Journal Articles
Epigenetic roles of PIWI‑interacting RNAs (piRNAs) in cancer metastasis (Review)
Jia Liu, Shujun Zhang, Binglin Cheng
Pages: 2423-2434 Published online on: 06 September 2018
3‑Bromopyruvate sensitizes human breast cancer cells to TRAIL‑induced apoptosis via the phosphorylated AMPK‑mediated upregulation of DR5
Yuzhong Chen, Li Wei, Xiaojing Zhang, Xianfu Liu, Yansong Chen, Song Zhang, Lanzhu Zhou, Qixiang Li, Qiong Pan, Surong Zhao, Hao Liu
Pages: 2435-2444 Published online on: 14 August 2018
CIP2A depletion potentiates the chemosensitivity of cisplatin by inducing increased apoptosis in bladder cancer cells
Fengbin Gao, Xiaojing Wang, Shanwen Chen, Tianyuan Xu, Xianjin Wang, Yifan Shen, Fan Dong, Shan Zhong, Zhoujun Shen
Pages: 2445-2454 Published online on: 10 August 2018
Generation of PTEN‑knockout (‑/‑) murine prostate cancer cells using the CRISPR/Cas9 system and comprehensive gene expression profiling
Akiko Takao, Kazuhiro Yoshikawa, Sivasundaram Karnan, Akinobu Ota, Hirotsugu Uemura, Marco A. De Velasco, Yurie Kura, Susumu Suzuki, Ryuzo Ueda, Tokiko Nishino, Yoshitaka Hosokawa
Pages: 2455-2466 Published online on: 05 September 2018
Risk assessment model constructed by differentially expressed lncRNAs for the prognosis of glioma
Chenggong Hu, Yongfang Zhou, Chang Liu, Yan Kang
Pages: 2467-2476 Published online on: 10 August 2018
Knockdown of POLE2 expression suppresses lung adenocarcinoma cell malignant phenotypes in vitro
Jianying Li, Juanhong Wang, Jun Yu, Yuling Zhao, Ya Dong, Yali Fan, Namiao Li, Yingying Zhang, Yili Wang
Pages: 2477-2486 Published online on: 17 August 2018
Cytoplasmic expression of SOX9 as a poor prognostic factor for oral squamous cell carcinoma
Yoshimasa Sumita, Manabu Yamazaki, Satoshi Maruyama, Tatsuya Abé, Jun Cheng, Ritsuo Takagi, Jun‑Ichi Tanuma
Pages: 2487-2496 Published online on: 22 August 2018
UCA1 overexpression is associated with less aggressive subtypes of bladder cancer
Laetitia Lebrun, Dina Milowich, Marie Le Mercier, Justine Allard, Yves‑Rémi Van Eycke, Thierry Roumeguere, Christine Decaestecker, Isabelle Salmon, Sandrine Rorive
Pages: 2497-2506 Published online on: 10 September 2018
lncRNA LINC01296 regulates the proliferation, metastasis and cell cycle of osteosarcoma through cyclin D1
Xin Yu, Lei Pang, Teng Yang, Pengcheng Liu
Pages: 2507-2514 Published online on: 30 August 2018
Identification of MMP9 as a novel key gene in mantle cell lymphoma based on bioinformatic analysis and design of cyclic peptides as MMP9 inhibitors based on molecular docking
Wei Yan, Shawn Xiang Li, Minjie Wei, Hua Gao
Pages: 2515-2524 Published online on: 05 September 2018
The role of 17β‑estradiol‑induced upregulation of Piwi‑like 4 in modulating gene expression and motility in breast cancer cells
Zealyn Shi Lin Heng, Jing Yi Lee, Charannya Sozheesvari Subhramanyam, Cheng Wang, Lal Zo Thanga, Qidong Hu
Pages: 2525-2535 Published online on: 31 August 2018
hsa‑miR‑24 suppresses metastasis in nasopharyngeal carcinoma by regulating the c‑Myc/epithelial‑mesenchymal transition axis
Bojin Su, Tao Xu, Jeff P. Bruce, Kenneth W. Yip, Ning Zhang, Zeli Huang, Guoyi Zhang, Fei‑Fei Liu, Jiyong Liang, Huiling Yang, François X. Claret
Pages: 2536-2546 Published online on: 07 September 2018
CRISPR/Cas9‑mediated hypoxia inducible factor‑1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma
Quan Liu, Dahua Fan, Dickson Adah, Zhengzhi Wu, Renyan Liu, Qiao‑Ting Yan, Yue Zhang, Zhi‑Yong Du, Dou Wang, Yan Li, Shi‑Yun Bao, Li‑Ping Liu
Pages: 2547-2557 Published online on: 23 August 2018
Tumor associated macrophages induce epithelial to mesenchymal transition via the EGFR/ERK1/2 pathway in head and neck squamous cell carcinoma
Lu Gao, Wei Zhang, Wen‑Qun Zhong, Zhuo‑Jue Liu, Hui‑Min Li, Zi‑Li Yu, Yi‑Fang Zhao
Pages: 2558-2572 Published online on: 17 August 2018
HOXA10‑AS: A novel oncogenic long non‑coding RNA in glioma
Cheng‑Ya Dong, Jiayue Cui, Dian‑He Li, Qi Li, Xin‑Yu Hong
Pages: 2573-2583 Published online on: 21 August 2018
Characterization of selective exosomal microRNA expression profile derived from laryngeal squamous cell carcinoma detected by next generation sequencing
Qiang Huang, Jiechao Yang, Juan Zheng, Chiyao Hsueh, Yang Guo, Liang Zhou
Pages: 2584-2594 Published online on: 24 August 2018
Interaction of hematopoietic CD34+ CD45+ stem cells and cancer cells stimulated by TGF‑β1 in a model of glioblastoma in vitro
Elena Milkina, Arina Ponomarenko, Maria Korneyko, Irina Lyakhova, Yulia Zayats, Sergey Zaitsev, Polina Mischenko, Marina Eliseikina, Yuri Khotimchenko, Valeryi Shevchenko, Hari Sharma, Igor Bryukhovetskiy
Pages: 2595-2607 Published online on: 24 August 2018
KLF5 promotes the tumorigenesis and metastatic potential of thyroid cancer cells through the NF-κB signaling pathway
Yuehua Ma, Qingzhu Wang, Fei Liu, Xiaojun Ma, Lina Wu, Feng Guo, Shuiying Zhao, Fengjuan Huang, Guijun Qin
Pages: 2608-2618 Published online on: 06 September 2018
STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2
Sirichat Kaowinn, Chutima Kaewpiboon, Sang Seok Koh, Oliver H. Krämer, Young‑Hwa Chung
Pages: 2619-2627 Published online on: 12 September 2018
Upregulation of macrophage migration inhibitory factor promotes tumor metastasis and correlates with poor prognosis of pancreatic ductal adenocarcinoma
Dong Wang, Ruizhi Wang, Anpei Huang, Zeng Fang, Kebing Wang, Meifang He, Jin‑Tang Xia, Wen Li
Pages: 2628-2636 Published online on: 12 September 2018
An integrated methylation and gene expression microarray analysis reveals significant prognostic biomarkers in oral squamous cell carcinoma
Chenguang Zhao, Huiru Zou, Jun Zhang, Jinhui Wang, Hao Liu
Pages: 2637-2647 Published online on: 12 September 2018
Biological functions and clinical significance of the newly identified long non‑coding RNA RP1‑85F18.6 in colorectal cancer
Yeshuo Ma, Yifei Chen, Changwei Lin, Gui Hu
Pages: 2648-2658 Published online on: 10 September 2018
Prediction of candidate RNA signatures for recurrent ovarian cancer prognosis by the construction of an integrated competing endogenous RNA network
Xin Wang, Lei Han, Ling Zhou, Li Wang, Lan‑Mei Zhang
Pages: 2659-2673 Published online on: 13 September 2018
Regulatory mechanism of fatty acid‑CoA metabolic enzymes under endoplasmic reticulum stress in lung cancer
Kuan‑Ting Liu, I‑Jeng Yeh, Shih‑Kai Chou, Meng‑Chi Yen, Po‑Lin Kuo
Pages: 2674-2682 Published online on: 21 August 2018
MALAT1 promotes angiogenesis of breast cancer
Xiao‑Juan Huang, Yu Xia, Gui‑Fang He, Lu‑Lu Zheng, Yong‑Ping Cai, Yu Yin, Qiang Wu
Pages: 2683-2689 Published online on: 13 September 2018
EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFR‑positive cancer cells
Saeed M. Hashimi, Brock Grant, Naif Alqurashi, Faisal Alowaidi, Ming Q. Wei
Pages: 2690-2697 Published online on: 06 September 2018
Low expression of LINC00982 and PRDM16 is associated with altered gene expression, damaged pathways and poor survival in lung adenocarcinoma
Wenwen Lv, Xiao Yu, Wenxing Li, Nannan Feng, Tienan Feng, Yu Wang, Hongyan Lin, Biyun Qian
Pages: 2698-2709 Published online on: 14 August 2018
miR‑197 promotes the invasion and migration of colorectal cancer by targeting insulin‑like growth factor‑binding protein 3
Na Zhou, Zhao Sun, Ningning Li, Yuping Ge, Jianfeng Zhou, Qin Han, Lin Zhao, Chunmei Bai
Pages: 2710-2721 Published online on: 10 August 2018
B7‑H3 promotes malignant progression of muscle‑invasive bladder cancer
Zhi‑Li Xu, Yi Zhang, Ling Wang, Feng Li, Hong‑Wei Man, Peng‑Fei Li, Bao‑En Shan
Pages: 2722-2733 Published online on: 17 August 2018
C‑C chemokine receptor type 2 promotes epithelial‑to‑mesenchymal transition by upregulating matrix metalloproteinase‑2 in human liver cancer
Huijin Li, Hui Li, Xiao‑Peng Li, Haojun Zou, Liting Liu, Wangqiao Liu, Tao Duan
Pages: 2734-2741 Published online on: 17 August 2018
APOBEC3B is expressed in human glioma, and influences cell proliferation and temozolomide resistance
Christina Schmitt, Ralph Lucius, Michael Synowitz, Janka Held‑Feindt, Kirsten Hattermann
Pages: 2742-2749 Published online on: 10 September 2018
MicroRNA‑342‑3p suppresses proliferation and invasion of nasopharyngeal carcinoma cells by directly targeting Cdc42
Lu Shi, Ruowen Xiao, Menghe Wang, Meiyin Zhang, Nuoqing Weng, Xinge Zhao, X.f. Steven Zheng, Huiyun Wang, Shijuan Mai
Pages: 2750-2757 Published online on: 10 August 2018
Resveratrol inhibited the progression of human hepatocellular carcinoma by inducing autophagy via regulating p53 and the phosphoinositide 3‑kinase/protein kinase B pathway
Baichao Zhang, Xiaoning Yin, Shaoguang Sui
Pages: 2758-2765 Published online on: 17 August 2018
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals
Pei‑Jing Yang, Ming‑Feng Hou, Eing‑Mei Tsai, Shih‑Shin Liang, Chien‑Chih Chiu, Fu Ou‑Yang, Jung‑Yu Kan, Chiung‑Yu Peng, Tsu‑Nai Wang
Pages: 2766-2777 Published online on: 30 August 2018
Low expression of BEX1 predicts poor prognosis in patients with esophageal squamous cell cancer
Hai‑Tao Geng, Zhi‑Wen Cheng, Rui‑Juan Cao, Zhen‑Bo Wang, Shao‑Zhi Xing, Chen Guo, Feng Wang, Chang‑Min Liu, Shao‑Shui Chen, Yu‑Feng Cheng
Pages: 2778-2787 Published online on: 17 August 2018
Lactate dehydrogenase is correlated with clinical stage and grade and is downregulated by si‑SAΤB1 in ovarian cancer
Jiangdong Xiang, Lina Zhou, Yan Zhuang, Jin Zhang, Ya Sun, Shuangdi Li, Zhenbo Zhang, Gao Zhang, Yinyan He
Pages: 2788-2797 Published online on: 17 August 2018
Inhibition of miR‑21 promotes cell apoptosis in oral squamous cell carcinoma by upregulating PTEN
Yanliang Zheng, Jingfang Xie, Fangfang Jiang, Yunyun Li, Guanlin Chang, Haiqing Ma
Pages: 2798-2805 Published online on: 21 August 2018
miR‑20b negatively regulates VEGF expression by targeting STAT3 in H22 hepatocellular carcinoma cells
Yulan Luo, Jing He, Xiangnan Tao, Helong Wang, Qiang Fang, Shujun Guo, Chuanwang Song
Pages: 2806-2813 Published online on: 17 August 2018
Long non-coding RNA MYU promotes prostate cancer proliferation by mediating the miR-184/c-Myc axis
Jinhua Wang, Xiaohui Yang, Rong Li, Liang Wang, Yinmin Gu, Yuhui Zhao, Kuo Hsiang Huang, Tianyou Cheng, Yi Yuan, Shan Gao
Pages: 2814-2825 Published online on: 20 August 2018
A novel clinical multidimensional transcriptome signature predicts prognosis in bladder cancer
Chun‑Peng Liu, Jian‑Hua Zhang, Shuai‑Chao Zheng, Jing Liu, Jin‑Cheng Guo
Pages: 2826-2835 Published online on: 31 August 2018
2'‑Hydroxyflavanone inhibits epithelial‑mesenchymal transition, and cell migration and invasion via suppression of the Wnt/β‑catenin signaling pathway in prostate cancer
Shiqi Wu, Jun Huang, Ke Hui, Yangyang Yue, Yanan Gu, Zhongyun Ning, Xinyang Wang, Dalin He, Kaijie Wu
Pages: 2836-2843 Published online on: 31 August 2018
Inhibition of epithelial‑mesenchymal transition in gastric cancer cells by miR‑711‑mediated downregulation of CD44 expression
Wei‑Sheng Xiao, De‑Feng Li, Ya‑Ping Tang, Yan‑Zhu Chen, Wen‑Bing Deng, Juan Chen, Wei‑Wei Zhou, Ai‑Jun Liao
Pages: 2844-2853 Published online on: 04 September 2018
Dermcidin as a novel binding protein of lncRNA STCAT3 and its effect on prognosis in gastric cancer
Jianfeng Zhang, Weifeng Ding, Xiaoling Kuai, Yimin Ji, Zhenglong Zhu, Zhenbiao Mao, Zhiwei Wang
Pages: 2854-2863 Published online on: 24 August 2018
Effects of microRNA‑125b on multiple myeloma cell growth in vitro and in vivo
Yanxia Jiang, Jianghua Ding, Jing Li, Guoan Chen
Pages: 2864-2875 Published online on: 23 August 2018
TAB3 promotes human esophageal squamous cell carcinoma proliferation and invasion via the NF‑κB pathway
Jiyi Zhao, Ling Gai, Yi Gao, Wenkai Xia, Dong Shen, Qingfeng Lin, Weidong Mao, Fangjun Wang, Pengfei Liu, Jie Chen
Pages: 2876-2885 Published online on: 06 September 2018
Sinomenine hydrochloride sensitizes cervical cancer cells to ionizing radiation by impairing DNA damage response
Dan Zhang, Yiping Dong, Ying Zhao, Congya Zhou, Yuanjie Qian, Muralidhar L. Hegde, Haibo Wang, Suxia Han
Pages: 2886-2895 Published online on: 10 September 2018
18F‑alfatide positron emission tomography may predict anti‑angiogenic responses
Jie Liu, Dongxu Wang, Xue Meng, Xindong Sun, Shuanghu Yuan, Jinming Yu
Pages: 2896-2905 Published online on: 10 September 2018
Prognostic value of monocarboxylate transporter 4 in patients with esophageal squamous cell carcinoma
Bo Cheng, Xuan Chen, Yankang Li, Xiaochen Huang, Jinming Yu
Pages: 2906-2915 Published online on: 13 September 2018
The interaction between miR‑148a and DNMT1 suppresses cell migration and invasion by reactivating tumor suppressor genes in pancreatic cancer
Le Hong, Gen Sun, Long Peng, Yi Tu, Zhen Wan, Haiwei Xiong, Yong Li, Weidong Xiao
Pages: 2916-2925 Published online on: 12 September 2018
Cryptotanshinone inhibits cellular proliferation of human lung cancer cells through downregulation ofIGF-1R/PI3K/Akt signaling pathway
Jingtao Zhang, Guilan Wen, Longhua Sun, Wenxin Yuan, Ran Wang, Qinghua Zeng, Guangyi Zhang, Bentong Yu
Pages: 2926-2934 Published online on: 10 August 2018
A novel peptide targets CD105 for tumour imaging in vivo
Xiaolong Li, Xiaofeng Huang, Jing Zhang, Hongxing Huang, Long Zhao, Mei Yu, Yan Zhang, Hua Wang
Pages: 2935-2943 Published online on: 14 August 2018
MicroRNA‑145 inhibits migration and induces apoptosis in human non‑small cell lung cancer cells through regulation of the EGFR/PI3K/AKT signaling pathway
Bin Li, Cui‑Min Ding, Yan‑Xiao Li, Jing‑Cui Peng, Nan Geng, Wen‑Wen Qin
Pages: 2944-2954 Published online on: 23 August 2018
miR‑21‑5p targets PDHA1 to regulate glycolysis and cancer progression in gastric cancer
Zhuo Liu, Miao Yu, Bingyuan Fei, Xuedong Fang, Tonghui Ma, Dongxin Wang
Pages: 2955-2963 Published online on: 10 September 2018
Profile and validation of dysregulated long non‑coding RNAs and mRNAs in ovarian cancer
Yan‑Ming Lu, Yue Wang, Shi‑Qi Liu, Meng‑Ya Zhou, Ya‑Ru Guo
Pages: 2964-2976 Published online on: 17 August 2018
C16‑ceramide and sphingosine 1‑phosphate/S1PR2 have opposite effects on cell growth through mTOR signaling pathway regulation
Min Hee Kim, Joo‑Won Park, Eun‑Ji Lee, Shin Kim, Sun‑Hye Shin, Jung‑Hyuck Ahn, Yunjae Jung, Inkeun Park, Woo‑Jae Park
Pages: 2977-2987 Published online on: 07 September 2018
Downregulation of DLL4 predicts poor survival in non‑small cell lung cancer patients due to promotion of lymph node metastasis
Hongzhou Liu, Jie Peng, Meizhen Zhao, Pei Ma, Jun Zhong, Shuang Li, Zhongxin Lu
Pages: 2988-2996 Published online on: 31 August 2018
Increasing HER2 α2,6 sialylation facilitates gastric cancer progression and resistance via the Akt and ERK pathways
Naihua Liu, Menglu Zhu, Yingjie Linhai, Yuwei Song, Xiujuan Gui, Guoqiang Tan, Jinyuan Li, Yan Liu, Zhendong Deng, Xiaoting Chen, Jing Wang, Lili Jia, Xiuzhen He, Xiaoyu Wang, Shaoqiang Lin
Pages: 2997-3005 Published online on: 31 August 2018
Human umbilical vein endothelial cell vaccine suppresses the angiogenesis of esophageal squamous cell carcinoma in a humanized mouse model
Hangfan Liu, Jimin Zhao, Yi Yang, Guoguo Jin, Xiaoyan Zhang, Dongyu Wang, Chao Xie, Kangdong Liu, Xinhuan Chen, Xiang Li, Fang Tian, Ziming Dong, Jing Lu
Pages: 3006-3014 Published online on: 17 August 2018
Norepinephrine enhances cell viability and invasion, and inhibits apoptosis of pancreatic cancer cells in a Notch‑1‑dependent manner
Weikun Qian, Shifang Lv, Jie Li, Ke Chen, Zhengdong Jiang, Liang Cheng, Cancan Zhou, Bin Yan, Junyu Cao, Qingyong Ma, Wanxing Duan
Pages: 3015-3023 Published online on: 10 September 2018
Antitumor activity of the plant extract morin in tongue squamous cell carcinoma cells
Yawen Ji, Linglu Jia, Yunpeng Zhang, Yixiao Xing, Xuan Wu, Bin Zhao, Dondjiao Zhang, Xin Xu, Xu Qiao
Pages: 3024-3032 Published online on: 17 August 2018
Serum‑free‑medium‑type mesenchymal stem cell culture supernatant exerts a protective effect on A549 lung epithelial cells in acute lung injury induced by H2O2
Jian Wu, An‑Quan Shang, Chu Chen, Wei‑Wei Wang, Cun‑Quan Xiong, Nai‑Zhou Guo
Pages: 3033-3039 Published online on: 17 August 2018
Circadian clock gene Per2 downregulation in non‑small cell lung cancer is associated with tumour progression and metastasis
Run Xiang, Yue Cui, Yanping Wang, Tianpeng Xie, Xiaojun Yang, Zhu Wang, Juan Li, Qiang Li
Pages: 3040-3048 Published online on: 13 September 2018
Overexpression of Epsin 3 enhances migration and invasion of glioma cells by inducing epithelial‑mesenchymal transition
Yaru Wang, Wen Song, Pengcheng Kan, Chao Huang, Zhuolin Ma, Qiaoli Wu, Xiuhua Yao, Biao Zhang
Pages: 3049-3059 Published online on: 10 September 2018
Allergen‑removed Rhus verniciflua Stokes suppresses invasion and migration of pancreatic cancer cells through downregulation of the JAK/STAT and Src/FAK signaling pathways
Youra Kang, Seong Woo Yoon, Byoungduck Park
Pages: 3060-3068 Published online on: 12 September 2018
Lysines 207 and 325 methylation of WDR5 catalyzed by SETD6 promotes breast cancer cell proliferation and migration
Ruosi Yao, Yingli Wang, Danyang Han, Yuhui Ma, Musong Ma, Yaping Zhao, Jiang Tan, Jun Lu, Guiying Xu, Xiaoxue Li
Pages: 3069-3077 Published online on: 23 August 2018
Clinical relevance of the multidrug resistance‑associated protein 1 gene in non‑small cell lung cancer: A systematic review and meta‑analysis
Penghui Hu, Patrick Ting‑Yat Wong, Qinghua Zhou, Lianghe Sheng, Wenbo Niu, Size Chen, Meng Xu, Yiguang Lin
Pages: 3078-3091 Published online on: 17 August 2018
microRNA‑572 functions as an oncogene and a potential biomarker for renal cell carcinoma prognosis
Xiang Pan, Zuwei Li, Liwen Zhao, Jing Quan, Liang Zhou, Jinling Xu, Weiji Xu, Xin Guan, Hang Li, Shangqi Yang, Yaoting Gui, Yongqing Lai
Pages: 3092-3101 Published online on: 17 August 2018
Tanshinone IIA can inhibit MiaPaCa‑2 human pancreatic cancer cells by dual blockade of the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways
Chin‑Cheng Su
Pages: 3102-3111 Published online on: 23 August 2018
[Retracted] Long non‑coding RNA MALAT1 interacts with miR‑124 and modulates tongue cancer growth by targeting JAG1
Tong‑Han Zhang, Li‑Zhong Liang, Xiao‑Ling Liu, Ji‑Nan Wu, Kui Su, Jue‑Yao Chen, Qiao‑Yi Zheng, Hong‑Zhang Huang, Gui‑Qing Liao
Pages: 3112-3112 Published online on: 06 September 2018
