Association of tumor induced vascularization with clinicopathological parameters in cervical neoplasm

  • Authors:
    • A Dellas
    • H Moch
    • E Schultheiss
    • G Feichter
    • A Almendral
    • F Gudat
    • J Torhorst
  • View Affiliations

  • Published online on: July 1, 1997     https://doi.org/10.3892/ijo.11.1.105
  • Pages: 105-109
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Abstract

Angiogenic properties have been shown in preinvasive cervical lesions. Our goal was to determine the angiogenesis in cervical intraepithelial neoplasms (CIN), the relationship between microvessel counts, histopathological parameters and the clinical outcome in invasive cervical carcinoma. Comparison of microvessel counts from normal epithelium with that from CIN and invasive carcinoma showed significant increases in pre-cancerous lesions and invasive cancer (p < 0.0001). Microvessel density, assessed by CD31 immunostaining, was found to be associated with the overall survival in women with clinical stage IB cervical carcinoma (p < 0.03). There was a significant association of microvessel density (p < 0.05) with relapse-free survival in patients with regional lymph node metastasis.

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July 1997
Volume 11 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Dellas A, Moch H, Schultheiss E, Feichter G, Almendral A, Gudat F and Torhorst J: Association of tumor induced vascularization with clinicopathological parameters in cervical neoplasm. Int J Oncol 11: 105-109, 1997
APA
Dellas, A., Moch, H., Schultheiss, E., Feichter, G., Almendral, A., Gudat, F., & Torhorst, J. (1997). Association of tumor induced vascularization with clinicopathological parameters in cervical neoplasm. International Journal of Oncology, 11, 105-109. https://doi.org/10.3892/ijo.11.1.105
MLA
Dellas, A., Moch, H., Schultheiss, E., Feichter, G., Almendral, A., Gudat, F., Torhorst, J."Association of tumor induced vascularization with clinicopathological parameters in cervical neoplasm". International Journal of Oncology 11.1 (1997): 105-109.
Chicago
Dellas, A., Moch, H., Schultheiss, E., Feichter, G., Almendral, A., Gudat, F., Torhorst, J."Association of tumor induced vascularization with clinicopathological parameters in cervical neoplasm". International Journal of Oncology 11, no. 1 (1997): 105-109. https://doi.org/10.3892/ijo.11.1.105