Dysregulated expression of miR‑367 in disease development and its prospects as a therapeutic target and diagnostic biomarker (Review)

  • Authors:
    • Shaleniprieya Muniandy
    • Ling Ling Few
    • Boon Yin Khoo
    • Siti Asma' Hassan
    • Get Bee Yvonne-Τee
    • Wei Cun See Too
  • View Affiliations

  • Published online on: October 10, 2023     https://doi.org/10.3892/br.2023.1673
  • Article Number: 91
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Abstract

MicroRNA (miR)‑367 has a wide range of functions in gene regulation and as such plays a critical role in cell proliferation, differentiation and development, making it an essential molecule in various physiological processes. miR‑367 belongs to the miR‑302/367 cluster and is located in the intronic region of human chromosome 4 on the 4q25 locus. Dysregulation of miR‑367 is associated with various disease conditions, including cancer, inflammation and cardiac conditions. Moreover, miR‑367 has shown promise both as a tumor suppressor and a potential diagnostic biomarker for breast, gastric and prostate cancer. The elucidation of the essential role of miR‑367 in inflammation, development and cardiac diseases emphasizes its versatility in regulating various physiological processes beyond cancer biology. However, further research is necessary to fully understand the complex regulatory mechanisms involving miR‑367 in different physiological and pathological contexts. In conclusion, the versatility and significance of miR‑367 makes it a promising candidate for further study and in the development of new diagnostic and therapeutic strategies.
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December-2023
Volume 19 Issue 6

Print ISSN: 2049-9434
Online ISSN:2049-9442

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Spandidos Publications style
Muniandy S, Few LL, Khoo BY, Hassan SA, Yvonne-Τee GB and See Too WC: Dysregulated expression of miR‑367 in disease development and its prospects as a therapeutic target and diagnostic biomarker (Review). Biomed Rep 19: 91, 2023
APA
Muniandy, S., Few, L.L., Khoo, B.Y., Hassan, S.A., Yvonne-Τee, G.B., & See Too, W.C. (2023). Dysregulated expression of miR‑367 in disease development and its prospects as a therapeutic target and diagnostic biomarker (Review). Biomedical Reports, 19, 91. https://doi.org/10.3892/br.2023.1673
MLA
Muniandy, S., Few, L. L., Khoo, B. Y., Hassan, S. A., Yvonne-Τee, G. B., See Too, W. C."Dysregulated expression of miR‑367 in disease development and its prospects as a therapeutic target and diagnostic biomarker (Review)". Biomedical Reports 19.6 (2023): 91.
Chicago
Muniandy, S., Few, L. L., Khoo, B. Y., Hassan, S. A., Yvonne-Τee, G. B., See Too, W. C."Dysregulated expression of miR‑367 in disease development and its prospects as a therapeutic target and diagnostic biomarker (Review)". Biomedical Reports 19, no. 6 (2023): 91. https://doi.org/10.3892/br.2023.1673