Experimental animal models of pancreatic cancer (review).

  • Authors:
    • Q Shi
    • K Xie
  • View Affiliations

  • Published online on: August 1, 2000     https://doi.org/10.3892/ijo.17.2.217
  • Pages: 217-242
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Abstract

Pancreatic adenocarcinoma is currently the fifth leading cause of cancer-related death in the United States and is largely refractory to conventional therapies. The average survival from diagnosis to death is 4-6 months. The major cause of death is rapid development of metastasis involving the lymph nodes, liver, lungs, or peritoneum. To understand its etiology and eventually to make prevention possible and effective, appropriate carcinogenesis models will certainly help shed more light on the process of pancreatic carcinogenesis and help us understand the effects of environmental and genetic elements on pancreatic cancer development. The development of new treatment strategies to control cancer metastasis is of immediate urgency. Fulfillment of this difficult task relies on our knowledge of the cellular and molecular biology of pancreatic cancer metastasis, and the use of relevant animal models will certainly help define each aspect of this complicated process.

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Aug 2000
Volume 17 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Shi Q and Shi Q: Experimental animal models of pancreatic cancer (review).. Int J Oncol 17: 217-242, 2000
APA
Shi, Q., & Shi, Q. (2000). Experimental animal models of pancreatic cancer (review).. International Journal of Oncology, 17, 217-242. https://doi.org/10.3892/ijo.17.2.217
MLA
Shi, Q., Xie, K."Experimental animal models of pancreatic cancer (review).". International Journal of Oncology 17.2 (2000): 217-242.
Chicago
Shi, Q., Xie, K."Experimental animal models of pancreatic cancer (review).". International Journal of Oncology 17, no. 2 (2000): 217-242. https://doi.org/10.3892/ijo.17.2.217