Journal Articles

Predicting resistance to endocrine therapy in breast cancer: It's time for epigenetic biomarkers (Review)

Mário Fontes‑Sousa, Maria Amorim, Sofia Salta, Susana Palma De Sousa, Rui Henrique, Carmen Jerónimo

Pages: 1431-1438 Published online on: 11 January 2019

MicroRNAs and the PTEN/PI3K/Akt pathway in gastric cancer (Review)

Mingli Hu, Shixuan Zhu, Shengwei Xiong, Xingxing Xue, Xiaodong Zhou

Pages: 1439-1454 Published online on: 10 January 2019

Ubiquitination‑deubiquitination in the Hippo signaling pathway (Review)

Yanting Liu, Jun Deng

Pages: 1455-1475 Published online on: 08 January 2019
Open Access

Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells

Vincenzo Quagliariello, Mario Masarone, Emilia Armenia, Aldo Giudice, Manlio Barbarisi, Michele Caraglia, Alfonso Barbarisi, Marcello Persico

Pages: 1476-1486 Published online on: 13 December 2018
Open Access

Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein

Jinqi Ma, Weihong Niu, Xinye Wang, Yao Zhou, Heran Wang, Fengxia Liu, Yukun Liu, Jie Guo, Wei Xiong, Zhaoyang Zeng, Songqing Fan, Xiaoling Li, Xinmin Nie, Guiyuan Li, Rong Gui, Yanwei Luo, Ming Zhou

Pages: 1487-1496 Published online on: 21 December 2018
Open Access

MicroRNA‑200a suppresses migration and invasion and enhances the radiosensitivity of NSCLC cells by inhibiting the HGF/c‑Met signaling pathway

Menghua Du, Jin Wang, Huan Chen, Shouli Wang, Liesong Chen, Yichang Xu, Fengtao Su, Xueguan Lu

Pages: 1497-1508 Published online on: 12 December 2018
Open Access

SOCS4 expressed by recombinant HSV protects against cytokine storm in a mouse model

Shuqi Ren, Xiaoqing Chen, Rongquan Huang, Grace Guoying Zhou, Zhuqing Yuan

Pages: 1509-1520 Published online on: 18 December 2018
Open Access

A 6‑gene risk score system constructed for predicting the clinical prognosis of pancreatic adenocarcinoma patients

Yan Liu, Dongyan Zhu, Hongjian Xing, Yi Hou, Yan Sun

Pages: 1521-1530 Published online on: 22 January 2019
Open Access

CTHRC1 overexpression promotes cervical carcinoma progression by activating the Wnt/PCP signaling pathway

Mei Zheng, Qin Zhou, Xingguang Liu, Chengze Wang, Gangli Liu

Pages: 1531-1538 Published online on: 10 January 2019
Open Access

Peroxiredoxin2 downregulation enhances hepatocellular carcinoma proliferation and migration, and is associated with unfavorable prognosis in patients

Bing Bai, Yanyan Lin, Jinjing Hu, Haiping Wang, Lu Li, Sheng Zhao, Jinduo Zhang, Wenbo Meng, Ping Yue, Zhongtian Bai, Xun  Li

Pages: 1539-1548 Published online on: 22 January 2019
Open Access

miRNA-223 is an anticancer gene in human non-small cell lung cancer through the PI3K/AKT pathway by targeting EGFR

Hui-Ping Ma, Wei-Xiang Kong, Xiu-Ying Li, Wei Li, Yan Zhang, Yan Wu

Pages: 1549-1559 Published online on: 24 January 2019
Open Access

Pilot investigation of the mutation profile of PIK3CA/PTEN genes (PI3K pathway) in grade 3 endometrial cancer

Francesca Malentacchi, Irene Turrini, Flavia Sorbi, Elisabetta Projetto, Francesca Castiglione, Massimiliano Fambrini, Felice Petraglia, Serena Pillozzi, Ivo Noci

Pages: 1560-1574 Published online on: 18 December 2018
Open Access

miR‑107‑5p promotes tumor proliferation and invasion by targeting estrogen receptor‑α in endometrial carcinoma

Wei Bao, Yan Zhang, Shuangdi Li, Qiong Fan, Meiting Qiu, Yanan Wang, Yanli Li, Xiaoning Ji, Ye Yang, Zhenyu Sang, Wei Xu, Yongbin Yang, Sufang Wu, Yaping Zhu

Pages: 1575-1585 Published online on: 18 December 2018
Open Access

Identification of prognostic biomarkers for patients with hepatocellular carcinoma after hepatectomy

Xiangkun Wang, Xiwen Liao, Chengkun Yang, Ketuan Huang, Tingdong Yu, Long Yu, Chuangye Han, Guangzhi Zhu, Xianmin Zeng, Zhengqian Liu, Xin Zhou, Wei Qin, Hao Su, Xinping Ye, Tao Peng

Pages: 1586-1602 Published online on: 03 January 2019
Open Access

ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer

Lili Guo, Lili Ma, Chao Liu, Yan Lei, Na Tang, Yingxin Huang, Guan Huang, Dazhou Li, Qi Wang, Guanglong Liu, Minshan Tang, Zhiliang Jing, Yongjian Deng

Pages: 1603-1615 Published online on: 19 December 2018
Open Access

Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress

Jung Lim Kim, Dae‑Hee Lee, Soyeon Jeong, Bo Ram Kim, Yoo Jin Na, Seong Hye Park, Min Jee Jo, Yoon A. Jeong, Sang Cheul Oh

Pages: 1616-1626 Published online on: 19 December 2018
Open Access

MicroRNA‑21 regulates the biological behavior of esophageal squamous cell carcinoma by targeting RASA1

Xiaohua Chen, Sina Cai, Baoxia Li, Xiaona Zhang, Wenhui Li, Henglun Liang, Xiaolong Cao, Liping Wang, Ziqing Wu

Pages: 1627-1637 Published online on: 19 December 2018
Open Access

miR‑498 inhibits the growth and metastasis of liver cancer by targeting ZEB2

Xu Zhang, Xueying Xu, Guohong Ge, Xueyan Zang, Meng Shao, Shengqiang Zou, Yu Zhang, Zheying Mao, Jiayin Zhang, Fei Mao, Hui Qian, Wenrong Xu

Pages: 1638-1648 Published online on: 21 December 2018
Open Access

SHCBP1 is a novel target and exhibits tumor‑promoting effects in gastric cancer

Ya‑Dong Dong, Yan‑Li Yuan, Hai‑Bo Yu, Guang‑Jin Tian, De‑Yu Li

Pages: 1649-1657 Published online on: 21 December 2018
Open Access

Electrochemotherapy of radioresistant head and neck squamous cell carcinoma cells and tumor xenografts

Martina Niksic Zakelj, Ajda Prevc, Simona Kranjc, Maja Cemazar, Vesna Todorovic, Monika Savarin, Janez Scancar, Tina Kosjek, Blaz Groselj, Primoz Strojan, Gregor Sersa

Pages: 1658-1668 Published online on: 09 January 2019
Open Access

MicroRNA‑3653 inhibits the growth and metastasis of hepatocellular carcinoma by inhibiting ITGB1

Lijuan Zhang, Tao Zhang, Zerun Deng, Lihua Sun

Pages: 1669-1677 Published online on: 16 January 2019
Open Access

Downregulation of PRMT1, a histone arginine methyltransferase, by sodium propionate induces cell apoptosis in colon cancer

Tae Young Ryu, Kwangkho Kim, Mi-Young Son, Jeong-Ki Min, Janghwan Kim, Tae-Su Han, Dae-Soo Kim, Hyun-Soo Cho

Pages: 1691-1699 Published online on: 18 December 2018
Open Access

Gambogenic acid inhibits the proliferation of small‑cell lung cancer cells by arresting the cell cycle and inducing apoptosis

Tingting Huang, Hongming Zhang, Xiyong Wang, Lu Xu, Jinfang Jia, Xiaoli Zhu

Pages: 1700-1706 Published online on: 21 December 2018
Open Access

miR‑29a ameliorates ischemic injury of astrocytes in vitro by targeting the water channel protein aquaporin 4

Yueying Zheng, Caifei Pan, Manli Chen, Aijie Pei, Liwei Xie, Shengmei Zhu

Pages: 1707-1717 Published online on: 09 January 2019
Open Access

miR663a‑TTC22V1 axis inhibits colon cancer metastasis

Wei Tian, Yantao Du, Yuwan Ma, Baozhen Zhang, Liankun Gu, Jing Zhou, Dajun Deng

Pages: 1718-1728 Published online on: 16 January 2019

Integrating modern approaches to pathogenetic concepts of malignant transformation of endometriosis

Hiroshi Kobayashi, Yuki Yamada, Naoki Kawahara, Kenji Ogawa, Chiharu Yoshimoto

Pages: 1729-1738 Published online on: 21 December 2018

Upregulation of USP11 promotes epithelial‑to‑mesenchymal transition by deubiquitinating Snail in ovarian cancer

Weiwei Wang, Jing Wang, Hua Yan, Kai Zhang, Yang Liu

Pages: 1739-1748 Published online on: 12 December 2018

Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma

Bo Jia, Xiaoling Qiu, Hongxing Chu, Xiang Sun, Shuaimei Xu, Xinyuan Zhao, Jianjiang Zhao

Pages: 1749-1758 Published online on: 22 January 2019

Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway

Tingxiu Zhang, Lijie Ma, Pengfei Wu, Wei Li, Ting Li, Rui Gu, Xiaoping Dan, Zhiwei Li, Xianming Fan, Zhenliang Xiao

Pages: 1779-1788 Published online on: 22 January 2019

Downregulated Krüppel‑like factor 4 expression is associated with the aggressiveness of prostate cancer

Neng Zhang, Peng Su, Xiaoguang Li, Jianming Xi, Xu Li, Luo Xu

Pages: 1789-1796 Published online on: 22 January 2019

lncRNA CASC2/miR‑18a‑5p axis regulates the malignant potential of nasopharyngeal carcinoma by targeting RBBP8

Wen‑Jie Miao, Dong‑Jie Yuan, Guo‑Zheng Zhang, Qi Liu, Hui‑Min Ma, Qian‑Qian Jin

Pages: 1797-1806 Published online on: 19 December 2018

Cytoplasmic M‑CSF facilitates apoptosis resistance by inhibiting the HIF‑1α/BNIP3/Bax signalling pathway in MCF‑7 cells

Mengxia Zhang, Qi Liu, Lijun Li, Jing Ning, Jian Tu, Xiaoyong Lei, Zhongcheng Mo, Shengsong Tang

Pages: 1807-1816 Published online on: 21 December 2018

Effect of NELL1 on lung cancer stem‑like cell differentiation

Yuanfen Zhai, Rongbin Wei, Shuang Sha, Chengzhao  Lin, Heyong Wang, Xinquan Jiang, Gentao Liu

Pages: 1817-1826 Published online on: 03 January 2019

PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma

Yu Cao, Han Liu, Shi‑Lin Xia, Xi Zhang, Han Bai, Qian Yang, Jiang Li, Liwei Gao, Feng Jin, Min‑Jie Wei, Shi‑Long Lu, Jing Xiao

Pages: 1827-1836 Published online on: 13 December 2018

Kenalog modified by ionizing radiation induces intrinsic apoptosis mediated by elevated levels of reactive oxygen species in melanoma cancer

Remigius Ambrose Kawala, Fatuma Jumapili Ramadhani, Hyo Jin Choi, Eun‑Hee Lee, Chul‑Hong Park, Byung Yeoup Chung, Hyoung‑Woo Bai

Pages: 1837-1850 Published online on: 19 December 2018

Biological characterisation and application of human MTH1 and monoclonal antibody preparation

Chuyuan Chen, Xiaoping Li, Mengyue Gu, Rongrong Di, Nannan Kang, Lei Wang, Yisheng Lai, Yu Liu, Xuemei Ji

Pages: 1851-1862 Published online on: 19 December 2018

Intravesical treatment of chemotherapeutic agents sensitizes bacillus Calmette‑Guerin by the modulation of the tumor immune environment

Shunta Hori, Makito Miyake, Yoshihiro Tatsumi, Yosuke Morizawa, Yasushi Nakai, Sayuri Onishi, Kenta Onishi, Kota Iida, Daisuke Gotoh, Yoshitaka Itami, Nobumichi Tanaka, Kiyohide Fujimoto

Pages: 1863-1874 Published online on: 10 January 2019

XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells

Xue Teng, Xiao‑Fan Fan, Qi Li, Shuang Liu, Dong‑Yuan Wu, Shu‑Ya Wang, Yuanqi Shi, Mei Dong

Pages: 1875-1882 Published online on: 09 January 2019

Momelotinib sensitizes glioblastoma cells to temozolomide by enhancement of autophagy via JAK2/STAT3 inhibition

Tie Liu, Anqi Li, Yulun Xu, Yu Xin

Pages: 1883-1892 Published online on: 16 January 2019

Expression profiles and potential functions of circular RNAs in extracellular vesicles isolated from radioresistant glioma cells

Mengjie Zhao, Jinjin Xu, Shanliang Zhong, Yuchi Liu, Hong Xiao, Liangyuan Geng, Hongyi Liu

Pages: 1893-1900 Published online on: 18 January 2019

Downregulation of BAG‑1 in T47D cells promotes resistance to tamoxifen via activation of the PI3K/Akt/mTOR signaling pathway

Su Lu, Yiyi Du, Fang Cui, Xinyi Feng, Yuanyuan Ma, Hong Liu

Pages: 1901-1910 Published online on: 22 January 2019

CX3CL1 promotes lung cancer cell migration and invasion via the Src/focal adhesion kinase signaling pathway

Wangmi Liu, Yun Liang, Qian Chan, Libo Jiang, Jian Dong

Pages: 1911-1917 Published online on: 09 January 2019

Interaction between C2ORF68 and HuR in human colorectal cancer

Zhaoxu Lv, Kunyan He, Lihong Shi, Kai Shi, Tingting Jiang, Yao Chen

Pages: 1918-1928 Published online on: 21 January 2019

Identification and validation of alternative splicing isoforms as novel biomarker candidates in hepatocellular carcinoma

Peng Wu, Donghu Zhou, Yuqian Wang, Weiran Lin, Aihua Sun, Handong Wei, Yi Fang, Xianling Cong, Ying Jiang

Pages: 1929-1937 Published online on: 21 December 2018

MicroRNA‑486‑5p functions as a tumor suppressor of proliferation and cancer stem‑like cell properties by targeting Sirt1 in liver cancer

Xinlong Yan, Xinhui Liu, Zhaohai Wang, Qian Cheng, Guanghong Ji, Hui Yang, Lingfei Wan, Chen Ge, Quan Zeng, Hua Huang, Jiafei Xi, Lijuan He, Xue Nan, Wen Yue, Xuetao Pei

Pages: 1938-1948 Published online on: 13 December 2018

PEA‑15 contributes to the clinicopathology and AKT‑regulated cisplatin resistance in gastric cancer

Xian Jiang, Changlu Zhang, Weidong Li, Dalei Jiang, Zheng Wei, Mei Lv, Xiangjun Xie, Xueying Sun

Pages: 1949-1959 Published online on: 18 December 2018

Radiosensitization of esophageal carcinoma cells by knockdown of HMGB1 expression

Xueyuan Zhang, Xingxiao Yang, Shuchai Zhu, Qiaofang Li, Naiyi Zou

Pages: 1960-1970 Published online on: 10 December 2018

Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy

Jiu‑Zhou Hou, Zhuo‑Qing Xi, Jie Niu, Wei Li, Xiao Wang, Chao Liang, Hua Sun, Dong Fang, Song‑Qiang Xie

Pages: 1971-1979 Published online on: 12 December 2018

The role of ZBTB38 in promoting migration and invasive growth of bladder cancer cells

Jingchen Jing, Jie Liu, Yaochun Wang, Miao Zhang, Lu Yang, Feiyu Shi, Peijun Liu, Junjun She

Pages: 1980-1990 Published online on: 18 December 2018

Combined inhibition of sonic Hedgehog signaling and histone deacetylase is an effective treatment for liver cancer

Jingmin Li, Heng Cai, Hongxing Li, Yanguo Liu, Yirong Wang, Yan Shi, Yan Sun, Haoran Song, Dong Wang

Pages: 1991-1997 Published online on: 23 January 2019

Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2

Yan Wang, Zihao Qi, Menglong Zhou, Wang Yang, Ran Hu, Guichao Li, Xuejun Ma, Zhen Zhang

Pages: 1998-2008 Published online on: 23 January 2019

17β‑hydroxysteroid dehydrogenase 4 induces liver cancer proliferation‑associated genes via STAT3 activation

Xin Lu, Lingyu Kong, Xi Wang, Weiran Liu, Panpan Ma, Lingling Jiang

Pages: 2009-2019 Published online on: 23 January 2019

Shikonin induces an anti‑tumor effect on murine mammary cancer via p38‑dependent apoptosis

Jiuxiang Xu, Keiichi Koizumi, Mengxin Liu, Yusuke Mizuno, Mikiko Suzaki, Hirofumi Iitsuka, Akiko Inujima, Makoto Fujimoto, Naotoshi Shibahara, Yutaka Shimada

Pages: 2020-2026 Published online on: 11 January 2019

Disruption of MAPK1 expression in the ERK signalling pathway and the RUNX1‑RUNX1T1 fusion gene attenuate the differentiation and proliferation and induces the growth arrest in t(8;21) leukaemia cells

Salem Ali Al‑Salem Bashanfer, Mohamed Saleem, Olaf Heidenreich, Emmanuel Jairaj Moses, Narazah Mohd Yusoff

Pages: 2027-2040 Published online on: 12 December 2018

Early decrease in serum amphiregulin or vascular endothelial growth factor levels predicts sorafenib efficacy in hepatocellular carcinoma

Corinne Godin, Sandra Bodeau, Zuzana Saidak, Christophe Louandre, Catherine François, Jean‑Claude Barbare, Romain Coriat, Antoine Galmiche, Chloé Sauzay

Pages: 2041-2050 Published online on: 10 December 2018

Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer

Chyou‑Wei Wei, Yung‑Luen Yu, Yu‑Hsun Chen, Yu‑Ting Hung, Giou‑Teng Yiang

Pages: 2060-2066 Published online on: 09 January 2019
Open Access

[Corrigendum] High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer

Ping Chen, Deshou Zhao, Weiyi Wang, Yongping Zhang, Yaozong Yuan, Lifu Wang, Yunlin Wu

Pages: 2067-2067 Published online on: 17 December 2018
Open Access

[Corrigendum] Oncogenic function of Plac1 on the proliferation and metastasis in hepatocellular carcinoma cells

Yuan Wu, Xiaocong Lin, Xiaoqing Di, Yonghua Chen, Hanning Zhao, Xin Wang

Pages: 2068-2068 Published online on: 04 January 2019
Journal Cover

March 2019
Volume 41 Issue 3

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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