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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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February 1997 Volume 10 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February 1997 Volume 10 Issue 2

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Article

Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor

  • Authors:
    • H Okina
    • A Kataoka
    • T Sugiyama
    • T Nishida
    • M Yakushiji

  • View Affiliations / Copyright

    Affiliations: KURUME UNIV,SCH MED,DEPT OBSTET & GYNECOL,KURUME,FUKUOKA 830,JAPAN.
  • Pages: 311-316
    |
    Published online on: February 1, 1997
       https://doi.org/10.3892/ijo.10.2.311
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Abstract

The establishment and characterization of a new human endometrioid adenocarcinoma cell line (KOC-8e) derived from the malignant ascites is described. The original tumor at the initial operation showed positive in TPA, and SLX immunohistochemically. By contrast, recurred tumor showed positive for CA125, TPA, SLX, MUC-1, and p53. In addition, the heterotransplanted tumor showed positive for CA125, TPA, SLX, MUG-1, and p53. The DNA index was similar in the primary, recurred, and nude mouse tumor ranging between 1.93 and 2.05. The tumor growths were suppressed dose dependently by CDDP and CPT-11. CA125 showed useful as a tumor marker of this tumor, however, the nude mice had detectable tumor without elevation of CA125 after low dose application of CDDP and CPT-11. Thus, clinical determination of chemotherapeutic effect and residual tumor cannot be made only by CA125. KOC-8e cells could be useful to study histological analysis and chemosensitivity.

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Copy and paste a formatted citation
Spandidos Publications style
Okina H, Kataoka A, Sugiyama T, Nishida T and Yakushiji M: Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor. Int J Oncol 10: 311-316, 1997.
APA
Okina, H., Kataoka, A., Sugiyama, T., Nishida, T., & Yakushiji, M. (1997). Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor. International Journal of Oncology, 10, 311-316. https://doi.org/10.3892/ijo.10.2.311
MLA
Okina, H., Kataoka, A., Sugiyama, T., Nishida, T., Yakushiji, M."Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor". International Journal of Oncology 10.2 (1997): 311-316.
Chicago
Okina, H., Kataoka, A., Sugiyama, T., Nishida, T., Yakushiji, M."Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor". International Journal of Oncology 10, no. 2 (1997): 311-316. https://doi.org/10.3892/ijo.10.2.311
Copy and paste a formatted citation
x
Spandidos Publications style
Okina H, Kataoka A, Sugiyama T, Nishida T and Yakushiji M: Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor. Int J Oncol 10: 311-316, 1997.
APA
Okina, H., Kataoka, A., Sugiyama, T., Nishida, T., & Yakushiji, M. (1997). Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor. International Journal of Oncology, 10, 311-316. https://doi.org/10.3892/ijo.10.2.311
MLA
Okina, H., Kataoka, A., Sugiyama, T., Nishida, T., Yakushiji, M."Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor". International Journal of Oncology 10.2 (1997): 311-316.
Chicago
Okina, H., Kataoka, A., Sugiyama, T., Nishida, T., Yakushiji, M."Establishment and characterization of ovarian endometrioid adenocarcinoma cell line in nude mice and analyses of the immunohistochemical property among the original, recurred, and heterotransplanted tumor". International Journal of Oncology 10, no. 2 (1997): 311-316. https://doi.org/10.3892/ijo.10.2.311
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