[Corrigendum] High expression of the secreted protein dickkopf homolog 4: Roles in invasion and metastasis of renal cell carcinoma and its association with Von Hippel-Lindau gene

• Authors:
  • Wei Zhai
  • Guang-Hui Hu
  • Jun-Hua Zheng
  • Bo Peng
  • Min Liu
  • Jian-Hua Huang
  • Guang-Chun Wang
  • Xu-Dong Yao
  • Yun-Fei Xu

• View Affiliations

  
  Affiliations: Department of Urology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. China
• Published online on: April 18, 2023     https://doi.org/10.3892/ijmm.2023.5250
• Article Number: 47

• Copyright : © Zhai et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

Article

Int J Mol Med 33: [Related article:] 1319-1326, 2014; DOI: 10.3892/ijmm.2014.1673

Subsequently to the publication of the above paper, an interested reader drew to the authors' attention that the β-actin bands data shown to portray the control experiments in the western blots in Fig. 3C and 4F were apparently identical. The authors have re-examined their data, and realize that the control bands in Fig. 3C had inadvertently been selected incorrectly.

Figure 3 In vivo experiments with empty and with dickkopf homolog 4 (DKK4)-transfected renal cancer cells. (A) Determination of tumor volume in nude mice implanted with 786-O and A-498 cells transfected with empty vector (control) or with cells transfected with pCDH-DKK4 plasmid. (B) Detection of DKK4 mRNA expression levels in mice implanted with DKK4-overexpressing cells or empty vector-transfected control cells. (C) Detection of DKK4 protein expression levels in mice implanted with DKK4-overexpressing cells or empty vector-transfected control cells. **p<0.01 compared with controls (empty vector transfectants).

The revised version of Fig. 3, containing the correct β-actin bands in Fig. 3C, is shown below. Note that this error did not affect the major conclusions reported in the paper. All the authors agree with the publication of this corrigendum, and thank the Editor of International Journal of Molecular Medicine for allowing them the opportunity to publish this. The authors regret this mistake went unnoticed during the compilation of the figure in question, and apologize to the readership for any confusion that this may have caused.

Figure 3 In vivo experiments with empty and with dickkopf homolog 4 (DKK4)-transfected renal cancer cells. (A) Determination of tumor volume in nude mice implanted with 786-O and A-498 cells transfected with empty vector (control) or with cells transfected with pCDH-DKK4 plasmid. (B) Detection of DKK4 mRNA expression levels in mice implanted with DKK4-overexpressing cells or empty vector-transfected control cells. (C) Detection of DKK4 protein expression levels in mice implanted with DKK4-overexpressing cells or empty vector-transfected control cells. **p<0.01 compared with controls (empty vector transfectants).