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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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December-2026 Volume 32 Issue 6

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Article Open Access

Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures

  • Authors:
    • Jie Liang
    • Shuangli Lan
    • Shunjie Dang
    • Guiwen Luo
    • Yunkang Yang
  • View Affiliations / Copyright

    Affiliations: Department of Bone and Joint Surgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China, Department of Hepatobiliary Surgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China
    Copyright: © Liang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 333
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    Published online on: October 6, 2026
       https://doi.org/10.3892/etm.2026.13328
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Abstract

The present study aimed to identify risk factors for postoperative deep vein thrombosis (DVT) in patients with periarticular knee fractures. A prediction model was constructed for the early identification of high‑risk patients. Data from 319 patients at who underwent surgery at the Affiliated Hospital of Southwest Medical University (Luzhou, China) between January 2020 and December 2022 were analyzed. Based on ultrasound results, patients were divided into a DVT group (n=83) and a non‑DVT group (n=236). Logistic regression was employed to identify independent risk factors. Subsequently, a nomogram model was established, which was validated via receiver operating characteristic curves, calibration curves and decision curve analysis (DCA). The DVT rate was 26.0%. Old age (OR, 1.0228), high American Society of Anesthesiologists grade (OR, 2.2764), greater blood loss (OR, 1.0015), blood transfusion (OR, 2.7917) and high D‑dimer levels (OR, 1.0251) were identified as independent risk factors (P<0.05), while living in cities, high hemoglobin, high prealbumin, high Barthel index and high Braden scores served as protective factors (P<0.05). The model yielded an area under the curve value of 0.837. Additionally, the calibration curve showed high accuracy, and DCA validated the favorable clinical applicability of this predictive model. In conclusion, the model performs well in helping doctors to identify high‑risk patients and optimize individualized therapeutic strategies. 

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Copy and paste a formatted citation
Spandidos Publications style
Liang J, Lan S, Dang S, Luo G and Yang Y: Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures. Exp Ther Med 32: 333, 2026.
APA
Liang, J., Lan, S., Dang, S., Luo, G., & Yang, Y. (2026). Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures. Experimental and Therapeutic Medicine, 32, 333. https://doi.org/10.3892/etm.2026.13328
MLA
Liang, J., Lan, S., Dang, S., Luo, G., Yang, Y."Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures". Experimental and Therapeutic Medicine 32.6 (2026): 333.
Chicago
Liang, J., Lan, S., Dang, S., Luo, G., Yang, Y."Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures". Experimental and Therapeutic Medicine 32, no. 6 (2026): 333. https://doi.org/10.3892/etm.2026.13328
Copy and paste a formatted citation
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Spandidos Publications style
Liang J, Lan S, Dang S, Luo G and Yang Y: Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures. Exp Ther Med 32: 333, 2026.
APA
Liang, J., Lan, S., Dang, S., Luo, G., & Yang, Y. (2026). Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures. Experimental and Therapeutic Medicine, 32, 333. https://doi.org/10.3892/etm.2026.13328
MLA
Liang, J., Lan, S., Dang, S., Luo, G., Yang, Y."Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures". Experimental and Therapeutic Medicine 32.6 (2026): 333.
Chicago
Liang, J., Lan, S., Dang, S., Luo, G., Yang, Y."Analysis of risk factors and construction of a prediction model for postoperative deep vein thrombosis in patients with periarticular knee fractures". Experimental and Therapeutic Medicine 32, no. 6 (2026): 333. https://doi.org/10.3892/etm.2026.13328
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