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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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July 2001 Volume 8 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 2001 Volume 8 Issue 1

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Article

Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique

  • Authors:
    • Masao Suzuki
    • Chang-Qing Piao
    • Yong-Liang Zhao
    • Tom K. Hei

  • View Affiliations / Copyright

    Affiliations: International Space Radiation Laboratory, National Institute of Radiological Sciences, Inage-ku, Chiba 263-8555, Japan
  • Pages: 43-47
    |
    Published online on: July 1, 2001
       https://doi.org/10.3892/ijmm.8.1.43
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Abstract

We examined karyotypic changes of tumorigenic human bronchial epithelial cell lines transformed by asbestos fibers. Using Calyculin A mediated premature chromosome condensation (PCC) assay and Giemsa-trypsin banding, we showed that the common changes of all tumorigenic cell lines were the loss of one or two copies of chromosome 5, the monosomy of chromosome 19 and the increased trisomy of chromosome 8. The results indicate that the karyotypic change of chromosome 5, 8 and 19 could play an important role in asbestos-induced tumorigenic conversion of human bronchial epithelial cells from an immortalized to tumorigenic state.

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Copy and paste a formatted citation
Spandidos Publications style
Suzuki M, Piao C, Zhao Y and Hei TK: Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique. Int J Mol Med 8: 43-47, 2001.
APA
Suzuki, M., Piao, C., Zhao, Y., & Hei, T.K. (2001). Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique. International Journal of Molecular Medicine, 8, 43-47. https://doi.org/10.3892/ijmm.8.1.43
MLA
Suzuki, M., Piao, C., Zhao, Y., Hei, T. K."Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique". International Journal of Molecular Medicine 8.1 (2001): 43-47.
Chicago
Suzuki, M., Piao, C., Zhao, Y., Hei, T. K."Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique". International Journal of Molecular Medicine 8, no. 1 (2001): 43-47. https://doi.org/10.3892/ijmm.8.1.43
Copy and paste a formatted citation
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Spandidos Publications style
Suzuki M, Piao C, Zhao Y and Hei TK: Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique. Int J Mol Med 8: 43-47, 2001.
APA
Suzuki, M., Piao, C., Zhao, Y., & Hei, T.K. (2001). Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique. International Journal of Molecular Medicine, 8, 43-47. https://doi.org/10.3892/ijmm.8.1.43
MLA
Suzuki, M., Piao, C., Zhao, Y., Hei, T. K."Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique". International Journal of Molecular Medicine 8.1 (2001): 43-47.
Chicago
Suzuki, M., Piao, C., Zhao, Y., Hei, T. K."Karyotype analysis of tumorigenic human bronchial epithelial cells transformed by chrysolite asbestos using chemically induced premature chromosome condensation technique". International Journal of Molecular Medicine 8, no. 1 (2001): 43-47. https://doi.org/10.3892/ijmm.8.1.43
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