proliferation and invasion of osteosarcoma cells by directly targeting ZEB1

Jun He, Deng Xiang, Yanshui Lin

Pages: 3948-3954 Published online on: 06 March 2019
Open Access

[Retracted] Generation and characterization of induced pluripotent stem cells from guinea pig fetal fibroblasts

Yuehong Wu, Ouyang Li, Chengwen He, Yong Li, Min Li, Xiaoming Liu, Yujiong Wang, Yulong He

Pages: 3955-3955 Published online on: 13 March 2019
Open Access

[Erratum] Chemoresistance‑related long non‑coding RNA expression profiles in human breast cancer cells

Lei Huang, Lihua Zeng, Jiahui Chu, Pengfei Xu, Mingming Lv, Juan Xu, Juan Wen, Wenqu Li, Luyu Wang, Xiaowei Wu, Ziyi Fu, Hui Xie, Shui Wang

Pages: 3956-3956 Published online on: 01 March 2019
Open Access

Regulation of histone arginine methylation/demethylation by methylase and demethylase (Review)

Jing Zhang, Li Jing, Menghan Li, Lingfeng He, Zhigang Guo

Pages: 3963-3971 Published online on: 01 April 2019
Open Access

Differential urinary proteomics analysis of myocardial infarction using iTRAQ quantification

Lili Zou, Xubo Wang, Zhengguang Guo, Haidan Sun, Chen Shao, Yehong Yang, Wei Sun

Pages: 3972-3988 Published online on: 26 March 2019
Open Access

Comparative analysis of gene expression profiles in children with type 1 diabetes mellitus

Liwei Qian, Honglei Shi, Meili Ding

Pages: 3989-4000 Published online on: 28 March 2019
Open Access

The function of miRNA‑153 against isoflurane‑induced neurotoxicity via Nrf2/ARE cytoprotection

Dong Shao, Zhouquan Wu, Shuying Bai, Guowei Fu, Zhiqing Zou

Pages: 4001-4010 Published online on: 19 March 2019
Open Access

Rebamipide ophthalmic solution modulates the ratio of T helper cell 17/regulatory T cells in dry eye disease mice

Rongrong Fu, Yanhua Jiang, Jing Zhou, Jinsong Zhang

Pages: 4011-4018 Published online on: 21 March 2019
Open Access

Ginsenoside Rg5 induces apoptosis in human esophageal cancer cells through the phosphoinositide‑3 kinase/protein kinase B signaling pathway

Daoming Zhang, Aifu Wang, Jueping Feng, Qi Zhang, Linlin Liu, Hui Ren

Pages: 4019-4026 Published online on: 27 March 2019
Open Access

Upregulation of microRNA‑16 alters the response to inhaled β‑agonists in patients with asthma though modulating expression of ADRB2

Bo Yu, Lusu Yao, Cuiqiao Liu, Lina Tang, Tao Xing

Pages: 4027-4034 Published online on: 28 March 2019
Open Access

Inhibition of miR‑214 attenuates the migration and invasion of triple‑negative breast cancer cells

Yi Zhang, Zhijing Zhao, Siqi Li, Liying Dong, Yan Li, Ying Mao, Ying Liang, Yun Tao, Junfeng Ma

Pages: 4035-4042 Published online on: 01 April 2019
Open Access

Characterization of different biodegradable scaffolds in tissue engineering

Yan‑Ling Qiu, Xiao Chen, Ya‑Li Hou, Yan‑Juan Hou, Song‑Bo Tian, Yu‑He Chen, Li Yu, Min‑Hai Nie, Xu‑Qian Liu

Pages: 4043-4056 Published online on: 21 March 2019
Open Access

Targeting bacterial quorum sensing shows promise in improving intestinal barrier function following burn‑site infection

Fatemeh Adiliaghdam, Marianna Almpani, Mohammad Hadi Gharedaghi, Mehran Najibi, Richard A. Hodin, Laurence G. Rahme

Pages: 4057-4066 Published online on: 21 March 2019
Open Access

Screening of important lncRNAs associated with the prognosis of lung adenocarcinoma, based on integrated bioinformatics analysis

Jianliang Li, Xiaoping Yu, Qian Liu, Shuangyan Ou, Ke Li, Yi Kong, Hanchun Liu, Yongzhong Ouyang, Ruocai Xu

Pages: 4067-4080 Published online on: 19 March 2019
Open Access

Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye

Pages: 4081-4090 Published online on: 20 March 2019
Open Access

Autophagy alleviates the decrease in proliferation of amyloid β1‑42‑treated bone marrow mesenchymal stem cells via the AKT/mTOR signaling pathway

Bo Yang, Zhenyu Cai, Weilin Zhang, Dali Yin, Wei Zhao, Maowei Yang

Pages: 4091-4100 Published online on: 21 March 2019
Open Access

FOXM1 is a novel predictor of recurrence in patients with oral squamous cell carcinoma associated with an increase in epithelial‑mesenchymal transition

Ya‑Dong Luo, Xu Ding, Hong‑Ming Du, Yu‑Nong Wu, Huai‑Qi Li, He‑Ming Wu, Xiao‑Min Zhang

Pages: 4101-4108 Published online on: 27 March 2019
Open Access

Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure

Xiu‑Jing Zhang, Hua Tan, Zhi‑Fang Shi, Na Li, Ying Jia, Zhe Hao

Pages: 4109-4118 Published online on: 22 March 2019
Open Access

The anticancer effects of cinobufagin on hepatocellular carcinoma Huh‑7 cells are associated with activation of the p73 signaling pathway

Lei Zhao, Lina Fu, Zhongwei Xu, Rong Fan, Ruicheng Xu, Rong Fu, Shuang Zou, Congcong Wang, Yan Zhang, Jiabao Wang, Jun Bao, Zhimei Wang, Xiaojie Hou, Yupiao Zheng, Erqing Dai, Fengmei Wang

Pages: 4119-4128 Published online on: 29 March 2019
Open Access

Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species

Ying Pi, Haifeng Liang, Qiang Yu, Yukun Yin, Haixia Xu, Yutian Lei, Zhongyu Han, Jing Tian

Pages: 4129-4136 Published online on: 22 March 2019
Open Access

miR‑329‑3p regulates neural stem cell proliferation by targeting E2F1

Dapeng Lin, Yao Shi, Yiwen Hu, Xiaowen Du, Guanjun Tu

Pages: 4137-4146 Published online on: 28 March 2019
Open Access

Mutational spectrum and associations with clinical features in patients with acute myeloid leukaemia based on next‑generation sequencing

Ying Li, Xiao Lv, Xueling Ge, Dai Yuan, Mei Ding, Changqing Zhen, Wenbo Zhao, Xin Liu, Xianghua Wang, Hongzhi Xu, Ying Li, Xin Wang

Pages: 4147-4158 Published online on: 22 March 2019
Open Access

Production of an aberrant splice variant of CCL5 is not caused by genetic mutation in the mammary glands of mastitis‑infected Holstein cows

Ling Yang, Ruiqing Guo, Zhihua Ju, Xiuge Wang, Qiang Jiang, Yong Liu, Han Zhao, Kaili He, Jianbin Li, Jinming Huang

Pages: 4159-4166 Published online on: 28 March 2019
Open Access

Revealing the interaction between intrauterine adhesion and vaginal microbiota using high‑throughput sequencing

Zhaoxia Liu, Yao Kong, Yuan Gao, Yimeng Ren, Cihua Zheng, Xiaorong Deng, Tingtao Chen

Pages: 4167-4174 Published online on: 27 March 2019
Open Access

Identification and functional analysis of microRNAs in rats following focal cerebral ischemia injury

Xianchun Duan, Jianghua Gan, Dai‑Yin Peng, Qiuyu Bao, Ling Xiao, Liangbing Wei, Jian Wu

Pages: 4175-4184 Published online on: 21 March 2019
Open Access

Prenatal nicotine exposure induces depression‑like behavior in adolescent female rats via modulating neurosteroid in the hippocampus

Chong Zhang, Si‑Jing Fan, An‑Bang Sun, Zhen‑Zhen Liu, Lian Liu

Pages: 4185-4194 Published online on: 29 March 2019
Open Access

CBX3 predicts an unfavorable prognosis and promotes tumorigenesis in osteosarcoma

Chao Ma, Xing‑Guo Nie, Yan‑Li Wang, Xiang‑Hua Liu, Xue Liang, Qing‑Lan Zhou, Da‑Peng Wu

Pages: 4205-4212 Published online on: 28 March 2019
Open Access

MicroRNA‑25/ATXN3 interaction regulates human colon cancer cell growth and migration

Dingyun Li, Tao Zhang, Jiajun Lai, Jian Zhang, Ting Wang, Yafei Ling, Shengquan He, Zhiwei Hu

Pages: 4213-4221 Published online on: 27 March 2019
Open Access

TGF‑β1 upregulates the expression of lncRNA‑ATB to promote atherosclerosis

Huapeng Yu, Shengting Ma, Ling Sun, Jing Gao, Chengjun Zhao

Pages: 4222-4228 Published online on: 29 March 2019
Open Access

Let‑7a‑5p may participate in the pathogenesis of diabetic nephropathy through targeting HMGA2

Tao Wang, Hua Zhu, Shufang Yang, Xiaoqiang Fei

Pages: 4229-4237 Published online on: 19 March 2019
Open Access

Circulating NK cell subsets and NKT‑like cells in renal transplant recipients with acute T‑cell‑mediated renal allograft rejection

Xiaoguang Xu, Yong Han, Haiyan Huang, Lili Bi, Xiangrui Kong, Xihui Ma, Bingyi Shi, Li Xiao

Pages: 4238-4248 Published online on: 27 March 2019
Open Access

Pharmacological inhibition of EZH2 combined with DNA‑damaging agents interferes with the DNA damage response in MM cells

Li Xu, Hailong Tang, Kai Wang, Yanhua Zheng, Juan Feng, Hongjuan Dong, Yulong Jin, Chun Cao, Xiequn Chen, Guangxun Gao

Pages: 4249-4255 Published online on: 21 March 2019
Open Access

Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF‑7 breast cancer cells

Jie Li, Min‑Hua Rong, Yi‑Wu Dang, Rong‑Quan He, Peng Lin, Hong Yang, Xiao‑Jiao Li, Dan‑Dan Xiong, Li‑Jie Zhang, Hui Qin, Cai‑Xia Feng, Xiao‑Yi Chen, Jin‑Cai Zhong, Jie Ma, Gang Chen

Pages: 4256-4270 Published online on: 19 March 2019
Open Access

miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN

Si Zhang, Kang He, Weiwei Zhou, Jun Cao, Zuolin Jin

Pages: 4288-4296 Published online on: 26 March 2019
Open Access

The role of lateral pterygoid muscle in the traumatic temporomandibular joint ankylosis: A gene chip based analysis

Jianying Zhang, Xiangzhao Sun, Sen Jia, Xin Jiang, Tiange Deng, Ping Liu, Kaijin Hu

Pages: 4297-4305 Published online on: 22 March 2019
Open Access

Identification of potential diagnostic biomarkers for pneumonia caused by adenovirus infection in children by screening serum exosomal microRNAs

Feng Huang, Jun Bai, Junsong Zhang, Diyuan Yang, Huifeng Fan, Li Huang, Tingting Shi, Gen Lu

Pages: 4306-4314 Published online on: 29 March 2019
Open Access

High expression of B7‑H2 or B7‑H3 is associated with poor prognosis in hepatocellular carcinoma

Youshi Zheng, Naishun Liao, Yuan Wu, Ju Gao, Zhenli Li, Wenwen Liu, Yingchao Wang, Ming Li, Xiaolou Li, Li Chen, Wenmin Zhang, Bixing Zhao

Pages: 4315-4325 Published online on: 22 March 2019
Open Access

Exposure to polycyclic aromatic hydrocarbons derived from vehicle exhaust gas induces premature senescence in mouse lung fibroblast cells

Feng Yu, Ke Ye, Yunfeng Hu, Jincheng Li, Yonglei An, Dawei Qu

Pages: 4326-4334 Published online on: 26 March 2019
Open Access

Shikonin inhibits proliferation and induces apoptosis in glioma cells via downregulation of CD147

Na Guo, Rui Miao, Xingchun Gao, Dong Huang, Zhifang Hu, Naichun Ji, Ying Nan, Fengliang Jiang, Xingchun Gou

Pages: 4335-4343 Published online on: 28 March 2019
Open Access

Bioinformatics analysis of the prognostic value of CCT6A and associated signalling pathways in breast cancer

Kai Huang, Yi Zeng, Yunqing Xie, Liying Huang, Yu Wu

Pages: 4344-4352 Published online on: 28 March 2019
Open Access

Role of TLR‑4 in anti‑β2‑glycoprotein I‑induced activation of peritoneal macrophages and vascular endothelial cells in mice

Meiyun Wang, Xiangmin Kong, Yachao Xie, Chao He, Ting Wang, Hong Zhou

Pages: 4353-4363 Published online on: 26 March 2019
Open Access

A novel compound heterozygous mutation in SLC5A2 contributes to familial renal glucosuria in a Chinese family, and a review of the relevant literature

Shentang Li, Yeyi Yang, Lihua Huang, Min Kong, Zuocheng Yang

Pages: 4364-4376 Published online on: 01 April 2019
Open Access

Identification of suitable reference genes for gene expression studies in rat skeletal muscle following sciatic nerve crush injury

Xinghui Wang, Hualong Zhao, Jun Ni, Jiacheng Pan, Hao Hua, Yaxian Wang

Pages: 4377-4387 Published online on: 28 March 2019
Open Access

miR‑146a‑5p expression is upregulated by the CXCR4 antagonist TN14003 and attenuates SDF‑1‑induced cartilage degradation

Di Jia, Yanlin Li, Rui Han, Kun Wang, Guofeng Cai, Chuan He, Lingjian Yang

Pages: 4388-4400 Published online on: 21 March 2019

Preliminary investigation of the effects of an FCF inhibitor interference with Septin in the early stage embryos in mice

Shao‑Qin Ge, Yin‑Ling Wu, Jin‑Liang Zhu, Yuan Tian, Shu‑Song Wang, Zhang‑Quan Gao

Pages: 4401-4406 Published online on: 21 March 2019

A novel NHS mutation in a Chinese family with Nance‑Horan Syndrome

Meirong Wei, Anhui Qi, Haiming Mo, Kailin Wu, Xu Ma, Binbin Wang

Pages: 4419-4424 Published online on: 29 March 2019

MicroRNA‑302a upregulation mediates chemo‑resistance in prostate cancer cells

Yuqi Wu, Li Hu, Zizhen Qin, Xiangwei Wang

Pages: 4433-4440 Published online on: 28 March 2019

Serum‑derived hepatitis C virus can infect human glioblastoma cell line SF268 and activate the PI3K‑Akt pathway

Guosheng Yuan, Liang Rong, Junwei Liu, Zhenzhen Zhang, Chengguang Hu, Mingxiao Chen, Ling Ma, Yong‑Yuan Zhang, Yi‑Ping Li, Yuanping Zhou

Pages: 4441-4448 Published online on: 19 March 2019

MicroRNA‑494 inhibits apoptosis of murine vascular smooth muscle cells in vitro

Rongrong Cui, Senlin Ye, Jiayu Zhong, Lingjuan Liu, Shijun Li, Xiao Lin, Lingqing Yuan, Lu Yi

Pages: 4457-4467 Published online on: 26 March 2019

Long noncoding RNA NEAT1 sponges miR‑125a‑5p to suppress cardiomyocyte apoptosis via BCL2L12

Hong Yan, Huasheng Liang, Lie Liu, Dongli Chen, Qianhuan Zhang

Pages: 4468-4474 Published online on: 27 March 2019

Downregulation of microRNA‑183‑5p inhibits the proliferation and invasion of colorectal cancer cells by inactivating the reticulocalbin‑2/Wnt/β‑catenin signaling pathway

Gang Wang, Jingrong Zhou, Feng Lu, Lei Qiu, Liang Xu, Xiuwei Yang, Yongchang Miao

Pages: 4475-4483 Published online on: 19 March 2019

A Chinese pedigree with a novel mutation in GJB1 gene and a rare variation in DHTKD1 gene for diverse Charcot‑Marie‑Tooth diseases

Zhen‑Hua Zhao, Zhi‑Ting Chen, Rui‑Ling Zhou, Yin‑Zhou Wang

Pages: 4484-4490 Published online on: 19 March 2019

Renal dysfunction in a mouse model of GDM is prevented by metformin through MAPKs

Zhengfei Liu, Xinyang Yu, Chao Tong, Hongbo Qi

Pages: 4491-4499 Published online on: 19 March 2019

Circular RNA expression alterations in colon tissues of Crohn's disease patients

Yu Qi Qiao, Chen Wen Cai, Jun Shen, Qing Zheng, Zhi Hua Ran

Pages: 4500-4506 Published online on: 21 March 2019

Protective effects of propofol on experimental neonatal acute lung injury

Xiongwu Yu, Chuanfeng Li

Pages: 4507-4513 Published online on: 01 April 2019

HPT axis‑independent TSHβ splice variant regulates the synthesis of thyroid hormone in mice

Chunrong Liu, Jun Miao, Xiaorong Liu, Zhankao Zhao, Tianlei Kou, Jing Liu, Ruimin Wang, Lanying Li, Qian Dong

Pages: 4514-4522 Published online on: 22 March 2019
Journal Cover

May 2019
Volume 19 Issue 5

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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