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Sesaminol from sesame seed induces apoptosis in human lymphoid leukemia Molt 4B cells

  • Authors:
    • Y. Miyahara
    • H. Hibasami
    • H. Katsuzaki
    • K. Imai
    • T. Osawa
    • K. Ina
    • T. Komiya

  • View Affiliations

  • Published online on: May 1, 2001     https://doi.org/10.3892/ijmm.7.5.485
  • Pages: 485-488
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

The exposure of human lymphoid leukemia Molt 4B cells to sesaminol, a component of sesame oil led to both growth inhibition and the induction of apoptosis. Morphological change showing apoptotic bodies was observed in the cells treated with sesaminol. The fragmentation of DNA by sesaminol to oligonucleosomal-sized fragments that are characteristics of apoptosis was observed to be concentration- and time-dependent. These findings suggest that growth inhibition of Molt 4B cells by sesaminol results from the induction of apoptosis in the cells.

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May 2001
Volume 7 Issue 5

Print ISSN: 1107-3756
Online ISSN:1791-244X

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  • Journal Metrics
  • Impact Factor: 5.7
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 12.3
  • CiteScore Rank: Q1: #28/347 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 1.022
  • SCImago Journal Rank (SJR): 1.167
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Spandidos Publications style
Miyahara Y, Hibasami H, Katsuzaki H, Imai K, Osawa T, Ina K and Komiya T: Sesaminol from sesame seed induces apoptosis in human lymphoid leukemia Molt 4B cells. Int J Mol Med 7: 485-488, 2001.
APA
Miyahara, Y., Hibasami, H., Katsuzaki, H., Imai, K., Osawa, T., Ina, K., & Komiya, T. (2001). Sesaminol from sesame seed induces apoptosis in human lymphoid leukemia Molt 4B cells. International Journal of Molecular Medicine, 7, 485-488. https://doi.org/10.3892/ijmm.7.5.485
MLA
Miyahara, Y., Hibasami, H., Katsuzaki, H., Imai, K., Osawa, T., Ina, K., Komiya, T."Sesaminol from sesame seed induces apoptosis in human lymphoid leukemia Molt 4B cells". International Journal of Molecular Medicine 7.5 (2001): 485-488.
Chicago
Miyahara, Y., Hibasami, H., Katsuzaki, H., Imai, K., Osawa, T., Ina, K., Komiya, T."Sesaminol from sesame seed induces apoptosis in human lymphoid leukemia Molt 4B cells". International Journal of Molecular Medicine 7, no. 5 (2001): 485-488. https://doi.org/10.3892/ijmm.7.5.485