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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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July 1997 Volume 11 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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July 1997 Volume 11 Issue 1

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Article

High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer

  • Authors:
    • G CodacciPisanelli
    • P Seminara
    • L Gargano
    • M Accordino
    • E Sbaffi
    • V Bonaiuti
    • R Rossetti
    • F Franchi
  • View Affiliations / Copyright

    Affiliations: UNIV ROMA LA SAPIENZA,DEPT CLIN MED,I-00185 ROME,ITALY. UNIV ROMA LA SAPIENZA,DEPT SURG PATHOL 4,I-00185 ROME,ITALY. CASILINO HOSP,ROME,ITALY. MIL HOSP ATTILIO FRIGERI,ROME,ITALY.
  • Pages: 25-29
    |
    Published online on: July 1, 1997
       https://doi.org/10.3892/ijo.11.1.25
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Abstract

A chemotherapy regimen based on high doses of BCNU and mitomycin C with autologous bone marrow transplantation was used in 18 patients with advanced colorectal carcinoma. Haematological toxicity was manageable, with a short nadir for white blood cells and platelets. The response rate was 33%, with a prevalence in peritoneal lesions compared to liver or lung metastases. Extra-haematological toxicity appeared in 16% of cases: a case of veno-occlusive disease of the liver and two cases of lung impairment are discussed. Although the response rate obtained with the regimen was satisfactory, the more extensive use of high-dose chemotherapy followed by autologous bone marrow transplantation requires the identification of less toxic protocols.

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Copy and paste a formatted citation
Spandidos Publications style
CodacciPisanelli G, Seminara P, Gargano L, Accordino M, Sbaffi E, Bonaiuti V, Rossetti R and Franchi F: High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer. Int J Oncol 11: 25-29, 1997.
APA
CodacciPisanelli, G., Seminara, P., Gargano, L., Accordino, M., Sbaffi, E., Bonaiuti, V. ... Franchi, F. (1997). High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer. International Journal of Oncology, 11, 25-29. https://doi.org/10.3892/ijo.11.1.25
MLA
CodacciPisanelli, G., Seminara, P., Gargano, L., Accordino, M., Sbaffi, E., Bonaiuti, V., Rossetti, R., Franchi, F."High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer". International Journal of Oncology 11.1 (1997): 25-29.
Chicago
CodacciPisanelli, G., Seminara, P., Gargano, L., Accordino, M., Sbaffi, E., Bonaiuti, V., Rossetti, R., Franchi, F."High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer". International Journal of Oncology 11, no. 1 (1997): 25-29. https://doi.org/10.3892/ijo.11.1.25
Copy and paste a formatted citation
x
Spandidos Publications style
CodacciPisanelli G, Seminara P, Gargano L, Accordino M, Sbaffi E, Bonaiuti V, Rossetti R and Franchi F: High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer. Int J Oncol 11: 25-29, 1997.
APA
CodacciPisanelli, G., Seminara, P., Gargano, L., Accordino, M., Sbaffi, E., Bonaiuti, V. ... Franchi, F. (1997). High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer. International Journal of Oncology, 11, 25-29. https://doi.org/10.3892/ijo.11.1.25
MLA
CodacciPisanelli, G., Seminara, P., Gargano, L., Accordino, M., Sbaffi, E., Bonaiuti, V., Rossetti, R., Franchi, F."High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer". International Journal of Oncology 11.1 (1997): 25-29.
Chicago
CodacciPisanelli, G., Seminara, P., Gargano, L., Accordino, M., Sbaffi, E., Bonaiuti, V., Rossetti, R., Franchi, F."High-dose chemotherapy with bone marrow transplantation for advanced colorectal cancer". International Journal of Oncology 11, no. 1 (1997): 25-29. https://doi.org/10.3892/ijo.11.1.25
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