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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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March 1997 Volume 10 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March 1997 Volume 10 Issue 3

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Article

Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer

  • Authors:
    • B Gomendio
    • J Silva
    • M Provencio
    • J Garcia
    • E GarciaPatino
    • C GarciaAndrade
    • L Carretero
    • P Espana
    • F Bonilla

  • View Affiliations / Copyright

    Affiliations: CLIN TRABAJO,MOL GENET UNIT,MADRID 28003,SPAIN. CLIN PUERTA DE HIERRO,DEPT MED ONCOL,MADRID 28035,SPAIN. HOSP SANTA CRISTINA,DEPT PATHOL,E-28009 MADRID,SPAIN. HOSP GEN GREGORIO MARANON,DEPT PATHOL,MADRID 28009,SPAIN.
  • Pages: 659-663
    |
    Published online on: March 1, 1997
       https://doi.org/10.3892/ijo.10.3.659
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Abstract

Sporadic breast cancer is the commonest form of this malignancy. Genetic changes are frequent events in breast cancer. We investigated the implication of LOH in the 17q21 region as a prognostic factor in this disease. Fifty-three patients were studied and 14 clinico-pathological parameters were evaluated for comparison between the patients with LOH and patients without LOH. A LOH rate of 21% was found and, upon comparison of the two subgroups, a significantly lower rate of recurrence after adjuvant chemotherapy in patients with LOH was observed. This suggests that LOH occurring in this region in breast cancer could help to design new adjuvant treatment strategies.

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Copy and paste a formatted citation
Spandidos Publications style
Gomendio B, Silva J, Provencio M, Garcia J, GarciaPatino E, GarciaAndrade C, Carretero L, Espana P and Bonilla F: Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer. Int J Oncol 10: 659-663, 1997.
APA
Gomendio, B., Silva, J., Provencio, M., Garcia, J., GarciaPatino, E., GarciaAndrade, C. ... Bonilla, F. (1997). Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer. International Journal of Oncology, 10, 659-663. https://doi.org/10.3892/ijo.10.3.659
MLA
Gomendio, B., Silva, J., Provencio, M., Garcia, J., GarciaPatino, E., GarciaAndrade, C., Carretero, L., Espana, P., Bonilla, F."Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer". International Journal of Oncology 10.3 (1997): 659-663.
Chicago
Gomendio, B., Silva, J., Provencio, M., Garcia, J., GarciaPatino, E., GarciaAndrade, C., Carretero, L., Espana, P., Bonilla, F."Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer". International Journal of Oncology 10, no. 3 (1997): 659-663. https://doi.org/10.3892/ijo.10.3.659
Copy and paste a formatted citation
x
Spandidos Publications style
Gomendio B, Silva J, Provencio M, Garcia J, GarciaPatino E, GarciaAndrade C, Carretero L, Espana P and Bonilla F: Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer. Int J Oncol 10: 659-663, 1997.
APA
Gomendio, B., Silva, J., Provencio, M., Garcia, J., GarciaPatino, E., GarciaAndrade, C. ... Bonilla, F. (1997). Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer. International Journal of Oncology, 10, 659-663. https://doi.org/10.3892/ijo.10.3.659
MLA
Gomendio, B., Silva, J., Provencio, M., Garcia, J., GarciaPatino, E., GarciaAndrade, C., Carretero, L., Espana, P., Bonilla, F."Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer". International Journal of Oncology 10.3 (1997): 659-663.
Chicago
Gomendio, B., Silva, J., Provencio, M., Garcia, J., GarciaPatino, E., GarciaAndrade, C., Carretero, L., Espana, P., Bonilla, F."Prognostic implications of loss of heterozygosity in the 17q21 region in breast cancer". International Journal of Oncology 10, no. 3 (1997): 659-663. https://doi.org/10.3892/ijo.10.3.659
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