Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Biomedical Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9434 Online ISSN: 2049-9442
Journal Cover
August-2024 Volume 21 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2024 Volume 21 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report Open Access

Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report

  • Authors:
    • Karla Kovačević
    • Biljana Jelić Puškarić
    • Dragica Obad Kovačević
  • View Affiliations / Copyright

    Affiliations: Department of Diabetes and Endocrinology, Vuk Vrhovac University Clinic for Diabetes, Endocrinology and Metabolic Diseases, Merkur University Hospital, 10 000 Zagreb, Croatia, Department of Pathology and Cytology, Merkur University Hospital, 10 000 Zagreb, Croatia, Department of Diagnostic and Interventional Radiology, Merkur University Hospital, 10 000 Zagreb, Croatia
    Copyright: © Kovačević et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 114
    |
    Published online on: June 12, 2024
       https://doi.org/10.3892/br.2024.1801
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

During a routine ultrasound examination of the abdomen, a 60‑year‑old male patient was diagnosed with mass in the tail of the pancreas. However, computed tomography (CT) suggested that the lesion was an intrapancreatic accessory spleen (IPAS). IPAS is a congenital anomaly, which usually does not present with symptoms. IPAS occurs during embryologic splenic development when a portion of the splenic tissue fails to fuse with the main body of the spleen. IPAS does not require treatment, except when it is combined with idiopathic thrombocytopenic purpura. In the present case, the diagnosis of IPAS was confirmed using magnetic resonance imaging (MRI). On CT and MRI, the IPAS had a density and intensity comparable with that of the spleen in all plain and contrast‑enhanced phases. Due to comorbidities, the patient refused further evaluation or surgery. The lesion was periodically monitored using CT every 1‑2 years. Since the tumour was stable during the 7‑year follow‑up, it was concluded that it was an IPAS. In patients that cannot undergo surgery, a characteristic location (near the spleen) and imaging features (such as a ‘zebra‑patterned’ enhancement in the arterial phase on CT and high signal intensity on diffusion‑weighted imaging sequences on MRI, which is comparative to that of the normal spleen) may allow for a diagnose of IPAS with a high level of certainty. Being aware of this condition could aid a correct diagnosis of IPAS and prevent unnecessary surgery.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

View References

1 

Marques S, Bispo M and Noia L: Intrapancreatic accessory spleen: A diagnosis not to forget! Case Rep. Gastroenterol. 10:749–754. 2016.PubMed/NCBI View Article : Google Scholar

2 

Kim SH, Lee JM, Han JK, Lee JY, Kim KW, Cho KC, Cho KC and Choi BI: Intrapancreatic accessory spleen: Findings on MR imaging, CT, US and scintigraphy, and the pathologic analysis. Korean J Radiol. 9:162–174. 2008.PubMed/NCBI View Article : Google Scholar

3 

Hwang HS, Lee SS, Kim SC, Seo DW and Kim J: Intrapancreatic accessory spleen: Clinicopathologic analysis of 12 cases. Pancreas. 40:956–965. 2011.PubMed/NCBI View Article : Google Scholar

4 

Osher E, Scapa E, Klausner J, Greenman Y, Tordjman K, Melhem A, Nachmany I, Sofer Y, Geva R, Blachar A, et al: Pancreatic incidentaloma: Differentiating nonfunctioning pancreatic neuroendocrine tumours from intrapancreatic accessory spleen. Endocr Pract. 22:773–779. 2016.PubMed/NCBI View Article : Google Scholar

5 

Massani M, Maccatrozzo P, Morana G, Fabris L, Ruffolo C, Bonariol L, Pauletti B and Bassi N: Diagnostic difficulties and therapeutic choices in intrapancreatic accessory spleen: Case reports. Open Access Surg. 9:15–20. 2016.

6 

Spencer LA, Spizarny DL and Williams TR: Imaging features of intrapancreatic accessory spleen. Br J Radiol. 83:668–673. 2010.PubMed/NCBI View Article : Google Scholar

7 

Santo E and Bar-Yishay I: Pancreatic solid incidentalomas. Endosc Ultrasound. 6 (Suppl 3):S99–S103. 2017.PubMed/NCBI View Article : Google Scholar

8 

Rahbar H, Bhargava P, Vaidya S and Medverd JR: Intrapancreatic accessory spleen. Radiol Case Rep. 5(386)2015.PubMed/NCBI View Article : Google Scholar

9 

Loureiro AL, Ferreira AO, Palmeiro M and Penedo JP: Intrapancreatic accessory spleen: A misleading diagnosis. BMJ Case Rep. 2013(bcr2012008471)2013.PubMed/NCBI View Article : Google Scholar

10 

Guo W, Han W, Liu J, Jin L, Li JS, Zhang ZT and Wang Y: Intrapancreatic accessory spleen: A case report and review of the literature. World J Gastroenterol. 15:1141–1143. 2009.PubMed/NCBI View Article : Google Scholar

11 

Kykalos S, Machairas N, Molmenti EP and Sotiropoulos G: Intrapancreatic accessory spleen: Two case reports of a rare entity. Cureus. 12(e8797)2020.PubMed/NCBI View Article : Google Scholar

12 

Li BQ, Xu XQ and Guo JC: Intrapancreatic accessory spleen: A diagnostic dilemma. HPB (Oxford). 20:1004–1011. 2018.PubMed/NCBI View Article : Google Scholar

13 

Munk-Madsen MZ, Zakarian K, Sandor Oturai P, Hansen CP, Federspiel B, Fallentin E and Linno Willemoe G: Intrapancreatic accessory spleen mimicking malignant tumour: Three case reports. Acta Radiol Open. 8(2058460119859347)2019.PubMed/NCBI View Article : Google Scholar

14 

Contractor U, Henderson I and Zaitoun MD: Intrapancreatic accessory spleen: An important differential to consider before surgery. Hum Pathol Case Rep. 1:49–51. 2014.

15 

Chavan N, Desai GS, Tampi C and Wagle P: Intrapancreatic accessory spleen: An enigmatic entity. BMJ Case Rep. 12(e228510)2019.PubMed/NCBI View Article : Google Scholar

16 

Hashimoto K, Nishimura S, Ito T, Oka N and Akagi M: Limitations and usefulness of biopsy techniques for the diagnosis of metastatic bone and soft tissue tumours. Ann Med Surg (Lond). 68(102581)2021.PubMed/NCBI View Article : Google Scholar

17 

García AF and Sanjuanbenito Dehesa A: Intrapancreatic accessory spleen: A rare cause of recurrence of immune thrombocytopenic purpura. Clin Case Rep. 4:979–981. 2016.PubMed/NCBI View Article : Google Scholar

18 

Obuchi T, Takagane A, Sato K, Yonezawa H, Funato O and Kobayashi M: Single-incision laparoscopic excision of symptomatic accessory spleen in the pelvis: An initial report. J Minim Access Surg. 13:321–322. 2017.PubMed/NCBI View Article : Google Scholar

19 

Hems TE and Bellringer JF: Torsion of an accessory spleen in an elderly patient. Postgrad Med J. 66:838–839. 1990.PubMed/NCBI View Article : Google Scholar

20 

O'Riordan B, Rodendo O and Stafford A: Laparoscopic distal pancreatectomy and splenectomy for an intrapancreatic accessory spleen-a case report and review of the literature. Mesentery Peritoneum. 6(AB154)2022.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Kovačević K, Puškarić BJ and Kovačević DO: Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report. Biomed Rep 21: 114, 2024.
APA
Kovačević, K., Puškarić, B.J., & Kovačević, D.O. (2024). Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report. Biomedical Reports, 21, 114. https://doi.org/10.3892/br.2024.1801
MLA
Kovačević, K., Puškarić, B. J., Kovačević, D. O."Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report". Biomedical Reports 21.2 (2024): 114.
Chicago
Kovačević, K., Puškarić, B. J., Kovačević, D. O."Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report". Biomedical Reports 21, no. 2 (2024): 114. https://doi.org/10.3892/br.2024.1801
Copy and paste a formatted citation
x
Spandidos Publications style
Kovačević K, Puškarić BJ and Kovačević DO: Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report. Biomed Rep 21: 114, 2024.
APA
Kovačević, K., Puškarić, B.J., & Kovačević, D.O. (2024). Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report. Biomedical Reports, 21, 114. https://doi.org/10.3892/br.2024.1801
MLA
Kovačević, K., Puškarić, B. J., Kovačević, D. O."Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report". Biomedical Reports 21.2 (2024): 114.
Chicago
Kovačević, K., Puškarić, B. J., Kovačević, D. O."Imaging‑based diagnosis of intrapancreatic accessory spleen: A case report". Biomedical Reports 21, no. 2 (2024): 114. https://doi.org/10.3892/br.2024.1801
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team