Journal Articles

Open Access

IMP3 overexpression occurs in various important cancer types and is linked to aggressive tumor features: A tissue microarray study on 8,877 human cancers and normal tissues

Christoph Burdelski, Nilofar Jakani-Karimi, Frank Jacobsen, Christina Möller-Koop, Sarah Minner, Ronald Simon, Guido Sauter, Stefan Steurer, Till S. Clauditz, Waldemar Wilczak

Pages: 3-12 Published online on: 02 November 2017
Open Access

FSTL1 suppresses tumor cell proliferation, invasion and survival in non-small cell lung cancer

Xiaolei Ni, Xiaoming Cao, Yongquan Wu, Jian Wu

Pages: 13-20 Published online on: 31 October 2017
Open Access

CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway

Huijie Zhuang, Gang Cao, Changhua Kou, Tao Liu

Pages: 21-30 Published online on: 02 November 2017
Open Access

Influence of the Twist gene on the invasion and metastasis of colon cancer

Duowei Wang, Bikash Rai, Feng Qi, Tong Liu, Jinmiao Wang, Xiaodong Wang, Bozhao Ma

Pages: 31-44 Published online on: 06 November 2017
Open Access

PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells

Weidong Liu, Xuxu Liu, Lei Wang, Bin Zhu, Chang Zhang, Wei Jia, Hecheng Zhu, Xingdong Liu, Meizuo Zhong, Dan Xie, Yanyu Liu, Shasha Li, Jia Shi, Jianxing Lin, Xiaomeng Xia, Xingjun Jiang, Caiping Ren

Pages: 45-52 Published online on: 06 November 2017
Open Access

Placenta-specific protein 1 promotes cell proliferation and invasion in non-small cell lung cancer

Li Yang, Tian-Qi Zha, Xiang He, Liang Chen, Quan Zhu, Wei-Bing Wu, Feng-Qi Nie, Qian Wang, Chong-Shuang Zang, Mei-Ling Zhang, Jing He, Wei Li, Wen Jiang, Kai-Hua Lu

Pages: 53-60 Published online on: 09 November 2017
Open Access

miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2

Baoping Lang, Song Zhao

Pages: 71-80 Published online on: 01 November 2017
Open Access

Downregulation of miR‑19a‑3p promotes invasion, migration and bone metastasis via activating TGF‑β signaling in prostate cancer

Qingde Wa, Li Li, Hongcheng Lin, Xinsheng Peng, Dong Ren, Yan Huang, Peiheng He, Shuai Huang

Pages: 81-90 Published online on: 13 November 2017
Open Access

Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma

Atsushi Kurata, Masatoshi Yamada, Shin-Ichiro Ohno, Shigeru Inoue, Hirotsugu Hashimoto, Koji Fujita, Masakatsu Takanashi, Masahiko Kuroda

Pages: 91-100 Published online on: 10 November 2017
Open Access

HMGA2 facilitates epithelial-mesenchymal transition in renal cell carcinoma by regulating the TGF-β/Smad2 signaling pathway

Bo Kou, Wei Liu, Xiaoshuang Tang, Qingshan Kou

Pages: 101-108 Published online on: 10 November 2017
Open Access

Significant inhibition of infantile hemangioma growth by sustained delivery of urea from liposomes-in-microspheres

Xiaoshuang Zhu, Xiaonan Guo, Dakan Liu, Yubin Gong, Jin Sun, Changxian Dong

Pages: 109-118 Published online on: 20 November 2017
Open Access

EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway

Rui Huang, Huimin Liu, Yiran Chen, Yanjie He, Qian Kang, Sanfang Tu, Yingzhi He, Xuan Zhou, Lei Wang, Jilong Yang, Anqin Wu, Yuhua Li

Pages: 119-128 Published online on: 20 November 2017
Open Access

P2Y2 receptor promotes the migration and invasion of breast cancer cells via EMT-related genes Snail and E-cadherin

Ying Qiu, Yan Liu, Wei-Hua Li, Hong-Quan Zhang, Xin-Xia Tian, Wei-Gang Fang

Pages: 138-150 Published online on: 07 November 2017
Open Access

Immunogenic tumor cell death induced by chemotherapy in patients with breast cancer and esophageal squamous cell carcinoma

Keita Aoto, Kousaku Mimura, Hirokazu Okayama, Motonobu Saito, Shun Chida, Masaru Noda, Takahiro Nakajima, Katsuharu Saito, Noriko Abe, Shinji Ohki, Tohru Ohtake, Seiichi Takenoshita, Koji Kono

Pages: 151-159 Published online on: 14 November 2017
Open Access

Characterization of etoposide- and cisplatin-chemoresistant retinoblastoma cell lines

Maike Busch, David Papior, Harald Stephan, Nicole Dünker

Pages: 160-172 Published online on: 16 November 2017

Downregulation of microRNA-1274a induces cell apoptosis through regulation of BMPR1B in clear cell renal cell carcinoma

Hirofumi Yoshino, Tomokazu Yonezawa, Masaya Yonemori, Kazutaka Miyamoto, Takashi Sakaguchi, Satoru Sugita, Youichi Osako, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida

Pages: 173-181 Published online on: 15 November 2017

Effects of leptin on leptin receptor isoform expression and proliferative activity in human normal prostate and prostate cancer cell lines

Marta Szyszka, Marianna Tyczewska, Paulina Milecka, Karol Jopek, Piotr Celichowski, Ludwik K. Malendowicz, Marcin Rucinski

Pages: 182-192 Published online on: 01 November 2017

A novel mechanism of neovascularization in peritoneal dissemination via cancer-associated mesothelial cells affected by TGF-β derived from ovarian cancer

Kayo Fujikake, Hiroaki Kajiyama, Masato Yoshihara, Kimihiro Nishino, Nobuhisa Yoshikawa, Fumi Utsumi, Shiro Suzuki, Kaoru Niimi, Jun Sakata, Hiroko Mitsui, Kiyosumi Shibata, Takeshi Senga, Fumitaka Kikkawa

Pages: 193-200 Published online on: 20 November 2017

Influence of miR-7a and miR-24-3p on the SOX18 transcript in lung adenocarcinoma

Mateusz Olbromski, Adam Rzechonek, Jedrzej Grzegrzolka, Natalia Glatzel-Plucinska, Angelika Chachaj, Bozena Werynska, Marzenna Podhorska-Okolow, Piotr Dziegiel

Pages: 201-208 Published online on: 06 November 2017

Role of c-Met in the progression of human oral squamous cell carcinoma and its potential as a therapeutic target

Zujun Sun, Qi Liu, Dongxia Ye, Kaichuang Ye, Zhenhua Yang, Dong Li

Pages: 209-216 Published online on: 02 November 2017

The long non-coding RNA ENST00000547547 reduces 5-fluorouracil resistance of colorectal cancer cells via competitive binding to microRNA-31

Jian Li, Xiaorong Li, Chaoqun Cen, Xiaohui Ai, Changwei Lin, Gui Hu

Pages: 217-226 Published online on: 07 November 2017

Cepharanthine exhibits a potent anticancer activity in p53-mutated colorectal cancer cells through upregulation of p21Waf1/Cip1

Arkornnut Rattanawong, Vilawan Payon, Wacharee Limpanasittikul, Chatikorn Boonkrai, Apiwat Mutirangura, Piyanuch Wonganan

Pages: 227-238 Published online on: 09 November 2017

ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo

Soyeon Kim, Kaipeng Jing, Soyeon Shin, Soyeon Jeong, Seung-Hyeon Han, Heyrim Oh, Yoon-Seon Yoo, Jeongsu Han, Young-Joo Jeon, Jun-Young Heo, Gi-Ryang Kweon, Seung-Kiel Park, Jong-Il Park, Tong Wu, Kyu Lim

Pages: 239-246 Published online on: 16 November 2017

miR-16 mimics inhibit TGF-β1-induced epithelial-to-mesenchymal transition via activation of autophagy in non-small cell lung carcinoma cells

Hui Wang, Ying Zhang, Qian Wu, Yong-Bin Wang, Wei Wang

Pages: 247-254 Published online on: 09 November 2017

MicroRNA-615-5p targets insulin-like growth factor 2 and exerts tumor-suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou

Pages: 255-263 Published online on: 06 November 2017

Synergistic effects of the combination of 5-Aza‑CdR and suberoylanilide hydroxamic acid on the anticancer property of pancreatic cancer

Ting Han, Meng Zhuo, Hai Hu, Feng Jiao, Li-Wei Wang

Pages: 264-270 Published online on: 31 October 2017

Combined 18F-FDG PET/CT imaging and a gastric orthotopic xenograft model in nude mice are used to evaluate the efficacy of glycolysis-targeted therapy

Ting-An Wang, Shu-Lin Xian, Xing-Yu Guo, Xiao-Dong Zhang, Yun-Fei Lu

Pages: 271-279 Published online on: 31 October 2017

Effect of xanthohumol on Th1/Th2 balance in a breast cancer mouse model

Wenchao Zhang, Yanlong Pan, Panhong Gou, Cheng Zhou, Lianqing Ma, Qiming Liu, Yuping Du, Jinbo Yang, Qin Wang

Pages: 280-288 Published online on: 13 November 2017

Downregulation of microRNA-95-3p suppresses cell growth of osteosarcoma via CDKN1A/p21 expression

Xin Zhao, Yukai Yang, Jianting Xu, Yang Luo, Ying Xin, Yanbing Wang

Pages: 289-297 Published online on: 01 November 2017

Silencing of vacuolar ATPase c subunit ATP6V0C inhibits the invasion of prostate cancer cells through a LASS2/TMSG1-independent manner

Pengcheng Zou, Yifeng Yang, Xiaoyan Xu, Beiying Liu, Fang Mei, Jiangfeng You, Qichen Liu, Fei Pei

Pages: 298-306 Published online on: 10 November 2017

The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer

Guodong Lian, Leping Li, Fei Ye, Daguang Wang, Jinglei Liu, Yulong Shi, Changqing Jing, Jian Suo, David Y. Zhang, Man Chen

Pages: 307-315 Published online on: 06 November 2017

Role of mitochondrial function in the invasiveness of human colon cancer cells

Chen-Sung Lin, Li-Tzu Liu, Liang-Hung Ou, Siao-Cian Pan, Chia-I Lin, Yau-Huei Wei

Pages: 316-330 Published online on: 09 November 2017

miR‑106b‑5p promotes cell cycle progression of malignant melanoma by targeting PTEN

Xu-Ε Chen, Pu Chen, Shan-Shan Chen, Ting Ma, Guang Shi, Ya Zhou, Ji Li, Liang Sheng

Pages: 331-337 Published online on: 16 November 2017

Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation

Yi-Ming Cao, Jun Gu, Yan-Shu Zhang, Wen-Jun Wei, Ning Qu, Duo Wen, Tian Liao, Rong-Liang Shi, Ling Zhang, Qing-Hai Ji, Yu Wang, Guo-Hua Sun, Yang-Xing Zhao, Yuan-Jin Wang, Jian Yu, Yong-Xue Zhu

Pages: 338-348 Published online on: 25 October 2017

NRP1-positive lung cancer cells possess tumor-initiating properties

Luis E. Jimenez-Hernandez, Karla Vazquez-Santillan, Rosario Castro-Oropeza, Gustavo Martinez-Ruiz, Laura Muñoz-Galindo, Carolina Gonzalez-Torres, Carlo C. Cortes-Gonzalez, Georgina Victoria-Acosta, Jorge Melendez-Zajgla, Vilma Maldonado

Pages: 349-357 Published online on: 09 November 2017

SPLUNC1 knockout enhances LPS-induced lung injury by increasing recruitment of CD11b+Gr-1+ cells to the spleen of mice

Han Zhang, Xiaoling Li, Shan Liao, Heran Wang, Pan Chen, Guangchao Zhu, Yanwei Luo, Guiyuan Li, Yanhong Zhou

Pages: 358-366 Published online on: 01 November 2017

Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells

Toshiyuki Nanbu, Naoki Umemura, Emika Ohkoshi, Kumi Nanbu, Hiroshi Sakagami, Jun Shimada

Pages: 367-375 Published online on: 21 November 2017

Liver kinase B1 restoration promotes exosome secretion and motility of lung cancer cells

Cheng Zhang, Xiang Xiao, Minyi Chen, Hitham Aldharee, Yanfang Chen, Weiwen Long

Pages: 376-382 Published online on: 09 November 2017

ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells

Jai-Sing Yang, Chao-Ying Lee, Hsin-Chung Cho, Chi-Cheng Lu, Sheng-Chu Kuo, Yen-Fang Wen, Fuu-Jen Tsai, Miau-Rong Lee, Shih-Chang Tsai

Pages: 383-391 Published online on: 09 November 2017

A potential role for hepcidin in obesity-driven colorectal tumourigenesis

Elisabeth Phillips, Richard D. Horniblow, Vikki Poole, Matthew Bedford, Douglas G. Ward, Amanda J. Kirkham, Jeremy Tomlinson, Tariq H. Iqbal, Chris Tselepis

Pages: 392-400 Published online on: 31 October 2017

MicroRNA-326 inhibits melanoma progression by targeting KRAS and suppressing the AKT and ERK signalling pathways

Kang Kang, Jing Zhang, Xiaoyun Zhang, Zhao Chen

Pages: 401-410 Published online on: 02 November 2017

Glioma stem cells and their non-stem differentiated glioma cells exhibit differences in mitochondrial structure and function

Eun-Jung Kim, Xiong Jin, Ock Ran Kim, Seok Won Ham, Sung-Hye Park, Hyunggee Kim

Pages: 411-416 Published online on: 02 November 2017

Enhanced activated T cell subsets in prostate cancer patients receiving iodine-125 low-dose-rate prostate brachytherapy

Makoto Kubo, Takefumi Satoh, Hiromichi Ishiyama, Ken-Ichi Tabata, Hideyasu Tsumura, Shoko Komori, Masatsugu Iwamura, Shiro Baba, Kazushige Hayakawa, Toshihiko Kawamura, Fumiya Obata

Pages: 417-424 Published online on: 13 November 2017

Fungal mannosylation enhances human papillomavirus 16 E7 therapeutic immunity against TC-1 tumors

Zonglin Wang, Cuihua Wei, Yanjun Zhang, Wei Wang, Zheng Zhou, Gengfu Xiao

Pages: 425-432 Published online on: 08 November 2017

Complementary actions of melatonin on angiogenic factors, the angiopoietin/Tie2 axis and VEGF, in co‑cultures of human endothelial and breast cancer cells

Alicia González-González, Alicia González, Carolina Alonso-González, Javier Menéndez-Menéndez, Carlos Martínez-Campa, Samuel Cos

Pages: 433-441 Published online on: 02 November 2017

Hypoxia induces differential expression patterns of osteopontin and CD44 in colorectal carcinoma

Gisela Wohlleben, Konstantin Hauff, Martin Gasser, Ana Maria Waaga-Gasser, Tanja Grimmig, Michael Flentje, Bülent Polat

Pages: 442-448 Published online on: 01 November 2017
Journal Cover

January 2018
Volume 39 Issue 1

Print ISSN: 1021-335X
Online ISSN: 1791-2431

2016 Impact Factor: 2.662
Ranked #31/217 Oncology
(total number of cites)

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