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DIFFERENCES IN THE TUMOR DNA ANALYSIS OF A HEPATOCELLULAR-CARCINOMA AND A SYNCHRONOUS FIBROLAMELLAR VARIANT

  • Authors:
    • SF DING
    • K WONG
    • B DAVIDSON
    • J DOOLEY
    • AP DHILLON
    • CB WOOD
    • NA HABIB

  • View Affiliations

  • Published online on: July 1, 1992     https://doi.org/10.3892/ijo.1.2.191
  • Pages: 191-193
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Abstract

A 60 year old man had two tumours resected from his liver which were shown histologically to be a well differentiated hepatocellular carcinoma and the fibrolamellar variant. Both are considered clinically distinct and of different pathogenesis and have not been previously reported occurring synchronously. DNA analysis revealed allele loss on chromosome 12 in the hepatocellular carcinoma which was not found in the fibrolamellar variant. This finding may suggest that hepatocellular carcinoma and fibrolamellar variant may have different molecular-genetic mechanisms for the development, in addition to their clinico-pathological difference.

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July 1992
Volume 1 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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  • Impact Factor: 5.2
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  • CiteScore: 11.4
  • CiteScore Rank: Q1: #40/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 1.125
  • SCImago Journal Rank (SJR): 1.105
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Spandidos Publications style
DING S, WONG K, DAVIDSON B, DOOLEY J, DHILLON A, WOOD C and HABIB N: DIFFERENCES IN THE TUMOR DNA ANALYSIS OF A HEPATOCELLULAR-CARCINOMA AND A SYNCHRONOUS FIBROLAMELLAR VARIANT. Int J Oncol 1: 191-193, 1992
APA
DING, S., WONG, K., DAVIDSON, B., DOOLEY, J., DHILLON, A., WOOD, C., & HABIB, N. (1992). DIFFERENCES IN THE TUMOR DNA ANALYSIS OF A HEPATOCELLULAR-CARCINOMA AND A SYNCHRONOUS FIBROLAMELLAR VARIANT. International Journal of Oncology, 1, 191-193. https://doi.org/10.3892/ijo.1.2.191
MLA
DING, S., WONG, K., DAVIDSON, B., DOOLEY, J., DHILLON, A., WOOD, C., HABIB, N."DIFFERENCES IN THE TUMOR DNA ANALYSIS OF A HEPATOCELLULAR-CARCINOMA AND A SYNCHRONOUS FIBROLAMELLAR VARIANT". International Journal of Oncology 1.2 (1992): 191-193.
Chicago
DING, S., WONG, K., DAVIDSON, B., DOOLEY, J., DHILLON, A., WOOD, C., HABIB, N."DIFFERENCES IN THE TUMOR DNA ANALYSIS OF A HEPATOCELLULAR-CARCINOMA AND A SYNCHRONOUS FIBROLAMELLAR VARIANT". International Journal of Oncology 1, no. 2 (1992): 191-193. https://doi.org/10.3892/ijo.1.2.191