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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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October 2008 Volume 22 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Article

Visible and near-infrared spectral changes in plasma of psychiatric patients

  • Authors:
    • Yukiko Hakariya Kato
    • Hidenori Matsunaga
    • Akikazu Sakudo
    • Kazuyoshi Ikuta

  • View Affiliations / Copyright

    Affiliations: Department of Virology, Center for Infectious Disease Control, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan
  • Pages: 513-519
    |
    Published online on: October 1, 2008
       https://doi.org/10.3892/ijmm_00000050
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Abstract

In the present study, the possible difference in visible and near-infrared (Vis-NIR) spectra of plasma in psychiatric patients compared to healthy control subjects was investigated. Mean Vis-NIR spectra of 60 psychiatric patients showed several specific peaks in the 630- to 930-nm region. Principal component analysis (PCA) and soft independent modeling of class analogy (SIMCA) were applied to manifest the spectral characteristics of each group. The PCA and SIMCA models demonstrated successful discrimination of the two groups using a score plot of the third versus fourth principal component and a Coomans plot, respectively. The PCA loadings were generally consistent with the discriminating power of the SIMCA model, indicating a specific pattern of Vis-NIR spectra in the plasma of psychiatric patients. The specific pattern possibly indicates altered superoxide, amine, and primary and secondary amides in plasma and may provide a possible indicator for the diagnosis of heterogeneous psychiatric disorders. This is the first step toward a clinical tool which has the potential to be applied in the diagnosis of psychiatric disease. Yet, there remain obstacles to its practical usage.

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Copy and paste a formatted citation
Spandidos Publications style
Kato YH, Matsunaga H, Sakudo A and Ikuta K: Visible and near-infrared spectral changes in plasma of psychiatric patients. Int J Mol Med 22: 513-519, 2008.
APA
Kato, Y.H., Matsunaga, H., Sakudo, A., & Ikuta, K. (2008). Visible and near-infrared spectral changes in plasma of psychiatric patients. International Journal of Molecular Medicine, 22, 513-519. https://doi.org/10.3892/ijmm_00000050
MLA
Kato, Y. H., Matsunaga, H., Sakudo, A., Ikuta, K."Visible and near-infrared spectral changes in plasma of psychiatric patients". International Journal of Molecular Medicine 22.4 (2008): 513-519.
Chicago
Kato, Y. H., Matsunaga, H., Sakudo, A., Ikuta, K."Visible and near-infrared spectral changes in plasma of psychiatric patients". International Journal of Molecular Medicine 22, no. 4 (2008): 513-519. https://doi.org/10.3892/ijmm_00000050
Copy and paste a formatted citation
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Spandidos Publications style
Kato YH, Matsunaga H, Sakudo A and Ikuta K: Visible and near-infrared spectral changes in plasma of psychiatric patients. Int J Mol Med 22: 513-519, 2008.
APA
Kato, Y.H., Matsunaga, H., Sakudo, A., & Ikuta, K. (2008). Visible and near-infrared spectral changes in plasma of psychiatric patients. International Journal of Molecular Medicine, 22, 513-519. https://doi.org/10.3892/ijmm_00000050
MLA
Kato, Y. H., Matsunaga, H., Sakudo, A., Ikuta, K."Visible and near-infrared spectral changes in plasma of psychiatric patients". International Journal of Molecular Medicine 22.4 (2008): 513-519.
Chicago
Kato, Y. H., Matsunaga, H., Sakudo, A., Ikuta, K."Visible and near-infrared spectral changes in plasma of psychiatric patients". International Journal of Molecular Medicine 22, no. 4 (2008): 513-519. https://doi.org/10.3892/ijmm_00000050
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