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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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November 1997 Volume 11 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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November 1997 Volume 11 Issue 5

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Article

Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status

  • Authors:
    • M Bache
    • J Dunst
    • P Wurl
    • D Frode
    • M Dietzel
    • A Meye
    • H Schmidt
    • F Rath
    • W Wohlrab
    • H Dralle
    • H Taubert

  • View Affiliations / Copyright

    Affiliations: UNIV HALLE WITTENBERG,INST PATHOL,D-060979 HALLE,GERMANY. UNIV HALLE WITTENBERG,DEPT RADIOTHERAPY,HALLE,GERMANY. UNIV HALLE WITTENBERG,CLIN GEN SURG,HALLE,GERMANY. UNIV HALLE WITTENBERG,DEPT DERMATOL,HALLE,GERMANY.
  • Pages: 993-997
    |
    Published online on: November 1, 1997
       https://doi.org/10.3892/ijo.11.5.993
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Abstract

We investigated a wild-type (wt) p53 rhabdomyosarcoma (A-204) and a mutated (mt p53) undifferentiated sarcoma cell line (US8-93) for their response to X-rays. The observation period was 0 to 96 h after irradiation. Both cell lines showed a strikingly delayed G2/M arrest and an induction of apoptosis after irradiation. Compared with the cell line A-204 (wt p53), the cell line US8-93 (mt p53) revealed a stronger G2/M arrest. In agreement with this, in terms of viability as well as the rate of apoptosis, A-204 (wt p53) showed a stronger response to irradiation than US8-93 (mt p53). We suggest that the different p53 gene status might be the cause for a different response to irradiation.

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Copy and paste a formatted citation
Spandidos Publications style
Bache M, Dunst J, Wurl P, Frode D, Dietzel M, Meye A, Schmidt H, Rath F, Wohlrab W, Dralle H, Dralle H, et al: Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status. Int J Oncol 11: 993-997, 1997.
APA
Bache, M., Dunst, J., Wurl, P., Frode, D., Dietzel, M., Meye, A. ... Taubert, H. (1997). Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status. International Journal of Oncology, 11, 993-997. https://doi.org/10.3892/ijo.11.5.993
MLA
Bache, M., Dunst, J., Wurl, P., Frode, D., Dietzel, M., Meye, A., Schmidt, H., Rath, F., Wohlrab, W., Dralle, H., Taubert, H."Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status". International Journal of Oncology 11.5 (1997): 993-997.
Chicago
Bache, M., Dunst, J., Wurl, P., Frode, D., Dietzel, M., Meye, A., Schmidt, H., Rath, F., Wohlrab, W., Dralle, H., Taubert, H."Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status". International Journal of Oncology 11, no. 5 (1997): 993-997. https://doi.org/10.3892/ijo.11.5.993
Copy and paste a formatted citation
x
Spandidos Publications style
Bache M, Dunst J, Wurl P, Frode D, Dietzel M, Meye A, Schmidt H, Rath F, Wohlrab W, Dralle H, Dralle H, et al: Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status. Int J Oncol 11: 993-997, 1997.
APA
Bache, M., Dunst, J., Wurl, P., Frode, D., Dietzel, M., Meye, A. ... Taubert, H. (1997). Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status. International Journal of Oncology, 11, 993-997. https://doi.org/10.3892/ijo.11.5.993
MLA
Bache, M., Dunst, J., Wurl, P., Frode, D., Dietzel, M., Meye, A., Schmidt, H., Rath, F., Wohlrab, W., Dralle, H., Taubert, H."Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status". International Journal of Oncology 11.5 (1997): 993-997.
Chicago
Bache, M., Dunst, J., Wurl, P., Frode, D., Dietzel, M., Meye, A., Schmidt, H., Rath, F., Wohlrab, W., Dralle, H., Taubert, H."Radiation induced G2/M block and apoptosis in two human sarcoma cell lines with different p53 gene status". International Journal of Oncology 11, no. 5 (1997): 993-997. https://doi.org/10.3892/ijo.11.5.993
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