Journal Articles

Article Open Access

Neonatal intensive care unit on‑site surgery for congenital diaphragmatic hernia

Alina Elena Gaiduchevici, Cătălin Gabriel Cîrstoveanu, Bogdan Socea, Ana Mihaela Bizubac, Carmen Mariana Herișeanu, Cristina Filip, Florin Dumitru Mihălțan, Mihai Dimitriu, Florentina Jacotă‑Alexe, Mihail Ceaușu, Radu-Iulian Spătaru

Article Number: 436 Published online on: 10 May 2022
Article Open Access

FOXP2 regulates thyroid cancer cell proliferation and apoptosis via transcriptional activation of RPS6KA6

Feibiao Yang, Zhangsheng Xiao, Songze Zhang

Article Number: 434 Published online on: 09 May 2022
Case Report

Positive therapy outcome of lung squamous cell cancer: A case report

Ying Liu, Jian Yang, Xue-Jia Sun, Sheng-Nan Lu, Shi Liu

Article Number: 433 Published online on: 09 May 2022
Article Open Access

Tauroursodeoxycholic acid inhibits TGF‑β1‑induced renal fibrosis markers in cultured renal mesangial cells by regulating endoplasmic reticulum stress

Li Li, Zhi-Yun Guo, Juan Wang, Pei-Pei Fei, Yan-Fei Ji, Cheng-Gang Xu

Article Number: 432 Published online on: 09 May 2022
Case Report Open Access

Imaging analysis of the malignant transformation of bile duct hamartomas in the liver: A case report and literature review

Yuan Yuan, Gang Fu, Feng Wan, Xu-Lei Chen, Jun Feng

Article Number: 431 Published online on: 09 May 2022
Review Open Access

Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review)

Jianfeng He, Danyong Liu, Lixia Zhao, Dongcheng Zhou, Jianhui Rong, Liangqing Zhang, Zhengyuan Xia

Article Number: 430 Published online on: 06 May 2022
Article Open Access

Expression of yes‑associated protein, β‑catenin and smoothened, and their clinical significance in invasive breast cancer

Pengju Liu, Jianfeng Zeng, Gaohua Yang

Article Number: 429 Published online on: 06 May 2022
Article Open Access

Naringenin upregulates GTPCH1/eNOS to ameliorate high glucose‑induced retinal endothelial cell injury

Bing Xue, Yu Wang

Article Number: 428 Published online on: 05 May 2022
Article Open Access

Effect of ginkgolide K on calcium channel activity in Alzheimer's disease

Hongbin Liu, Qinyun Li, Xiaodan Zhang, Yun Shi, Jinyi Li

Article Number: 426 Published online on: 05 May 2022
Article Open Access

LincRNA‑EPS increases TGF‑β expression to inhibit the Wnt/β‑catenin pathway, VSMC osteoblastic differentiation and vascular calcification in diabetic mice

Yibo Li, Ziwei Xi, Zheng Yu, Chaoyue Yang, Chunhua Tan

Article Number: 425 Published online on: 04 May 2022
Review Open Access

COVID‑19: Main findings after a year and half of unease and the proper scientific progress (Review)

Marius Traian Leretter, Dan Dumitru Vulcanescu, Florin George Horhat, Anamaria Matichescu, Mircea Rivis, Laura-Cristina Rusu, Alexandra Roi, Robert Racea, Ioana Badea, Cristina Adriana Dehelean, Alexandra Mocanu, Delia Ioana Horhat

Article Number: 424 Published online on: 04 May 2022
Review Open Access

New approaches in ovarian cancer based on genetics and carcinogenesis hypotheses (Review)

Raluca Ana‑Μaria Mogos, Razvan Popovici, Adina Elena Tanase, Tudor Calistru, Paula Popovici, Mihaela Grigore, Alexandru Carauleanu

Article Number: 423 Published online on: 04 May 2022
Article Open Access

Anisodamine hydrobromide ameliorates cardiac damage after resuscitation

Gui-Juan Dong, Jun Yang, Xin Zhao, Shu-Bin Guo

Article Number: 422 Published online on: 03 May 2022
Article Open Access

Lenalidomide improves H2O2‑induced PC12 cell injury by blocking the Notch signaling pathway

Zheng Lv, Shao Yin, Ziguan Cheng, Kekai Wang

Article Number: 421 Published online on: 29 April 2022
Case Report Open Access

Reconstructive challenges of sinonasal tumors: A case report

Dragos Octavian Palade, Razvan Hainarosie, Mihaela Pertea, Florin Anghelina, Petronela Zaharia, Cătălina Pietroșanu, Valentin Calu, Valeriu Ardeleanu, Felicia Manole

Article Number: 419 Published online on: 29 April 2022
Article Open Access

Differential impact of the angiotensin‑converting enzyme‑2 (ACE2 rs4343 G>A) and miR‑196a2 rs11614913 C>T gene alterations in COVID‑19 disease severity and mortality

Mohammad Muzaffar Mir, Rashid Mir, Mushabab Ayed Abdullah Alghamdi, Badr Abdulmohsin Alsayed, Imadeldin Elfaki, Ali Al Bshabshe, Rabia Farooq, Muhanad Alhujaily, Muffarah Hamid Alharthi, Mohannad Mohammad S. Alamri, Abdullah M. Al‑Shahrani

Article Number: 418 Published online on: 29 April 2022
Article

Inonotsuoxide B suppresses hepatic stellate cell activation and proliferation via the PI3K/AKT and ERK1/2 pathway

Juan Jin, Hui Yang, Lili Hu, Yinghong Wang, Wenyong Wu, Chengmu Hu, Kun Wu, Zehua Wu, Wenming Cheng, Yan Huang

Article Number: 417 Published online on: 28 April 2022
Review Open Access

Clinical challenges of SARS‑CoV‑2 variants (Review)

Cristian Cojocaru, Elena Cojocaru, Adina Magdalena Turcanu, Dragos Cosmin Zaharia

Article Number: 416 Published online on: 28 April 2022
Case Report Open Access

Painless aortic dissection presenting as pseudo ileus: A case report

Chunhua Wang, Bo Wang, Zanmei Lv, Jia Zhi, Jie Yang, Yuqing Hao

Article Number: 415 Published online on: 27 April 2022
Article Open Access

Resveratrol protects against atherosclerosis by downregulating the PI3K/AKT/mTOR signaling pathway in atherosclerosis model mice

Wuguang Ji, Jing Sun, Zonghua Hu, Bo Sun

Article Number: 414 Published online on: 27 April 2022
Article Open Access

mTORC1 is a key regulator that mediates OGD‑ and TGFβ1‑induced myofibroblast transformation and chondroitin‑4‑sulfate expression in cardiac fibroblasts

Chao Li, Zheng Zhang, Yu Peng, Yanying Zhang, Wanrong Kang, Yingdong Li, Yang Hai

Article Number: 413 Published online on: 27 April 2022
Article Open Access

PAX2 induces vascular‑like structures in normal ovarian cells and ovarian cancer

Kholoud Alwosaibai, Ensaf M. Al‑Hujaily, Salmah Alamri, Salim Ghandorah, Kenneth Garson, Barbara C. Vanderhyden

Article Number: 412 Published online on: 27 April 2022
Article Open Access

Exploring reflectance confocal microscopy as a non‑invasive diagnostic tool for genital lichen sclerosus

Despoina Kantere, Noora Neittaanmäki, Kristina Maltese, Ann-Marie Wennberg Larkö, Petra Tunbäck

Article Number: 410 Published online on: 26 April 2022
Case Report Open Access

Durable response after the discontinuation of pembrolizumab treatment due to an adverse event in a patient with advanced endometrial cancer: A case report

Shuntaro Umihira, Takahiro Koyanagi, Kohei Tamura, Yoshifumi Takahashi, Takahiro Yoshiba, Suzuyo Takahashi, Akiyo Taneichi, Yasushi Saga, Yuji Takei, Hiroyuki Fujiwara

Article Number: 409 Published online on: 26 April 2022
Article

Expression and clinical significance of lncRNA BC041954 in ovarian cancer

Yan-Ming Lu, Ya-Ru Guo, Meng-Ya Zhou, Yue Wang

Article Number: 408 Published online on: 26 April 2022
Article Open Access

YY1 affects the levels and function of fibulin‑5 in ox‑LDL‑treated vascular smooth muscle cells

Leijing Wang, Cuiyan Li, Chunli Feng, Yuanbo Zang

Article Number: 407 Published online on: 21 April 2022
Article Open Access

Protective effect of sacubitril/valsartan in patients with acute myocardial infarction: A meta‑analysis

Shanshan Liu, Bi Yin, Bo Wu, Zhixing Fan

Article Number: 406 Published online on: 21 April 2022
Case Report Open Access

Middle cranial fossa trigeminal schwannoma resection through endoscopic transnasal maxillary sinus approach: A case report and literature review

Chao Xu, Pan Wang, Jun-Wei Wang, Wu-Jun Feng, Nan Wu

Article Number: 405 Published online on: 21 April 2022
Article Open Access

Circulating microRNAs in patients with aneurysmal dilatation of coronary arteries

Sylwia Iwańczyk, Tomasz Lehmann, Artur Cieślewicz, Artur Radziemski, Katarzyna Malesza, Michał Wrotyński, Paweł P. Jagodziński, Marek Grygier, Maciej Lesiak, Aleksander Araszkiewicz

Article Number: 404 Published online on: 21 April 2022
Article Open Access

Circulating miR‑15b, Annexin A1, procalcitonin and interleukin‑6 levels differentiate children with metabolically unhealthy obesity from those with metabolically healthy obesity: A case‑control study

Khalid M. Mohany, Osamah Al Rugaie, Osama Al‑Wutayd, Mansour Alsharidah, Abdullah Al‑Nafeesah

Article Number: 403 Published online on: 21 April 2022
Article Open Access

Histopathological evaluation of cutaneous malignant melanoma: A retrospective study

Daniela-Elena Gheoca Mutu, Adelaida Avino, Andra-Elena Balcangiu‑Stroescu, Mihai Mehedințu, Daniela Gabriela Bălan, Lăcrămioara Aurelia Brîndușe, Ana-Maria Popescu, Dorin Ionescu, Bogdan-Mihai Cristea, Luminiţa Florentina Tomescu, Cristian-Radu Jecan, Laura Răducu

Article Number: 402 Published online on: 20 April 2022
Article Open Access

Bisdemethoxycurcumin attenuates OVA‑induced food allergy by inhibiting the MAPK and NF‑κB signaling pathways

Yanjie Wang, Ping Zhang, Jingyu Zhang, Tie Hong

Article Number: 401 Published online on: 20 April 2022
Correction Open Access

[Corrigendum] Long non‑coding RNA HOTAIRM1‑1 silencing in cartilage tissue induces osteoarthritis through microRNA‑125b

Wen-Bin Liu, Qi-Jin Feng, Gui-Shi Li, Peng Shen, Ya-Nan Li, Fu-Jiang Zhang

Article Number: 400 Published online on: 19 April 2022
Article Open Access

Infection and reinfection with SARS‑CoV‑2 in cancer patients: A cohort study

Cornelia Nitipir, Andreea Ioana Parosanu, Mihaela Olaru, Ana Maria Popa, Cristina Pirlog, Cristian Iaciu, Radu Vrabie, Miruna Ioana Stanciu, Anca Oprescu‑Macovei, Dragos Bumbacea, Carolina Negrei, Cristina Orlov‑Slavu

Article Number: 399 Published online on: 15 April 2022
Article

Novel anti‑hepatitis B virus‑active catechin and epicatechin from Rhus tripartita

Mohammad K. Parvez, Mohammed S. Al‑Dosari, Mazin A. S. Abdelwahid, Ali S. Alqahtani, Abdullah R. Alanzi

Article Number: 398 Published online on: 15 April 2022
Article Open Access

Role of chemokines in early pregnancy loss

Sefi̇k Gokce, Di̇lsad Herki̇loglu, Ozge Cevi̇k, Volkan Turan

Article Number: 397 Published online on: 14 April 2022
Article Open Access

Activation of A2B adenosine receptor protects against demyelination in a mouse model of schizophrenia

Quanrui Ma, Dan Wang, Yunhong Li, Hao Yang, Yilu Li, Junyan Wang, Jinxia Li, Jinping Sun, Juan Liu

Article Number: 396 Published online on: 14 April 2022
Article Open Access

Thymoquinone modulates the expression of sepsis‑related microRNAs in a CLP model

Khalid M. Alkharfy, Ajaz Ahmad, Basit L. Jan, Mohammad Raish, Muneeb U. Rehman

Article Number: 395 Published online on: 14 April 2022
Case Report Open Access

Buschke‑Löwenstein tumors: A series of 7 case reports

Daniel Boda, Ana Cutoiu, Dalia Bratu, Nona Bejinariu, Rodica Crutescu

Article Number: 393 Published online on: 13 April 2022
Article

Overexpression of long non‑coding RNA NEAT1 enhances cell viability and inhibits apoptosis in recurrent spontaneous abortion by targeting the miR‑125b/BCL‑2 axis

Xiaodan Liu, Li Su, Bingnv Xu, Jing Lei, Hongjie Zhang

Article Number: 392 Published online on: 13 April 2022
Article Open Access

Clinical significance of early IgA anti‑SARS‑CoV‑2 antibody detection in patients from a Romanian referral COVID‑19 hospital

Andrei Vâţă, Adriana Anita, Carmen Doina Manciuc, Gheorghe Savuta, Catalina Mihaela Luca, Florin Manuel Roșu, Ioana Florina Mihai, Dragos Anita

Article Number: 391 Published online on: 12 April 2022
Article Open Access

Lactococcus lactis‑fermented spinach juice suppresses LPS‑induced expression of adhesion molecules and inflammatory cytokines through the NF‑κB pathway in HUVECs

Sang-Hee Lee, Ah-Ram Han, Byoung-Mok Kim, Mi Jeong Sung, Sun-Mee Hong

Article Number: 390 Published online on: 12 April 2022
Article Open Access

Immunostimulatory activity of soybean hull polysaccharide on macrophages

Mengxue Wang, Chenye Fu, Mingcong Zhang, Yuxian Zhang, Liang Cao

Article Number: 389 Published online on: 12 April 2022
Article Open Access

Application of the advanced lung cancer inflammation index for patients with coronavirus disease 2019 pneumonia: Combined risk prediction model with advanced lung cancer inflammation index, computed tomography and chest radiograph

Akitoshi Inoue, Hiroaki Takahashi, Tatsuya Ibe, Hisashi Ishii, Yuhei Kurata, Yoshikazu Ishizuka, Bolorkhand Batsaikhan, Yoichiro Hamamoto

Article Number: 388 Published online on: 12 April 2022
Case Report Open Access

Lateral sinus thrombosis in a young patient with sudden neurosensorial hearing loss and genetic thrombophilia: A case report

Zina Cuzmici‑Barabaș, Andreea Cătană, Mariela Sanda Militaru, Oana Garbea, Iuliu Vlad Cătană, Ioan Victor Pop

Article Number: 387 Published online on: 12 April 2022
Review Open Access

Risk of hepatitis B reactivation: From biologic therapies for psoriasis to immunosuppressive therapies for COVID‑19 (Review)

Liliana Baroiu, Lucreția Anghel, Alin Laurențiu Tatu, Alina Viorica Iancu, Caterina Dumitru, Ana-Cristina Leșe, Miruna Drăgănescu, Florentina Năstase, Elena Niculeț, Silvia Fotea, Aurel Nechita, Doina Carina Voinescu, Anca Ioana Stefanopol

Article Number: 385 Published online on: 12 April 2022
Retraction Open Access

[Retracted] miRNA‑429 suppresses osteogenic differentiation of human adipose‑derived mesenchymal stem cells under oxidative stress via targeting SCD‑1

Changgong Lan, Lizhen Long, Kegong Xie, Jia Liu, Landao Zhou, Shengcai Pan, Junqing Liang, Zhenyang Tu, Ziran Gao, Yujin Tang

Article Number: 384 Published online on: 11 April 2022
Review Open Access

Role of immunohistochemistry in the diagnosis and staging of cutaneous squamous‑cell carcinomas (Review)

Elena Bălășescu, Andreea-Cristina Gheorghe, Andreea Moroianu, Gabriela Turcu, Alice Brînzea, Mihaela Antohe, Anastasia Hodorogea, Lorena Manea, Mihaela Balaban, Răzvan Andrei, Ionela Hulea, Cristiana Gabriela Popp, Luciana Nichita, Mirela Daniela Cioplea, Sabina Andrada Zurac, Daniela Adriana Ion, Roxana Ioana Nedelcu

Article Number: 383 Published online on: 11 April 2022
Article Open Access

Altered small non‑coding RNA expression profiles of extracellular vesicles in the prostatic fluid of patients with chronic pelvic pain syndrome

Bin Ouyang, Dayu Han, Zexin Guo, Junhong Deng, Weilong Li, Liangliang Huang, Jianming Liu, Zhouda Cai, Jun Bian, Shaoming Huang

Article Number: 382 Published online on: 08 April 2022
Review Open Access

Immunological signature of chronic spontaneous urticaria (Review)

Carmen-Teodora Dobrican, Ioana Adriana Muntean, Irena Pintea, Carina Petricău, Diana-Mihaela Deleanu, Gabriela Adriana Filip

Article Number: 381 Published online on: 08 April 2022
Article

Targeting TNFα‑mediated cytotoxicity using thalidomide after experimental cardiac arrest in rats: An exploratory study

Abigail A. Palmer, Jason P. Stezoski, Keri Janesko‑Feldman, Patrick M. Kochanek, Tomas Drabek

Article Number: 380 Published online on: 08 April 2022
Article Open Access

Sodium to creatinine ratio in spot urine is associated with heart failure hospitalization in Japanese high‑risk patients

Tsuneaki Sadanaga, Shinichi Hirota

Article Number: 379 Published online on: 08 April 2022
Article Open Access

Potential role for pentoxifylline as an anti‑inflammatory drug for patients with acute coronary syndrome

Daniel Miron Brie, Cristian Mornos, Diduta Alina Brie, Constantin Tudor Luca, Lucian Petrescu, Madalina Boruga

Article Number: 378 Published online on: 08 April 2022
Review Open Access

Dermoscopy in the diagnosis of cutaneous lymphoma (Review)

Loredana Ungureanu, Alina Vasilovici, Simona Corina Șenilă, Ioana Cosgarea, Daniel Boda

Article Number: 377 Published online on: 07 April 2022
Article Open Access

Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest

Xiaohui Gong, Xinhui Fan, Xinxin Yin, Tonghui Xu, Jiaxin Li, Jialin Guo, Xiangkai Zhao, Shujian Wei, Qiuhuan Yuan, Jiali Wang, Xuchen Han, Yuguo Chen

Article Number: 376 Published online on: 07 April 2022
Article Open Access

Celecoxib induces adipogenic differentiation of hemangioma‑derived mesenchymal stem cells through the PPAR‑γ pathway in vitro and in vivo

Yuan Wang, Liangliang Kong, Buhao Sun, Jie Cui, Weimin Shen

Article Number: 375 Published online on: 07 April 2022
Article Open Access

Comparative proteomics identify HSP90A, STIP1 and TAGLN‑2 in serum extracellular vesicles as potential circulating biomarkers for human adenomyosis

Dayong Chen, Ling Zhou, Hai Qiao, Yiting Wang, Yao Xiao, Liaoqiong Fang, Bing Yang, Zhibiao Wang

Article Number: 374 Published online on: 07 April 2022
Article Open Access

Rutaecarpine ameliorates lipopolysaccharide‑induced BEAS‑2B cell injury through inhibition of endoplasmic reticulum stress via activation of the AMPK/SIRT1 signaling pathway

Hao Zhang, Kun Zhu, Xuefeng Zhang, Yihui Ding, Bing Zhu, Wen Meng, Fan Zhang

Article Number: 373 Published online on: 06 April 2022
Article Open Access

FOXA1 transcription activates TFF1 to reduce 6‑OHDA‑induced dopaminergic neuron damage

Tingting Liang, Ping Zhao, Xiao Zhang, Xuedan Han, Bo Hong, Lingsheng Kong, Huanxian Chang, Liyan Liu

Article Number: 372 Published online on: 05 April 2022
Article Open Access

Berberine attenuates sepsis‑induced cardiac dysfunction by upregulating the Akt/eNOS pathway in mice

Hong Zhang, Xiaofei Wu, Yanyan Tao, Guoyu Lu

Article Number: 371 Published online on: 05 April 2022
Article Open Access

Predictive performance of first trimester serum galectin‑13/PP‑13 in preeclampsia screening: A systematic review and meta‑analysis

Ingrid-Andrada Vasilache, Alexandru Carauleanu, Demetra Socolov, Roxana Matasariu, Ioana Pavaleanu, Dragos Nemescu

Article Number: 370 Published online on: 05 April 2022
Article Open Access

Spironolactone alleviates myocardial fibrosis via inhibition of Ets‑1 in mice with experimental autoimmune myocarditis

Wen-Ke Wang, Ben Wang, Xue-Hu Cao, Yu-Sheng Liu

Article Number: 369 Published online on: 05 April 2022
Article Open Access

Identification of key candidate genes and biological pathways in the synovial tissue of patients with rheumatoid arthritis

Feng Yu, Guanghui Hu, Lei Li, Bo Yu, Rui Liu

Article Number: 368 Published online on: 04 April 2022
Journal Cover

June-2022
Volume 23 Issue 6

Print ISSN: 1792-0981
Online ISSN: 1792-1015

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