Journal Articles

Open Access

Pain polymorphisms and opioids: An evidence based review

Cláudia Margarida Pereira Vieira, Rosa Maria Fragoso, Deolinda Pereira, Rui Medeiros

Pages: 1423-1434 Published online on: 24 December 2018
Open Access

Association of Epstein‑Barr virus infection with allogeneic hematopoietic stem cell transplantation in patients in Portugal

Joana Marinho‑Dias, Inês Baldaque, Carlos Pinho‑Vaz, Luís Leite, Rosa Branca, Fernando Campilho, António Campos, Rui Medeiros, Hugo Sousa

Pages: 1435-1442 Published online on: 24 December 2018
Open Access

Low‑dose lipopolysaccharide inhibits neuronal apoptosis induced by cerebral ischemia/reperfusion injury via the PI3K/Akt/FoxO1 signaling pathway in rats

Fan He, Nannan Zhang, Yan Lv, Wenhao Sun, Huisheng Chen

Pages: 1443-1452 Published online on: 07 January 2019
Open Access

Ticagrelor suppresses oxidized low‑density lipoprotein‑induced endothelial cell apoptosis and alleviates atherosclerosis in ApoE‑/‑ mice via downregulation of PCSK9

Xiaodong Xia, Jiao Li, Xue Liang, Shengjie Zhang, Tong Liu, Jinying Liu, Muhammad Arif, Guangping Li

Pages: 1453-1462 Published online on: 20 December 2018
Open Access

MiR‑495 suppresses cell proliferation by directly targeting HMGA2 in lung cancer

Jiangtao Sun, Yanping Qiao, Tao Song, Haiwen Wang

Pages: 1463-1470 Published online on: 17 December 2018
Open Access

Optimized protocols for γδ T cell expansion and lentiviral transduction

Rui‑Ning Wang, Qian Wen, Wen‑Ting He, Jia‑Hui Yang, Chao‑Ying Zhou, Wen‑Jing Xiong, Li Ma

Pages: 1471-1480 Published online on: 08 January 2019
Open Access

miR‑675 promotes colorectal cancer cell growth dependent on tumor suppressor DMTF1

Xueliang Yang, Yang Lou, Minghua Wang, Chunlei Liu, Yanbo Liu, Weili Huang

Pages: 1481-1490 Published online on: 20 December 2018
Open Access

MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang

Pages: 1491-1500 Published online on: 18 December 2018
Open Access

Epithelial‑mesenchymal transition induced by bone morphogenetic protein 9 hinders cisplatin efficacy in ovarian cancer cells

Ying Wang, Bin Yang, Jinping Zhao, Xiaohui Yu, Xing Liu, Long Zhang, Yunjing Zhang, Xiaoli Li, Zhenhua Zhai

Pages: 1501-1508 Published online on: 03 January 2019
Open Access

Epigallocatechin‑3‑gallate modulates long non‑coding RNA and mRNA expression profiles in lung cancer cells

Dong‑Li Hu, Guo Wang, Jing Yu, Li‑Hua Zhang, Yuan‑Fei Huang, Dan Wang, Hong‑Hao Zhou

Pages: 1509-1520 Published online on: 03 January 2019
Open Access

Astrocytes enhance the tolerance of rat cortical neurons to glutamate excitotoxicity

Li‑Nan Zhang, Qi Wang, Xiao‑Hui Xian, Jie Qi, Li‑Zhe Liu, Wen‑Bin Li

Pages: 1521-1528 Published online on: 24 December 2018
Open Access

Systematic screening and identification of novel psoriasis‑specific genes from the transcriptome of psoriasis‑like keratinocytes

Zhen Wang, Huaping Zheng, Hong Zhou, Nongyu Huang, Xiaoqiong Wei, Xiao Liu, Xiu Teng, Zhonglan Hu, Jun Zhang, Xikun Zhou, Wei Li, Jiong Li

Pages: 1529-1542 Published online on: 20 December 2018
Open Access

MicroRNA‑219 overexpression serves a protective role during liver fibrosis by targeting tumor growth factor β receptor 2

Li Ma, Jian Ma, Hong‑Liang Ou

Pages: 1543-1550 Published online on: 21 December 2018
Open Access

Luteolin suppresses lipopolysaccharide‑induced cardiomyocyte hypertrophy and autophagy in vitro

Xing Li, Jian Liu, Jianfeng Wang, Donghua Zhang

Pages: 1551-1560 Published online on: 02 January 2019
Open Access

ATP synthase is required for male fertility and germ cell maturation in Drosophila testes

Jun Yu, Binghai Chen, Bo Zheng, Chen Qiao, Xia Chen, Yidan Yan, Xiaojin Luan, Bing Xie, Jiajia Liu, Cong Shen, Zeyu He, Xing Hu, Mingxi Liu, Hong Li, Qixiang Shao, Jie Fang

Pages: 1561-1570 Published online on: 08 January 2019
Open Access

Identification of differentially expressed genes in MG63 osteosarcoma cells with drug‑resistance by microarray analysis

Rui Chen, Li‑Hong Huang, Yi‑Yao Gao, Jian‑Zeng Yang, Yan Wang

Pages: 1571-1580 Published online on: 18 December 2018
Open Access

LncRNA BANCR participates in polycystic ovary syndrome by promoting cell apoptosis

Ruirui Yang, Jianmei Chen, Li Wang, Aijing Deng

Pages: 1581-1586 Published online on: 24 December 2018
Open Access

High‑level SETD1B gene expression is associated with unfavorable prognosis in hepatocellular carcinoma

Dong Chen, Tieling Li, Cheng Wang, Guanglin Lei, Ruilan Wang, Zhaohai Wang, Linxiang Yu, Jin Yan, Peirui Zhang, Xiliang Wang, Shaogeng Zhang, Penghui Yang

Pages: 1587-1594 Published online on: 08 January 2019
Open Access

Butyl stearate prolongs the drug release period of isoperidone‑loaded poly (lactic‑co‑glycolic acid) microspheres: In vitro and in vivo investigation

Fengying Sun, Changhui Yu, Ximing Liu, Dan Wang, Na Liu, Jiaxin Liu, Lesheng Teng, Youxin Li

Pages: 1595-1602 Published online on: 24 December 2018
Open Access

Astragaloside IV prevents high glucose‑induced cell apoptosis and inflammatory reactions through inhibition of the JNK pathway in human umbilical vein endothelial cells

Liangzhen You, Zhaohui Fang, Guoming Shen, Qin Wang, Ying He, She Ye, Liu Wang, Mengjie Hu, Yixuan Lin, Mengmeng Liu, Aijuan Jiang

Pages: 1603-1612 Published online on: 03 January 2019
Open Access

A thirteen‑gene set efficiently predicts the prognosis of glioblastoma

Huyin Yang, Luhao Jin, Xiaoyang Sun

Pages: 1613-1621 Published online on: 02 January 2019
Open Access

Combination leflunomide and methotrexate impedes the recovery of liver fibrosis, partly through inhibition of myeloid cell admittance

Mengxin Lin, Ruyi Guo, Zhijun Su, Shaopeng Ke, Dawu Zeng

Pages: 1622-1628 Published online on: 04 January 2019
Open Access

EVI‑1 acts as an oncogene and positively regulates calreticulin in breast cancer

Lei Wu, Tianyi Wang, Dongning He, Xiaoxi Li, Youhong Jiang

Pages: 1645-1653 Published online on: 24 December 2018
Open Access

Novel 1,4‑naphthoquinone derivatives induce reactive oxygen species‑mediated apoptosis in liver cancer cells

Yue Wang, Ying‑Hua Luo, Xian‑Ji Piao, Gui‑Nan Shen, Ling‑Qi Meng, Yi Zhang, Jia‑Ru Wang, Jin‑Qian Li, Hao Wang, Wan‑Ting Xu, Yang Liu, Yu Zhang, Tong Zhang, Shi‑Nong Wang, Hu‑Nan Sun, Ying‑Hao Han, Mei‑Hua Jin, Yan‑Qing Zang, Dong‑Jie Zhang, Cheng‑Hao Jin

Pages: 1654-1664 Published online on: 21 December 2018
Open Access

Insulin ameliorates pulmonary edema through the upregulation of epithelial sodium channel via the PI3K/SGK1 pathway in mice with lipopolysaccharide‑induced lung injury

Wang Deng, Chang‑Yi Li, Jin Tong, Jing He, Yan Zhao, Dao‑Xin Wang

Pages: 1665-1677 Published online on: 02 January 2019
Open Access

CCL18 enhances migration, invasion and EMT by binding CCR8 in bladder cancer cells

Xiaoqiang Liu, Xiangyun Xu, Wen Deng, Mingchuan Huang, Yanlong Wu, Zhengtao Zhou, Ke Zhu, Yibing Wang, Xinfu Cheng, Xiaochen Zhou, Luyao Chen, Yu Li, Gongxian Wang, Bin Fu

Pages: 1678-1686 Published online on: 24 December 2018
Open Access

Low‑frequency pulsed electromagnetic field promotes functional recovery, reduces inflammation and oxidative stress, and enhances HSP70 expression following spinal cord injury

Chunyan Wang, Yang Liu, Yao Wang, Zhijian Wei, Dongmei Suo, Guangzhi Ning, Qiuli Wu, Shiqing Feng, Chunxiao Wan

Pages: 1687-1693 Published online on: 04 January 2019
Open Access

Febuxostat inhibits TGF‑β1‑induced epithelial‑mesenchymal transition via downregulation of USAG‑1 expression in Madin‑Darby canine kidney cells in vitro

Linghong Lu, Jiajun Zhu, Yaqian Zhang, Yanxia Wang, Shu Zhang, Anzhou Xia

Pages: 1694-1704 Published online on: 02 January 2019
Open Access

‘Heart development and morphogenesis’ is a novel pathway for human ovarian granulosa cell differentiation during long‑term in vitro cultivation‑a microarray approach

Wiesława Kranc, Maciej Brązert, Piotr Celichowski, Artur Bryja, Mariusz J. Nawrocki, Katarzyna Ożegowska, Maurycy Jankowski, Michal Jeseta, Leszek Pawelczyk, Andrzej Bręborowicz, Dominik Rachoń, Mariusz T. Skowroński, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty

Pages: 1705-1715 Published online on: 08 January 2019
Open Access

Whole exome sequencing identifies hemizygous deletions in the UGT2B28 and USP17L2 genes in a three‑generation family with endometriosis

Hans M. Albertsen, Charoula Matalliotaki, Michail Matalliotakis, Maria I. Zervou, Ioannis Matalliotakis, Demetrios A. Spandidos, Rakesh Chettier, Kenneth Ward, George N. Goulielmos

Pages: 1716-1720 Published online on: 03 January 2019
Open Access

Intermittent fasting increases the expressions of SODs and catalase in granule and polymorphic cells and enhances neuroblast dendrite complexity and maturation in the adult gerbil dentate gyrus

Ji Hyeon Ahn, Bich Na Shin, Minah Song, Hyunjung Kim, Joon Ha Park, Tae‑Kyeong Lee, Cheol Woo Park, Young Eun Park, Jae‑Chul Lee, Jun‑Hwan Yong, Choong‑Hyun Lee, In Koo Hwang, Moo‑Ho Won, Yun Lyul Lee

Pages: 1721-1727 Published online on: 04 January 2019

Anti‑inflammatory effect of ciclamilast in an allergic model involving the expression of PDE4B

Xu‑Yang Zheng, Jun‑Chun Chen, Qiang‑Min Xie, Ji‑Qiang Chen, Hui‑Fang Tang

Pages: 1728-1738 Published online on: 02 January 2019

Function of Krüppel‑like factor 2 in the shear stress‑induced cell differentiation of endothelial progenitor cells to endothelial cells

Hai‑Rong Chu, Yu‑Cong Sun, Yu Gao, Xiu‑Mei Guan, Hong Yan, Xiao‑Dong Cui, Xiao‑Yun Zhang, Xin Li, Hong Li, Min Cheng

Pages: 1739-1746 Published online on: 03 January 2019

miR‑584‑5p regulates migration and invasion in non‑small cell lung cancer cell lines through regulation of MMP‑14

Tianmin Guo, Chenzhao Zheng, Zhigang Wang, Xifu Zheng

Pages: 1747-1752 Published online on: 03 January 2019

MicroRNA‑192 acts as a tumor suppressor in colon cancer and simvastatin activates miR‑192 to inhibit cancer cell growth

Xiao‑Fang Zheng, Kun‑Xiang Liu, Xin‑Mei Wang, Rui Zhang, Xin Li

Pages: 1753-1760 Published online on: 02 January 2019

Integrative analysis of shared genetic pathogenesis by obsessive‑compulsive and eating disorders

Cheng Xu, Hongbao Cao, Dongbai Liu

Pages: 1761-1766 Published online on: 17 December 2018

Galangin decreases p‑tau, Aβ42 and β‑secretase levels, and suppresses autophagy in okadaic acid‑induced PC12 cells via an Akt/GSK3β/mTOR signaling‑dependent mechanism

Liping Huang, Mingqin Lin, Xiaoqin Zhong, Hongyan Yang, Minzhen Deng

Pages: 1767-1774 Published online on: 04 January 2019

A novel dominant mutation in the SOX10 gene in a Chinese family with Waardenburg syndrome type II

Jing Ma, Zhen Zhang, Hong‑Chao Jiang, Hao Sun, Cheng Ming, Li‑Ping Zhao, Ying‑Qin Gao, Zheng‑Cai Li, Mei‑Hua Sun, Yang Xiao, Guo‑Li Wu, Tie‑Song Zhang, Biao Ruan

Pages: 1775-1780 Published online on: 03 January 2019

Dexamethasone protects against arsanilic acid‑induced rat vestibular dysfunction through the BDNF and JNK 1/2 signaling pathways

Yan Luo, Daogong Zhang, Yueling Chen, Zhongsheng Cao, Zhaomin Fan

Pages: 1781-1790 Published online on: 08 January 2019

Prenatal diagnosis of sex chromosome mosaicism with two marker chromosomes in three cell lines and a review of the literature

Jianli Zheng, Xiaoyu Yang, Haiyan Lu, Yongjuan Guan, Fangfang Yang, Mengjun Xu, Min Li, Xiuqing Ji, Yan Wang, Ping Hu, Yun Zhou

Pages: 1791-1796 Published online on: 24 December 2018

The mitochondrial transfer RNAAsp A7551G mutation may contribute to the clinical expression of deafness associated with the A1555G mutation in a pedigree with hearing impairment

Jing Zhang, Bo Lu, Wei‑Wei Xia, Bin Fang, Xiao‑Xia Ding, Guang‑Wei Hu

Pages: 1797-1802 Published online on: 24 December 2018

Aldosterone induces renal fibrosis by promoting HDAC1 expression, deacetylating H3K9 and inhibiting klotho transcription

Lingyun Lai, Ping Cheng, Minhua Yan, Yong Gu, Jun Xue

Pages: 1803-1808 Published online on: 20 December 2018

Standardized microwave extract of Sappan Lignum exerts anti‑inflammatory effects through inhibition of NF‑κB activation via regulation of heme oxygenase‑1 expression

Md Anisuzzaman Chowdhury, Moonbum Choi, Wonmin Ko, Hwan Lee, Sam Cheol Kim, Hyuncheol Oh, Eun‑Rhan Woo, Youn‑Chul Kim, Dong‑Sung Lee

Pages: 1809-1816 Published online on: 02 January 2019

Protective effects of metformin on lipopolysaccharide‑induced airway epithelial cell injury via NF‑κB signaling inhibition

Jiayang Sun, Niwen Huang, Wen Ma, Haiyan Zhou, Kefang Lai

Pages: 1817-1823 Published online on: 02 January 2019

The novel long non‑coding RNA PRNCR1‑2 is involved in breast cancer cell proliferation, migration, invasion and cell cycle progression

Danmei Pang, Qian Hu, Xiaoshan Lan, Yingxin Lin, Haibo Duan, Shuo Cao, Yaodong Lin, Litao Li, Feng Peng, Fengtao Pan

Pages: 1824-1832 Published online on: 24 December 2018

HBV infection suppresses the expression of inflammatory macrophage miR‑210

Feifei Li, Hongjun Bian, Wenwen Wang, Liping Ning, Miao Xu, Shuohuan Sun, Wanhua Ren, Chengyong Qin, Jianni Qi

Pages: 1833-1839 Published online on: 24 December 2018

Aryl hydrocarbon receptor activation modulates γδ intestinal intraepithelial lymphocytes and protects against ischemia/reperfusion injury in the murine small intestine

Zhicao Zhang, Aimin Pu, Min Yu, Weidong Xiao, Lihua Sun, Yujiao Cai, Hua Yang

Pages: 1840-1848 Published online on: 04 January 2019

miR‑34a derived from mesenchymal stem cells stimulates senescence in glioma cells by inducing DNA damage

Qun Li, Chengde Wang, Lin Cai, Jianglong Lu, Zhangzhang Zhu, Chunyong Wang, Zhipeng Su, Xianghe Lu

Pages: 1849-1857 Published online on: 24 December 2018

Tougu Xiaotong capsule exerts a therapeutic effect on knee osteoarthritis by regulating subchondral bone remodeling

Guangwen Wu, Jiahui Zhang, Wenlie Chen, Sainan Chen, Yunmei Huang, Ruhui Lin, Meiya Huang, Zuanfang Li, Liangpu Zheng, Xihai Li

Pages: 1858-1866 Published online on: 20 December 2018

Comparison of remote ischemic preconditioning and intermittent hypoxia training in fracture healing

Junjie Qiao, Meng Zhou, Zheng Li, Jie Ren, Guanghan Gao, Guanglei Cao, Huiliang Shen, Shibao Lu

Pages: 1867-1874 Published online on: 24 December 2018

microRNA‑577 inhibits cell proliferation and invasion in non‑small cell lung cancer by directly targeting homeobox A1

Lan Men, Dandan Nie, Haiying Nie

Pages: 1875-1882 Published online on: 02 January 2019

MicroRNA‑758 inhibits tumorous behavior in tongue squamous cell carcinoma by directly targeting metadherin

Yulan Zhang, Fuquan Zhao

Pages: 1883-1890 Published online on: 02 January 2019

MicroRNA‑744 suppresses cell proliferation and invasion of papillary thyroid cancer by directly targeting NOB1

Haixia Liu, Jing Guo, Hongyan Chai, Xiangfeng Meng

Pages: 1903-1910 Published online on: 04 January 2019

Radix Sophorae Flavescentis inhibits proliferation and induces apoptosis of AGS human gastric cancer cells

Ji Sun Kim, Seung Jae Shin, Jung Nam Kim, Min Ji Kwon, Eun Yeong Lim, Yun Tai Kim, Hyungwoo Kim, Byung Joo Kim

Pages: 1911-1918 Published online on: 18 December 2018

Effects of various doses of atorvastatin on vascular endothelial cell apoptosis and autophagy in vitro

Wen‑Bo Zhao, Hui Fu, Fen Chang, Jing Liu, Jinlan Wang, Fang Li, Jing Zhao

Pages: 1919-1925 Published online on: 08 January 2019

MicroRNA‑18b acts as an oncogene in gastric cancer by directly targeting Kruppel‑like factor 6

Dongming Luo, Junqiang Chen, Shifeng Huang, Junyi Xu, Xuemin Song, Pengcheng Yu

Pages: 1926-1934 Published online on: 08 January 2019

NLRP3 inflammasome as the potential target mechanism and therapy in recurrent spontaneous abortions

Mudan Lu, Fengying Ma, Jianping Xiao, Lan Yang, Na Li, Daozhen Chen

Pages: 1935-1941 Published online on: 08 January 2019

Long non‑coding RNA DLX6‑AS1 is associated with malignant progression and promotes proliferation and invasion in esophageal squamous cell carcinoma

Mingchen Wang, Yuan Li, Yixin Yang, Xiaosa Liu, Mingxi Zang, Yuebai Li, Kunpeng Yang, Wanguang Yang, Shanfeng Zhang

Pages: 1942-1950 Published online on: 21 December 2018

miR‑625‑5p suppresses inflammatory responses by targeting AKT2 in human bronchial epithelial cells

Fen-Hong Qian, Xia Deng, Qiong-Xin Zhuang, Bin Wei, Dan-Dan Zheng

Pages: 1951-1957 Published online on: 03 January 2019

Kaempferol inhibits multiple pathways involved in the secretion of inflammatory mediators from LPS‑induced rat intestinal microvascular endothelial cells

Yifei Bian, Ping Liu, Jia Zhong, Yusheng Hu, Yingsai Fan, Shen Zhuang, Zhongjie Liu

Pages: 1958-1964 Published online on: 18 December 2018

Inhibition of microRNA‑492 attenuates cell proliferation and invasion in retinoblastoma via directly targeting LATS2

Zhiqun Sun, Aimei Zhang, Liming Zhang

Pages: 1965-1971 Published online on: 20 December 2018

Bergapten induces G1 arrest of non‑small cell lung cancer cells, associated with the p53‑mediated cascade

Shyh‑Ren Chiang, Chun‑Shiang Lin, Hui‑Han Lin, Pei‑Chen Shieh, Shao‑Hsuan Kao

Pages: 1972-1978 Published online on: 02 January 2019
Open Access

[Corrigendum] Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-κB-dependent matrix metalloproteinase-9 expression

Zanjing Zhai, Xinhua Qu, Haowei Li, Zhengxiao Ouyang, Wei Yan, Guangwang Liu, Xuqiang Liu, Qiming Fan, Tingting Tang, Kerong Dai, An Qin

Pages: 1979-1979 Published online on: 08 January 2019

Investigational drugs in HIV: Pros and cons of entry and fusion inhibitors (Review)

Emmanuele Venanzi Rullo, Manuela Ceccarelli, Fabrizio Condorelli, Alessio Facciolà, Giuseppa Visalli, Francesco D'Aleo, Ivana Paolucci, Bruno Cacopardo, Marilia Rita Pinzone, Michele Di Rosa, Giuseppe Nunnari, Giovanni F. Pellicanò

Pages: 1987-1995 Published online on: 10 January 2019
Open Access

Postnatal changes in constitutive cyclooxygenase‑2 expression in the mice hippocampus and its function in synaptic plasticity

Hyo Young Jung, Dae Young Yoo, Sung Min Nam, Jong Whi Kim, Woosuk Kim, Hyun Jung Kwon, Kwon Young Lee, Jung Hoon Choi, Dae Won Kim, Yeo Sung Yoon, Je Kyung Seong, In Koo Hwang

Pages: 1996-2004 Published online on: 15 January 2019
Open Access

Escherichia coli promotes DSS‑induced murine colitis recovery through activation of the TLR4/NF‑κB signaling pathway

Jiabao Lu, Boye Dong, Ailan Chen, Feng He, Baifu Peng, Zixin Wu, Jie Cao, Wanglin Li

Pages: 2021-2028 Published online on: 11 January 2019
Open Access

Identification of differentially expressed genes and enriched pathways in lung cancer using bioinformatics analysis

Tingting Long, Zijing Liu, Xing Zhou, Shuang Yu, Hui Tian, Yixi Bao

Pages: 2029-2040 Published online on: 18 January 2019
Open Access

Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumor

Xiaofu Wang, Pan Song, Chuiguo Huang, Naijun Yuan, Xinghua Zhao, Changbao Xu

Pages: 2041-2050 Published online on: 21 January 2019

LncRNA‑NEF is involved the regulation of gastric carcinoma cell proliferation by targeting RUNX1

Xue Wang, Xue Jiang, Li Zhou, Zhuo Wang, He Huang, Mengqiao Wang

Pages: 2051-2056 Published online on: 16 January 2019
Open Access

Curculigoside exerts significant anti‑arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF‑κB signaling pathway

Shirui Tan, Jian Xu, Aiyun Lai, Ruomei Cui, Ru Bai, Shu Li, Wei Liang, Guofang Zhang, Shaoquan Jiang, Shuang Liu, Mai Zheng, Wei Wang

Pages: 2057-2064 Published online on: 14 January 2019
Open Access

Identification of key genes and pathways involved in microsatellite instability in colorectal cancer

Chaoran Yu, Hiju Hong, Sen Zhang, Yaping Zong, Junjun Ma, Aiguo Lu, Jing Sun, Minhua Zheng

Pages: 2065-2076 Published online on: 11 January 2019
Open Access

Expression of flTF and asTF splice variants in various cell strains and tissues

Lili Pan, Yang Yu, Miaomei Yu, Shuang Yao, Qinfeng Mu, Guanghua Luo, Ning Xu

Pages: 2077-2086 Published online on: 10 January 2019
Open Access

Anti‑inflammatory effects of Dendropanax morbifera in lipopolysaccharide‑stimulated RAW264.7 macrophages and in an animal model of atopic dermatitis

Gang‑Sik Choo, Dong‑Pyo Lim, Sae‑Man Kim, Eun‑Seon Yoo, Sung‑Hyun Kim, Chang‑Hyun Kim, Joong‑Seok Woo, Hyeong‑Jin Kim, Ji‑Youn Jung

Pages: 2087-2096 Published online on: 22 January 2019
Open Access

Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells

Aldo F. Clemente‑Soto, Enrique Salas‑Vidal, Cesar Milan‑Pacheco, Jessica Nayelli Sánchez‑Carranza, Oscar Peralta‑Zaragoza, Leticia González‑Maya

Pages: 2097-2106 Published online on: 11 January 2019
Open Access

Mechanical force promotes the proliferation and extracellular matrix synthesis of human gingival fibroblasts cultured on 3D PLGA scaffolds via TGF‑β expression

Lan Nan, Yi Zheng, Ni Liao, Songze Li, Yao Wang, Zhixing Chen, Liying Wei, Shuang Zhao, Shuixue Mo

Pages: 2107-2114 Published online on: 21 January 2019
Open Access

HepaCAM inhibits cell proliferation and invasion in prostate cancer by suppressing nuclear translocation of the androgen receptor via its cytoplasmic domain

Qingfu Deng, Li Luo, Zhen Quan, Nanjing Liu, Zhongbo Du, Wei Sun, Chunli Luo, Xiaohou Wu

Pages: 2115-2124 Published online on: 10 January 2019
Open Access

Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma

Huan Zhou, Shun Tan, Hong Li, Xiangtao Lin

Pages: 2125-2136 Published online on: 22 January 2019
Open Access

Effects of UPF1 expression on EMT process by targeting E‑cadherin, N‑cadherin, Vimentin and Twist in a hepatocellular carcinoma cell line

Yawei Li, Tiantian Zhang, Shukui Qin, Rui Wang, Yumei Li, Zhengguang Zhou, Yufo Chen, Qiong Wu, Fang Su

Pages: 2137-2143 Published online on: 10 January 2019
Open Access

Upregulation of miR‑33b promotes endometriosis via inhibition of Wnt/β‑catenin signaling and ZEB1 expression

Haiyan Zhang, Guang Li, Xiugui Sheng, Shiqian Zhang

Pages: 2144-2152 Published online on: 17 January 2019
Open Access

Effects of nuclear respiratory factor‑1 on apoptosis and mitochondrial dysfunction induced by cobalt chloride in H9C2 cells

Nan Niu, Zihua Li, Mingxing Zhu, Hongli Sun, Jihui Yang, Shimei Xu, Wei Zhao, Rong Song

Pages: 2153-2163 Published online on: 10 January 2019
Open Access

Long noncoding RNA GAS5 promotes apoptosis in primary nucleus pulposus cells derived from the human intervertebral disc via Bcl‑2 downregulation and caspase‑3 upregulation

Yifeng Wang, Qingxin Song, Xuan Huang, Zhi Chen, Fan Zhang, Kun Wang, Guofeng Huang, Hongxing Shen

Pages: 2164-2172 Published online on: 22 January 2019
Open Access

PDCD2 sensitizes HepG2 cells to sorafenib by suppressing epithelial‑mesenchymal transition

Hongyu Liu, Min Wang, Na Liang, Lianyue Guan

Pages: 2173-2179 Published online on: 15 January 2019
Open Access

NLRP3 inflammasome inactivation driven by miR‑223‑3p reduces tumor growth and increases anticancer immunity in breast cancer

Liping Zhang, Hongzhi Li, Yuwei Zang, Feng Wang

Pages: 2180-2188 Published online on: 23 January 2019
Open Access

Effects of storage culture media, temperature and duration on human adipose‑derived stem cell viability for clinical use

Yin‑Di Wu, Meng Li, Xuan Liao, Sheng‑Hong Li, Jian‑Xin Yan, Lei Fan, Wen‑Li She, Jian‑Xin Song, Hong‑Wei Liu

Pages: 2189-2201 Published online on: 10 January 2019
Open Access

Kinesin family member 20B regulates tongue cancer progression by promoting cell proliferation

Zhang‑Yi Li, Zhi‑Xing Wang, Chang‑Chun Li

Pages: 2202-2210 Published online on: 11 January 2019
Open Access

Sodium azide induces mitochondria‑mediated apoptosis in PC12 cells through Pgc‑1α‑associated signaling pathway

Yuanyi Zuo, Jun Hu, Xuehua Xu, Xiangting Gao, Yun Wang, Shaohua Zhu

Pages: 2211-2219 Published online on: 14 January 2019
Open Access

Genetic polymorphisms of melatonin receptors 1A and 1B may result in disordered lipid metabolism in obese patients with polycystic ovary syndrome

Xiu‑Hua Xu, Lian‑Cui Kou, Hai‑Mei Wang, Chun‑Mei Bo, Xiao‑Cui Song

Pages: 2220-2230 Published online on: 17 January 2019
Open Access

MicroRNA‑31 promotes chondrocyte proliferation by targeting C‑X‑C motif chemokine ligand 12

Yankun Dai, Shanglun Liu, Xueguan Xie, Mingsheng Ding, Quan Zhou, Xiaoqing Zhou

Pages: 2231-2237 Published online on: 15 January 2019
Open Access

Bioinformatics analysis of sex differences in arrhythmogenic right ventricular cardiomyopathy

Lai‑Te Chen, Chen‑Yang Jiang

Pages: 2238-2244 Published online on: 17 January 2019
Open Access

Piperazine ferulate ameliorates the development of diabetic nephropathy by regulating endothelial nitric oxide synthase

Yong‑Yu Yang, Ling‑Xing Shi, Jian‑He Li, Liang‑Yuan Yao, Da‑Xiong Xiang

Pages: 2245-2253 Published online on: 17 January 2019
Open Access

Scutellaria barbata polysaccharides inhibit tumor growth and affect the serum proteomic profiling of hepatoma H22‑bearing mice

Li Li, Xiaoyi Xu, Leilei Wu, Haicheng Zhu, Zhipeng He, Bo Zhang, Yanjun Chi, Gaochen Song

Pages: 2254-2262 Published online on: 15 January 2019

Knockdown of ACTA2‑AS1 promotes liver cancer cell proliferation, migration and invasion

Ru‑Jian Zhou, Hui‑Zeng Lv

Pages: 2263-2270 Published online on: 15 January 2019

The estrogen‑like protective effect of Lycium barbarum polysaccharides in reducing oxidative stress on myocardial cells from ovariectomized rats

Ning Yu, Nan Song, Chun Ying Liu, Guan Lin Yang

Pages: 2271-2278 Published online on: 18 January 2019

Sodium houttuyfonate inhibits LPS‑induced mastitis in mice via the NF‑κB signalling pathway

Pei Liu, Chao Yang, Sihui Lin, Gan Zhao, Tao Zhang, Shuai Guo, Kangfeng Jiang, Haichong Wu, Changwei Qiu, Mengyao Guo, Ganzhen Deng

Pages: 2279-2286 Published online on: 10 January 2019

Cx32 mediates cisplatin resistance in human ovarian cancer cells by affecting drug efflux transporter expression and activating the EGFR‑Akt pathway

Yu Zhang, Liang Tao, Li‑Xia Fan, Kun Huang, Hui‑Min Luo, Hui Ge, Xiyan Wang, Qin Wang

Pages: 2287-2296 Published online on: 17 January 2019

ZEB1 promotes tumorigenesis and metastasis in hepatocellular carcinoma by regulating the expression of vimentin

Yue Qin, Jingxi Yu, Ming Zhang, Faxiang Qin, Xiong Lan

Pages: 2297-2306 Published online on: 15 January 2019

β‑elemene inhibits oxygen‑induced retinal neovascularization via promoting miR‑27a and reducing VEGF expression

Weilai Zhang, Lei Chen, Jin Geng, Limin Liu, Li Xu

Pages: 2307-2316 Published online on: 15 January 2019

IL‑6 prevents CXCL8‑induced stimulation of EpCAM expression in ovarian cancer cells

Lucyna Kapka‑Skrzypczak, Sylwia Popek, Krzysztof Sawicki, Bartłomiej Drop, Magdalena Czajka, Barbara Jodłowska‑Jędrych, Magdalena Matysiak‑Kucharek, Dominika Furman‑Toczek, Martyna Zagórska‑Dziok, Marcin Kruszewski

Pages: 2317-2322 Published online on: 23 January 2019

Expression and functional analysis of Brucella outer membrane protein 25 in recombinant goat pox virus

Zhihua Sun, Laizhen Liu, Hui Zhang, Youwen Li, Feng Wei, Zhiqiang Li, Pengyan Wang, Qiang Fu, Yan Ren, Yu Zhang, Zhiru Guo, Chuangfu Chen

Pages: 2323-2329 Published online on: 16 January 2019

Values of applying white blood cell counts in the prognostic evaluation of resectable colorectal cancer

Jing Wu, Xin‑Xin Ge, Wenyu Zhu, Qiaoming Zhi, Meng‑Dan Xu, Weiming Duan, Kai Chen, Fei‑Ran Gong, Min Tao, Liu‑Mei Shou, Meng‑Yao Wu, Wen‑Jie Wang

Pages: 2330-2340 Published online on: 10 January 2019

Estradiol induces cell proliferation in MCF‑7 mammospheres through HER2/COX‑2

Chin‑Hu Wu, Hui‑Yu Chuang, Chiu‑Lin Wang, Chia‑Yi Hsu, Cheng‑Yu Long, Tsung‑Hua Hsieh, Eing‑Mei Tsai

Pages: 2341-2349 Published online on: 18 January 2019

Global pathway view analysis of microRNA clusters in myasthenia gravis

Chunrui Bo, Jianjian Wang, Huixue Zhang, Yuze Cao, Xiaoyu Lu, Tianfeng Wang, Yu Wang, Shuang Li, Xiaotong Kong, Xuesong Sun, Zhaojun Liu, Shangwei Ning, Lihua Wang

Pages: 2350-2360 Published online on: 10 January 2019

miRNA‑135a regulates Hut78 cell proliferation via the GATA‑3/TOX signaling pathway

Hong Wei, Ruifeng Liu, Xvli Guo, Yin Zhou, Bo Sun, Jialin Wang

Pages: 2361-2367 Published online on: 22 January 2019

Screening and preliminary validation of T lymphocyte immunoregulation‑associated long non‑coding RNAs in diabetic foot ulcers

Shujuan Xu, Xiaoyu Weng, Ya Wang, Dalun Lv, Meihong Zeng, Fen Zhao, Yu Sun

Pages: 2368-2376 Published online on: 17 January 2019

Expression and effects of leukemia inhibitory factor on nucleus pulposus degeneration

Qiang Xiao, Ji‑Huan Zeng, Hao Zhou, Quan‑He Qiu, Bo Ke, Liang Deng, Zhen‑Ming Hu, Jeffrey Roh, Min Dai

Pages: 2377-2385 Published online on: 17 January 2019

Altered expression of genes involved in brain energy metabolism as adaptive responses in rats exposed to chronic variable stress; changes in cortical level of glucogenic and neuroactive amino acids

Mariola Herbet, Dorota Natorska‑Chomicka, Agnieszka Korga, Marta Ostrowska, Magdalena Izdebska, Monika Gawrońska‑Grzywacz, Iwona Piątkowska‑Chmiel, Kamil Pawłowski, Brygida Ślaska, Ewa Poleszak, Jarosław Dudka

Pages: 2386-2396 Published online on: 15 January 2019

Ulinastatin inhibits apoptosis induced by serum deprivation in mesenchymal stem cells

Linhui Shi, Longqiang Ye, Panpan Liu, Danqin Liu, Gongjie Ye, Jiahong Chen, Zhouzhou Dong

Pages: 2397-2406 Published online on: 11 January 2019

miR‑671‑3p is downregulated in non‑small cell lung cancer and inhibits cancer progression by directly targeting CCND2

Yuanshan Yao, Yinjie Zhou, Xiaojun Fu

Pages: 2407-2412 Published online on: 15 January 2019

Expression of S100A8 is induced by interleukin‑1α in TR146 epithelial cells through a mechanism involving CCAAT/enhancer binding protein β

Mingqun Qin, Yantao Zou, Kanghua Zhong, Yong Guo, Xianqiong Zou

Pages: 2413-2420 Published online on: 15 January 2019

Participation of the AngII/TRPC6/NFAT axis in the pathogenesis of podocyte injury in rats with type 2 diabetes

Ruixia Ma, Yan Xu, Hanyan Zhou, Di Zhang, Dandan Yao, Limin Song, Yuan Liu

Pages: 2421-2430 Published online on: 17 January 2019

MicroRNA‑601 serves as a potential tumor suppressor in hepatocellular carcinoma by directly targeting PIK3R3

Yanan Song, Saifei He, Juhua Zhuang, Guoyu Wang, Jing Ni, Suiliang Zhang, Ying Ye, Wei Xia

Pages: 2431-2439 Published online on: 15 January 2019

β‑ecdysterone protects against apoptosis by promoting autophagy in nucleus pulposus cells and ameliorates disc degeneration

Feng Wen, Jun Yu, Cheng‑Jian He, Zhi‑Wen Zhang, Ao‑Fei Yang

Pages: 2440-2448 Published online on: 15 January 2019

Endothelial progenitor cell impairment mediated vasodilation dysfunction via diminishing nitric oxide production in postmenopausal females

Wan‑Zhou Wu, Da‑Jun Hu, Zhen‑Yu Wang, Long‑Sheng Liao, Chuan‑Chang Li

Pages: 2449-2457 Published online on: 23 January 2019
Open Access

[Corrigendum] Genome‑wide DNA methylation analysis of uterosacral ligaments in women with pelvic organ prolapse

Lifang Zhang, Ping Zheng, Aihong Duan, Yan Hao, Chang Lu, Dan Lu

Pages: 2458-2458 Published online on: 11 January 2019
Journal Cover

March 2019
Volume 19 Issue 3

Print ISSN: 1791-2997
Online ISSN: 1791-3004

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